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KRLSGWDSVLLYSEAPNVHMHTIKAAVIELDADRRSLDVAAFRQVIAGRLNKLDPFCYQLVEVPFSFHHP MWRENCEIDLDYHIRPWRVSPPGGRRELDEAIGQIASTPLDRSRPLWEMYFVEGLANNRIAVVGKIHHAL ADGVASANLLARGMDLQPGPEAGPYVCDPPPTTRQLMVSAFADHLRHVGRLPHTIRYTAQGLGRVRRSAR KLSPELTRPFEPPPTFMNHKLTPERRFATATLALADVKETGKRLGATINDMVLAMSTGALRTLLLRYDGQ AQPLLASVPVSFDFSPERISGNRFTGMLVALPVDHDDPLERVAACHQNAISAKESHQLMGPELVSRWAAY MPPAPTRAFFQWASARDGHNKILNLNISNVPGPRERGRVGGALVTEIYSVGPLTAGSGLNITVWSYVDQL NISVLTDGATCKDPHEVTEAMVQDFIEIRRAAGFSEDLTVVEAAMAPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4952 | - | - | 100% (469) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. avium 104 | MAV_1847 | - | e-142 | 55.90% (458) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. avium 104 | MAV_2240 | - | 1e-55 | 33.19% (470) | acyltransferase, ws/dgat/mgat subfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0227 | - | 1e-106 | 76.07% (234) | hypothetical protein Mb0227 |
| M. gilvum PYR-GCK | Mflv_0439 | - | 0.0 | 71.28% (470) | hypothetical protein Mflv_0439 |
| M. tuberculosis H37Rv | Rv0221 | - | 0.0 | 80.38% (469) | hypothetical protein Rv0221 |
| M. leprae Br4923 | MLBr_01244 | - | 2e-27 | 26.91% (405) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_0507 | - | 1e-56 | 31.26% (467) | hypothetical protein MAB_0507 |
| M. marinum M | MMAR_0464 | - | 0.0 | 81.45% (469) | hypothetical protein MMAR_0464 |
| M. smegmatis MC2 155 | MSMEG_0290 | - | 0.0 | 71.49% (470) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_3760 | - | 0.0 | 72.13% (470) | PUTATIVE Diacylglycerol O-acyltransferase |
| M. ulcerans Agy99 | MUL_1313 | - | 8e-56 | 30.96% (491) | hypothetical protein MUL_1313 |
| M. vanbaalenii PYR-1 | Mvan_0228 | - | 0.0 | 72.42% (475) | hypothetical protein Mvan_0228 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0227|M.bovis_AF2122/97 ----------MKRLSGWDAVLLYSET-PNVHMHTLKVAVIELDS-----D
Rv0221|M.tuberculosis_H37Rv ----------MKRLSGWDAVLLYSET-PNVHMHTLKVAVIELDS-----D
MMAR_0464|M.marinum_M ----------MKRLSGWDAVLLYSET-PNVHMHTLKVAVIELDP-----D
MAV_4952|M.avium_104 ----------MKRLSGWDSVLLYSEA-PNVHMHTIKAAVIELDA-----D
Mflv_0439|M.gilvum_PYR-GCK ----------MKRLRGWDAVLLYSET-PSVHMHTLKLAVIELDD----LG
Mvan_0228|M.vanbaalenii_PYR-1 ----------MKRLSGWDAVLLYSET-PNVHMHTLKLAVIELDDTFAREG
TH_3760|M.thermoresistible__bu ----------VKRLQGWDAVLLYSET-PNVHMHTLKVAVIDLSD-----V
MSMEG_0290|M.smegmatis_MC2_155 ----------MQRLSGWDAFLLYSET-PNVHMHTLKIAIIDLEG----IG
MAB_0507|M.abscessus_ATCC_1997 ----------MQRLSGVDAAFWHAET-AGWHMHIGGLSIYDP------TD
MUL_1313|M.ulcerans_Agy99 ----------MRRLSSVDAQFFAMED-GRNHSHVCQLTIVEATT----TD
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTP------
. .* . * : * : : :
Mb0227|M.bovis_AF2122/97 RQEFGVDAFREVIAGRLHKLEPLGYQLVDVPLKFHHPMWREHCQVDLNYH
Rv0221|M.tuberculosis_H37Rv RQEFGVDAFREVIAGRLHKLEPLGYQLVDVPLKFHHPMWREHCQVDLNYH
MMAR_0464|M.marinum_M RRAFGVDAFRAVIGERMAKLEPFGYQLVDIPFKFHHPMWREHCEVDLDYH
MAV_4952|M.avium_104 RRSLDVAAFRQVIAGRLNKLDPFCYQLVEVPFSFHHPMWRENCEIDLDYH
Mflv_0439|M.gilvum_PYR-GCK GAKFGVEELRKVIHGRLYKLDPFRYELVDIPFKFHHPMWRENAEVDLDYH
Mvan_0228|M.vanbaalenii_PYR-1 GATFGVEELRKVIHGRLYKLDPFRYQLIDIPFKFHHPMWRENAEVDLEYH
TH_3760|M.thermoresistible__bu THPFGLEDFRKVIASRLYKLDPFRYQLVEIPFKFHHPMWRENCEVDLDHH
MSMEG_0290|M.smegmatis_MC2_155 DRTFGVEDFRKVLRGRLHKLDPFRFQLVDIPFKFHHPMWRENCDVDLEYH
MAB_0507|M.abscessus_ATCC_1997 APDYSFERVRALIVERLPSMPQLRWRVTDVPLGLDRPWFVEDEELDPDFH
MUL_1313|M.ulcerans_Agy99 GLRLDGQRIRGLLAQRIDLMPPLRWRVREVPFGIDYPVLVQDDTFDLDSH
MLBr_01244|M.leprae_Br4923 ----DWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFH
. .* : : : .: .: * . .: : *
Mb0227|M.bovis_AF2122/97 IRPWRLRAPGGRRELDEAVGEIASTPLNRDHPLWEMYFVEGLANHRIAVV
Rv0221|M.tuberculosis_H37Rv IRPWRLRAPGGRRELDEAVGEIASTPLNRDHPLWEMYFVEGLANHRIAVV
MMAR_0464|M.marinum_M IRPWQLRPPGGRRELDEAIGEIASTPLDRRYPLWEMYFVEGLANHRVAVV
MAV_4952|M.avium_104 IRPWRVSPPGGRRELDEAIGQIASTPLDRSRPLWEMYFVEGLANNRIAVV
Mflv_0439|M.gilvum_PYR-GCK VRSVRVDAPGGRRELDEAVGRIASTPLDRSRPLWEMYLIEGLADGRIAVL
Mvan_0228|M.vanbaalenii_PYR-1 VRSCRVDAPGGRRELDEAVGRIASTPLDRSRPLWEMYLIEGLAGGRIAVL
TH_3760|M.thermoresistible__bu IRGMRVDPPGGRRELDEAVGRIASTPLDRRYPLWEMYFVEGLANGRVAVV
MSMEG_0290|M.smegmatis_MC2_155 VRPWQVRAPGGRRELDEAIGEIAGTPLDRSRPLWEMYFVEGLAGGRIAVV
MAB_0507|M.abscessus_ATCC_1997 IRRIGVPAPGGRKELEELAGRLMSYKLDRSRPLWELWVIEGVEGGRVATL
MUL_1313|M.ulcerans_Agy99 LWESALPAPGDDEQLGRAVADIASRPLDRARPLWELHVIHGLAGDRVALV
MLBr_01244|M.leprae_Br4923 VRRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAML
: : ** .:: : :: *** .:.*: * * :
Mb0227|M.bovis_AF2122/97 AKIHHALADGVASANMMARGMDLLPGPE------------VGR--YVPDP
Rv0221|M.tuberculosis_H37Rv AKIHHALADGVASANMMARGMDLLPGPE------------VGR--YVPDP
MMAR_0464|M.marinum_M GKIHHALADGVASANLMARGMDLLPGPE------------GDP--YVSDP
MAV_4952|M.avium_104 GKIHHALADGVASANLLARGMDLQPGPE------------AGP--YVCDP
Mflv_0439|M.gilvum_PYR-GCK GKIHHALADGVASANLLARGMDLQDGPQ------------VDRDSYATDP
Mvan_0228|M.vanbaalenii_PYR-1 GKIHHALADGVASANLLARGMDLQDSPQ------------ADRDSYATDP
TH_3760|M.thermoresistible__bu GKIHHALADGVASGNLMARGMDLQPGPQ------------RDHTFYRTDP
MSMEG_0290|M.smegmatis_MC2_155 NKIHHALADGIASANLLARGMDLREGPQ------------RDRDSYVTDP
MAB_0507|M.abscessus_ATCC_1997 TKMHHAIVDGVSGAGLGEILLDIAPEPRPAPDDT---VGSLVGLGLPSRE
MUL_1313|M.ulcerans_Agy99 TKLHHSVIDGVSGMELLGALLDTVSFPDAGPELEKPPTGTAIGN-ASSDA
MLBr_01244|M.leprae_Br4923 LQISHAITDGVGSVEMFAEMYDLERDPPSRPRSP------QPIPQDLSRN
:: *:: **:.. : * *
Mb0227|M.bovis_AF2122/97 APTKRQLLSAAFIDHLRHLGRIPATIRYTTQG------------------
Rv0221|M.tuberculosis_H37Rv APTKRQLLSAAFIDHLRHLGRIPATIRYTTQG------------------
MMAR_0464|M.marinum_M APTKRELMSSAFLDHLRHLGRIPATMRYTAQG------------------
MAV_4952|M.avium_104 PPTTRQLMVSAFADHLRHVGRLPHTIRYTAQG------------------
Mflv_0439|M.gilvum_PYR-GCK APSKGELVRTAFTDHLRQIRRFPDVVRYTAAG------------------
Mvan_0228|M.vanbaalenii_PYR-1 APTRGELVRSAFTDHLRQIAKLPGVVRYTAQG------------------
TH_3760|M.thermoresistible__bu PPGRSHLVRTAFVDHLRQIGRIPSVMRYTYDG------------------
MSMEG_0290|M.smegmatis_MC2_155 EPSKGELVRTAFADHMRQIGRIPATIRYTAQG------------------
MAB_0507|M.abscessus_ATCC_1997 RILLSALVNVGVKTPYRVARLVQQTVR-----------------------
MUL_1313|M.ulcerans_Agy99 GLLARALASLPVQ-PARMVRGLPPMLRHIDQLPTMRHLPGAAVIAKVADR
MLBr_01244|M.leprae_Br4923 DLMLQGINHLPVALAGGVVGGLSGVASVAGRAILR-------------PA
: . .
Mb0227|M.bovis_AF2122/97 LGRVRRSSRKLSPALTMPFTPPPTFMNR----------------------
Rv0221|M.tuberculosis_H37Rv LGRVRRSSRKLSPALTMPFTPPPTFMNHRLTPERRFATATLALIDVKATA
MMAR_0464|M.marinum_M LARVRRSSRKLSPELTRPFTPPPTFMNHMLTPQRRFATATLALADVKQTG
MAV_4952|M.avium_104 LGRVRRSARKLSPELTRPFEPPPTFMNHKLTPERRFATATLALADVKETG
Mflv_0439|M.gilvum_PYR-GCK MRRVRSSGQKLSPELTRPFTPPPSFMNHQIDATRKFATATLALDDVKQTG
Mvan_0228|M.vanbaalenii_PYR-1 VRRVQRSERKLSPELTRPFTPPPTFMNHMVDATRRFATATVALDDVKQTG
TH_3760|M.thermoresistible__bu LRRVHRSTRKLSPELTRPFTPPPTFLNHKIDATRTFATATLALSDVKATS
MSMEG_0290|M.smegmatis_MC2_155 VARVRRSSRKLSPELTRPFTPPPSFINHMITSKRKFATATIALADAKETS
MAB_0507|M.abscessus_ATCC_1997 -QQLAVFGMERKSPGY--FEAPHTRFNAPVSPHRRISGARLDLARVKALK
MUL_1313|M.ulcerans_Agy99 AERLATRNKDGRNLQHPRAAAPKVSFGGRISAQRRFAFGSLPLDQIKAAK
MLBr_01244|M.leprae_Br4923 STVSGVVGYVRSGIRVLSQAAEPSPLLRQRSLATRTEAIEIQLSDLHKAA
. :
Mb0227|M.bovis_AF2122/97 -------------------IKKPLSKPSGRPP-PHTNRAPSS--------
Rv0221|M.tuberculosis_H37Rv KLL-GATINDMVLAMSTGALRTLLLRYDGKAE-PLLASVPVSYDF-SPER
MMAR_0464|M.marinum_M KQL-GATINDMVLAMSTGALRNLLLRYDGRAE-PLLASVPVSYDF-SPDR
MAV_4952|M.avium_104 KRL-GATINDMVLAMSTGALRTLLLRYDGQAQ-PLLASVPVSFDF-SPER
Mflv_0439|M.gilvum_PYR-GCK KHL-GATINDMVLAMSAGTLRKLLLRYDGQADHPLLASVPVSFDF-SRDR
Mvan_0228|M.vanbaalenii_PYR-1 KQL-GVTINDMVLAMSAGALRKLLLRYDGRADHALLASVPVSFDF-SRDR
TH_3760|M.thermoresistible__bu RHL-GVTINDLVLALSAGALRKLLLRYDGHADHPLLASVPVSFDF-SPDR
MSMEG_0290|M.smegmatis_MC2_155 KKL-GITLNDLVLAMSSGALRTLQLRYDGRADHPLLASVPMSFDF-SPDR
MAB_0507|M.abscessus_ATCC_1997 DAF-GVKVNDVVLAIVAGAVRDYLAKRDEFPDKPLIVQIPVSVRTEETDG
MUL_1313|M.ulcerans_Agy99 FAVPGATVNDVVVAVCAGALRRRMIARGDDVATPLVAMVPVSVRTGERQ-
MLBr_01244|M.leprae_Br4923 KAG-DGSINDAYLAGLVGALRRYHEALGVSIS-TLPMAVPVNVRT-EADV
:: . . * .
Mb0227|M.bovis_AF2122/97 --------MPLAM-------------------------------------
Rv0221|M.tuberculosis_H37Rv ISGNRFTGMLVALPADSDDPLQRVRVCHENAVSAKESHQLLGPELISRWA
MMAR_0464|M.marinum_M ISGNYFSGMMVALPTDCADPLERVQACHENALSAKESHQLLGPELISRWA
MAV_4952|M.avium_104 ISGNRFTGMLVALPVDHDDPLERVAACHQNAISAKESHQLMGPELVSRWA
Mflv_0439|M.gilvum_PYR-GCK ISGNYFTGVLVSIPVELDDPVERVRAAHDAAVAGKESNNLLGPELVSQWS
Mvan_0228|M.vanbaalenii_PYR-1 ISGNYFTGVLVSLPVDVEDPLERVSAAHTAAAAGKESNNLIGPELVSRWS
TH_3760|M.thermoresistible__bu ICGNYFTGMLVALPVDTAEPLDRIRATRDAALLAKESHQLIGPELISRWS
MSMEG_0290|M.smegmatis_MC2_155 IWGNRFSGVLVALPVDVADTGERVRRTREAANLAKESHQLIGPELVARWA
MAB_0507|M.abscessus_ATCC_1997 VVGNQVSSMTVSLATDIDDPAERIQAIYEGTQGAKEMARAMSAHQIMGLT
MUL_1313|M.ulcerans_Agy99 -YGNQISSMIVPIPTDQADARARLISAHQVMRAAKERHRAIPAKLLTEAN
MLBr_01244|M.leprae_Br4923 VGSNRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLM
: :.
Mb0227|M.bovis_AF2122/97 --------------------------------------------------
Rv0221|M.tuberculosis_H37Rv AYWPPAGAEALFRWLSERDGQNKVLN---LNISNVPGPRERGRVGAALVT
MMAR_0464|M.marinum_M AYWPPGATEAAFRWASSRDGQNKVLN---LNISNVPGPREHGRVGGALVT
MAV_4952|M.avium_104 AYMPPAPTRAFFQWASARDGHNKILN---LNISNVPGPRERGRVGGALVT
Mflv_0439|M.gilvum_PYR-GCK AYLPPAPAEALFRWLGTKDGQNKVMN---LPISNVPGPRERARVGGALVT
Mvan_0228|M.vanbaalenii_PYR-1 AYFPPAPAEAMFRWLSNKDGQNKVMN---LPISNVPGPRERARVGGALVT
TH_3760|M.thermoresistible__bu QYLPPAPAERLFGWLSRIDGQNKIQN---LTVSNVMGPKERGRVGGALVT
MSMEG_0290|M.smegmatis_MC2_155 AYMPPVPVEALFKRLSSKDGQNKVLN---LNISNVPGPRERGKVGGATVT
MAB_0507|M.abscessus_ATCC_1997 DTTPPGLLQLAARAYTAS-GLSRNLAPINLVLSNVPGPSFPLYMAGARLE
MUL_1313|M.ulcerans_Agy99 HTVPPALLTRAARVISMTTGSGWIRPPFNVTISNIPGSPDPLYCAGARVV
MLBr_01244|M.leprae_Br4923 TVLPASVLDFIVDSVASS----------DVNASNIPAYPGDTYFAGAKIL
Mb0227|M.bovis_AF2122/97 --------------------------------------------------
Rv0221|M.tuberculosis_H37Rv EIYSVGPLTAGSGLNITVWSYVDQLNISVLTDGSTVQDPHEVTAGMIADF
MMAR_0464|M.marinum_M EIYSVGPLTAGSGLNITVWSYVDQLNISVLTDGATVEDPHEVTEAMMADF
MAV_4952|M.avium_104 EIYSVGPLTAGSGLNITVWSYVDQLNISVLTDGATCKDPHEVTEAMVQDF
Mflv_0439|M.gilvum_PYR-GCK EIYSVGPLTVGSGINITVWSYVDQLNISVLTDGKTLEDPHELTSAMLDDF
Mvan_0228|M.vanbaalenii_PYR-1 EIYSVGPLTAGSGLNITVWSYVDQINISVLSDGKTLDDPHELTTAMVDEF
TH_3760|M.thermoresistible__bu EIYSVGPLTAASGLNITVWSYVDQLNISVLSDGSTFDDPHEVTDAMVGEF
MSMEG_0290|M.smegmatis_MC2_155 ELYSVGPITAGSGLNITVWSYVDQLNISVISDDATVDDPHEVTDAMLDEF
MAB_0507|M.abscessus_ATCC_1997 SMIPLGPPVMDVALNITCFSYLEHMDFGFVTTPEVAADIDEMADGLEAAL
MUL_1313|M.ulcerans_Agy99 SQHPVNVLLDGMGLSITLLSYQDRLDFGLTADRELLPDVWHLADELAAEL
MLBr_01244|M.leprae_Br4923 RQYGIGPR-PGVAMMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGF
Mb0227|M.bovis_AF2122/97 -----------------------------------
Rv0221|M.tuberculosis_H37Rv IEIRRAAGLSVELTVVESAMAQA------------
MMAR_0464|M.marinum_M VEIRRAAGLSAELTVIEAAMAQARSMNEGAGSA--
MAV_4952|M.avium_104 IEIRRAAGFSEDLTVVEAAMAPA------------
Mflv_0439|M.gilvum_PYR-GCK VEIRRAAGLSEELTVVETALPN-------------
Mvan_0228|M.vanbaalenii_PYR-1 IEIRRAAGLSTELTVIETAMAN-------------
TH_3760|M.thermoresistible__bu IEIRGAAGLPGELTVVETAMAR-------------
MSMEG_0290|M.smegmatis_MC2_155 REIRRTAGLSEKLTVVETAMPQ-------------
MAB_0507|M.abscessus_ATCC_1997 VELEHAVGI--------------------------
MUL_1313|M.ulcerans_Agy99 SALAAEVGAPRNPVADGAPTSTTGRPTAKPGAIPR
MLBr_01244|M.leprae_Br4923 DEVLALAGDPTPHAVPASFAARSSGSPAGWLSSS-