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ATSRALVDHFARVGNDISHGLGGSLSKAFAAVDGTAARRELLALQQEWRRAADVEADAAARMIRDQRRLA EATVKYGDDSSRTAAAQAMLARSQRDHIDAMIAAEAAHGRLAKAGNETADSVSRLQKLGANPIFNAAGIG SVAGVGIAMDLTTRKAGDLEQQLMKLHAAAGETGEMIGGQFSGNLKTISDGVLQMSGKVGYTTTELMNAM YTIEKAGFRGADALKVLDAAAQGAGSEQADLMEVVNGLTTSMTDFNVKPEQAARLMSQMVTAVGSAKTSF QDFAGALHSVEPVAAAAHLKLEDVWGTLAQLTQSGTSPEQATENMRNAINAFTGQSQPARDAMAQFGINA DEVSQKLSERGLAGTMQYLFDTVQSKLLPGMKLNQGELFKSSQAAADLDEMITQMSPHAAQLATALKNNE ITVKDYTKAARDSVAEDRAKLMEFAQLNDKVDGYSKALRTGRDTIETLGKAMRDMTGTVAGQSVALQVSG DHAQETNDRIKAIATTYTEADGTVKGFHESQDTLNAKMRDAHAAFGAAEAEIGSAFVPVMTEVAKDAKWV GDELAKHPGIAHGVITALEGLGGAWLTFKAIDIVGTILRPIASGLGTIIAQEEGAEVATSRLSTALSGLK AAGILGIGAQLGGQWAQDHTDPNSFLHSASVVGTDTATGAALGAAAGSIIPGVGTAIGAGVGAAGGFAVG LYNQLTSHAEGGPLHAPGPKGHDSALFWGADGEHVLTHQEVQKMGGHSEVYKFRSDLMNGRIVLGRAGGG ALGYGGMAPDVAVASSLAGTPYSQGARDDCSGMVGRVILGAMGLPATNLPTTKNMGQWLAALGFQPGIGG PGSISVGWYDHGPNPNDGHAAMTLSNGENAEAGGSHGNFVIGAGAAGAASSQFDQHMFLPTLYGEGAATG MPGFAAGMGAGGFGGMGGGIPPGATPGTGPGGQPGYYTANPQRVAAAEERLRHLDAEIDNAEKRRSELKA TAKQSERDRLDEEIRHLKAERTQEQQRLAEAERGTFHAMHGRRGAGGGENPFLPVPLADRFGLSKGLPGL AEWTVGFLEDLVLGPLETAAWAAIGQAPPGAGGAGGGFGGLGVPGGLGAARFGFPNPAPLAAPPGAPGAD DAAAAGLDTARGNTIGPTPSSGGAGAGAGASGGGAPSAPADLNGPLTADQIAKLPPDQQLRLLRNAFAHP APPAPAPAPAAPRPQPDADMLPAEVRAWAQQHGMIGPDGNYSGPALPNLGPKSVAPPVKMQPDLSRLGGN TKGPQPPGPPSAPPTPWTESTRGQSWLHDPNAPSWDTGLNLPKLGNQARQFFDLRQPGYFATGGPSGTDT IPAWLSPHEYVEPSEAVDKYGPGFMDAIRQGRIDPTSVRYYAPGGEVTDQPEPPPQQQAPAQQPQNMVKA PGAPGGPAIEPPPGAPKPGDNASIHEPTGPGAVSPGSKQGLSDTATPGADVQQPGTGQGALPGIGFSGGI IGGLEGAATQAAAMGADMGTFGGAGGAVSSAMNIGFQELNRAAAYGAQDVGIGVEGLLEALIPNSDATGA DWSKTIPGRLLMGVTGVRPAGQQNTAGQTQQPFASNASSDQYANVGNTQPQAPIQIMGPVHVQANDPKQL HETSIRRWPSTTQPARSARRGAHRRHTQGEHVAERHHHPLRCRPARRR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_0800 | - | - | 100% (1659) | phage tail tape measure protein, family protein, core region |
M. avium 104 | MAV_4827 | - | 3e-08 | 40.00% (95) | hypothetical protein MAV_4827 |
M. avium 104 | MAV_2415 | - | 8e-08 | 25.52% (482) | hypothetical protein MAV_2415 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 9e-16 | 26.95% (679) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_3843 | - | 6e-19 | 26.47% (612) | hypothetical protein Mflv_3843 |
M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 1e-15 | 27.57% (682) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 2e-05 | 28.32% (173) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_1796 | - | 1e-24 | 21.29% (1301) | bacteriophage tape measure protein |
M. marinum M | MMAR_1195 | - | 2e-17 | 26.80% (735) | PE-PGRS family protein, PE_PGRS9_4 |
M. smegmatis MC2 155 | MSMEG_2146 | - | 3e-15 | 31.23% (269) | gp15 protein |
M. thermoresistible (build 8) | TH_4429 | - | 2e-09 | 20.19% (733) | PUTATIVE - |
M. ulcerans Agy99 | MUL_3062 | - | 8e-19 | 25.30% (739) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_4360 | - | 1e-17 | 30.34% (234) | Phage-related minor tail protein-like |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_2146|M.smegmatis_MC2_155 ----------------------MGIPIPVEPTLDERSATAVAKRAEKAFA Mvan_4360|M.vanbaalenii_PYR-1 -----------------------MVTMVVGTEIDDNSLRQSANDIQRRFD Mb1121|M.bovis_AF2122/97 ------------------------MSFVIAAPEALVAVASDLAGIGSALA Rv1091|M.tuberculosis_H37Rv ------------------------MSFVIAAPEALVAVASDLAGIGSALA MMAR_1195|M.marinum_M ------------------------MSFVIAVPEVVGSAASEVAGIGSALG MUL_3062|M.ulcerans_Agy99 ------------------------MAFVLAVPDMVAEAAADLAGVGSVID Mflv_3843|M.gilvum_PYR-GCK -----------------MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATP TH_4429|M.thermoresistible__bu VTTPVGSIRIDLSIDGSNLGDEITAAVQKHVKAALGELNEVLAEVQAQME MAV_0800|M.avium_104 -------------------MATSRALVDHFARVGNDISHGLGGSLSKAFA MAB_1796|M.abscessus_ATCC_1997 ---------------MAVELSSGYVSATVRFDGVNRGISKLFDNVQKQAV MLBr_01556|M.leprae_Br4923 ------------------------MAGKARVHELAKELGVTSKEVLARLN MSMEG_2146|M.smegmatis_MC2_155 DAGKNAGQAFTGAFSDGARDADQA-----VKKVADRASDAYDKARDAAGR Mvan_4360|M.vanbaalenii_PYR-1 RLGQNVGGDFMTQFADGAAANAPK-----VQKAVD-------KAADATGR Mb1121|M.bovis_AF2122/97 EANAAALAPTTALLAAGADEVSAA-----IAALFGAHGQAYQTVSAQASA Rv1091|M.tuberculosis_H37Rv EANAAALAPTTALLAAGADEVSAA-----IAALFGAHGQAYQTVSAQASA MMAR_1195|M.marinum_M EATAAAAAPTVQVLAAAQDEVSQA-----IAAVFSTHAQAYQAASAQAQS MUL_3062|M.ulcerans_Agy99 AANTAAAGSTTGIVAAAEDEVSAA-----IAALFSGHGQAYQQISTRVAE Mflv_3843|M.gilvum_PYR-GCK TRGGVPCVGILQQIVTRPGEIPQA-----LTDTARSFTEPPKPAPPVVRP TH_4429|M.thermoresistible__bu STSRASASAATGVGQAGKAAREATGGMSDMQQASQAAAQATKTAGDAARA MAV_0800|M.avium_104 AVDGTAARRELLALQQEWRRAADVEADAAARMIRDQRRLAEATVKYGDDS MAB_1796|M.abscessus_ATCC_1997 SAGKRTGSAYAKALADEAKTAADQ-----VKKISETVAKSRDKEADAAGK MLBr_01556|M.leprae_Br4923 EQGEFVKSASSTVEAPVARRLRESFG--GIKPAADKGAEQVATKAQAKRL MSMEG_2146|M.smegmatis_MC2_155 LRAEEEKLKRLRDEGASNDRIVAQAERVEKARRAE--------------- Mvan_4360|M.vanbaalenii_PYR-1 LRSEQEKLDALTANGASRDRIVTQSEKVAKARRDE--------------- Mb1121|M.bovis_AF2122/97 FHAQFVQALTGGGGAYAAAEAANVSAAQSTDQRL---------------- Rv1091|M.tuberculosis_H37Rv FHAQFVQALTGGGGAYAAAEAANVSAAQSTDQRL---------------- MMAR_1195|M.marinum_M LGQRFAQALAAGAGSYSSAEAAAAAVLANPAQVVSG-------------- MUL_3062|M.ulcerans_Agy99 FHAQFERVFAAGVQAYSGAEAANASFLQDPLQTA---------------- Mflv_3843|M.gilvum_PYR-GCK PASSSSSAGTPPVPGRPPASVVTPSSGATPPVPPSPGTPASTSTRGGTPP TH_4429|M.thermoresistible__bu AGSGMDDMGRASDGAADRTSKAGRAASQASGEFGRFSRAAERASAVSKQL MAV_0800|M.avium_104 SRTAAAQAMLARSQRDHIDAMIAAEAAHGRLAKAGN-------------- MAB_1796|M.abscessus_ATCC_1997 LKVALEKLNEAREAGTKGSKLTALSEAHASAMRKQQ-------------- MLBr_01556|M.leprae_Br4923 GESLDQTLDRALDKAVAGNGATTAAPVQVDHSAAVVP------------- MSMEG_2146|M.smegmatis_MC2_155 --------------VRAVRDATDAYREYEQAAQSAGQNA----------- Mvan_4360|M.vanbaalenii_PYR-1 --------------ARAYREATAAVEDYDRAGQRAGN------------- Mb1121|M.bovis_AF2122/97 --------------LDLINGPTQALLGRPLIGDGANGGP----------- Rv1091|M.tuberculosis_H37Rv --------------LDLINGPTQALLGRPLIGDGANGGP----------- MMAR_1195|M.marinum_M ------------DLLAAINAPVLSLTGRPLIGNGANGAP----------- MUL_3062|M.ulcerans_Agy99 --------------LNATNKPVQDLTGRPLVGNGANGVP----------- Mflv_3843|M.gilvum_PYR-GCK VPPAPPAPA--GTPASGATPPAPPVPGVPAVTSTGGGTPPVPPVPGAPVG TH_4429|M.thermoresistible__bu GSGVGQAASGFVRAGDAVLGAVGKFAKWTGIGAAVSGAIGGVAGSFSVLQ MAV_0800|M.avium_104 --------ETADSVSRLQKLGANPIFNAAGIGSVAGVGIAMDLTTR---- MAB_1796|M.abscessus_ATCC_1997 ------------AAASELAKDLDAVARAQKRASDAQSAIDKS-------- MLBr_01556|M.leprae_Br4923 ----------------IVAGEGPSTAHREELAPPAGQPSEQP-------- MSMEG_2146|M.smegmatis_MC2_155 -----------------------------GQNFAGGLRGSLSGIG-AAGQ Mvan_4360|M.vanbaalenii_PYR-1 -------------------------------SFTSGLRSGEAGAA-EAGG Mb1121|M.bovis_AF2122/97 -----------------------------GQ--DGGPGGLLYGNG-GNGG Rv1091|M.tuberculosis_H37Rv -----------------------------GQ--DGGPGGLLYGNG-GNGG MMAR_1195|M.marinum_M -----------------------------GTGANGAAGGWLLGDG-GAGG MUL_3062|M.ulcerans_Agy99 -----------------------------GTGANGAAGGWLLGNG-GAGG Mflv_3843|M.gilvum_PYR-GCK A-----------------------PVANPGLPTPPVPGAPVFGDG-GAVL TH_4429|M.thermoresistible__bu LGMNRLTSIENARSTLQGLGHDARSVEGIMDSALTAVKGTAFGLG-EAAT MAV_0800|M.avium_104 ----------------------------KAGDLEQQLMKLHAAAG-ETGE MAB_1796|M.abscessus_ATCC_1997 -----------------------------SKPIRNQVSKLLSGSSDAAGR MLBr_01556|M.leprae_Br4923 -----------------------------GVPLPGQQGTPAAPHPGHPGM MSMEG_2146|M.smegmatis_MC2_155 -DAANEFVGGFAGSSALLRLGSAGGPIGLALAGVATLGVMGGRLLANGIA Mvan_4360|M.vanbaalenii_PYR-1 -GFADSFAGGFAGASSLSGLGGG----LLKAGGWITAGIAAGKLFSDAVG Mb1121|M.bovis_AF2122/97 TSTTAGVAGGNGGAAGLIGNGGAGGGGGAG--------AAGGNGGAGGWL Rv1091|M.tuberculosis_H37Rv TSTTAGVAGGNGGAAGLIGNGGAGGGGGAG--------AAGGNGGAGGWL MMAR_1195|M.marinum_M -SGAPGMAGGNGGAAGLWGTGGAGGAGGRT---FNGDGGNGGAGGAGGWL MUL_3062|M.ulcerans_Agy99 -SGAAGQAGGDGGAAGLIGAGGAGGAGGNSPLRNTANGGNGGTGGAGGLL Mflv_3843|M.gilvum_PYR-GCK PPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGVALPPAPPGAPGAPV TH_4429|M.thermoresistible__bu VAASAVAAGVQPGEDLTRTLKLVGDAAAIAKTDMQSMGAIFNKVATSNKV MAV_0800|M.avium_104 MIGGQFSGNLKTISDGVLQMSGKVGYTTTELMNAMYTIEKAGFRGADALK MAB_1796|M.abscessus_ATCC_1997 EGGLAGRRFGDSFSSALRTTGIVAAGTAVGNLAANAMTKAASLATSGVSA MLBr_01556|M.leprae_Br4923 PTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRPSASPSSMS .. MSMEG_2146|M.smegmatis_MC2_155 DGLQTLQVQD---------------------------------------- Mvan_4360|M.vanbaalenii_PYR-1 DGMATIQLRD---------------------------------------- Mb1121|M.bovis_AF2122/97 YGNGGAGGAG---------------------------------------- Rv1091|M.tuberculosis_H37Rv YGNGGAGGAG---------------------------------------- MMAR_1195|M.marinum_M MGTGGAGGAG---------------------------------------- MUL_3062|M.ulcerans_Agy99 FGPGGVGGAG---------------------------------------- Mflv_3843|M.gilvum_PYR-GCK FGEAGAAPSG---------------------------------------- TH_4429|M.thermoresistible__bu QGEVMAQLHDRGIPILQLLSEEIGKTAEETAKMASDGKIDFETFRNAIER MAV_0800|M.avium_104 VLDAAAQGAGSE-------------------------------------- MAB_1796|M.abscessus_ATCC_1997 VVTKGLDFEK---------------------------------------- MLBr_01556|M.leprae_Br4923 PRPGGAVGGG---------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 ---LIA-TRMGLDGATMNRFGNAAGQAYANGWGQSLEDNLRSLQFGVQSG Mvan_4360|M.vanbaalenii_PYR-1 ---QFQ-ARMGLDDSAMAEFGDAAGRAYANNFGLSLEDTLSTSQAALRTK Mb1121|M.bovis_AF2122/97 ---GTS-VIPG-VAGGNGGAGGSAGLWGTGGAGG--DGGNGRSGPVNVAG Rv1091|M.tuberculosis_H37Rv ---GTS-VIPG-VAGGNGGAGGSAGLWGTGGAGG--DGGNGRSGPVNVAG MMAR_1195|M.marinum_M ---GAG-GFSGTGDGGSGGAGGAGGLLGGGGVGG--AGGFSNGG----TG MUL_3062|M.ulcerans_Agy99 ---GAS-FLT----GGTGGDGGAGGLFGAGGLGG--VGGSGN------VG Mflv_3843|M.gilvum_PYR-GCK ---AAAPVAPAAGSGGAGGAGGGSGIGGPGGGGAPVEGTGGAVPAGAPLA TH_4429|M.thermoresistible__bu GMGGAALKAGETFEGAMANMRAALGRLGAEILKGPFESAPAVIGRVTEGI MAV_0800|M.avium_104 --QADLMEVVNGLTTSMTDFNVKPEQAARLMSQMVTAVGSAKTSFQDFAG MAB_1796|M.abscessus_ATCC_1997 ----TMNTLSGVTGASADVMQRFRDTAKALGNDMTLSNTSAADAAQAMTE MLBr_01556|M.leprae_Br4923 ---GPRPPRTGVPRPGGGRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGG MSMEG_2146|M.smegmatis_MC2_155 LIGPDV-------------------------------------------- Mvan_4360|M.vanbaalenii_PYR-1 LVDPDA-------------------------------------------- Mb1121|M.bovis_AF2122/97 SAGGNG-------------------------------------------- Rv1091|M.tuberculosis_H37Rv SAGGNG-------------------------------------------- MMAR_1195|M.marinum_M GVGGTG-------------------------------------------- MUL_3062|M.ulcerans_Agy99 GNGGAG-------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK AAGGEVPP------------------------------------------ TH_4429|M.thermoresistible__bu DVATDAVKGMVTYLRTGEVTDTFRDVFGRGDMSRRVLAGLERVRTVARQV MAV_0800|M.avium_104 ALHSVEP------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 LA-KAG-------------------------------------------- MLBr_01556|M.leprae_Br4923 FRGRPG-------------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4360|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1121|M.bovis_AF2122/97 -------------------------------------------------- Rv1091|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1195|M.marinum_M -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK -------------------------------------------------- TH_4429|M.thermoresistible__bu RDGFEELQAAWRGDDGAADWATKAVDFVRDSLARVWDIAKQLGPALAGIA MAV_0800|M.avium_104 -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 -------------------------------------NEADAQKFIER-- Mvan_4360|M.vanbaalenii_PYR-1 -------------------------------------TAAEVQAVIEQ-- Mb1121|M.bovis_AF2122/97 -------------------------------------GAGG-AAGLFG-- Rv1091|M.tuberculosis_H37Rv -------------------------------------GAGG-AAGLFG-- MMAR_1195|M.marinum_M -------------------------------------GAGGVLSGVVG-- MUL_3062|M.ulcerans_Agy99 -------------------------------------GAGGLLAGLVG-- Mflv_3843|M.gilvum_PYR-GCK --------------------------PAPPIPGAPVIGEAGVVPPPAPPA TH_4429|M.thermoresistible__bu ASFAKASAAVGVSAWTIFLRTAEALVPILTTIADLITSHQGVVTALVAAY MAV_0800|M.avium_104 -------------------------------------VAAAAHLKLEDVW MAB_1796|M.abscessus_ATCC_1997 ------------------------------------FSVDESITAAKGTL MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 ---IQATSGVLEEDPQQIARGVRNFVKTGLVSDYEQAF--------DLIV Mvan_4360|M.vanbaalenii_PYR-1 ---LEGMEAVTEATATELSRSMATLMRTGLADSMSEAS--------DIIT Mb1121|M.bovis_AF2122/97 ---DAG-AGGNGGKGGAGGAAFSINFTAGD-GGAGGAG--------GSGG Rv1091|M.tuberculosis_H37Rv ---DAG-AGGNGGKGGAGGAAFSINFTAGD-GGAGGAG--------GSGG MMAR_1195|M.marinum_M ---AGGGHGGTGGYGAFDGGAGGVGGHAGLLGGPGGAG--------GDGG MUL_3062|M.ulcerans_Agy99 ---AGGGDGGSGGLGAAGG-DGGNGGRAGLFGGAGGAG--------GMG- Mflv_3843|M.gilvum_PYR-GCK PAPPAGGLGGAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVV TH_4429|M.thermoresistible__bu ALLKTGFIGAAVAAKGLAVIKTVTGWMTGLIGVTTAAGTVMSTTLTTVAT MAV_0800|M.avium_104 GTLAQLTQSGTSPEQATENMRNAINAFTGQSQPARDAMAQFGINADEVSQ MAB_1796|M.abscessus_ATCC_1997 QLAAAAQVSAGQAAEIQANALQAFGLKADYASKAADVLS-------NAAN MLBr_01556|M.leprae_Br4923 ----GGGHGGGGRPGQRGGAAGAFGRPGGAPRRGRKSK------------ . . MSMEG_2146|M.smegmatis_MC2_155 ASTQKGLNISNDLLDTFEEYGTKFRDLGINGQEALGLINQLWEGGARNVD Mvan_4360|M.vanbaalenii_PYR-1 AGFQSGLDVSGDWLDTINEYSTQFRKFGLDAGEFMTLLSQGLEGGARDTD Mb1121|M.bovis_AF2122/97 HALLWGAGGA-----------------GGNGGSG----GTGGAGGSTAG- Rv1091|M.tuberculosis_H37Rv HALLWGAGGA-----------------GGNGGSG----GTGGAGGSTAG- MMAR_1195|M.marinum_M DTFGGGSGGA-----------------GGAGGDGGWAFGSGGTGGTGG-- MUL_3062|M.ulcerans_Agy99 -ATGGHSGGD-----------------GGAGGDAGLLFGTGGAGGAGGHA Mflv_3843|M.gilvum_PYR-GCK TPPAPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPGAPV TH_4429|M.thermoresistible__bu DADGLGSSMGGLGERTKKGMRETLRSLKALRGEIGTTMLMAGTAATATSS MAV_0800|M.avium_104 KLSERGLAGTMQYLFDTVQSKLLPG-MKLNQGELFKSSQAAADLDEMITQ MAB_1796|M.abscessus_ATCC_1997 ASSAEITDVAFALQAGGSVARQTGVSLEDTAASIALLANNGIKGSDAGTL MLBr_01556|M.leprae_Br4923 ----------------------------RQKRQEYDSMQAPVVGGVRLPH MSMEG_2146|M.smegmatis_MC2_155 VAADALKEFAITVVDNSDTTKTALTALGFDAEELG--------------- Mvan_4360|M.vanbaalenii_PYR-1 KVADSLKEFSIRAVDGSQSTAEAFAALGFSADEMG--------------- Mb1121|M.bovis_AF2122/97 AGGNG--------------------GAGGGGGTGG--------------- Rv1091|M.tuberculosis_H37Rv AGGNG--------------------GAGGGGGTGG--------------- MMAR_1195|M.marinum_M YGGAG--------------------GAGGSGGDAG--------------- MUL_3062|M.ulcerans_Agy99 FDGDG--------------------GAGGAGGNAG--------------- Mflv_3843|M.gilvum_PYR-GCK VDEAG----------VVTPPAPGGPGVPAVGDTAV--------------- TH_4429|M.thermoresistible__bu GIAQTIGALSSVAGGALAGSIFGPAGAAIGAGIGGGIALASYLLGENARA MAV_0800|M.avium_104 MSPHAAQLATALKNNEITVKDYTKAARDSVAEDRAKLMEFAQLN------ MAB_1796|M.abscessus_ATCC_1997 LKSALLKLSAPSDQASGALQELGVSAFDAQGNFVG--------------- MLBr_01556|M.leprae_Br4923 GNGETIR-------------------LARGASLSD--------------- . MSMEG_2146|M.smegmatis_MC2_155 ----------------------------------RKFAEGGPTARAAFGA Mvan_4360|M.vanbaalenii_PYR-1 ----------------------------------RMFAQGGDSAKVALDA Mb1121|M.bovis_AF2122/97 ----------------------------------LLFGNGGAG---GHGA Rv1091|M.tuberculosis_H37Rv ----------------------------------LLFGNGGAG---GHGA MMAR_1195|M.marinum_M ----------------------------------LLFSNGGAGGTGGFG- MUL_3062|M.ulcerans_Agy99 ----------------------------------LMFSSGGSGGVGGAGS Mflv_3843|M.gilvum_PYR-GCK ----------------------------------VTPPAPGAPGTPAVNS TH_4429|M.thermoresistible__bu ARAAAAAQAELAQQVQRAKEAQLASLGAQKELNAALLESAGVVDEAAVAA MAV_0800|M.avium_104 -------------------------------DKVDGYSKALRTGRDTIET MAB_1796|M.abscessus_ATCC_1997 -----------------------------MEALFGQLQAASKRMTPEMYA MLBr_01556|M.leprae_Br4923 ------------------------------------FAEKIDANPAALVQ MSMEG_2146|M.smegmatis_MC2_155 VLDALASVKDPMEQERIGLDLF------------------KTKWEDVGDA Mvan_4360|M.vanbaalenii_PYR-1 TFDAIKRIDDPMQQSLIWQQLF------------------GTQFEDMGDA Mb1121|M.bovis_AF2122/97 AAGNGL-------------------------------------------- Rv1091|M.tuberculosis_H37Rv AAGNGL-------------------------------------------- MMAR_1195|M.marinum_M ETGGEG-------------------------------------------- MUL_3062|M.ulcerans_Agy99 IDGGAG-------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK VETFSPPAPPAATPPSSG-------------------------------- TH_4429|M.thermoresistible__bu VARTIDNLPEMLRGRLSDEQVQGVVESIQKLGVSSESLASQLTRGGPALD MAV_0800|M.avium_104 LGKAMRDMTGTVAGQSVALQVSG-----------------DHAQETNDRI MAB_1796|M.abscessus_ATCC_1997 MNTALAFGSDAARLAGVAAKDG------------------------AAGF MLBr_01556|M.leprae_Br4923 ALFNLG-------------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 IKNLDLPSAANELGNVAGKTDEATG-ALQRHADGWDTLGRNIDETFRKFK Mvan_4360|M.vanbaalenii_PYR-1 INRFDLDPVKNQFADIEGVAARSTQTATDNFSSKWGTATRTVGQYFSDLK Mb1121|M.bovis_AF2122/97 -------AAGNGVSSSGGGGAGGTGGAG--GDGGAGGAGG-NARLWGVGG Rv1091|M.tuberculosis_H37Rv -------AAGNGVSSSGGGGAGGTGGAG--GDGGAGGAGG-NARLWGVGG MMAR_1195|M.marinum_M -------GAGGGAGWLGDGGAGGTGGAANIGSGGDGGGGGTGGTLLGNGG MUL_3062|M.ulcerans_Agy99 -------GAGGDAGWLGGGGAGGAGGFGTISDGGAGGRGGGGGQLLGNGG Mflv_3843|M.gilvum_PYR-GCK -SVETFSPPAPPAPGTGTNSTVEISTPPPPGTPGLPSEGSTTYTTPPTPE TH_4429|M.thermoresistible__bu ATLAALRAMGGPDGERAADALLGVAARFDHARTRAEAAAPALSEMAQKMG MAV_0800|M.avium_104 KAIATTYTEADGTVKGFHESQDTLNAKMRDAHAAFGAAEAEIGSAFVPVM MAB_1796|M.abscessus_ATCC_1997 DKMRDAMNQEGSASKLAAAQNQGLPGVIERLKNAAETLAITLFEKIQGPL MLBr_01556|M.leprae_Br4923 --------EMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLEPFD MSMEG_2146|M.smegmatis_MC2_155 EWLADSAIGT-FFSQTLPGFLNAPFEQP---------------------- Mvan_4360|M.vanbaalenii_PYR-1 TDIAAWFSGLPIVSDVLPEMLTTLFGDQ---------------------- Mb1121|M.bovis_AF2122/97 AGGAGGDGG----------------------------------------- Rv1091|M.tuberculosis_H37Rv AGGAGGDGG----------------------------------------- MMAR_1195|M.marinum_M AGGAGGHGPT---------------------------------------- MUL_3062|M.ulcerans_Agy99 AGGAGGQGGN---------------------------------------- Mflv_3843|M.gilvum_PYR-GCK ITLNPANSGIDIATPPAPGLPGAPLEAT---------------------- TH_4429|M.thermoresistible__bu VDVLQAADDLSVALKAVPQNIPLNMDMPGAEALVGLLREAGAAVEVLGDG MAV_0800|M.avium_104 TEVAKDAKWVGDELAKHPGIAHGVITALEG-------------------- MAB_1796|M.abscessus_ATCC_1997 SSIGDGLTGFTNKMQDAFENPAVSQAAG---------------------- MLBr_01556|M.leprae_Br4923 LTYGEDQGDE---------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4360|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1121|M.bovis_AF2122/97 -------------------------------------------------- Rv1091|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1195|M.marinum_M -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK -------------------------------------------------- TH_4429|M.thermoresistible__bu TVHLDVNDERVRDAITVVDSLGWAIKQVPDTKQIEITVKTDEAALQRFIS MAV_0800|M.avium_104 -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 -----------------------PPPPPPAPGQSLGD--SGIYGPPVQGP Mvan_4360|M.vanbaalenii_PYR-1 -----------------------PRLQAPGAIQGAVP--GTPLNPLDIAA Mb1121|M.bovis_AF2122/97 ----------------------------AGGAGGKGG--SGLSGNANGGA Rv1091|M.tuberculosis_H37Rv ----------------------------AGGAGGKGG--SGLSGNANGGA MMAR_1195|M.marinum_M ----------------------------DGGAGGTGG--NAVV-VGNGGN MUL_3062|M.ulcerans_Agy99 ----------------------------DGGAGGLGG--NGVL-IGNGGN Mflv_3843|M.gilvum_PYR-GCK -----------------------ANITTPGTPGVPGAPVNSSIDVATPGE TH_4429|M.thermoresistible__bu QMTTEMQKFTTLWITPQLTGEIPAGQPRPNPTAGGNALDPGFFIPGGRAD MAV_0800|M.avium_104 -------------------------LGGAWLTFKAIDIVGTILRPIASGL MAB_1796|M.abscessus_ATCC_1997 --------------------------NIGSALSTIGTAFGNVLSAVGPSL MLBr_01556|M.leprae_Br4923 ------------------------------DELQVRPPVVTVMGHVDHGK . MSMEG_2146|M.smegmatis_MC2_155 GLNGDGVQVPSDSALPPFLTPGLTGPG----------------------- Mvan_4360|M.vanbaalenii_PYR-1 GGTGGWWGTSNVPQAETGVPGVVLPPD----------------------- Mb1121|M.bovis_AF2122/97 GGDSG--------------RGGTGGAG----------------------- Rv1091|M.tuberculosis_H37Rv GGDSG--------------RGGTGGAG----------------------- MMAR_1195|M.marinum_M GGIGG--------------TGPTTGTT----------------------- MUL_3062|M.ulcerans_Agy99 GGVGG--------------VGETPGGD----------------------- Mflv_3843|M.gilvum_PYR-GCK VGVPAAPIERSMTVTTPDTPGAPGAPANAAVDVA---------------- TH_4429|M.thermoresistible__bu GGVLPGYSPGRDNMLVPLSGGEGIIIPEAMRALGGSWLYQLNSRFRPGIS MAV_0800|M.avium_104 GTIIAQEEGAEVATSRLSTALSGLKAAG---------------------- MAB_1796|M.abscessus_ATCC_1997 VSGLSDAVNLIVRFKDFLIPLVAGLAAYKT-------------------- MLBr_01556|M.leprae_Br4923 TRLLDTIRKAN--------VREAEAGG----------------------- MSMEG_2146|M.smegmatis_MC2_155 -----------LVDPRINAPIPAQPTIP-----------LGPPPPDSPER Mvan_4360|M.vanbaalenii_PYR-1 -----------AASTPLGELLLPSQQGP-----------TPPTGPVAPRP Mb1121|M.bovis_AF2122/97 -----------GEGGAAGLLVGTGGHGG-----------DGGAGGAAVKG Rv1091|M.tuberculosis_H37Rv -----------GEGGAAGLLVGTGGHGG-----------DGGAGGAAVKG MMAR_1195|M.marinum_M -----------GAGGIGGLLLGLDGYNA-----------PTSTSPIHVAQ MUL_3062|M.ulcerans_Agy99 -----------GGGGISGLLLGADGFNA-----------PAGSSPVHALQ Mflv_3843|M.gilvum_PYR-GCK --------TPPAPGVPGAPVVGEAGVTT-----------PGAPGAPGAPA TH_4429|M.thermoresistible__bu RRGYADGGVHRGSGALPGPVFDTRDDDEPLKLLEDIRDLLAGAGPTTAPL MAV_0800|M.avium_104 ---------ILGIGAQLGGQWAQDHTDP-----NSFLHSASVVGTDTATG MAB_1796|M.abscessus_ATCC_1997 --------VMLAITVATKAWAAVQALLN-----------IALTANPIGLI MLBr_01556|M.leprae_Br4923 -----------ITQHIGAYQVGVDLDGS-----------ERLITFIDTPG MSMEG_2146|M.smegmatis_MC2_155 GPGMPYDQAQQQVADAGRTDSAKPSFDPSQYSVDAIPVPGAIPMPAVAGA Mvan_4360|M.vanbaalenii_PYR-1 TAPTQGTPVPIVPDGADAGSGDKPVIDPSRYSLDSVPIS--IRPDQLPGV Mb1121|M.bovis_AF2122/97 GDGGAAAGTGIAGAGGRGGAGGSGGSGGDGGGGAAGPAGWLFGDGGAGGN Rv1091|M.tuberculosis_H37Rv GDGGAAAGTGIAGAGGRGGAGGSGGSGGDGGGGAAGPAGWLFGDGGAGGN MMAR_1195|M.marinum_M QQALVAINSPVQDLTGRPLIG-NGTPAPAGSGADGTPGGWLLGDGGAGGS MUL_3062|M.ulcerans_Agy99 QQALAAINAPVQELTGRPLIG-NGLPGSAGSGAAGAPGGWLLGDGGAGGS Mflv_3843|M.gilvum_PYR-GCK NAAVDVATPPAPGVPGAPVVGEAAVTTPGAPGVPGVPAGGDAGVVTPPAP TH_4429|M.thermoresistible__bu NVTAREVSTLADRAVGRMAGMTPGGTGPFGTPIAPRHRGYEMAAAAISAL MAV_0800|M.avium_104 AALGAAAGSIIPGVGTAIGAGVGAAGGFAVGLYNQLTSHAEGGPLHAPGP MAB_1796|M.abscessus_ATCC_1997 IAAIAGLVAGIVVLYKRNETFRNIVQATWTAIKNVIGAVWGWLSTTVFPA MLBr_01556|M.leprae_Br4923 HEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAV MSMEG_2146|M.smegmatis_MC2_155 PGAPMPGAGGGMGYYEVDPQRVYDAETSVLSARNSVESARIRVLELEAEG Mvan_4360|M.vanbaalenii_PYR-1 ASSPS------------MSQQVWDMETQLLSQRQSVEEARLRVLELEAGG Mb1121|M.bovis_AF2122/97 GGAA------------------------------------------AAGG Rv1091|M.tuberculosis_H37Rv GGAA------------------------------------------AAGG MMAR_1195|M.marinum_M AVAGSD----------------------------------------GAGG MUL_3062|M.ulcerans_Agy99 AAATPG----------------------------------------AAGG Mflv_3843|M.gilvum_PYR-GCK GVPGAPVVG-------EAGVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGA TH_4429|M.thermoresistible__bu GGDPEKWLGAEPVSYWRERINESVQAVQQATSAMGPVVSDMGRYVEALQE MAV_0800|M.avium_104 KGHDSALFWGADGEHVLTHQEVQKMGGHSEVYKFRSDLMNGRIVLGRAGG MAB_1796|M.abscessus_ATCC_1997 LKTAFTAIGTGAMWLWNNAIKPAWNGIKEVIGLAWEVASDLFANWKRAMD MLBr_01556|M.leprae_Br4923 NKIDK-----------------------------------------EGAD MSMEG_2146|M.smegmatis_MC2_155 NATAQQLATARQQVTMAERQYVSAQMRLSEAQQGTWKKMENAAKGFSKGM Mvan_4360|M.vanbaalenii_PYR-1 TATQSEINAARTAQQIAERQYVSQLQKLAEAQQGTWQKLEDSAASFASGM Mb1121|M.bovis_AF2122/97 AGGQAG--GGGGNGGNGGNG--GNGGNGGNGATGGWLYGNGGAGGQGATA Rv1091|M.tuberculosis_H37Rv AGGQAG--GGGGNGGNGGNG--GNGGNGGNGATGGWLYGNGGAGGQGATA MMAR_1195|M.marinum_M SGGAAGLWGTGGTGGAGARSTTGNGGAGGAGGAGGWLSGDGGTGGTGGAA MUL_3062|M.ulcerans_Agy99 AGGAAGLVGAGGAGGAGANTGISNPGFGGAGGAG----------GAG--- Mflv_3843|M.gilvum_PYR-GCK PAATEAGLATPPGPGAPGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPP TH_4429|M.thermoresistible__bu FARTGDLSAVQGVGLSATDSVITAITSARNKKTGRLSDTEIGALIEQTLG MAV_0800|M.avium_104 GALGYGGMAPDVAVASSLAGTPYSQGARDDCSGMVGRVILGAMGLPATNL MAB_1796|M.abscessus_ATCC_1997 LLGQGALWLWNNAISPAWEGIKTAISAAWRFVSPILDKFSEGWDALKSGI MLBr_01556|M.leprae_Br4923 PAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAAL MSMEG_2146|M.smegmatis_MC2_155 DD--IGAALDNDLGISEGLPGLADNLVRFVASLAAAPLLGPLSAISAANP Mvan_4360|M.vanbaalenii_PYR-1 ED--IGAALDSDFGLSEGLPGLAENLTKFIANLAAAPLLGQLSAIKQAAG Mb1121|M.bovis_AF2122/97 G---AGGAGANGVSSTNGG----------------------------GNG Rv1091|M.tuberculosis_H37Rv G---AGGAGANGVSSTNGGG-------------------------TGGNG MMAR_1195|M.marinum_M TF--NGATGGNGGDAGNGG--------------------------LFGAG MUL_3062|M.ulcerans_Agy99 ----AGAGGGVGEAGGAGG--------------------------LLGAG Mflv_3843|M.gilvum_PYR-GCK AP--VAPVEGAGGAVPPAGPPPAPVFGDAGAPVEAAAG----GAPVEAAA TH_4429|M.thermoresistible__bu PSGYVGVLDERNASLVKSLQSFRDKVAKGSGTMTGGALVAG----LPAHT MAV_0800|M.avium_104 PTTKNMGQWLAALGFQPGIGGPGSISVGWYDHGPNPNDGHAAMTLSNGEN MAB_1796|M.abscessus_ATCC_1997 SG-ASSAIKDAVTSAFSGLAAVIKAPLKVLGTFLAAIPSEVFGFQIPGAD MLBr_01556|M.leprae_Br4923 DLRANSGMEAQGVAIEAHLD-----------------------------R MSMEG_2146|M.smegmatis_MC2_155 IQGGHGILGILGAQGAFGPQYTQSQYAQQGYGYPAGYAAGGYP-----GD Mvan_4360|M.vanbaalenii_PYR-1 DEG-SGLMGILASNGAFGPRFMPNNNGIGAPGYSPSTMGPAEL-----QQ Mb1121|M.bovis_AF2122/97 GIGGTGGSGGAGGNAGLLGVGGAGGHG--ASGGAGDRGGAGGT-----GF Rv1091|M.tuberculosis_H37Rv GIGGTGGSGGAGGNAGLLGVGGAGGHG--ASGGAGDRGGAGGT-----GF MMAR_1195|M.marinum_M GNGGAGGAG--LGNPGFGGAGGNGGAGGLLSGLVGAGGGHGGA-----GG MUL_3062|M.ulcerans_Agy99 GTGGGGGVAPSLVDGGTGGAGGAGGAGGLFGGIFGAGGGDGGA-----GG Mflv_3843|M.gilvum_PYR-GCK GVTGGGSVAGAGAGGGAGGAAGGAGVEGASGAVGAAGGPGAGA-----AP TH_4429|M.thermoresistible__bu GAATFSTSGLMPATAALGQAVLQMFPQIREIGGYRQDPHPDHP-----SG MAV_0800|M.avium_104 AEAGGSHGNFVIGAGAAGAASSQFDQHMFLPTLYGEGAATGMPGFAAGMG MAB_1796|M.abscessus_ATCC_1997 KLNSWGKSLQGFAAGGMVRGAGTGTSDSILAWLSNGEGVVTAKG-MKNGG MLBr_01556|M.leprae_Br4923 GRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHG----------VD . MSMEG_2146|M.smegmatis_MC2_155 AALLANVPAGR-YSQTGIADLTQGIADCSSAVEDLVNLLDGRPTGGRSLS Mvan_4360|M.vanbaalenii_PYR-1 AMTYGVTGGGAPYGLPAGSGSGAQFPAWVRQLERIFGVSASTYAGHQERD Mb1121|M.bovis_AF2122/97 ISSDGGAGGDGGDGGNGGAG------------------------------ Rv1091|M.tuberculosis_H37Rv ISSDGGAGGDGGDGGNGGAG------------------------------ MMAR_1195|M.marinum_M LGVSPSTPAALAGGGIGGAG------------------------------ MUL_3062|M.ulcerans_Agy99 F-----TGGIDGAGGVGGAG------------------------------ Mflv_3843|M.gilvum_PYR-GCK AAAGGAAPGGAPGGPVAGGGP----------------------------- TH_4429|M.thermoresistible__bu RAIDIMIPGGTTRGGRNPAGEALGDQIWNWLMSTGIVDPKGS-------- MAV_0800|M.avium_104 AGGFGGMGGGIPPGATPGTGPGGQPGYYTANPQRVAAAEERLRHLDAEID MAB_1796|M.abscessus_ATCC_1997 AGIVAALNSGWVPSAAYLHDMMRAPGYAQG-------------------- MLBr_01556|M.leprae_Br4923 IEAALPSSPVQVIGFTSVPG------------------------------ . . MSMEG_2146|M.smegmatis_MC2_155 THN-----------ADEWLRERGFLPGAGGPGDFRVGFNASHMQATLPGG Mvan_4360|M.vanbaalenii_PYR-1 GLNKG---IDWSGPVENMQRFADYLATIPGSLEQVIWQNPNTGGKTGIAD Mb1121|M.bovis_AF2122/97 -------------------GTGGLLFGAGGNG--------------GPGG Rv1091|M.tuberculosis_H37Rv -------------------GTGGLLFGAGGNG--------------GPGG MMAR_1195|M.marinum_M -------------------GDAGLLGGAGGAG--------------GTGG MUL_3062|M.ulcerans_Agy99 -------------------GNTGLLGGPGGSG--------------GSGG Mflv_3843|M.gilvum_PYR-GCK ------------------VGGPGALPAPGAPIVGEAGVVSPPAPG-VPGG TH_4429|M.thermoresistible__bu -------------LWKTDVGGDHFDHIHARIAEGMENAAIQAGLIPAAAG MAV_0800|M.avium_104 NAEKRRSELKATAKQSERDRLDEEIRHLKAERTQEQQRLAEAERGTFHAM MAB_1796|M.abscessus_ATCC_1997 -----------------LNPGADYLRSLVMKMWPQIKDIGGRRAEDGFGE MLBr_01556|M.leprae_Br4923 -------------------AGDNFLVVDEDRIARQIADRRSARKRNALAA . MSMEG_2146|M.smegmatis_MC2_155 TPFNWGSDSAAARRGIGGTGADDPAFTSHYYRPAVAGSASVPTIPAAPSV Mvan_4360|M.vanbaalenii_PYR-1 GQFVGPGTSQPGYYANDWGGHQDHVHTRQSYSLPVPAAPAVPPVPSYPQY Mb1121|M.bovis_AF2122/97 SG----GAADIGGNGGAG-------------------------------- Rv1091|M.tuberculosis_H37Rv SG----GAADIGGNGGAG-------------------------------- MMAR_1195|M.marinum_M S--GAFDVTSTGGTGGAGG------------------------------- MUL_3062|M.ulcerans_Agy99 DGIAKLGFNVDGGAGGAGV------------------------------- Mflv_3843|M.gilvum_PYR-GCK AAAVPAGAVTPPAPGVPGAPVFGEAGVVTPPAPGVPGGAAAVPAG----- TH_4429|M.thermoresistible__bu TPAASLGGLSATGGATPVFVTNWPGTGGMGMPPGLQPILDAAAQGSGEAA MAV_0800|M.avium_104 HGRRGAGGGENPFLPVPLADRFGLSKGLPGLAEWTVGFLEDLVLGPLETA MAB_1796|M.abscessus_ATCC_1997 HSSGNAIDIMIPGWDTPQGKALGDAVAAFIAKNASALGLDGFIWR----- MLBr_01556|M.leprae_Br4923 RSRKRISLEDLDSALKETS------------------------------- MSMEG_2146|M.smegmatis_MC2_155 TVYPSTASASPSTAADIYSPANTNPALNNPATPATTPSSLPPVSGGGGTL Mvan_4360|M.vanbaalenii_PYR-1 QPSTGVAPAPAPVLPSAPVNAGPLPPLPAPGTVPSGGSAMP-GTGFPQAP Mb1121|M.bovis_AF2122/97 ------------------------------------NGGGTDGNGGNGGS Rv1091|M.tuberculosis_H37Rv ------------------------------------NGGGTDGNGGNGGS MMAR_1195|M.marinum_M ------------------------------------NAGFLFGSGGIGGP MUL_3062|M.ulcerans_Agy99 ------------------------------------NGGFLFGSGGTGGF Mflv_3843|M.gilvum_PYR-GCK --------VVTPPAPGVPGGAAAVPAGAVTPPAPGVPGAPVFGDAGVATP TH_4429|M.thermoresistible__bu SNVLGDVMSAVASLGQEDWAKRDASYATLNKLVRDRNPMALAAALGLDVE MAV_0800|M.avium_104 AWAAIGQAPPGAGGAGGGFGGLGVPGGLGAARFGFPNPAPLAAPPGAPGA MAB_1796|M.abscessus_ATCC_1997 --------QQSYGYGGSLTSGKQMPDRGSSTQNHMDHVHVMLGKGRGAGA MLBr_01556|M.leprae_Br4923 ----------------------------------QLNLILKGDNAGTVEA MSMEG_2146|M.smegmatis_MC2_155 PFMGQGGPQAAPFALNTPVGG--SAFPAQGGGGFQGVSGLPMDAIMTATQ Mvan_4360|M.vanbaalenii_PYR-1 AFMAPPGTPGNPIGQSVIPGQPPGVVPGAGAGMTGGISGIPLAAASAAAS Mb1121|M.bovis_AF2122/97 G-----GGAGSGGDGGGAGGNGAWLFGNGGAGGGGGK---------GGNG Rv1091|M.tuberculosis_H37Rv G-----GGAGSGGDGGGAGGNGAWLFGNGGAGGGGGK---------GGNG MMAR_1195|M.marinum_M G-----GFAVAASGNGGQGGHAGLLWSSGGAGGAGAFSVSGPAGAGGHGG MUL_3062|M.ulcerans_Agy99 GGVGGVGTSTGIGGAGGRGGNAGLLFSDAGVGGFGGF--------GGTGG Mflv_3843|M.gilvum_PYR-GCK PVPGVPGGGTTVPAASVTPPAPGVPGGASTVPGNAGTPSTPGLPPGSTDT TH_4429|M.thermoresistible__bu DFTRQGGGHGDITANDGPGYDSSGRLYSDTAALLDRTFTSLNAQLAAMRD MAV_0800|M.avium_104 DDAAAAGLDTARGNTIGPTPSSGGAGAGAGASGGGAPSAPADLNGPLTAD MAB_1796|M.abscessus_ATCC_1997 AAVGLPTSSISLPSGGGSVSALGFGGSSGSAGSSGASPK----QVREADD MLBr_01556|M.leprae_Br4923 LEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEG MSMEG_2146|M.smegmatis_MC2_155 GLDLLAP-------GASQAAQIGIKLANRAIGYAGQLAGIGVSGLMETFL Mvan_4360|M.vanbaalenii_PYR-1 SLDFLAP-------GAGAAANLGIQLANRTIGFVGQQVGNLWSGVAETFT Mb1121|M.bovis_AF2122/97 AGGGLGG-------GSFGLPGLNGSGGDGGDGGNGAPGGVLYG-----NG Rv1091|M.tuberculosis_H37Rv AGGGLGG-------GSFGLPGLNGSGGDGGDGGNGAPGGVLYG-----NG MMAR_1195|M.marinum_M DAGWLGN-------GGAGGTGGISRNGNGGDGGAGGSGGELLG-----VG MUL_3062|M.ulcerans_Agy99 NAGWLGS-------GGSGGAGGGS-NGDGGAGGTGGSGGQIVG-----DG Mflv_3843|M.gilvum_PYR-GCK YINYPAPPVPPTPPNSTGVSAGTPGSPAPGTPGSTLTLTDLLTPPGIART TH_4429|M.thermoresistible__bu QMVSVIEQVSHKLNDAALEPIVKAGVQSALEGLKDSVSHAIGTAMGQAAA MAV_0800|M.avium_104 QIAKLPPDQQLRLLRNAFAHPAPPAPAPAPAAPRPQPDADMLPAEVRAWA MAB_1796|M.abscessus_ATCC_1997 RINDLSN-----RLDVTEQELADLESNPKAKETTKQRKRDMVDKLKRDLQ MLBr_01556|M.leprae_Br4923 KATELAS-------REGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQL MSMEG_2146|M.smegmatis_MC2_155 PSGSP-LGNIGNSWFGKVASGFAG---------------ARPALPNTAG- Mvan_4360|M.vanbaalenii_PYR-1 LSGSGGAPDFMKSLPGRALAGIAG---------------ARPSMPNTAGG Mb1121|M.bovis_AF2122/97 GAGGQGSSGGIGGPGATGGAGGKG---------------GDGGDAQLIGD Rv1091|M.tuberculosis_H37Rv GAGGQGSSGGIGGPGATGGAGGKG---------------GDGGDAQLIGD MMAR_1195|M.marinum_M GAGGQG---GQANAGGGTGTGGEG---------------GDGGDAGLIGD MUL_3062|M.ulcerans_Agy99 GAGGAG---GQGDLLAAGGSGGDG---------------GQGGDAVLIGT Mflv_3843|M.gilvum_PYR-GCK LQNTASSVMGATPPGTPPVPGGSGSVS-----------LAVPGTPSPIAP TH_4429|M.thermoresistible__bu PPIADAVRQGMASLPIATSGGDSGGNA-----------FSGLIPGMASGG MAV_0800|M.avium_104 QQHGMIGPDGNYSGPALPNLGPKSVAPPVKMQPDLSRLGGNTKGPQPPGP MAB_1796|M.abscessus_ATCC_1997 QAKDDRNALGSSGSGGGFGGGNNPYAK------------IAEGLAEIMPD MLBr_01556|M.leprae_Br4923 GRAEIRALFRSSKVGIIAGCIISS---------------GVVRRNAKVRL MSMEG_2146|M.smegmatis_MC2_155 ----QQAPPNPNPAQPGQPGQQQPGQPINLEYH-------------NHQA Mvan_4360|M.vanbaalenii_PYR-1 GGQQPQADPRQQQGQQQGPNSGPMVEISGDIYQ-------------QPGQ Mb1121|M.bovis_AF2122/97 GGNGGNGGAGGTGGTPGPGGPGGSGGLGGLLFG-------------QTGT Rv1091|M.tuberculosis_H37Rv GGNGGNGGAGGTGGTPGPGGPGGSGGLGGLLFG-------------QTGT MMAR_1195|M.marinum_M GGNGGNAGTDTDGTPTGDPGTGGTG---GTLLG-------------ANGN MUL_3062|M.ulcerans_Agy99 GGNGGNG---ASGVLAGIGGDGGSR---GLLLG-------------EDGV Mflv_3843|M.gilvum_PYR-GCK LAATGLSNLVSPPSLTIPSIPGLPVPLPNTVPVPSDLLCVGTDWSASQGD TH_4429|M.thermoresistible__bu PVYGGVAGRDSVPALLMPGEHVLTTDDVARLGGQSGVYAFRAALARTGGV MAV_0800|M.avium_104 PSAPPTPWTESTRGQSWLHDPNAPSWDTGLNLPKLGNQARQFFDLRQPGY MAB_1796|M.abscessus_ATCC_1997 AGGLADIGIGGLKESLLPPGFSDPTQWGLVQAGSTLLKFFGGLRNNSDGK MLBr_01556|M.leprae_Br4923 LRDNIVVTDNLTVTSLRREKDDVTEVREGFECG------------MTLGY MSMEG_2146|M.smegmatis_MC2_155 TEDRAGA-------------DITRHLEVQNAPAGQR-------------- Mvan_4360|M.vanbaalenii_PYR-1 EPTSVAN-------------EISSQVRAAEFSSGWMNARGI--------- Mb1121|M.bovis_AF2122/97 AGVSP--------------------------------------------- Rv1091|M.tuberculosis_H37Rv AGVSP--------------------------------------------- MMAR_1195|M.marinum_M AGMG---------------------------------------------- MUL_3062|M.ulcerans_Agy99 NGEAAPP-------------MTHIVLLGGDFPAAAS-------------- Mflv_3843|M.gilvum_PYR-GCK SAATPPA-------------AEVPRVVTGAAPTGDRRDRWGNR------- TH_4429|M.thermoresistible__bu RGFATGG-------------AVVNDVVGAEFFGVSQIPIIGLVVNILIRV MAV_0800|M.avium_104 FATGGPSGTDTIPAWLSPHEYVEPSEAVDKYGPGFMDAIRQGRIDPTSVR MAB_1796|M.abscessus_ATCC_1997 PLLGEGG-------------ALFANIAGSAMTGSGSGIVDAIKTIIPAPF MLBr_01556|M.leprae_Br4923 SDIKEGD-------------VIESYELVEKQRA----------------- MSMEG_2146|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4360|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1121|M.bovis_AF2122/97 -------------------------------------------------- Rv1091|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1195|M.marinum_M -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK -------------------------------------------------- TH_4429|M.thermoresistible__bu LLSVLGVQIQARDTLLQMTDEFRQFRGDFQAFDASGRLLNDTSALVDRAQ MAV_0800|M.avium_104 YYAPGGEVTDQPEPPPQQQAPAQQPQNMVKAPGAPGGPAIEPPPGAPKPG MAB_1796|M.abscessus_ATCC_1997 GSMDAAQLQGAPGDINPVIAGAQIPGTGFGDMGSAFSSGSAGPAQGGNGA MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4360|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1121|M.bovis_AF2122/97 -------------------------------------------------- Rv1091|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1195|M.marinum_M -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK -------------------------------------------------- TH_4429|M.thermoresistible__bu SSEEMAAQERIRILKIVIEALIRYIIEK---VIVPIGKAVANAAISAGAS MAV_0800|M.avium_104 DNASIHEPTGPGAVSPGSKQGLSDTATPGADVQQPGTGQGALPGIGFSGG MAB_1796|M.abscessus_ATCC_1997 NVDQSINFNAPVGTGVDQAMQKSQSAQNQQWRQNFGTRTGPVG------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4360|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1121|M.bovis_AF2122/97 -------------------------------------------------- Rv1091|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1195|M.marinum_M -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK -------------------------------------------------- TH_4429|M.thermoresistible__bu AAGAAINTQAPGVGGIVSSLITAAGQAGVDIIADVGTDLALAISETVIAV MAV_0800|M.avium_104 IIGGLEGAATQAAAMGADMGTFGGAGGAVSSAMNIGFQELNRAAAYGAQD MAB_1796|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4360|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1121|M.bovis_AF2122/97 -------------------------------------------------- Rv1091|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1195|M.marinum_M -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK -------------------------------------------------- TH_4429|M.thermoresistible__bu VAEGLQSLFPDLMTTIFGGGLLSVLLDPIGNILGNTFGGLLGGITSLLAG MAV_0800|M.avium_104 VGIGVEGLLEALIPNSDATGADWSKTIPGRLLMGVTGVRPAGQQNTAGQT MAB_1796|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4360|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1121|M.bovis_AF2122/97 -------------------------------------------------- Rv1091|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1195|M.marinum_M -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK -------------------------------------------------- TH_4429|M.thermoresistible__bu LFGGAATLIPGLPFDRGGIAYGTGLMPKATIAPERVLSPRQTELFERMVA MAV_0800|M.avium_104 QQPFASNASSDQYANVGNTQPQAPIQIMGPVHVQANDPKQLHETSIRRWP MAB_1796|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- MSMEG_2146|M.smegmatis_MC2_155 ------------------------------------------ Mvan_4360|M.vanbaalenii_PYR-1 ------------------------------------------ Mb1121|M.bovis_AF2122/97 ------------------------------------------ Rv1091|M.tuberculosis_H37Rv ------------------------------------------ MMAR_1195|M.marinum_M ------------------------------------------ MUL_3062|M.ulcerans_Agy99 ------------------------------------------ Mflv_3843|M.gilvum_PYR-GCK ------------------------------------------ TH_4429|M.thermoresistible__bu ALERNPRAATGSTTIVDVGGITVAGGPEAGERVRAGLMELMH MAV_0800|M.avium_104 STTQPARSARRGAHRRHTQGEHVAERHHHPLRCRPARRR--- MAB_1796|M.abscessus_ATCC_1997 ------------------------------------------ MLBr_01556|M.leprae_Br4923 ------------------------------------------