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MAVELSSGYVSATVRFDGVNRGISKLFDNVQKQAVSAGKRTGSAYAKALADEAKTAADQVKKISETVAKS RDKEADAAGKLKVALEKLNEAREAGTKGSKLTALSEAHASAMRKQQAAASELAKDLDAVARAQKRASDAQ SAIDKSSKPIRNQVSKLLSGSSDAAGREGGLAGRRFGDSFSSALRTTGIVAAGTAVGNLAANAMTKAASL ATSGVSAVVTKGLDFEKTMNTLSGVTGASADVMQRFRDTAKALGNDMTLSNTSAADAAQAMTELAKAGFS VDESITAAKGTLQLAAAAQVSAGQAAEIQANALQAFGLKADYASKAADVLSNAANASSAEITDVAFALQA GGSVARQTGVSLEDTAASIALLANNGIKGSDAGTLLKSALLKLSAPSDQASGALQELGVSAFDAQGNFVG MEALFGQLQAASKRMTPEMYAMNTALAFGSDAARLAGVAAKDGAAGFDKMRDAMNQEGSASKLAAAQNQG LPGVIERLKNAAETLAITLFEKIQGPLSSIGDGLTGFTNKMQDAFENPAVSQAAGNIGSALSTIGTAFGN VLSAVGPSLVSGLSDAVNLIVRFKDFLIPLVAGLAAYKTVMLAITVATKAWAAVQALLNIALTANPIGLI IAAIAGLVAGIVVLYKRNETFRNIVQATWTAIKNVIGAVWGWLSTTVFPALKTAFTAIGTGAMWLWNNAI KPAWNGIKEVIGLAWEVASDLFANWKRAMDLLGQGALWLWNNAISPAWEGIKTAISAAWRFVSPILDKFS EGWDALKSGISGASSAIKDAVTSAFSGLAAVIKAPLKVLGTFLAAIPSEVFGFQIPGADKLNSWGKSLQG FAAGGMVRGAGTGTSDSILAWLSNGEGVVTAKGMKNGGAGIVAALNSGWVPSAAYLHDMMRAPGYAQGLN PGADYLRSLVMKMWPQIKDIGGRRAEDGFGEHSSGNAIDIMIPGWDTPQGKALGDAVAAFIAKNASALGL DGFIWRQQSYGYGGSLTSGKQMPDRGSSTQNHMDHVHVMLGKGRGAGAAAVGLPTSSISLPSGGGSVSAL GFGGSSGSAGSSGASPKQVREADDRINDLSNRLDVTEQELADLESNPKAKETTKQRKRDMVDKLKRDLQQ AKDDRNALGSSGSGGGFGGGNNPYAKIAEGLAEIMPDAGGLADIGIGGLKESLLPPGFSDPTQWGLVQAG STLLKFFGGLRNNSDGKPLLGEGGALFANIAGSAMTGSGSGIVDAIKTIIPAPFGSMDAAQLQGAPGDIN PVIAGAQIPGTGFGDMGSAFSSGSAGPAQGGNGANVDQSINFNAPVGTGVDQAMQKSQSAQNQQWRQNFG TRTGPVG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_1796 | - | - | 100% (1337) | bacteriophage tape measure protein |
M. abscessus ATCC 19977 | MAB_0233 | - | 0.0 | 83.22% (1335) | putative phage tail tape measure protein TMP |
M. abscessus ATCC 19977 | MAB_0198 | - | 5e-11 | 42.39% (92) | hypothetical protein MAB_0198 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0328 | - | 2e-12 | 33.93% (112) | hypothetical protein Mb0328 |
M. gilvum PYR-GCK | Mflv_3457 | - | 3e-14 | 33.80% (142) | hypothetical protein Mflv_3457 |
M. tuberculosis H37Rv | Rv0320 | - | 2e-12 | 33.93% (112) | hypothetical protein Rv0320 |
M. leprae Br4923 | - | - | - | - | - |
M. marinum M | MMAR_2569 | - | 1e-12 | 37.61% (117) | hypothetical protein MMAR_2569 |
M. avium 104 | MAV_0800 | - | 1e-24 | 21.29% (1301) | phage tail tape measure protein, family protein, core region |
M. smegmatis MC2 155 | MSMEG_2146 | - | 4e-17 | 24.33% (559) | gp15 protein |
M. thermoresistible (build 8) | TH_0208 | - | 4e-18 | 34.62% (182) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_3192 | - | 6e-13 | 36.21% (116) | hypothetical protein MUL_3192 |
M. vanbaalenii PYR-1 | Mvan_1457 | - | 1e-86 | 35.62% (612) | TP901 family phage tail tape measure protein |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 ---MAVELSSGYVSATVRFDGVNRGISKLFDNVQ-----------KQAVS Mvan_1457|M.vanbaalenii_PYR-1 ---MPITLKVEAQADNRSFKQAADQAERVFADAG-----------KAASG MSMEG_2146|M.smegmatis_MC2_155 ---MGIPIPVEPTLDERSATAVAKRAEKAFADAG-----------KNAGQ MAV_0800|M.avium_104 MATSRALVDHFARVGNDISHGLGGSLSKAFAAVDGTAARRELLALQQEWR MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 AGKRTGSAYAKALADEAKTAADQVKKISETV----------AKSRDKEAD Mvan_1457|M.vanbaalenii_PYR-1 SFAKAFGEGSKEVKQATSQAVKAYDAVADAVGKATVAEKQRQQAVAKSED MSMEG_2146|M.smegmatis_MC2_155 AFTGAFSDGARDADQAVKKVADRAS-----------------DAYDKARD MAV_0800|M.avium_104 RAADVEADAAARMIRDQRRLAEATVKYGDDSSRTAAAQAMLARSQRDHID MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 AAGKLKVALEKLNEAREAGTKGSKLTALSEAHASAMRKQQAAASELAKDL Mvan_1457|M.vanbaalenii_PYR-1 LAKKAAAAEKKLNSARDAGDTKAVASAEKELERVRDQQARTTMQVVRSAD MSMEG_2146|M.smegmatis_MC2_155 AAGRLRAEEEKLKRLRDEGASNDRIVAQAER----------VEKARRAEV MAV_0800|M.avium_104 AMIAAEAAHGRLAKAGNETADSVSRLQKLGANPIFNAAGIGSVAGVGIAM MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 DAVARAQKRASDAQSAIDKSSKPIRNQVSKLLSGSSDAAGREGGLAGRRF Mvan_1457|M.vanbaalenii_PYR-1 AASRARRQEQRETREAVQAYRELQNAQVRASQSGGSTRMAGGLLSGITSQ MSMEG_2146|M.smegmatis_MC2_155 RAVRDATDAYREYEQAAQSAGQNAGQNFAGGLRGSLSGIGAAGQDAANEF MAV_0800|M.avium_104 DLTTRKAGDLEQQLMKLHAAAGETGEMIGGQFSGNLKTISDGVLQMSGKV MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 GDSFSSALRTTGIVAAGTAVGNLAANAMT--------KAASLATSGVSAV Mvan_1457|M.vanbaalenii_PYR-1 SSGVVGQFTSLGGSAGKAFIGGAVAAIVAGGLVSAGAKAAGMVLDGFKSV MSMEG_2146|M.smegmatis_MC2_155 VGGFAGSSALLRLGSAGGPIGLALAGVATLGVMGGRLLANGIADG----- MAV_0800|M.avium_104 GYTTTELMNAMYTIEKAGFRGADALKVLDAAAQGAGSEQADLMEVVNGLT MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 VTKGLD------FEKTMNTLSGVTGASADVMQRFRDTAKALGNDMTLSNT Mvan_1457|M.vanbaalenii_PYR-1 LDTGID------FSKTVNSFQGVTESSPAQTERMAAAARALGADTTMAGV MSMEG_2146|M.smegmatis_MC2_155 -LQTLQ------VQDLIATRMGLDGATMNRFGNAAGQAYANGWGQSLEDN MAV_0800|M.avium_104 TSMTDFNVKPEQAARLMSQMVTAVGSAKTSFQDFAGALHSVEPVAAAAHL MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 SAADAAQAMTELAKAGFSVDESITAAKGTLQLAAAAQVSAGQAAEIQANA Mvan_1457|M.vanbaalenii_PYR-1 SASDAARAMTELAKAGFSVDEAISSARGTMQLATAAEIDAAEAAEIQANA MSMEG_2146|M.smegmatis_MC2_155 LRSLQFGVQSGLIGPDVNEADAQKFIERIQATSGVLEEDPQQIARGVRNF MAV_0800|M.avium_104 KLEDVWGTLAQLTQSGTSPEQATENMRNAINAFTGQSQPARDAMAQFGIN MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 LQAFGLKADYASKA-----------------ADVLSNAANASSAEITDVA Mvan_1457|M.vanbaalenii_PYR-1 INAFGLSADDAAHV-----------------ADVLANAAVGSAADIPDLA MSMEG_2146|M.smegmatis_MC2_155 VKTG--LVSDYEQA-----------------FDLIVASTQKGLNISNDLL MAV_0800|M.avium_104 ADEVSQKLSERGLAGTMQYLFDTVQSKLLPGMKLNQGELFKSSQAAADLD MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 FALQAGGSVARQTGVSLEDTAASIALLANNGIKGSDAG-------TLLKS Mvan_1457|M.vanbaalenii_PYR-1 LALQQVGGIAQGFGEDIEGTVAAIAMLADVGIKGSDAG-------TLLKT MSMEG_2146|M.smegmatis_MC2_155 DTFEEYG-----------------TKFRDLGINGQEAL-------GLINQ MAV_0800|M.avium_104 EMITQMSPHAAQLATALKNNEITVKDYTKAARDSVAEDRAKLMEFAQLND MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 ALLKLSAPSDQASGALQELGVSAFDAQG-NFVGMEALFGQLQAASKR--- Mvan_1457|M.vanbaalenii_PYR-1 TLQSITKQGDPARDAMEALGLSLYNLDTGQFVGFREMFRQLDEARAR--- MSMEG_2146|M.smegmatis_MC2_155 LWEGGARNVDVAADALKEFAITVVDNSDTTKTALTALGFDAEELGRK--- MAV_0800|M.avium_104 KVDGYSKALRTGRDTIETLGKAMRDMTGTVAGQSVALQVSGDHAQETNDR MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 ---MTPEMYAMNTALAFGSDAARLAGVAAKDGAAGFDKMRDAMNQEGSAS Mvan_1457|M.vanbaalenii_PYR-1 ---LRPQDFQAQTNILFGSDAMRSAMLG---TVADFDTMEATINRVGTAG MSMEG_2146|M.smegmatis_MC2_155 ---FAEGGPTAR---------------------AAFGAVLDALASVKDPM MAV_0800|M.avium_104 IKAIATTYTEADGTVKGFHESQDTLNAKMRDAHAAFGAAEAEIGSAFVPV MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 KLAAAQNQGLPGVIERLKNAAETLAITLFEKIQGPLS------SIGDGLT Mvan_1457|M.vanbaalenii_PYR-1 DMARAKMQGWPGIMEGINNTIGELKLSLFDDIFNTPAGQEFGNKIVESLD MSMEG_2146|M.smegmatis_MC2_155 EQERIGLDLFKTKWEDVGDAIKNLDLP----------------SAANELG MAV_0800|M.avium_104 MTEVAKDAKWVGDELAKHPGIAHGVITALEGLGGAWLTFKAIDIVGTILR MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 GFTNKM-QDAFENPAVSQAAGNIGSALS--------TIGTAFGNVLSAVG Mvan_1457|M.vanbaalenii_PYR-1 GLVEWVNTHKPEIIGFVAAIGSAGASIA--------DTFLMFGARIMDTG MSMEG_2146|M.smegmatis_MC2_155 NVAGKTDEATGALQRHADGWDTLGRNID--------ETFRKFKEWLADSA MAV_0800|M.avium_104 PIASGLGTIIAQEEGAEVATSRLSTALSGLKAAGILGIGAQLGGQWAQDH MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 PSLVSGLSDAVNLIVRFKDFLIPLVAGLAAYKTVMLAITVATKAWAAVQA Mvan_1457|M.vanbaalenii_PYR-1 ATMIDFVNMVFTSMIEGGSKTAQLFGGIIKHIPGFQSVGEGIEDMGAKFD MSMEG_2146|M.smegmatis_MC2_155 IG----------------------------------------TFFSQTLP MAV_0800|M.avium_104 TDPNSFLHSASVVGTDTATGAALGAAAGSIIPGVGTAIGAGVGAAGGFAV MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 LLNIALTANPIGLIIAAIAGLVAGIVVLYKRNETFRNIVQATWTA----- Mvan_1457|M.vanbaalenii_PYR-1 GWADKLQALPGQMRTAANGLDSFRDGIRGMRDDFVGSMGEMALAE----- MSMEG_2146|M.smegmatis_MC2_155 GFLNAPFEQPPPPPPPAPG----------------QSLGDSGIYG----- MAV_0800|M.avium_104 GLYNQLTSHAEGGPLHAPGPKGHDSALFWGADGEHVLTHQEVQKMGGHSE MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 ----------------------------------------------IKNV Mvan_1457|M.vanbaalenii_PYR-1 ----------------------------------------------QKNR MSMEG_2146|M.smegmatis_MC2_155 ----------------------------------------------PPVQ MAV_0800|M.avium_104 VYKFRSDLMNGRIVLGRAGGGALGYGGMAPDVAVASSLAGTPYSQGARDD MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 IGAVWGWLSTTVFPALKTAFTAIGTGAMWLWNNAIKPAWNGIKEVIGLAW Mvan_1457|M.vanbaalenii_PYR-1 FYAQSFKQIQSAVELIPETKQIVVADNSPEVKQKLIQLGFAVQTLPNGKL MSMEG_2146|M.smegmatis_MC2_155 GPGLNGDGVQVPSDSALPPFLTPGLTGPGLVDPRINAPIPAQPTIPLGPP MAV_0800|M.avium_104 CSGMVGRVILGAMGLPATNLPTTKNMGQWLAALGFQPGIGGPGSISVGWY MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 EVASDLFANWKRAMDLLGQGALWLWNNAISPAWEGIKTAISAAWRFVSPI Mvan_1457|M.vanbaalenii_PYR-1 VINVEYRDPSGKLVDPSQLGVSQRQLDDRDSRQHDWGIDPPAGPAPLGTQ MSMEG_2146|M.smegmatis_MC2_155 PPDSPERGPGMPYDQAQQQVADAGRTDSAKPSFDPSQYSVDAIPVPGAIP MAV_0800|M.avium_104 DHGPNPNDGHAAMTLSNGENAEAGGSHGNFVIGAGAAGAASSQFDQHMFL MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 LDKFSEGWDALKSG-----ISGASSAIKDAVTSAFSG------------L Mvan_1457|M.vanbaalenii_PYR-1 SIPAGGGSSSLPDAPVLPINYTNTAGMTAELASAQSR------------V MSMEG_2146|M.smegmatis_MC2_155 MPAVAGAPGAPMPGAGGGMGYYEVD--PQRVYDAETS------------V MAV_0800|M.avium_104 PTLYGEGAATGMPGFAAGMGAGGFGGMGGGIPPGATPGTGPGGQPGYYTA MMAR_2569|M.marinum_M -MGINVFGNGRGRWLAFAAS----------LALSAAMIYAQNAKP----- MUL_3192|M.ulcerans_Agy99 -MGINVFGNGRGRWLAFTAS----------LALSAAMIYAQNAKP----- Mflv_3457|M.gilvum_PYR-GCK -MGRNLLGNGRGRWLAVAVS----------VALSAAMVYAQHPES----- TH_0208|M.thermoresistible__bu --------------MAVPLA----------GLLSAAAGGHAHLDP----- Mb0328|M.bovis_AF2122/97 -MGRHELARDRRKSSAVLAA----------VLAPAAVFFATGGDVSTLAA Rv0320|M.tuberculosis_H37Rv -MGRHELARDRRKSSAVLAA----------VLAPAAVFFATGGDVSTLAA MAB_1796|M.abscessus_ATCC_1997 AAVIKAPLKVLGTFLAAIPS----------EVFGFQIPGADKLNSWGKSL Mvan_1457|M.vanbaalenii_PYR-1 DETRHTLAEKQARLNQLLES----------GVADEAEIQKARNDVAKAGQ MSMEG_2146|M.smegmatis_MC2_155 LSARNSVESARIRVLELEAE----------GNATAQQLATARQQVTMAER MAV_0800|M.avium_104 NPQRVAAAEERLRHLDAEIDNAEKRRSELKATAKQSERDRLDEEIRHLKA . MMAR_2569|M.marinum_M -----PCCVEP-PAAAPVSPASPAPAPVSAPHTA----SPVEAQSLAANA MUL_3192|M.ulcerans_Agy99 -----PCCVEP-PAAAPVSPVSPAPAPVSAPHTA----SPVEAQSLAANA Mflv_3457|M.gilvum_PYR-GCK -----PRAPHSVPEAAQATSRAPETASAPAPTEA----ELLAAN--AAAP TH_0208|M.thermoresistible__bu -----FPDSRD-ATGWNTELVATAPNGPSGTHYR----IPAADPPPLPAS Mb0328|M.bovis_AF2122/97 RADANPVLGDDAPCCVQIVPVAPLAFSSQISGGE----IGTGLAASQFAS Rv0320|M.tuberculosis_H37Rv RADANPVLGDDAPCCVQIVPVAPLAFSSQISGGE----IGTGLAASQFAS MAB_1796|M.abscessus_ATCC_1997 QGFAAGGMVRGAGTGTSDSILAWLSNGEGVVTAKGMKNGGAGIVAALNSG Mvan_1457|M.vanbaalenii_PYR-1 DANEAQMRFVDAQRKVSEKQSNQLKGATTDLNEFGAQLDSDFGISKGLAG MSMEG_2146|M.smegmatis_MC2_155 QYVSAQMRLSEAQQGTWKKMENAAKGFSKGMDDIGAALDNDLGISEGLPG MAV_0800|M.avium_104 ERTQEQQRLAEAERGTFHAMHGRRGAGGGENPFLPVPLADRFGLSKGLPG MMAR_2569|M.marinum_M PVAAQEFQFSLPSGVAPESGLQVKTIWAARAI---SVLFPQITTIGGFRQ MUL_3192|M.ulcerans_Agy99 PVAAQEFQFSLPSGVAPESGLQVKTIWAARAI---SVLFPQITTIGGFRQ Mflv_3457|M.gilvum_PYR-GCK PADARVFDFPLPKGITPEGGLQVHTIWVARAI---ATMFPEITTIGGYRQ TH_0208|M.thermoresistible__bu RAAHRIDPESLPPGVAPEAGLQVKTILAARAV---SALFPEIMQIGGVRP Mb0328|M.bovis_AF2122/97 ASRWRIVSRYLPVGVAPEQGLQVKTVLTARSI---SAAFPEIREIGGVRP Rv0320|M.tuberculosis_H37Rv ASRWRIVSRYLPVGVAPEQGLQVKTVLTARSI---SAAFPEIREIGGVRP MAB_1796|M.abscessus_ATCC_1997 WVPSAAYLHDMMRAPGYAQGLNPGADYLRSLV---MKMWPQIKDIGGRRA Mvan_1457|M.vanbaalenii_PYR-1 IADNLVRFLGALALAGPVAKLQQISDAAGDEG---SGLMGILASNGAFGP MSMEG_2146|M.smegmatis_MC2_155 LADNLVRFVASLAAAPLLGPLSAISAANPIQGG--HGILGILGAQGAFGP MAV_0800|M.avium_104 LAEWTVGFLEDLVLGPLETAAWAAIGQAPPGAGGAGGGFGGLGVPGGLGA : *. MMAR_2569|M.marinum_M DP------------------------------------------------ MUL_3192|M.ulcerans_Agy99 DP------------------------------------------------ Mflv_3457|M.gilvum_PYR-GCK DA------------------------------------------------ TH_0208|M.thermoresistible__bu DS------------------------------------------------ Mb0328|M.bovis_AF2122/97 DA------------------------------------------------ Rv0320|M.tuberculosis_H37Rv DA------------------------------------------------ MAB_1796|M.abscessus_ATCC_1997 EDG----------------------------------------------- Mvan_1457|M.vanbaalenii_PYR-1 QFMPGAGRGSSYVGTPYGSAGIPRGG------------------------ MSMEG_2146|M.smegmatis_MC2_155 QYT----------------------------------------------- MAV_0800|M.avium_104 ARFGFPNPAPLAAPPGAPGADDAAAAGLDTARGNTIGPTPSSGGAGAGAG MMAR_2569|M.marinum_M ---------------------------------LKWHPNGLAIDVMIPDH MUL_3192|M.ulcerans_Agy99 ---------------------------------LKWHPNGLAIDVMIPDH Mflv_3457|M.gilvum_PYR-GCK ---------------------------------LKWHPNGLAIDVMIPNH TH_0208|M.thermoresistible__bu ---------------------------------MRWHPNGLAIDVMIPDY Mb0328|M.bovis_AF2122/97 ---------------------------------LRWHPNGLALDVMVPNP Rv0320|M.tuberculosis_H37Rv ---------------------------------LRWHPNGLALDVMVPNP MAB_1796|M.abscessus_ATCC_1997 ---------------------------------FGEHSSGNAIDIMIPGW Mvan_1457|M.vanbaalenii_PYR-1 -------APTEDQVKQIAAAFGLQVTSEDRPGDPGYHGQGMALDVSNGSG MSMEG_2146|M.smegmatis_MC2_155 --------------------------------QSQYAQQGYGYPAGYAAG MAV_0800|M.avium_104 ASGGGAPSAPADLNGPLTADQIAKLPPDQQLRLLRNAFAHPAPPAPAPAP . MMAR_2569|M.marinum_M ASPEGIELGNQIAGYALANAKRWGVL--HVIWRQKIYPGIGAPS------ MUL_3192|M.ulcerans_Agy99 ASPEGIELGNQIAGYALANAKRWGVL--HVIWRQKIYPGIVAPS------ Mflv_3457|M.gilvum_PYR-GCK NSEAGIALGNQIAGYALANAERMGVI--HVIWRQGFYPGIGAPS------ TH_0208|M.thermoresistible__bu ASPEGRALGDEIVEFVLANGDRFGLD--HIIWRQTYYPRNGTPR------ Mb0328|M.bovis_AF2122/97 GTAEGIALGNEIVAFVLKNATRFGMQ--DVIWRGAYYTPNGART------ Rv0320|M.tuberculosis_H37Rv GTAEGIALGNEIVAFVLKNATRFGMQ--DVIWRGAYYTPNGART------ MAB_1796|M.abscessus_ATCC_1997 DTPQGKALGDAVAAFIAKNASALGLD--GFIWRQQSYGYGGSLTSGK--- Mvan_1457|M.vanbaalenii_PYR-1 NTPQMREFAEYMSTNFGSSLKELIYS--DGSFSGLIGDGKNVTG------ MSMEG_2146|M.smegmatis_MC2_155 GYPGDAALLANVPAGRYSQTGIADLT--QGIADCSSAVEDLVNLLD---- MAV_0800|M.avium_104 AAPRPQPDADMLPAEVRAWAQQHGMIGPDGNYSGPALPNLGPKSVAPPVK : MMAR_2569|M.marinum_M -------------WTADYGSETLNHYDHVHIATDGG--------GYPTGQ MUL_3192|M.ulcerans_Agy99 -------------WTADYGSETLNHYDHVHIATDGG--------GYPTGQ Mflv_3457|M.gilvum_PYR-GCK -------------WTADYGSETLNHFDHVHIATDGG--------GYPTGR TH_0208|M.thermoresistible__bu -------------PMADRGSDNANHYNHVHIATTGG--------GYPSGR Mb0328|M.bovis_AF2122/97 -------------TGAG-------HYDHIHITTVGG--------GYPTGE Rv0320|M.tuberculosis_H37Rv -------------TGAG-------HYDHIHITTVGG--------GYPTGE MAB_1796|M.abscessus_ATCC_1997 -------------QMPDRGSSTQNHMDHVHVMLGKGRGAGAAAVGLPTSS Mvan_1457|M.vanbaalenii_PYR-1 -------------TGYYDSGTLAEHQNHVHVAADWG-GSALQSSGGPVPV MSMEG_2146|M.smegmatis_MC2_155 --------------GRPTGGRSLSTHNADEWLRERG---FLPGAGGPGDF MAV_0800|M.avium_104 MQPDLSRLGGNTKGPQPPGPPSAPPTPWTESTRGQSWLHDPNAPSWDTGL . . . MMAR_2569|M.marinum_M ETYFIGSMKPTPRE------------------------------------ MUL_3192|M.ulcerans_Agy99 KTYFIGSMKPTPRE------------------------------------ Mflv_3457|M.gilvum_PYR-GCK ETYYIASMKR---------------------------------------- TH_0208|M.thermoresistible__bu T--FLR-------------------------------------------- Mb0328|M.bovis_AF2122/97 ELYIR--------------------------------------------- Rv0320|M.tuberculosis_H37Rv ELYIR--------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 ISLPSGGGSVSALGF--------------------GGSSGSAGSSGASPK Mvan_1457|M.vanbaalenii_PYR-1 NVVNGGSIAAPLTSA--------------------IGQWSADWNAIAQAE MSMEG_2146|M.smegmatis_MC2_155 RVGFNASHMQATLPG--------------------GTPFNWGSDSAAARR MAV_0800|M.avium_104 NLPKLGNQARQFFDLRQPGYFATGGPSGTDTIPAWLSPHEYVEPSEAVDK MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 QVR-----EADDRINDLSNRLDVTEQELADLESNPKAKETTKQRKRDMVD Mvan_1457|M.vanbaalenii_PYR-1 SGGNWSINTGNGYSGGLQFSPSSWAAAGGTQYAPSAYQASPYQQALTAER MSMEG_2146|M.smegmatis_MC2_155 GIGGTGADDPAFTSHYYRPAVAGSASVPTIPAAPSVTVYPSTASASPSTA MAV_0800|M.avium_104 YGPGFMDAIRQGRIDPTSVRYYAPGGEVTDQPEPPPQQQAPAQQPQNMVK MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 KLKRDLQQAKDDRNALGSSGSGGGFGGGNNPYAKIAEGLAEIMPDAGGLA Mvan_1457|M.vanbaalenii_PYR-1 LLAMQGPGAWPNTFVPGSTGPSPDAVGPAGPLPSFIPGGAAGGPLGTGFP MSMEG_2146|M.smegmatis_MC2_155 ADIYSPANTNPALNNPATPATTPSSLPPVSGGGGTLPFMGQGGPQAAPFA MAV_0800|M.avium_104 APGAPGGPAIEPPPGAPKPGDNASIHEPTGPGAVSPGSKQGLSDTATPGA MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 DIGIGGLKESLLPPGFSDPTQWGLVQAGSTLLKFFGGLRNNSDGK----- Mvan_1457|M.vanbaalenii_PYR-1 QGLPGLGGQAYPAQGGEGGVGMGGMAMDAAMLGTSALDMMAPGAG----- MSMEG_2146|M.smegmatis_MC2_155 LNTP-VGGSAFPAQGGGGFQGVSGLPMDAIMTATQGLDLLAPGAS----- MAV_0800|M.avium_104 DVQQPGTGQGALPGIGFSGGIIGGLEGAATQAAAMGADMGTFGGAGGAVS MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 PLLGEGGALFANIAGSAMTGSGSGIVDAIKTIIPA---PFGSMDAAQLQG Mvan_1457|M.vanbaalenii_PYR-1 AAAKVGIQLANRTIKYAGQVAGIGVSGLLETFSPAGDNPKASIGNSWLGK MSMEG_2146|M.smegmatis_MC2_155 QAAQIGIKLANRAIGYAGQLAGIGVSGLMETFLPSG-SPLGNIGNSWFGK MAV_0800|M.avium_104 SAMNIGFQELNRAAAYGAQDVGIGVEGLLEALIPNSDATGADWSKTIPGR MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 APGDINPVIAGAQIPGTGFGDMGSAFSSGSAGPAQGGNGANVDQSINFNA Mvan_1457|M.vanbaalenii_PYR-1 IMGGLAGAAPSLPNMAGGKKPDAINGGDAQAGGKAGGNTVSITNNLTNNH MSMEG_2146|M.smegmatis_MC2_155 VASGFAGARPALPNTAGQQAPPNPNPAQPGQ-PGQQQPGQPINLEYHNHQ MAV_0800|M.avium_104 LLMGVTGVRPAGQQNTAGQTQQPFASNASSDQYANVGNTQPQAPIQIMGP MMAR_2569|M.marinum_M -------------------------------------------------- MUL_3192|M.ulcerans_Agy99 -------------------------------------------------- Mflv_3457|M.gilvum_PYR-GCK -------------------------------------------------- TH_0208|M.thermoresistible__bu -------------------------------------------------- Mb0328|M.bovis_AF2122/97 -------------------------------------------------- Rv0320|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1796|M.abscessus_ATCC_1997 PVGTGVDQAMQKSQSAQNQQWRQNFGTRTGPVG----------------- Mvan_1457|M.vanbaalenii_PYR-1 ATEDMVGNQLVREQAAMYTQSGVQ-------------------------- MSMEG_2146|M.smegmatis_MC2_155 ATEDRAGADITRHLEVQNAPAGQR-------------------------- MAV_0800|M.avium_104 VHVQANDPKQLHETSIRRWPSTTQPARSARRGAHRRHTQGEHVAERHHHP MMAR_2569|M.marinum_M --------- MUL_3192|M.ulcerans_Agy99 --------- Mflv_3457|M.gilvum_PYR-GCK --------- TH_0208|M.thermoresistible__bu --------- Mb0328|M.bovis_AF2122/97 --------- Rv0320|M.tuberculosis_H37Rv --------- MAB_1796|M.abscessus_ATCC_1997 --------- Mvan_1457|M.vanbaalenii_PYR-1 --------- MSMEG_2146|M.smegmatis_MC2_155 --------- MAV_0800|M.avium_104 LRCRPARRR