For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_1659 (-)

annotation: mmpl family protein
coordinates: 1629127 - 1631481
length: 784

VMAMLRVITRLAIAAPRRIIGIAVLVMVGAAIFGLPVVNSLSGGGFQDPTSESARATEILRDRFNQTDQQ
MLIVVSAPDGARSPQAHRVGTDIVDKLKNSPWVMSVSSAWTSPPAAAAQLISKDNKSGMIVAGLKGGEND
AQKYASTLTRELVHDRDGVTVRAGGMAVAYAQINAQNQRDLLLMESIAIPLSFAVLVWVLGGVVAATLPV
VLGALAIVGTMSVLRLISFATDVSTYALDLSIAMGLALAIDYNLLIITRYREELARTEDRDRALYRTMAT
AGRTVLFSATTVGLSMAVMAVFPMYFLKSSAYTIVATAIIVAIAAVVITPAAIVLLGPRLDTMDARRVMH
RILHGQRSFRDPAHKPLVEQFWYRSTKYVLRRAVPVGLSVVALLLLLGVPFLGVKWGFPDERVLPRSASA
RQVADMLDNDFPGLGTELSVVVPDARGVTPAELRKYAAELSRVPDVSAVSAPTGTFSAGHRVGPPAAATG
LANGSAFFTVSSTAPLYSPASNAQLDRLHQVAGPGGRAVQMTGLAQINRDSVEAITKRLPTVFGLIAVVT
FMLLFLLTGSAVLPVQALVCNVLSLTAAFGAMVWIFQDGHLGALGTTPNGTLNANIPVLLFCIAFGLAMD
YEVFLVSRIHEYWLASQSIRETPPTAREARAETDESTALGIAGIGRVVTTAAVVMSISFAALIPAHVSFM
RMLGLGLTLGVLVDATLVRMVLVPAFIHLLGRWTWWAPRPMVWLRERSATGEAGEVRVGRRRWARDAPRP
AIRRWPSRATSGRG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1659--100% (784)mmpl family protein
M. avium 104MAV_1287-0.064.24% (797) mmpL protein
M. avium 104MAV_4968-8e-8528.64% (789) MmpL3 protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1177mmpL130.068.16% (760) transmembrane transport protein MmpL13
M. gilvum PYR-GCKMflv_2131-0.062.43% (756) MMPL domain-containing protein
M. tuberculosis H37RvRv1146mmpL13b1e-17369.04% (449) transmembrane transport protein MmpL13B
M. leprae Br4923MLBr_02620-6e-8828.89% (758) hypothetical protein MLBr_02620
M. abscessus ATCC 19977MAB_1287-0.054.09% (745) MmpL family membrane protein
M. marinum MMMAR_4305mmpL130.065.10% (788) transmembrane transport protein MmpL13
M. smegmatis MC2 155MSMEG_5178-0.061.99% (755) integral membrane protein
M. thermoresistible (build 8)TH_1538-0.054.33% (786) PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B
M. ulcerans Agy99MUL_0989mmpL130.064.59% (788) transmembrane transport protein MmpL13
M. vanbaalenii PYR-1Mvan_4573-0.064.16% (759) MMPL domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1177|M.bovis_AF2122/97            ---MLQRIARLAIAAPRRIIGFAVFVFIAAAVFGVPVADSLSPGGFQDPR
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               ---MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSPGGFQDPN
MUL_0989|M.ulcerans_Agy99           ---MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSRGGFQDPN
MAV_1659|M.avium_104                MMAMLRVITRLAIAAPRRIIGIAVLVMVGAAIFGLPVVNSLSGGGFQDPT
Mflv_2131|M.gilvum_PYR-GCK          ---MLHRIARLAIAAPRRVLMAALLVAIACGVFGIPVVTHLSAGGFQDPT
Mvan_4573|M.vanbaalenii_PYR-1       ---MLHRIALLAIAAPRRVLVVALLIMVGCGIFGAPVAKHLSAGGFQDPT
MSMEG_5178|M.smegmatis_MC2_155      ---MLQRIATTAIAAPRRILVVAALVMIAAGIFGIPVANKLSAGGFQDPT
TH_1538|M.thermoresistible__bu      ---MLETLARRIVAAPRRVLALVVLVIVGAAMFGLPVAGSLSAGGFRDPH
MAB_1287|M.abscessus_ATCC_1997      --MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPN
MLBr_02620|M.leprae_Br4923          ---MFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHVTQSGFYDDS
                                                                                      

Mb1177|M.bovis_AF2122/97            SESARAIEVLTDKFGQSGQKMLIVVTAA---AGADSPPAREVGTDIVEVL
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               AESARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAEL
MUL_0989|M.ulcerans_Agy99           AESARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAEL
MAV_1659|M.avium_104                SESARATEILRDRFNQTDQQMLIVVSAP---DGARSPQAHRVGTDIVDKL
Mflv_2131|M.gilvum_PYR-GCK          SESARATQMLVDTFGQGDMELILAVTSD---DGAQSPAARDVGVELVERL
Mvan_4573|M.vanbaalenii_PYR-1       SESARATQLLVDKFDQGDMELLISITDDNSADGANSPAARAVGTDLADRL
MSMEG_5178|M.smegmatis_MC2_155      AESARATQLLADKFHRGDMQLVIAVTAEAPGGRADGGRAREVGTEIVSEL
TH_1538|M.thermoresistible__bu      SESAQASALLAERFDQTDMQLLVTVSSS---AGVYGEAARRVGTEIVAAL
MAB_1287|M.abscessus_ATCC_1997      SESAYVTKALRDKFDISDQSLVFMLTSE---QGVKSPQMRAVAADLERQL
MLBr_02620|M.leprae_Br4923          SQSVKASILGDQVYGRDRSGHIVAIFHAPDGKTVNDPAWAKKITDELNQF
                                                                                      

Mb1177|M.bovis_AF2122/97            R--RSPLVYNVTSPWTVP---PTAAADLLSTDGKSGLIVVNVKGGENDAQ
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               N--HSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQ
MUL_0989|M.ulcerans_Agy99           N--HSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQ
MAV_1659|M.avium_104                K--NSPWVMSVSSAWTSP---PAAAAQLISKDNKSGMIVAGLKGGENDAQ
Mflv_2131|M.gilvum_PYR-GCK          S--DSPHVAAITSAWTSP---PSAAPALISEDGRTGLIVAGITGGESGAQ
Mvan_4573|M.vanbaalenii_PYR-1       A--ASPHVGAVTSAWTAP---PSAAPALVSEDGRTGLIIAGITGGESEAQ
MSMEG_5178|M.smegmatis_MC2_155      K--ASPYVTEVTSAWTAP---PSAAAALVSKDARTGLIVAGLNGGENGAQ
TH_1538|M.thermoresistible__bu      E--ASPQVAGVQSPWTVP---PGAGDRLVSEDATAGLIVAPIRGNETESS
MAB_1287|M.abscessus_ATCC_1997      K--DSGVVINLTSAWTAP---PQVAEELLGADGKAGLIVAGLTGGENDAQ
MLBr_02620|M.leprae_Br4923          QRNNSNKVTGWAGYLRASDTTNTVVQGMATPDKKYTFVSIPLKGDDDDTI
                                                                                      

Mb1177|M.bovis_AF2122/97            NHAQTLSDEVAHDRDGVTVRAGGSAMEYAQINRQNKDDLLVMELIAIPLS
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               KNAQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLS
MUL_0989|M.ulcerans_Agy99           KNAQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLS
MAV_1659|M.avium_104                KYASTLTRELVHDRDGVTVRAGGMAVAYAQINAQNQRDLLLMESIAIPLS
Mflv_2131|M.gilvum_PYR-GCK          KLAKALTDELVYDRDGVTVRAGGAAMTYVQINTQTEKDLLLMESIAIPLS
Mvan_4573|M.vanbaalenii_PYR-1       KHAKTLTDELVRDRDGVTVRAGGVAMTYVQINTQSEKDLLMMESIAIPLS
MSMEG_5178|M.smegmatis_MC2_155      QHAKELTDQFVRDHDGVRVRAGGEAMIYVQINGQSEKDLLMMESIAIPLS
TH_1538|M.thermoresistible__bu      DIARQLAAAVGSDRDRVNVRAGGPALVNAQIDTQTEHDLLVMEAIAIPLS
MAB_1287|M.abscessus_ATCC_1997      KHAAKLIKSLAVDRDGVAVKAGGVATLYNQIVTQSEKDLLVMESIAIPIS
MLBr_02620|M.leprae_Br4923          LNNYKAIAPDLQKLDGGTVQLAGLDPIANALTSTIATDQRRMEVLALPLV
                                                                                      

Mb1177|M.bovis_AF2122/97            FLVLIWVFGGLLAAGLPMAQAVLAVVGSMAVLRLVTFATEVSTFALNLST
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               FLVLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLST
MUL_0989|M.ulcerans_Agy99           FLVLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLST
MAV_1659|M.avium_104                FAVLVWVLGGVVAATLPVVLGALAIVGTMSVLRLISFATDVSTYALDLSI
Mflv_2131|M.gilvum_PYR-GCK          FVVLVWVFGGLLAAALPLAVGVFAILGSMAVLRGFTLVTDVSIFALNLSI
Mvan_4573|M.vanbaalenii_PYR-1       FVVLVWVFGGLLAAALPLAVGAFAILGSMAVLRAVTLVTDVSIFALNLSI
MSMEG_5178|M.smegmatis_MC2_155      FVVLVWVFGGLLAAALPLAVGGFAILGSLAVLRLFTMVTDVSIFALNLTV
TH_1538|M.thermoresistible__bu      FVVLVWVFGGLLAAALPLAVGVLAIVGSMAVLRTFTMFTEVSVFALNLSI
MAB_1287|M.abscessus_ATCC_1997      FVVLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAV
MLBr_02620|M.leprae_Br4923          AVVLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPVHFFAQPVVS
                                                                                      

Mb1177|M.bovis_AF2122/97            ALGLALAIDYTLLIVSRYRDELAEGSDRDEALIRTMATSGRTVLFSAVTV
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               ALGLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTV
MUL_0989|M.ulcerans_Agy99           ALGLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTV
MAV_1659|M.avium_104                AMGLALAIDYNLLIITRYREELARTEDRDRALYRTMATAGRTVLFSATTV
Mflv_2131|M.gilvum_PYR-GCK          AMGLALAIDYTLLIISRYRDELADGHDRDTALLRTMTTAGRTVVFSATTV
Mvan_4573|M.vanbaalenii_PYR-1       AMGLALAIDYTLLIISRYRDELAEGHDRDSALVRTMMTAGRTVLFSALTV
MSMEG_5178|M.smegmatis_MC2_155      AMGLALAIDYTLLIISRFRDELAEGADRETALVRTMMTAGRTVLFSAMTV
TH_1538|M.thermoresistible__bu      AMGLALAIDYTLLLLNRYRDELAEGCSREQAVIRTMTSAGRTVIFSAVIV
MAB_1287|M.abscessus_ATCC_1997      AMGLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTV
MLBr_02620|M.leprae_Br4923          LIGLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLI
                                                                                      

Mb1177|M.bovis_AF2122/97            ALSMSATALFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGPRLDA
Rv1146|M.tuberculosis_H37Rv         ----------------------MATVAFVATASIVITPAAIVLLGPRLDA
MMAR_4305|M.marinum_M               ALSMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDA
MUL_0989|M.ulcerans_Agy99           ALSMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDA
MAV_1659|M.avium_104                GLSMAVMAVFPMYFLKSSAYTIVATAIIVAIAAVVITPAAIVLLGPRLDT
Mflv_2131|M.gilvum_PYR-GCK          ALSMVAMVLFPMYFLKSFAYAGIAVVSFAALAAIVVTPAAIALAGDRLDA
Mvan_4573|M.vanbaalenii_PYR-1       ALSMVAMVLFPMYFLKSFAYAGIAVVGFAAVAAIVVAPAAIVLAGARLDS
MSMEG_5178|M.smegmatis_MC2_155      ALSMVAMVLFPMYFLKSFAYAGIAVVALAATAAIVLTPAAIVLLGDRLDA
TH_1538|M.thermoresistible__bu      ATSMVPLALFPMYFLRSFAYAGVGVVAFALCAALVITPAAITVLGARLDS
MAB_1287|M.abscessus_ATCC_1997      ALALVALILFPMYFLKSFGYAGVAVVFVGAIAALVIVPAVVTLLGDRIDA
MLBr_02620|M.leprae_Br4923          AASGASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACLAILAKHVDA
                                                          :... .    ::.: ** :.: . ::*:

Mb1177|M.bovis_AF2122/97            LDVRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFV
Rv1146|M.tuberculosis_H37Rv         LDVRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFV
MMAR_4305|M.marinum_M               LNVRRLARRMLGRP-----------------EPQHKPVDQLFWYRSTKFV
MUL_0989|M.ulcerans_Agy99           LNVRRLARRMLGRP-----------------KPQHKPVDQLFWYRSTKFV
MAV_1659|M.avium_104                MDARRVMHRILHGQR-------------SFRDPAHKPLVEQFWYRSTKYV
Mflv_2131|M.gilvum_PYR-GCK          LDVRRLVRRILGRP-----------------DPVAKPVEQNFWYRSTTFV
Mvan_4573|M.vanbaalenii_PYR-1       MDVRRLVRRVLGRP-----------------EPVAKPVEQMFWYRSTKFV
MSMEG_5178|M.smegmatis_MC2_155      YDVRRFFRRVFGRP-----------------EPEPKPVEQGFWYRTAKAA
TH_1538|M.thermoresistible__bu      WDIRRLIRRLMRRTP-------------AAAEPAPRAVCGSKWYRWAKAV
MAB_1287|M.abscessus_ATCC_1997      LDVRRLIRRVLGRP-----------------EPVAKDVTQSFWYRTTKRV
MLBr_02620|M.leprae_Br4923          LGVRTLFRVPLLRNWRMSHACLNWLADRLQKTKTREEVEAGFWGKLVNFV
                                     . * . :  :                        . :    * :  . .

Mb1177|M.bovis_AF2122/97            MRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRD
Rv1146|M.tuberculosis_H37Rv         MRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRD
MMAR_4305|M.marinum_M               MRRALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRT
MUL_0989|M.ulcerans_Agy99           MRRALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRT
MAV_1659|M.avium_104                LRRAVPVGLSVVALLLLLGVPFLGVKWGFPDERVLPRSASARQVADMLDN
Mflv_2131|M.gilvum_PYR-GCK          MRRSIPIGGVVVVLLVLLGAPFLGATWGFPDDRVLPETASARQIGDELRQ
Mvan_4573|M.vanbaalenii_PYR-1       MRRSIPIGVVVVTLLLLLGAPFLGANWGFPDDRVLPQSASARQVGDELRT
MSMEG_5178|M.smegmatis_MC2_155      MRRAVPIGVGIIALLVLLGVPFTGIKWGFPDDRVLPQSASARQIGDEMRT
TH_1538|M.thermoresistible__bu      MRHWLVAGLAVTVVLLLLGAPFLGVRWGFPDERVLPRSASAHQVGHELRT
MAB_1287|M.abscessus_ATCC_1997      MARAVPIAIIIVSALVVLGLPFLDGKFGFPDDRVLPASASAHQVGNEMRR
MLBr_02620|M.leprae_Br4923          MKRPLVFAIPIVIGMILLVIPLGNLSFGGMSEKYLPPNNAVRQSQEHFDQ
                                    : : :  .  :   :::*  *: .  :*  .:: ** . : :*  . :  

Mb1177|M.bovis_AF2122/97            DFGHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVD
Rv1146|M.tuberculosis_H37Rv         DFGHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVD
MMAR_4305|M.marinum_M               NFAHDLAMAVPVVVPDVRGLVPADLDGYAADLSRVPDVASVTAPSGTFVN
MUL_0989|M.ulcerans_Agy99           NFAHDLAMAVPVVVPDVHGLVPADLDGYAADLSRVPDVASVTAPSGTFVN
MAV_1659|M.avium_104                DFPG-LGTELSVVVPDARGVTPAELRKYAAELSRVPDVSAVSAPTGTFSA
Mflv_2131|M.gilvum_PYR-GCK          DFAVDSSTNVVVVLPDADGISREDFDAYAIALSGVADVSSVSAPSGTFIG
Mvan_4573|M.vanbaalenii_PYR-1       DFAVDSSANVVVVLPDAEGLGPDALDGYAAELSRVQDVSSVSAPGGTFVD
MSMEG_5178|M.smegmatis_MC2_155      NFAVDSATSVTVVLPDATTVAPAEIDRYAARLSQVADVSSVSAPGGTDVQ
TH_1538|M.thermoresistible__bu      NFATDSASDVTVVLPDAPGLTADELAGYAARLSEVTDVAWVSAPAGTFVR
MAB_1287|M.abscessus_ATCC_1997      NFNNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIR
MLBr_02620|M.leprae_Br4923          LFPGYRTNPLTLVIQTSN-HQPVTDQEIADIRSKAMAISGFIEPDNNYVN
                                     *       : ::               *   *    :  .  * .    

Mb1177|M.bovis_AF2122/97            GSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRS
Rv1146|M.tuberculosis_H37Rv         GSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRS
MMAR_4305|M.marinum_M               GSRVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRT
MUL_0989|M.ulcerans_Agy99           GSRVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRT
MAV_1659|M.avium_104                GHRVGPPAAATGLANGSAFFTVSSTAPLYSPASNAQLDRLHQVAGPGGRA
Mflv_2131|M.gilvum_PYR-GCK          GARAGPPSAATGSADGSAFLTIGSRAPLFTDASEVQLDRLHAIAPPGDRQ
Mvan_4573|M.vanbaalenii_PYR-1       GAKAGPPSAATGIAEGSAFLTIGSTAPLFTDASETQLDRLHDVAPPEGRD
MSMEG_5178|M.smegmatis_MC2_155      GRHVGPPSAATGIGDGSAFLTVGSDAPLFSDASEAQLDALHAVAAH--AE
TH_1538|M.thermoresistible__bu      GRSVGPPSAPTGIADGSAFVTVGSVAPLFSDDSLEQLNDIRAVPAPGGTA
MAB_1287|M.abscessus_ATCC_1997      GMKVGPSASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVL
MLBr_02620|M.leprae_Br4923          ---MWQERTVAPGASKDPSVRVLQNGLINPNDASKKINELRSITPPKGLT
                                              :   .  . . :   .   .  :  ::. :: :.      

Mb1177|M.bovis_AF2122/97            VVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKAL
Rv1146|M.tuberculosis_H37Rv         VVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKAL
MMAR_4305|M.marinum_M               VEMAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKAL
MUL_0989|M.ulcerans_Agy99           VEMAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKAL
MAV_1659|M.avium_104                VQMTGLAQINRDSVEAITKRLPTVFGLIAVVTFMLLFLLTGSAVLPVQAL
Mflv_2131|M.gilvum_PYR-GCK          VLLTGLAQINRDSADAITSRLPLVLAVIAAITFVLLFVLTGSVVLPLKAL
Mvan_4573|M.vanbaalenii_PYR-1       VLLTGLAQINRDSADAITSRLPTVLAVIAAITFVLLFLLTGSVVLPLKAL
MSMEG_5178|M.smegmatis_MC2_155      VQFTGVAQVNRDSSQAITSRLPLVLGIIAGITFVLLFLLTGSVVLPLKAL
TH_1538|M.thermoresistible__bu      VQLTGTAQINHDIVVAVTSRLTVVLTVIALTTLVWLFLLTGSIVLPIKAL
MAB_1287|M.abscessus_ATCC_1997      VRIGGGAQLDRDAVDGIVHKLPLVLAIIAVVTFVLLFLLTGSVVLPIKAL
MLBr_02620|M.leprae_Br4923          VSVGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAFGSFVLPIKAA
                                    * . * . :::*   .:. : . :. ::   * : :*:  ** *** :* 

Mb1177|M.bovis_AF2122/97            VCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLS
Rv1146|M.tuberculosis_H37Rv         VCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLS
MMAR_4305|M.marinum_M               ICNVLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLS
MUL_0989|M.ulcerans_Agy99           ICNVLSLTAAFGALVWIFQDGHLGALGTIPSGTLVANMPVLLFCIAFGLS
MAV_1659|M.avium_104                VCNVLSLTAAFGAMVWIFQDGHLGALGTTPNGTLNANIPVLLFCIAFGLA
Mflv_2131|M.gilvum_PYR-GCK          VLNVLSLTAAFGALVWIFQEGHLGALGTTPTGTLVATMPVLLFCIAFGLS
Mvan_4573|M.vanbaalenii_PYR-1       VLNVLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANMPVLLFCIAFGLS
MSMEG_5178|M.smegmatis_MC2_155      VLNVLSLSAAFGALVWIFQDGHLGALGTTPTGTLVANLPVLLFCIAFGLS
TH_1538|M.thermoresistible__bu      VLNALSLTAAFGALVWIFQDGHLGALGTTPSGTMAVTMPALLLCVAFGIS
MAB_1287|M.abscessus_ATCC_1997      VLNVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMPMLLFCIAFGLS
MLBr_02620|M.leprae_Br4923          VMSALTLGSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIALVVAVGYGLA
                                    : ..*:* :::* : *** :**:.   .    .: . :  *:..:.:*::

Mb1177|M.bovis_AF2122/97            MDYEVFLVSRIREYWLESGAARPARRS------VAEVHAANDESVALGVA
Rv1146|M.tuberculosis_H37Rv         MDYEVFLVSRIREYWLESGAARPARRS------VAEVHAANDESVALGVA
MMAR_4305|M.marinum_M               MDYEVFLVARIREYWLASGAARPATPS------PAQAHAANDESVALGLA
MUL_0989|M.ulcerans_Agy99           MDYEVFLVARIREYWLASGAAGPATPS------PAQAHAANDESVALGLA
MAV_1659|M.avium_104                MDYEVFLVSRIHEYWLASQSIRETPPT------AREARAETDESTALGIA
Mflv_2131|M.gilvum_PYR-GCK          MDYEVFLVSRIREYWLETG--------------------ENGRSVALGLA
Mvan_4573|M.vanbaalenii_PYR-1       MDYEVFLVSRIREYWLASGGAGADSSTAHQRSDDLAPHVRSDESVALGLA
MSMEG_5178|M.smegmatis_MC2_155      MDYEVFLVSRIREFWLQSDQS----------------RAANEESVALGLA
TH_1538|M.thermoresistible__bu      MDYEVFLIARIREHWLASSRT----------------AAANDEAVALGVA
MAB_1287|M.abscessus_ATCC_1997      MDYEVFLISRIREYWMASGRT----------------RADNDEAVALGVA
MLBr_02620|M.leprae_Br4923          TDYEVFLVSRMVEARAESMST--------------------QEAVRIGTA
                                     ******::*: *    :                        .:. :* *

Mb1177|M.bovis_AF2122/97            RTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVV
Rv1146|M.tuberculosis_H37Rv         RTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVV
MMAR_4305|M.marinum_M               RTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVL
MUL_0989|M.ulcerans_Agy99           RTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAMAADATLVRMVL
MAV_1659|M.avium_104                GIGRVVTTAAVVMSISFAALIPAHVSFMRMLGLGLTLGVLVDATLVRMVL
Mflv_2131|M.gilvum_PYR-GCK          RTGRVVTAAALVMSISFAALIAAQVSFMRMFGGGLTLAVLVDATLVRMLL
Mvan_4573|M.vanbaalenii_PYR-1       RTGRVVTAAALLMSISFAALIAAKVAFMRMFGVGLTLAILADATLVRMLL
MSMEG_5178|M.smegmatis_MC2_155      HTGRVITAAALLMSISFAALIAAQVAFMRMFGLGLTLAVLVDATLVRMLL
TH_1538|M.thermoresistible__bu      RTARVITAAALIMSISFAALIGAQVSFMRMIGLGLMVAVLVDATLVRLIL
MAB_1287|M.abscessus_ATCC_1997      RTGRVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLL
MLBr_02620|M.leprae_Br4923          STGRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVRMFL
                                      .*::*:**:::::  .::: :.: :*: :. **  .:  ***::*:.:

Mb1177|M.bovis_AF2122/97            VPAFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAG
Rv1146|M.tuberculosis_H37Rv         VPAFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAG
MMAR_4305|M.marinum_M               VPAFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGDADAAAT----EAAD
MUL_0989|M.ulcerans_Agy99           VPAFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGGADAAAT----EAAD
MAV_1659|M.avium_104                VPAFIHLLGRWTWWAPRPMVWLRERSATGEAGEVRVGRRRWAR---DAPR
Mflv_2131|M.gilvum_PYR-GCK          VPAFMHLLGRWNWWAPPPLARLHARIGVSETVP-----------------
Mvan_4573|M.vanbaalenii_PYR-1       VPAFMHVLGRWNWWAPKPLARLHERIGFSETLDDSSDSPPRSR-------
MSMEG_5178|M.smegmatis_MC2_155      VPAFMRVMGRWNWWAPAPLARLHERIGFSESGLPPDPKP-----------
TH_1538|M.thermoresistible__bu      VPAFMHVMGRANWWAPAPLARWHDRFGIREAADAPDRPRSDPAPTPXXXD
MAB_1287|M.abscessus_ATCC_1997      VPSFMRLLGRFNWWAPKPLVTLHERIGFSD--------------------
MLBr_02620|M.leprae_Br4923          VPSVMKLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRPTVSGRPVRPP
                                    **:.::: *   ****      : * .  :                    

Mb1177|M.bovis_AF2122/97            RSDGQTIPASLTRNG-----------------------------------
Rv1146|M.tuberculosis_H37Rv         RSDGQTIPASLTRNG-----------------------------------
MMAR_4305|M.marinum_M               RRDRPTIPAALSGRG-----------------------------------
MUL_0989|M.ulcerans_Agy99           RRDRPTIPAALSGRG-----------------------------------
MAV_1659|M.avium_104                PAIRRWPSRATSGRG-----------------------------------
Mflv_2131|M.gilvum_PYR-GCK          ----QRV-------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       ----QHVATGNEHG------------------------------------
MSMEG_5178|M.smegmatis_MC2_155      ----QPASVGMTQSG-----------------------------------
TH_1538|M.thermoresistible__bu      ASVRKGPAPSSISRDPAVPAYVPDRPRTRSACRCSR--------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          VTAASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQIKRPQELPSGAS
                                                                                      

Mb1177|M.bovis_AF2122/97            --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               --------------------------------------------------
MUL_0989|M.ulcerans_Agy99           --------------------------------------------------
MAV_1659|M.avium_104                --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155      --------------------------------------------------
TH_1538|M.thermoresistible__bu      --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          TARIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQAVPLAATRHPLP
                                                                                      

Mb1177|M.bovis_AF2122/97            --------------------------------------------------
Rv1146|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4305|M.marinum_M               --------------------------------------------------
MUL_0989|M.ulcerans_Agy99           --------------------------------------------------
MAV_1659|M.avium_104                --------------------------------------------------
Mflv_2131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5178|M.smegmatis_MC2_155      --------------------------------------------------
TH_1538|M.thermoresistible__bu      --------------------------------------------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02620|M.leprae_Br4923          TPSPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQDNDSEVATEKL
                                                                                      

Mb1177|M.bovis_AF2122/97            --------------------------------
Rv1146|M.tuberculosis_H37Rv         --------------------------------
MMAR_4305|M.marinum_M               --------------------------------
MUL_0989|M.ulcerans_Agy99           --------------------------------
MAV_1659|M.avium_104                --------------------------------
Mflv_2131|M.gilvum_PYR-GCK          --------------------------------
Mvan_4573|M.vanbaalenii_PYR-1       --------------------------------
MSMEG_5178|M.smegmatis_MC2_155      --------------------------------
TH_1538|M.thermoresistible__bu      --------------------------------
MAB_1287|M.abscessus_ATCC_1997      --------------------------------
MLBr_02620|M.leprae_Br4923          NALGQGDNSRQHRRATGGGISAQDLLRREGRL