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VMAMLRVITRLAIAAPRRIIGIAVLVMVGAAIFGLPVVNSLSGGGFQDPTSESARATEILRDRFNQTDQQ MLIVVSAPDGARSPQAHRVGTDIVDKLKNSPWVMSVSSAWTSPPAAAAQLISKDNKSGMIVAGLKGGEND AQKYASTLTRELVHDRDGVTVRAGGMAVAYAQINAQNQRDLLLMESIAIPLSFAVLVWVLGGVVAATLPV VLGALAIVGTMSVLRLISFATDVSTYALDLSIAMGLALAIDYNLLIITRYREELARTEDRDRALYRTMAT AGRTVLFSATTVGLSMAVMAVFPMYFLKSSAYTIVATAIIVAIAAVVITPAAIVLLGPRLDTMDARRVMH RILHGQRSFRDPAHKPLVEQFWYRSTKYVLRRAVPVGLSVVALLLLLGVPFLGVKWGFPDERVLPRSASA RQVADMLDNDFPGLGTELSVVVPDARGVTPAELRKYAAELSRVPDVSAVSAPTGTFSAGHRVGPPAAATG LANGSAFFTVSSTAPLYSPASNAQLDRLHQVAGPGGRAVQMTGLAQINRDSVEAITKRLPTVFGLIAVVT FMLLFLLTGSAVLPVQALVCNVLSLTAAFGAMVWIFQDGHLGALGTTPNGTLNANIPVLLFCIAFGLAMD YEVFLVSRIHEYWLASQSIRETPPTAREARAETDESTALGIAGIGRVVTTAAVVMSISFAALIPAHVSFM RMLGLGLTLGVLVDATLVRMVLVPAFIHLLGRWTWWAPRPMVWLRERSATGEAGEVRVGRRRWARDAPRP AIRRWPSRATSGRG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_1659 | - | - | 100% (784) | mmpl family protein |
M. avium 104 | MAV_1287 | - | 0.0 | 64.24% (797) | mmpL protein |
M. avium 104 | MAV_4968 | - | 8e-85 | 28.64% (789) | MmpL3 protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1177 | mmpL13 | 0.0 | 68.16% (760) | transmembrane transport protein MmpL13 |
M. gilvum PYR-GCK | Mflv_2131 | - | 0.0 | 62.43% (756) | MMPL domain-containing protein |
M. tuberculosis H37Rv | Rv1146 | mmpL13b | 1e-173 | 69.04% (449) | transmembrane transport protein MmpL13B |
M. leprae Br4923 | MLBr_02620 | - | 6e-88 | 28.89% (758) | hypothetical protein MLBr_02620 |
M. abscessus ATCC 19977 | MAB_1287 | - | 0.0 | 54.09% (745) | MmpL family membrane protein |
M. marinum M | MMAR_4305 | mmpL13 | 0.0 | 65.10% (788) | transmembrane transport protein MmpL13 |
M. smegmatis MC2 155 | MSMEG_5178 | - | 0.0 | 61.99% (755) | integral membrane protein |
M. thermoresistible (build 8) | TH_1538 | - | 0.0 | 54.33% (786) | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13B |
M. ulcerans Agy99 | MUL_0989 | mmpL13 | 0.0 | 64.59% (788) | transmembrane transport protein MmpL13 |
M. vanbaalenii PYR-1 | Mvan_4573 | - | 0.0 | 64.16% (759) | MMPL domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb1177|M.bovis_AF2122/97 ---MLQRIARLAIAAPRRIIGFAVFVFIAAAVFGVPVADSLSPGGFQDPR Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4305|M.marinum_M ---MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSPGGFQDPN MUL_0989|M.ulcerans_Agy99 ---MLQGIARLAIAAPRRIIGVALLVFIAAAVFGIPVANSLSRGGFQDPN MAV_1659|M.avium_104 MMAMLRVITRLAIAAPRRIIGIAVLVMVGAAIFGLPVVNSLSGGGFQDPT Mflv_2131|M.gilvum_PYR-GCK ---MLHRIARLAIAAPRRVLMAALLVAIACGVFGIPVVTHLSAGGFQDPT Mvan_4573|M.vanbaalenii_PYR-1 ---MLHRIALLAIAAPRRVLVVALLIMVGCGIFGAPVAKHLSAGGFQDPT MSMEG_5178|M.smegmatis_MC2_155 ---MLQRIATTAIAAPRRILVVAALVMIAAGIFGIPVANKLSAGGFQDPT TH_1538|M.thermoresistible__bu ---MLETLARRIVAAPRRVLALVVLVIVGAAMFGLPVAGSLSAGGFRDPH MAB_1287|M.abscessus_ATCC_1997 --MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPN MLBr_02620|M.leprae_Br4923 ---MFAWWGRTVYRYRFIVIGITVALCLCGGVFGLSLGKHVTQSGFYDDS Mb1177|M.bovis_AF2122/97 SESARAIEVLTDKFGQSGQKMLIVVTAA---AGADSPPAREVGTDIVEVL Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4305|M.marinum_M AESARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAEL MUL_0989|M.ulcerans_Agy99 AESARAIKVLADKFGQSGQQMLILVTAP---GGVGTERARAVGTDIVAEL MAV_1659|M.avium_104 SESARATEILRDRFNQTDQQMLIVVSAP---DGARSPQAHRVGTDIVDKL Mflv_2131|M.gilvum_PYR-GCK SESARATQMLVDTFGQGDMELILAVTSD---DGAQSPAARDVGVELVERL Mvan_4573|M.vanbaalenii_PYR-1 SESARATQLLVDKFDQGDMELLISITDDNSADGANSPAARAVGTDLADRL MSMEG_5178|M.smegmatis_MC2_155 AESARATQLLADKFHRGDMQLVIAVTAEAPGGRADGGRAREVGTEIVSEL TH_1538|M.thermoresistible__bu SESAQASALLAERFDQTDMQLLVTVSSS---AGVYGEAARRVGTEIVAAL MAB_1287|M.abscessus_ATCC_1997 SESAYVTKALRDKFDISDQSLVFMLTSE---QGVKSPQMRAVAADLERQL MLBr_02620|M.leprae_Br4923 SQSVKASILGDQVYGRDRSGHIVAIFHAPDGKTVNDPAWAKKITDELNQF Mb1177|M.bovis_AF2122/97 R--RSPLVYNVTSPWTVP---PTAAADLLSTDGKSGLIVVNVKGGENDAQ Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4305|M.marinum_M N--HSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQ MUL_0989|M.ulcerans_Agy99 N--HSPLVFNVSSPWTGPSADPKSAPDLVSKDGKSGLIVVNIKGGESNAQ MAV_1659|M.avium_104 K--NSPWVMSVSSAWTSP---PAAAAQLISKDNKSGMIVAGLKGGENDAQ Mflv_2131|M.gilvum_PYR-GCK S--DSPHVAAITSAWTSP---PSAAPALISEDGRTGLIVAGITGGESGAQ Mvan_4573|M.vanbaalenii_PYR-1 A--ASPHVGAVTSAWTAP---PSAAPALVSEDGRTGLIIAGITGGESEAQ MSMEG_5178|M.smegmatis_MC2_155 K--ASPYVTEVTSAWTAP---PSAAAALVSKDARTGLIVAGLNGGENGAQ TH_1538|M.thermoresistible__bu E--ASPQVAGVQSPWTVP---PGAGDRLVSEDATAGLIVAPIRGNETESS MAB_1287|M.abscessus_ATCC_1997 K--DSGVVINLTSAWTAP---PQVAEELLGADGKAGLIVAGLTGGENDAQ MLBr_02620|M.leprae_Br4923 QRNNSNKVTGWAGYLRASDTTNTVVQGMATPDKKYTFVSIPLKGDDDDTI Mb1177|M.bovis_AF2122/97 NHAQTLSDEVAHDRDGVTVRAGGSAMEYAQINRQNKDDLLVMELIAIPLS Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4305|M.marinum_M KNAQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLS MUL_0989|M.ulcerans_Agy99 KNAQTLADEIVHDRDGVTVRAGGSAMEYAQINKQNQDDLLVMELIAIPLS MAV_1659|M.avium_104 KYASTLTRELVHDRDGVTVRAGGMAVAYAQINAQNQRDLLLMESIAIPLS Mflv_2131|M.gilvum_PYR-GCK KLAKALTDELVYDRDGVTVRAGGAAMTYVQINTQTEKDLLLMESIAIPLS Mvan_4573|M.vanbaalenii_PYR-1 KHAKTLTDELVRDRDGVTVRAGGVAMTYVQINTQSEKDLLMMESIAIPLS MSMEG_5178|M.smegmatis_MC2_155 QHAKELTDQFVRDHDGVRVRAGGEAMIYVQINGQSEKDLLMMESIAIPLS TH_1538|M.thermoresistible__bu DIARQLAAAVGSDRDRVNVRAGGPALVNAQIDTQTEHDLLVMEAIAIPLS MAB_1287|M.abscessus_ATCC_1997 KHAAKLIKSLAVDRDGVAVKAGGVATLYNQIVTQSEKDLLVMESIAIPIS MLBr_02620|M.leprae_Br4923 LNNYKAIAPDLQKLDGGTVQLAGLDPIANALTSTIATDQRRMEVLALPLV Mb1177|M.bovis_AF2122/97 FLVLIWVFGGLLAAGLPMAQAVLAVVGSMAVLRLVTFATEVSTFALNLST Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4305|M.marinum_M FLVLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLST MUL_0989|M.ulcerans_Agy99 FLVLVWVFGGLLAAALPMALGALAVVGSMSVLRLVTFTTDVSIFALNLST MAV_1659|M.avium_104 FAVLVWVLGGVVAATLPVVLGALAIVGTMSVLRLISFATDVSTYALDLSI Mflv_2131|M.gilvum_PYR-GCK FVVLVWVFGGLLAAALPLAVGVFAILGSMAVLRGFTLVTDVSIFALNLSI Mvan_4573|M.vanbaalenii_PYR-1 FVVLVWVFGGLLAAALPLAVGAFAILGSMAVLRAVTLVTDVSIFALNLSI MSMEG_5178|M.smegmatis_MC2_155 FVVLVWVFGGLLAAALPLAVGGFAILGSLAVLRLFTMVTDVSIFALNLTV TH_1538|M.thermoresistible__bu FVVLVWVFGGLLAAALPLAVGVLAIVGSMAVLRTFTMFTEVSVFALNLSI MAB_1287|M.abscessus_ATCC_1997 FVVLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAV MLBr_02620|M.leprae_Br4923 AVVLFLVFGGVIAACLPVMVGGLSIAGALGILRFIALFGPVHFFAQPVVS Mb1177|M.bovis_AF2122/97 ALGLALAIDYTLLIVSRYRDELAEGSDRDEALIRTMATSGRTVLFSAVTV Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4305|M.marinum_M ALGLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTV MUL_0989|M.ulcerans_Agy99 ALGLALAIDYTLLIISRYRDELAEGSSREEALVRTMATSGRTVLFSAVTV MAV_1659|M.avium_104 AMGLALAIDYNLLIITRYREELARTEDRDRALYRTMATAGRTVLFSATTV Mflv_2131|M.gilvum_PYR-GCK AMGLALAIDYTLLIISRYRDELADGHDRDTALLRTMTTAGRTVVFSATTV Mvan_4573|M.vanbaalenii_PYR-1 AMGLALAIDYTLLIISRYRDELAEGHDRDSALVRTMMTAGRTVLFSALTV MSMEG_5178|M.smegmatis_MC2_155 AMGLALAIDYTLLIISRFRDELAEGADRETALVRTMMTAGRTVLFSAMTV TH_1538|M.thermoresistible__bu AMGLALAIDYTLLLLNRYRDELAEGCSREQAVIRTMTSAGRTVIFSAVIV MAB_1287|M.abscessus_ATCC_1997 AMGLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTV MLBr_02620|M.leprae_Br4923 LIGLGIAVDYGLFVVSRFREEIAEGYDTEAAVRRTVMTAGRTVTFSAVLI Mb1177|M.bovis_AF2122/97 ALSMSATALFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGPRLDA Rv1146|M.tuberculosis_H37Rv ----------------------MATVAFVATASIVITPAAIVLLGPRLDA MMAR_4305|M.marinum_M ALSMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDA MUL_0989|M.ulcerans_Agy99 ALSMSATVAFPMYFLKSFAYAGVATVAFVATASIVVTPAAIVLLGPRLDA MAV_1659|M.avium_104 GLSMAVMAVFPMYFLKSSAYTIVATAIIVAIAAVVITPAAIVLLGPRLDT Mflv_2131|M.gilvum_PYR-GCK ALSMVAMVLFPMYFLKSFAYAGIAVVSFAALAAIVVTPAAIALAGDRLDA Mvan_4573|M.vanbaalenii_PYR-1 ALSMVAMVLFPMYFLKSFAYAGIAVVGFAAVAAIVVAPAAIVLAGARLDS MSMEG_5178|M.smegmatis_MC2_155 ALSMVAMVLFPMYFLKSFAYAGIAVVALAATAAIVLTPAAIVLLGDRLDA TH_1538|M.thermoresistible__bu ATSMVPLALFPMYFLRSFAYAGVGVVAFALCAALVITPAAITVLGARLDS MAB_1287|M.abscessus_ATCC_1997 ALALVALILFPMYFLKSFGYAGVAVVFVGAIAALVIVPAVVTLLGDRIDA MLBr_02620|M.leprae_Br4923 AASGASLLLLPQGFVKSLTYALIAAVTLAALLSITLLPACLAILAKHVDA :... . ::.: ** :.: . ::*: Mb1177|M.bovis_AF2122/97 LDVRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFV Rv1146|M.tuberculosis_H37Rv LDVRRLVRRLLGRP-----------------DPVHKPVKQLFWYRSSKFV MMAR_4305|M.marinum_M LNVRRLARRMLGRP-----------------EPQHKPVDQLFWYRSTKFV MUL_0989|M.ulcerans_Agy99 LNVRRLARRMLGRP-----------------KPQHKPVDQLFWYRSTKFV MAV_1659|M.avium_104 MDARRVMHRILHGQR-------------SFRDPAHKPLVEQFWYRSTKYV Mflv_2131|M.gilvum_PYR-GCK LDVRRLVRRILGRP-----------------DPVAKPVEQNFWYRSTTFV Mvan_4573|M.vanbaalenii_PYR-1 MDVRRLVRRVLGRP-----------------EPVAKPVEQMFWYRSTKFV MSMEG_5178|M.smegmatis_MC2_155 YDVRRFFRRVFGRP-----------------EPEPKPVEQGFWYRTAKAA TH_1538|M.thermoresistible__bu WDIRRLIRRLMRRTP-------------AAAEPAPRAVCGSKWYRWAKAV MAB_1287|M.abscessus_ATCC_1997 LDVRRLIRRVLGRP-----------------EPVAKDVTQSFWYRTTKRV MLBr_02620|M.leprae_Br4923 LGVRTLFRVPLLRNWRMSHACLNWLADRLQKTKTREEVEAGFWGKLVNFV . * . : : . : * : . . Mb1177|M.bovis_AF2122/97 MRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRD Rv1146|M.tuberculosis_H37Rv MRRWLPVGTAVVALLVLLGLPFLSVKWGFPDDRVLPRSASARQVGDILRD MMAR_4305|M.marinum_M MRRALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRT MUL_0989|M.ulcerans_Agy99 MRRALPVGLAVVAVLVILGLPFFSVKWGFPDDRVLPATASSHQVGDELRT MAV_1659|M.avium_104 LRRAVPVGLSVVALLLLLGVPFLGVKWGFPDERVLPRSASARQVADMLDN Mflv_2131|M.gilvum_PYR-GCK MRRSIPIGGVVVVLLVLLGAPFLGATWGFPDDRVLPETASARQIGDELRQ Mvan_4573|M.vanbaalenii_PYR-1 MRRSIPIGVVVVTLLLLLGAPFLGANWGFPDDRVLPQSASARQVGDELRT MSMEG_5178|M.smegmatis_MC2_155 MRRAVPIGVGIIALLVLLGVPFTGIKWGFPDDRVLPQSASARQIGDEMRT TH_1538|M.thermoresistible__bu MRHWLVAGLAVTVVLLLLGAPFLGVRWGFPDERVLPRSASAHQVGHELRT MAB_1287|M.abscessus_ATCC_1997 MARAVPIAIIIVSALVVLGLPFLDGKFGFPDDRVLPASASAHQVGNEMRR MLBr_02620|M.leprae_Br4923 MKRPLVFAIPIVIGMILLVIPLGNLSFGGMSEKYLPPNNAVRQSQEHFDQ : : : . : :::* *: . :* .:: ** . : :* . : Mb1177|M.bovis_AF2122/97 DFGHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVD Rv1146|M.tuberculosis_H37Rv DFGHDPATQIPIVVPDARGLGPVELDSYAAELSRVPDVSAVAAPTGTFVD MMAR_4305|M.marinum_M NFAHDLAMAVPVVVPDVRGLVPADLDGYAADLSRVPDVASVTAPSGTFVN MUL_0989|M.ulcerans_Agy99 NFAHDLAMAVPVVVPDVHGLVPADLDGYAADLSRVPDVASVTAPSGTFVN MAV_1659|M.avium_104 DFPG-LGTELSVVVPDARGVTPAELRKYAAELSRVPDVSAVSAPTGTFSA Mflv_2131|M.gilvum_PYR-GCK DFAVDSSTNVVVVLPDADGISREDFDAYAIALSGVADVSSVSAPSGTFIG Mvan_4573|M.vanbaalenii_PYR-1 DFAVDSSANVVVVLPDAEGLGPDALDGYAAELSRVQDVSSVSAPGGTFVD MSMEG_5178|M.smegmatis_MC2_155 NFAVDSATSVTVVLPDATTVAPAEIDRYAARLSQVADVSSVSAPGGTDVQ TH_1538|M.thermoresistible__bu NFATDSASDVTVVLPDAPGLTADELAGYAARLSEVTDVAWVSAPAGTFVR MAB_1287|M.abscessus_ATCC_1997 NFNNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIR MLBr_02620|M.leprae_Br4923 LFPGYRTNPLTLVIQTSN-HQPVTDQEIADIRSKAMAISGFIEPDNNYVN * : :: * * : . * . Mb1177|M.bovis_AF2122/97 GSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRS Rv1146|M.tuberculosis_H37Rv GSWVGTPRGATGLAEGSAFLTVSSTAPLFSRASDIQLKRLHQVAGPAGRS MMAR_4305|M.marinum_M GSRVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRT MUL_0989|M.ulcerans_Agy99 GSRVGPPAGATGFSDGSAFLTVDSTAPLFSHASDIQLKRLHQVTGPAGRT MAV_1659|M.avium_104 GHRVGPPAAATGLANGSAFFTVSSTAPLYSPASNAQLDRLHQVAGPGGRA Mflv_2131|M.gilvum_PYR-GCK GARAGPPSAATGSADGSAFLTIGSRAPLFTDASEVQLDRLHAIAPPGDRQ Mvan_4573|M.vanbaalenii_PYR-1 GAKAGPPSAATGIAEGSAFLTIGSTAPLFTDASETQLDRLHDVAPPEGRD MSMEG_5178|M.smegmatis_MC2_155 GRHVGPPSAATGIGDGSAFLTVGSDAPLFSDASEAQLDALHAVAAH--AE TH_1538|M.thermoresistible__bu GRSVGPPSAPTGIADGSAFVTVGSVAPLFSDDSLEQLNDIRAVPAPGGTA MAB_1287|M.abscessus_ATCC_1997 GMKVGPSASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVL MLBr_02620|M.leprae_Br4923 ---MWQERTVAPGASKDPSVRVLQNGLINPNDASKKINELRSITPPKGLT : . . . : . . : ::. :: :. Mb1177|M.bovis_AF2122/97 VVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKAL Rv1146|M.tuberculosis_H37Rv VVMAGVAQVNRDSVDAVTDRLPMVLGLIAAITYVLLFLLTGSVVLPAKAL MMAR_4305|M.marinum_M VEMAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKAL MUL_0989|M.ulcerans_Agy99 VEMAGVAQVNRDSVDAVTERLPLVLGLMAAITFVLLFLLTGSVVLPAKAL MAV_1659|M.avium_104 VQMTGLAQINRDSVEAITKRLPTVFGLIAVVTFMLLFLLTGSAVLPVQAL Mflv_2131|M.gilvum_PYR-GCK VLLTGLAQINRDSADAITSRLPLVLAVIAAITFVLLFVLTGSVVLPLKAL Mvan_4573|M.vanbaalenii_PYR-1 VLLTGLAQINRDSADAITSRLPTVLAVIAAITFVLLFLLTGSVVLPLKAL MSMEG_5178|M.smegmatis_MC2_155 VQFTGVAQVNRDSSQAITSRLPLVLGIIAGITFVLLFLLTGSVVLPLKAL TH_1538|M.thermoresistible__bu VQLTGTAQINHDIVVAVTSRLTVVLTVIALTTLVWLFLLTGSIVLPIKAL MAB_1287|M.abscessus_ATCC_1997 VRIGGGAQLDRDAVDGIVHKLPLVLAIIAVVTFVLLFLLTGSVVLPIKAL MLBr_02620|M.leprae_Br4923 VSVGGTPALEQDSIHSLVAQAPLMVIMLITTTMLLMFLAFGSFVLPIKAA * . * . :::* .:. : . :. :: * : :*: ** *** :* Mb1177|M.bovis_AF2122/97 VCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLS Rv1146|M.tuberculosis_H37Rv VCNVLSLTAAFGALVWIFQEGHFGALGTTPSGTLVANMPVLLFCIAFGLS MMAR_4305|M.marinum_M ICNVLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLS MUL_0989|M.ulcerans_Agy99 ICNVLSLTAAFGALVWIFQDGHLGALGTIPSGTLVANMPVLLFCIAFGLS MAV_1659|M.avium_104 VCNVLSLTAAFGAMVWIFQDGHLGALGTTPNGTLNANIPVLLFCIAFGLA Mflv_2131|M.gilvum_PYR-GCK VLNVLSLTAAFGALVWIFQEGHLGALGTTPTGTLVATMPVLLFCIAFGLS Mvan_4573|M.vanbaalenii_PYR-1 VLNVLSLTAAFGALVWIFQDGHLGALGTTPTGTLVANMPVLLFCIAFGLS MSMEG_5178|M.smegmatis_MC2_155 VLNVLSLSAAFGALVWIFQDGHLGALGTTPTGTLVANLPVLLFCIAFGLS TH_1538|M.thermoresistible__bu VLNALSLTAAFGALVWIFQDGHLGALGTTPSGTMAVTMPALLLCVAFGIS MAB_1287|M.abscessus_ATCC_1997 VLNVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMPMLLFCIAFGLS MLBr_02620|M.leprae_Br4923 VMSALTLGSTMGILTWIFVDGHLSKWLNFTPTPLMVVIIALVVAVGYGLA : ..*:* :::* : *** :**:. . .: . : *:..:.:*:: Mb1177|M.bovis_AF2122/97 MDYEVFLVSRIREYWLESGAARPARRS------VAEVHAANDESVALGVA Rv1146|M.tuberculosis_H37Rv MDYEVFLVSRIREYWLESGAARPARRS------VAEVHAANDESVALGVA MMAR_4305|M.marinum_M MDYEVFLVARIREYWLASGAARPATPS------PAQAHAANDESVALGLA MUL_0989|M.ulcerans_Agy99 MDYEVFLVARIREYWLASGAAGPATPS------PAQAHAANDESVALGLA MAV_1659|M.avium_104 MDYEVFLVSRIHEYWLASQSIRETPPT------AREARAETDESTALGIA Mflv_2131|M.gilvum_PYR-GCK MDYEVFLVSRIREYWLETG--------------------ENGRSVALGLA Mvan_4573|M.vanbaalenii_PYR-1 MDYEVFLVSRIREYWLASGGAGADSSTAHQRSDDLAPHVRSDESVALGLA MSMEG_5178|M.smegmatis_MC2_155 MDYEVFLVSRIREFWLQSDQS----------------RAANEESVALGLA TH_1538|M.thermoresistible__bu MDYEVFLIARIREHWLASSRT----------------AAANDEAVALGVA MAB_1287|M.abscessus_ATCC_1997 MDYEVFLISRIREYWMASGRT----------------RADNDEAVALGVA MLBr_02620|M.leprae_Br4923 TDYEVFLVSRMVEARAESMST--------------------QEAVRIGTA ******::*: * : .:. :* * Mb1177|M.bovis_AF2122/97 RTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVV Rv1146|M.tuberculosis_H37Rv RTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVV MMAR_4305|M.marinum_M RTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVAADATLVRMVL MUL_0989|M.ulcerans_Agy99 RTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAMAADATLVRMVL MAV_1659|M.avium_104 GIGRVVTTAAVVMSISFAALIPAHVSFMRMLGLGLTLGVLVDATLVRMVL Mflv_2131|M.gilvum_PYR-GCK RTGRVVTAAALVMSISFAALIAAQVSFMRMFGGGLTLAVLVDATLVRMLL Mvan_4573|M.vanbaalenii_PYR-1 RTGRVVTAAALLMSISFAALIAAKVAFMRMFGVGLTLAILADATLVRMLL MSMEG_5178|M.smegmatis_MC2_155 HTGRVITAAALLMSISFAALIAAQVAFMRMFGLGLTLAVLVDATLVRMLL TH_1538|M.thermoresistible__bu RTARVITAAALIMSISFAALIGAQVSFMRMIGLGLMVAVLVDATLVRLIL MAB_1287|M.abscessus_ATCC_1997 RTGRVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLL MLBr_02620|M.leprae_Br4923 STGRLITAAALVLAVVAGSFVFSDLVMMKYLAFGLMAALLLDATVVRMFL .*::*:**::::: .::: :.: :*: :. ** .: ***::*:.: Mb1177|M.bovis_AF2122/97 VPAFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAG Rv1146|M.tuberculosis_H37Rv VPAFMHVTGRWNWWAPRPLAWLHERFGVSEAAEPVSRRRSHAGGLGKIAG MMAR_4305|M.marinum_M VPAFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGDADAAAT----EAAD MUL_0989|M.ulcerans_Agy99 VPAFMHVMGRWNWWAPKPLVWLHQRFGISETGAVGGADAAAT----EAAD MAV_1659|M.avium_104 VPAFIHLLGRWTWWAPRPMVWLRERSATGEAGEVRVGRRRWAR---DAPR Mflv_2131|M.gilvum_PYR-GCK VPAFMHLLGRWNWWAPPPLARLHARIGVSETVP----------------- Mvan_4573|M.vanbaalenii_PYR-1 VPAFMHVLGRWNWWAPKPLARLHERIGFSETLDDSSDSPPRSR------- MSMEG_5178|M.smegmatis_MC2_155 VPAFMRVMGRWNWWAPAPLARLHERIGFSESGLPPDPKP----------- TH_1538|M.thermoresistible__bu VPAFMHVMGRANWWAPAPLARWHDRFGIREAADAPDRPRSDPAPTPXXXD MAB_1287|M.abscessus_ATCC_1997 VPSFMRLLGRFNWWAPKPLVTLHERIGFSD-------------------- MLBr_02620|M.leprae_Br4923 VPSVMKLLGDDCWWAPRWARLLQNRIGLGEIHLPDERRRPTVSGRPVRPP **:.::: * **** : * . : Mb1177|M.bovis_AF2122/97 RSDGQTIPASLTRNG----------------------------------- Rv1146|M.tuberculosis_H37Rv RSDGQTIPASLTRNG----------------------------------- MMAR_4305|M.marinum_M RRDRPTIPAALSGRG----------------------------------- MUL_0989|M.ulcerans_Agy99 RRDRPTIPAALSGRG----------------------------------- MAV_1659|M.avium_104 PAIRRWPSRATSGRG----------------------------------- Mflv_2131|M.gilvum_PYR-GCK ----QRV------------------------------------------- Mvan_4573|M.vanbaalenii_PYR-1 ----QHVATGNEHG------------------------------------ MSMEG_5178|M.smegmatis_MC2_155 ----QPASVGMTQSG----------------------------------- TH_1538|M.thermoresistible__bu ASVRKGPAPSSISRDPAVPAYVPDRPRTRSACRCSR-------------- MAB_1287|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02620|M.leprae_Br4923 VTAASLAAPASRVPRGPTHPATLEPSQRARSGLASRPQIKRPQELPSGAS Mb1177|M.bovis_AF2122/97 -------------------------------------------------- Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4305|M.marinum_M -------------------------------------------------- MUL_0989|M.ulcerans_Agy99 -------------------------------------------------- MAV_1659|M.avium_104 -------------------------------------------------- Mflv_2131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4573|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5178|M.smegmatis_MC2_155 -------------------------------------------------- TH_1538|M.thermoresistible__bu -------------------------------------------------- MAB_1287|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02620|M.leprae_Br4923 TARIQMRPSQSVEATTTRLSVPGNAPTTAAVSSSQGVQAVPLAATRHPLP Mb1177|M.bovis_AF2122/97 -------------------------------------------------- Rv1146|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4305|M.marinum_M -------------------------------------------------- MUL_0989|M.ulcerans_Agy99 -------------------------------------------------- MAV_1659|M.avium_104 -------------------------------------------------- Mflv_2131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4573|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5178|M.smegmatis_MC2_155 -------------------------------------------------- TH_1538|M.thermoresistible__bu -------------------------------------------------- MAB_1287|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02620|M.leprae_Br4923 TPSPASGQTRAMPVPANRSSDNASETAEPTTALPIMRPQDNDSEVATEKL Mb1177|M.bovis_AF2122/97 -------------------------------- Rv1146|M.tuberculosis_H37Rv -------------------------------- MMAR_4305|M.marinum_M -------------------------------- MUL_0989|M.ulcerans_Agy99 -------------------------------- MAV_1659|M.avium_104 -------------------------------- Mflv_2131|M.gilvum_PYR-GCK -------------------------------- Mvan_4573|M.vanbaalenii_PYR-1 -------------------------------- MSMEG_5178|M.smegmatis_MC2_155 -------------------------------- TH_1538|M.thermoresistible__bu -------------------------------- MAB_1287|M.abscessus_ATCC_1997 -------------------------------- MLBr_02620|M.leprae_Br4923 NALGQGDNSRQHRRATGGGISAQDLLRREGRL