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TAPPGGPYGPGSYGSNPYGQEPNWSGQPPGGQPQGGQPQGGPYPQPGQYPAGGPYPYPPPGGGYPYPGGP YPGGPYPGAPYPGPGQPFGPGGPYSPGPPPGGPGSKLPWLIVAGLVVLAVIALVATLVVMKGGHGSKPSG ATPSSTSTSVSQPKNSAQNATDCTPNVSGGDMPRSDSIAAGKLSFPANAAPSGWTVFSDDQGPNLIGALG VAQDVPGANQWMMTAEVGVTNFVPSMDLTAQATKLMQCLANGPGYANAMPTLGPIKTSPITVDGTKAVRA DADVTIADPTRNVKGDSVTIIAVDTKPVSVFIGSTPIGDSASAGLIGKIIAALKVAKS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1219 | - | - | 100% (339) | hypothetical protein MAV_1219 |
| M. avium 104 | MAV_1372 | - | 2e-12 | 36.18% (152) | hypothetical protein MAV_1372 |
| M. avium 104 | MAV_3693 | infB | 8e-12 | 34.38% (128) | translation initiation factor IF-2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1127c | - | 1e-99 | 57.52% (339) | hypothetical protein Mb1127c |
| M. gilvum PYR-GCK | Mflv_2044 | - | 6e-13 | 36.73% (147) | integral membrane protein-like protein |
| M. tuberculosis H37Rv | Rv1097c | - | 1e-101 | 57.82% (339) | hypothetical protein Rv1097c |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 3e-11 | 40.91% (88) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_0039c | - | 3e-11 | 35.66% (143) | hypothetical protein MAB_0039c |
| M. marinum M | MMAR_4369 | - | 1e-111 | 60.12% (346) | membrane glycine and proline rich protein |
| M. smegmatis MC2 155 | MSMEG_5268 | - | 4e-16 | 46.15% (117) | hypothetical protein MSMEG_5268 |
| M. thermoresistible (build 8) | TH_3438 | - | 3e-13 | 31.25% (192) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0182 | - | 1e-111 | 60.12% (346) | membrane glycine and proline rich protein |
| M. vanbaalenii PYR-1 | Mvan_4673 | - | 5e-12 | 40.82% (147) | hypothetical protein Mvan_4673 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2044|M.gilvum_PYR-GCK ---------MTE-----NPPP--GGYPPPPQ--GGYPPPPPSEGGYPP--
Mvan_4673|M.vanbaalenii_PYR-1 ---------MTE-----NPPP--GGYPPPPP--GGYPPPPPP-GGYQP--
MSMEG_5268|M.smegmatis_MC2_155 ---------MTDQPPGNNPPPPDGGYPPPPPPDGGYPPPPPPDGGYPPAQ
Mb1127c|M.bovis_AF2122/97 -----------------MTVPPAGPYGNYPYGPNTYGQDLYWGGQPQGG-
Rv1097c|M.tuberculosis_H37Rv -----------------MTVPPAGPYGNYPYGPNTYGQDPYWGGQPQGG-
MMAR_4369|M.marinum_M -----------------MTTPPGGPYGQDPAGYNPYGQAPYGYGQPQAGG
MUL_0182|M.ulcerans_Agy99 -----------------MTTPPGGPYGQDPAGYNPYGQAPYGYGQPQAGG
MAV_1219|M.avium_104 -----------------MTAPPGGPYGPGSYGSNPYGQEPNWSGQPPGGQ
MLBr_02395|M.leprae_Br4923 ---------------MTDQPPPSGSNPTPAP------PPPGSSGGYEPS-
TH_3438|M.thermoresistible__bu -------VTNWTGGGDFGGPNPIGGDPSGGQPGGGWGAPPPPPTQWTPEQ
MAB_0039c|M.abscessus_ATCC_199 MGIVQRFERKLEDVVGDAFARVFGGSIVPQEVQASLRREAADGVRSAGQG
*
Mflv_2044|M.gilvum_PYR-GCK -------------------------------------------------P
Mvan_4673|M.vanbaalenii_PYR-1 -------------------------------------------------P
MSMEG_5268|M.smegmatis_MC2_155 PGGFG--------------------------------------------P
Mb1127c|M.bovis_AF2122/97 --------------------------------------------------
Rv1097c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4369|M.marinum_M QY------------------------------------------------
MUL_0182|M.ulcerans_Agy99 QY------------------------------------------------
MAV_1219|M.avium_104 PQG-----------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_3438|M.thermoresistible__bu PPQ-----------------------------------------------
MAB_0039c|M.abscessus_ATCC_199 RLLAPNEFFVLLSTADHEKAADDRDLNPDTFAELLREYIRDQGWQTYGEV
Mflv_2044|M.gilvum_PYR-GCK PPEGGYPPPPPAGGYQQ----PPPGGAYPPPPGPGGYPPPPGQ--GGYPP
Mvan_4673|M.vanbaalenii_PYR-1 PP------PPSGGGYP-----PPPSGGFPPPQ-EGGYPPPQGP--GGYPP
MSMEG_5268|M.smegmatis_MC2_155 PPQGGYPPPPPPGGYP-----PPPQGGFPPPP-PGGYPPPPPPQGGSYPP
Mb1127c|M.bovis_AF2122/97 -------SYPP------------------------AYPPQQYP-------
Rv1097c|M.tuberculosis_H37Rv -------SYPP------------------------AYPPQQYP-------
MMAR_4369|M.marinum_M -------PYPPTGPYTN-------PQGGAPSYGPGTYPPQQFPQAGQPYG
MUL_0182|M.ulcerans_Agy99 -------PYPPTGPYTN-------PQGGAPSYGPGTYPPQQFPQAGQPYG
MAV_1219|M.avium_104 -GQPQGGPYPQPGQYPAGGPYPYPPPGGGYPYPGGPYPGGPYPGAPYPGP
MLBr_02395|M.leprae_Br4923 ---------------------------FAPSELGSAYPPPTAP-------
TH_3438|M.thermoresistible__bu ------WGNPQQPGFPPPGPQQFGPAQPGWGGQWGQPPPPDGPKRNRKAL
MAB_0039c|M.abscessus_ATCC_199 VVRFEQSPNLHTGQFRTRGVVNPDSKRDRPHGAVTTAPPTPDPQPGAPMT
*
Mflv_2044|M.gilvum_PYR-GCK --PPGGYGMPPAGF----GGGYPPPG-----QGYPPVGGP-----PSLDI
Mvan_4673|M.vanbaalenii_PYR-1 --PAG-YGPP--------QGGFPPPA-----QGYPPVGGP-----PAYSV
MSMEG_5268|M.smegmatis_MC2_155 PPPPGAAGYPPPGYPGGPGAGYPPAGGFGQPGGYAPVGAPGF--GGAYSV
Mb1127c|M.bovis_AF2122/97 --PGWPAGPYPPG---------PPPPGPGSKTPWLILAGLAV--LGVILL
Rv1097c|M.tuberculosis_H37Rv --PGWPAGPYPPG---------PPPPGPGSKTPWLILAGLAV--LGVILL
MMAR_4369|M.marinum_M TGPGWPTGPYSPG---------PPPKGPGSKAPWLIIAGVAV--LGVLAL
MUL_0182|M.ulcerans_Agy99 TGPGWPTGPYSPG---------PPPKGPGSKAPWLIIAGVAV--LGVLAL
MAV_1219|M.avium_104 GQPFGPGGPYSPG---------PPPGGPGSKLPWLIVAGLVV--LAVIAL
MLBr_02395|M.leprae_Br4923 --PVGGSYPPP-----------PPPG-----GSYPPPPPPG----GSYPP
TH_3438|M.thermoresistible__bu LVTLGAGAAVLVVLVVVGVIALSGLGGSGDGGSSRSAGAAVQGYLEALAR
MAB_0039c|M.abscessus_ATCC_199 DNPGPQQGRPGEEYGREDDRYGRPDQDPRGQQPQGGQGYPPR--QGGYEG
.
Mflv_2044|M.gilvum_PYR-GCK GAAFSWSFNKFS-KNAVPLIVPTLVYALVIGVLGAVIFGLASLFPADYTS
Mvan_4673|M.vanbaalenii_PYR-1 GDAFNWAWNKFS-KNAMPLIVATLVFGIVVIALQAIINIVQALVSPGDTS
MSMEG_5268|M.smegmatis_MC2_155 GDAFSWAWNKFS-KHAVEMIVPALVFGLVYAILQGIVNGISGAF----TS
Mb1127c|M.bovis_AF2122/97 VVILVIGLRGD--NKSTTATSPATS-APTSQP-FSQQTATGCTPNVSGGV
Rv1097c|M.tuberculosis_H37Rv VVILVIGLRGD--NKSTTATSPATS-APTSQP-FSQQTATGCTPNVSGGV
MMAR_4369|M.marinum_M VVVLVFTLGGNKSNNAGPSGTPATSGDSTSEPDNSEQNATGCTPNVSAGE
MUL_0182|M.ulcerans_Agy99 VVVLVFTLGGNKSNNAGPSGTPATSGASTSEPDNSEQNATGCTPNVSAGE
MAV_1219|M.avium_104 VATLVVMKGGH--GSKPSGATPSSTSTSVSQPKNSAQNATDCTPNVSGGD
MLBr_02395|M.leprae_Br4923 PPPSTGAYAPPPPGPAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLG---
TH_3438|M.thermoresistible__bu GDAEAALSYGAGEPASKELLTDEVLKSQIEKMPISNIRILSDDSDNGVGF
MAB_0039c|M.abscessus_ATCC_199 GGYGQGQPYGQDYGRPPAGYDQGGYQQRPPQQGGYDQGGYGAPPQAPQGG
Mflv_2044|M.gilvum_PYR-GCK YSGADGAGMSLD-------MGPAATIILFLGLIMLFVVGGAISAAYMAGV
Mvan_4673|M.vanbaalenii_PYR-1 YIADD-SGFSFSY----ATTGVAGTIVAIVGWFLSLIVTAAIQSAFLGGI
MSMEG_5268|M.smegmatis_MC2_155 TSSAD--GFELS-------MATGGGVVSIIGAIITLIVTAVIQAAYISGV
Mb1127c|M.bovis_AF2122/97 QPIGD-------------SISAGKLSFPTSAAP-GWSAFSDDQNPNLIDA
Rv1097c|M.tuberculosis_H37Rv QPIGD-------------SISAGKLSFPTSAAP-GWSAFSDDQNPNLIDA
MMAR_4369|M.marinum_M RPLGE-------------IISAGKLSFPISAAP-GWSVFGDDQSPNLIGA
MUL_0182|M.ulcerans_Agy99 RPLGE-------------IISAGKLSFPISAAP-GWSVFGDDQSPNLIGA
MAV_1219|M.avium_104 MPRSD-------------SIAAGKLSFPANAAPSGWTVFSDDQGPNLIGA
MLBr_02395|M.leprae_Br4923 --------------------------------IGMLIQTLTKQEACVTDI
TH_3438|M.thermoresistible__bu GKVHATVNFGDQVSDVTFLMKKSGNVWKLDSAAVRLDLSTQASSNRAMST
MAB_0039c|M.abscessus_ATCC_199 GDYGRPPAPPQQGGGYGAPPQQGGYGEPPRPNYGEYEQGGGYGGGQYGGQ
.
Mflv_2044|M.gilvum_PYR-GCK LDIANGQQVEFGSFFKP------------RNIGAVVIASLIVGIATSIGY
Mvan_4673|M.vanbaalenii_PYR-1 FDIANGQQVAVGSFFRP------------RNVGNVIIAGLIVGVITTVGL
MSMEG_5268|M.smegmatis_MC2_155 LEIANGQPVTIGSFFKP------------RNVGDVIIATVIVGVINFVVA
Mb1127c|M.bovis_AF2122/97 VGVG-HEVAGADQWMMQ------------AEVAITNFVTTMDVAAQASKL
Rv1097c|M.tuberculosis_H37Rv VGVG-HEVAGADQWMMQ------------AEVAITNFVTTMDVAAQASKL
MMAR_4369|M.marinum_M LGVG-QEVPDASQWMMQ------------AEVAVTNFVASMDVSEQASKL
MUL_0182|M.ulcerans_Agy99 LGVG-QEVPDASQWMMQ------------AEVAVTNFVASMDVSEQASKL
MAV_1219|M.avium_104 LGVA-QDVPGANQWMMT------------AEVGVTNFVPSMDLTAQATKL
MLBr_02395|M.leprae_Br4923 TQYN----VNQYCATQP------------TGIGMLAFWFAWLMATAYLVW
TH_3438|M.thermoresistible__bu LTVFGKTVGDSVLYLFPGYIEWGTNNKNVTAQGQPLLLDALTGYAGGSAP
MAB_0039c|M.abscessus_ATCC_199 QGPPPGQDYGRPPAYPQQGGYG--APPQQGGYGSPEYGDYEQGGYQSSPD
.
Mflv_2044|M.gilvum_PYR-GCK VLCIVPG------------------LIVSIFALFTTVFIVDRNLSA----
Mvan_4673|M.vanbaalenii_PYR-1 FLCIVPG------------------VIASFLLMFTTIAVLDRNLAP----
MSMEG_5268|M.smegmatis_MC2_155 AILLFPGFFVPGYLFVGVPVLLIASAIIAVLFLFTTVAVLDRNLSG----
Mb1127c|M.bovis_AF2122/97 MQCVADG--------------------PGYAGSSPTLGPTKTSSIT----
Rv1097c|M.tuberculosis_H37Rv MQCVADG--------------------PGYAGSSPTLGPTKTSSIT----
MMAR_4369|M.marinum_M MQCVVDG--------------------PGYVQSSPTLGPTKKSSTT----
MUL_0182|M.ulcerans_Agy99 MQCVVDG--------------------PGYVQSSPTLGPTKKSSTT----
MAV_1219|M.avium_104 MQCLANG--------------------PGYANAMPTLGPIKTSPIT----
MLBr_02395|M.leprae_Br4923 NYGYRQG---------------------------ATGSSIGKTVMK----
TH_3438|M.thermoresistible__bu KIVLSDSAR---------------KSITSAVRSYLDECARSKSLSPEGCP
MAB_0039c|M.abscessus_ATCC_199 YGAPAGGPG---------------GGRTTVTLQLDDGSGRTYQLREG---
.
Mflv_2044|M.gilvum_PYR-GCK --------IDGIKASIAVAKANFLQVFLTWLIFNVLISVGSFVCYIGLIV
Mvan_4673|M.vanbaalenii_PYR-1 --------MDAIKSSFETSKNNVGPVLLTWLASVAVVFVGALLCGVGLLV
MSMEG_5268|M.smegmatis_MC2_155 --------VDAVKTSFELSKANFGTVFITAVVIFLLLLAGAIACGIGLLV
Mb1127c|M.bovis_AF2122/97 --------VDGVRAARVDADITIADSSRNVKGDSVTIIAVDTKPVTVFLG
Rv1097c|M.tuberculosis_H37Rv --------VDGVRAARVDADITIADSSRNVKGDSVTIIAVDTKPVTVFLG
MMAR_4369|M.marinum_M --------VDGVKAARVDADITIADTSRNVKGDSVVIIAVDTKPVTIFLG
MUL_0182|M.ulcerans_Agy99 --------VDGVKAARVDADITIADTSRNVKGDSVVIIAVDTKPVTIFLG
MAV_1219|M.avium_104 --------VDGTKAVRADADVTIADPTRNVKGDSVTIIAVDTKPVSVFIG
MLBr_02395|M.leprae_Br4923 --------FKVISEATGQPIG-----FGMSVVRQLAHFVDAVICCIGFL-
TH_3438|M.thermoresistible__bu QRAFEYGAVDGTVTWHAPGTDNLQISFDGYSMEARVTLNGQFPYTVQGRD
MAB_0039c|M.abscessus_ATCC_199 ----TNVIGRGQDAQFRLPDTGVSRRHLEVRFDGHAALLSDLNSTNGTTV
Mflv_2044|M.gilvum_PYR-GCK TVPLAVLYMVYAYRTLTGGYVAPATP--
Mvan_4673|M.vanbaalenii_PYR-1 AAPLAALILVYAYRTLNGGFVAPAVP--
MSMEG_5268|M.smegmatis_MC2_155 AYPLVALIEVYAFRRLTGAPIAPPTQ--
Mb1127c|M.bovis_AF2122/97 ATPIGDATSRATVERVIEALKVNKS---
Rv1097c|M.tuberculosis_H37Rv ATPIGDATSRATVERVIEALKVNKS---
MMAR_4369|M.marinum_M ATPIGDAASAATISKVIAALKVDKS---
MUL_0182|M.ulcerans_Agy99 ATPIGDAASAATISKVIAALKVDKS---
MAV_1219|M.avium_104 STPIGDSASAGLIGKIIAALKVAKS---
MLBr_02395|M.leprae_Br4923 -FPLWDSKRQTLADKIMTTVCLPI----
TH_3438|M.thermoresistible__bu GAPINGSDHFMLYGRADLNQTPPVLKWN
MAB_0039c|M.abscessus_ATCC_199 NNAPVTEWQLADGDIIRLGHSEIIVRVQ
.