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MAFVLAVPDMVAEAAADLAGVGSVIDAANTAAAGSTTGIVAAAEDEVSAAIAALFSGHGQAYQQISTRVA EFHAQFERVFAAGVQAYSGAEAANASFLQDPLQTALNATNKPVQDLTGRPLVGNGANGVPGTGANGAAGG WLLGNGGAGGSGAAGQAGGDGGAAGLIGAGGAGGAGGNSPLRNTANGGNGGTGGAGGLLFGPGGVGGAGG ASFLTGGTGGDGGAGGLFGAGGLGGVGGSGNVGGNGGAGGAGGLLAGLVGAGGGDGGSGGLGAAGGDGGN GGRAGLFGGAGGAGGMGATGGHSGGDGGAGGDAGLLFGTGGAGGAGGHAFDGDGGAGGAGGNAGLMFSSG GSGGVGGAGSIDGGAGGAGGDAGWLGGGGAGGAGGFGTISDGGAGGRGGGGGQLLGNGGAGGAGGQGGND GGAGGLGGNGVLIGNGGNGGVGGVGETPGGDGGGGISGLLLGADGFNAPAGSSPVHALQQQALAAINAPV QELTGRPLIGNGLPGSAGSGAAGAPGGWLLGDGGAGGSAAATPGAAGGAGGAAGLVGAGGAGGAGANTGI SNPGFGGAGGAGGAGAGAGGGVGEAGGAGGLLGAGGTGGGGGVAPSLVDGGTGGAGGAGGAGGLFGGIFG AGGGDGGAGGFTGGIDGAGGVGGAGGNTGLLGGPGGSGGSGGDGIAKLGFNVDGGAGGAGVNGGFLFGSG GTGGFGGVGGVGTSTGIGGAGGRGGNAGLLFSDAGVGGFGGFGGTGGNAGWLGSGGSGGAGGGSNGDGGA GGTGGSGGQIVGDGGAGGAGGQGDLLAAGGSGGDGGQGGDAVLIGTGGNGGNGASGVLAGIGGDGGSRGL LLGEDGVNGEAAPPMTHIVLLGGDFPAAAS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_3062 | - | - | 100% (870) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_2485 | - | 0.0 | 62.86% (754) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_4280 | - | 0.0 | 57.29% (789) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0767 | PE_PGRS9 | 0.0 | 61.15% (870) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-141 | 45.25% (811) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv0746 | PE_PGRS9 | 0.0 | 60.83% (840) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 2e-10 | 38.04% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 9e-42 | 33.33% (468) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_2695 | - | 0.0 | 95.41% (893) | PE-PGRS family protein, PE_PGRS9_1 |
M. avium 104 | MAV_4827 | - | 4e-23 | 40.76% (184) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-122 | 38.84% (865) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 4e-42 | 39.63% (328) | PUTATIVE - |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-141 | 44.15% (804) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment MUL_3062|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2695|M.marinum_M -------------------------------------------------- Mb0767|M.bovis_AF2122/97 -------------------------------------------------- Rv0746|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 ------------------MAFVLAVPDMVAEAAADLAGVGS--------- MMAR_2695|M.marinum_M ------------------MAFVLAVPDMVAGAAADLAGVGS--------- Mb0767|M.bovis_AF2122/97 ------------------MSFVLAMPEVLGSAATDLAALGS--------- Rv0746|M.tuberculosis_H37Rv ------------------MSFVLAMPEVLGSAATDLAALGS--------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------MSIIDFILNLFRDPVEAASYVADPEAALANAG------- MAV_4827|M.avium_104 ------------------MNIVLGVSMAPSSIQMVVLEGEYADG------ MUL_3062|M.ulcerans_Agy99 -----------------------------------VIDAANTAAAGSTTG MMAR_2695|M.marinum_M -----------------------------------VIDAANTAAAGSTTG Mb0767|M.bovis_AF2122/97 -----------------------------------VLGAADAAAAATTTG Rv0746|M.tuberculosis_H37Rv -----------------------------------VLGAADAAAAATTTG Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------LSAVSAAQVGAVMP MAV_4827|M.avium_104 ----------------------------------ATVEEDAIDVTGADDA MUL_3062|M.ulcerans_Agy99 IVAAAEDEVSAAIAALFSGHGQAYQQISTRVAEFHAQFERVFAAGVQAYS MMAR_2695|M.marinum_M IVAAAEDEVSAAIAALFSGHGQAYQQISARVAEFHAQFERVLAAGAQAYS Mb0767|M.bovis_AF2122/97 IVAAVQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAYA Rv0746|M.tuberculosis_H37Rv IVAAAQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAYA Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLS MAV_4827|M.avium_104 ATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAAR MUL_3062|M.ulcerans_Agy99 G------------------------AEAANASFLQDPLQTALN----ATN MMAR_2695|M.marinum_M G------------------------AEAANASFLQDPLQTALN----AIN Mb0767|M.bovis_AF2122/97 S------------------------AEAAGAAVLANPAQSVQQDLLAAVN Rv0746|M.tuberculosis_H37Rv S------------------------AEAAGAAVLANPAQSVQQDLLAAVN Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 P---------------------------RDNDFLSHNDTDFASHNPIASG MAV_4827|M.avium_104 R------------------------------------------IDNVMLV MUL_3062|M.ulcerans_Agy99 KPVQDLTGRPLVGNGANGVPG-----TGANGAAGGWLLGNGGAGGSGAAG MMAR_2695|M.marinum_M TPVQDLTGRPLVGNGANGVPG-----TGANGAAGGWLLGNGGAGGSGAAG Mb0767|M.bovis_AF2122/97 AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG Rv0746|M.tuberculosis_H37Rv AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_3810|M.thermoresistible__bu ------------------------------------------------VD MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 NQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP MAV_4827|M.avium_104 SAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQ MUL_3062|M.ulcerans_Agy99 --QAGGDGGAAGLIGAGGAGGAGGNSPLRNTANGGNGG--TGGAGGLLFG MMAR_2695|M.marinum_M --QAGGDGGAAGLIGAGGAGGAGGNSPLGNTANGGNGG--TGGAGGLLFG Mb0767|M.bovis_AF2122/97 SGLPGGAGGAAGLFGTGGAGGAGGSSTVG---DGGAGG--AGGSGGWLLG Rv0746|M.tuberculosis_H37Rv SGLPGGAGGAAGLFGTGGAGGAGGSSTVG---DGEAGG--AGGSGGWLLG Mflv_5091|M.gilvum_PYR-GCK --GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA Mvan_1264|M.vanbaalenii_PYR-1 --GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA MSMEG_0868|M.smegmatis_MC2_155 --LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG TH_3810|M.thermoresistible__bu --GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 IASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSA MAV_4827|M.avium_104 QIRAESYGDAAGQLSAMVAGLEKLESLPG-----------GLLLVGSGVD MUL_3062|M.ulcerans_Agy99 PGGVGGAGGASFLTGGTGGDGGAGGLFGAGGLGGVGG------------- MMAR_2695|M.marinum_M PGGVGGAGGASFLTGGTGGDGGAGGLFGAGGLGGVGG------------- Mb0767|M.bovis_AF2122/97 TGGVGGVGGLGAGAGGAGGVGGAGGLLGAGGHGGAGG------------- Rv0746|M.tuberculosis_H37Rv TGGVGGVGGLGAGAGGAGGVGGAGGLLGAGGHGGAGG------------- Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG------------- Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG------------- MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN TH_3810|M.thermoresistible__bu TGIIS--------------------LLSLAGNGGNGG------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 DIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTN----------- MAV_4827|M.avium_104 VAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAP------------ MUL_3062|M.ulcerans_Agy99 ---SGNVGG-NGGAGGAGGLLAGLVGAGGGDGGSGGLGAAGGDGGNGGRA MMAR_2695|M.marinum_M ---SGNVGG-NGGAGGAGGLLAGLVGAGGGDGGSGGLGAAGGDGGNGGRA Mb0767|M.bovis_AF2122/97 ---LGAVTGGVGGAGGAGGLLAGLLAGPGGAGGTGGRGFLN--------- Rv0746|M.tuberculosis_H37Rv ---LGAVTGGVGGTGGAGGLLAGLLAGPGGAGGTGGRGFLN--------- Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG-------------- Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG-------------- MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD TH_3810|M.thermoresistible__bu --NGYRTTDNNALDGGHGG------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 TEIGSHNQANIGTSTSAGG--SAAVGGNAGLAGNAG-------------- MAV_4827|M.avium_104 LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPE-------------- MUL_3062|M.ulcerans_Agy99 GLFGGAGGAGGMGATGGHSGGDGGAGGDAGLLFG-----------TGGAG MMAR_2695|M.marinum_M GLFGGAGGAGGMGATGGHSGGDGGAGGDAGLLFG-----------TGGAG Mb0767|M.bovis_AF2122/97 ------------------DGGVGGAGGNAGLLFG-----------AGGTG Rv0746|M.tuberculosis_H37Rv ------------------NGGVGGAGGNAGLLFG-----------AGGTG Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG TH_3810|M.thermoresistible__bu --------------------------------------------NGGNVG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------LAGNAG MAV_4827|M.avium_104 ----------------------------------------------PGDD MUL_3062|M.ulcerans_Agy99 GAGGHAFDGDGGAG----------------GAGGNAGLMFSSGGSGGVGG MMAR_2695|M.marinum_M GAGGHAFDGDGGAG----------------GAGGNAGLMFSSGGSGGVGG Mb0767|M.bovis_AF2122/97 GSGGAGLGGDGGAG----------------GAGGNAGVLFGNAGSGGTGG Rv0746|M.tuberculosis_H37Rv GSGGAGLGGDGGAG----------------GAGGNTGVLFGNAGSGGTGG Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE TH_3810|M.thermoresistible__bu FFSLFNLGG--------------------AGGWGGSGVDG---------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAG-------------NAGLAGNAGLAGNAGLAGNAGL MAV_4827|M.avium_104 ELAYSAVGEEDAES--------------------PTVVIEKLFLPEDSEP MUL_3062|M.ulcerans_Agy99 AG----SIDGGAGGAGGDAGWLGGGGAGGAGG------------------ MMAR_2695|M.marinum_M AG----SIDGGAGGAGGDAGWLGGGGAGGAGG------------------ Mb0767|M.bovis_AF2122/97 FG----DTDGGAGGAGGDAGWLGSGGVGGAGG------------------ Rv0746|M.tuberculosis_H37Rv FG----DTDGGAGGAGGDAGWLGSGGVGGAGG------------------ Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG--------- Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG--------- MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG TH_3810|M.thermoresistible__bu -----------VDVVGGNP------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AG---NAGLAGNAGLAGNAGLAGNAGLAGNAG------------------ MAV_4827|M.avium_104 RRRPVLLVGSGLAVVGISAVLALEIALAIGIR------------------ MUL_3062|M.ulcerans_Agy99 ------FGTISDGGAGGRGGGGGQLLG---------------------NG MMAR_2695|M.marinum_M ------FGTISDGGAGGRGGVGGQLLG---------------------NG Mb0767|M.bovis_AF2122/97 ------FGETGDGGVGGAGGKAGLLIG---------------------NG Rv0746|M.tuberculosis_H37Rv ------FGETGDGGVGGAGGKAGLLIG---------------------NG Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG TH_3810|M.thermoresistible__bu -----------DGGTPG------------------------------AHG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------LAGNAGLAGNAGLAGN-------------------------A MAV_4827|M.avium_104 --------TTGTVALQPTPNQHLIVP----------------------TE MUL_3062|M.ulcerans_Agy99 GAGGAGGQGGNDGGAGGLGGNG---------------------------- MMAR_2695|M.marinum_M GAGGAGGQGGNDGGAGGLGGNG---------------------------- Mb0767|M.bovis_AF2122/97 GAGGAG-------------------------------------------- Rv0746|M.tuberculosis_H37Rv GAGGAGGQGAVTGGTGGAGGDG---------------------------- Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD--------- Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN--------- MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN TH_3810|M.thermoresistible__bu ESHTPGVYTDRQ-------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGN--------------------------------- MAV_4827|M.avium_104 QAPAPPPVQASAPQPK---------------------------------- MUL_3062|M.ulcerans_Agy99 -----------VLIGNGGNGGVGGVGETPGGDGGGGISGLLLGADG---- MMAR_2695|M.marinum_M -----------VLIGNGGNGGVGGVGETPGGDGGGGISGLLLGADG---- Mb0767|M.bovis_AF2122/97 -----------VLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGADG---- Rv0746|M.tuberculosis_H37Rv -----------VLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGADG---- Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGAGGTGG-TGGAGGTGG------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGNGGTGG-TGGNGGTGG------------- MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST TH_3810|M.thermoresistible__bu -----------------GEDGEDGTGTGIGGRGGNGG------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------AGLAGNAGLAGNAAVAGNAAVAGN------------- MAV_4827|M.avium_104 ------------ISVPEPVAAPKPLSPPVAAPLPAAP------------- MUL_3062|M.ulcerans_Agy99 -FNAPAGSSPVHALQQQALAAINAPVQELTGRPLIGNGLPGSAGSGAAGA MMAR_2695|M.marinum_M -FNAPASSSPVHALQQQALAAINAPVQELTGRPLIGNGLPGSAGSGVAGA Mb0767|M.bovis_AF2122/97 -FNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVGSGATGA Rv0746|M.tuberculosis_H37Rv -FNTPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVGSGATGA Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGG TH_3810|M.thermoresistible__bu ---SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --AAVAGNAAVGGVLNTGVSGAIGGSSHVGG--AINESLGGSGSVGGSTA MAV_4827|M.avium_104 ----PPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPP MUL_3062|M.ulcerans_Agy99 PGG--WLLGDGGAGGS--AAATPGAAGGAGGAAG---------LVGAGGA MMAR_2695|M.marinum_M PGG--WLLGDGGAGGS--AAATPGAAGGAGGAAG---------LVGAGGA Mb0767|M.bovis_AF2122/97 PGG--WLLGDGGAGGS--GAAGSGAPGGAGGAAG---------LWGTGGA Rv0746|M.tuberculosis_H37Rv PGG--WLLGDGGAGGS--GAAGSGAPGGAGGAAG---------LWGTGGA Mflv_5091|M.gilvum_PYR-GCK KGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 KGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGT MSMEG_0868|M.smegmatis_MC2_155 RGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGN TH_3810|M.thermoresistible__bu HGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VGGGAHTGVGGGVSTG----VGVGSHVGGGISES---------LGGSGSV MAV_4827|M.avium_104 QLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQ-------SPPQHQTP MUL_3062|M.ulcerans_Agy99 GGAGANT----GISNPGFG----------------GAGGAGG-------- MMAR_2695|M.marinum_M GGAGANT----GISNPGFGGAGGDGGAGGFLLGDGGAGGAGG-------- Mb0767|M.bovis_AF2122/97 G------------------------GAGGWLLGDGGAGGIGG-------- Rv0746|M.tuberculosis_H37Rv GGAGG--------SSAGGGGAGGAGGAGGWLLGDGGAGGIGG-------- Mflv_5091|M.gilvum_PYR-GCK GGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-------- Mvan_1264|M.vanbaalenii_PYR-1 GGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG-------- MSMEG_0868|M.smegmatis_MC2_155 GGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATV TH_3810|M.thermoresistible__bu GGDG---------------GNGGSAG------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGSTAVG------------------------------------------- MAV_4827|M.avium_104 PGEGTPP------------------------------------------- MUL_3062|M.ulcerans_Agy99 -AGAGAGGGVGEAGGAGGLLGAGGTGG----------------------- MMAR_2695|M.marinum_M -AGAGAGGGVGGAGGAGGLLGAGGTGG----------------------- Mb0767|M.bovis_AF2122/97 -ASTVLGG-TGGGGGVGGLWGAGGAGG----------------------- Rv0746|M.tuberculosis_H37Rv -ASTVLGG-TGGGGGVGGLWGAGGAGG----------------------- Mflv_5091|M.gilvum_PYR-GCK ---------TGGTGGQGG-LGGGGGTG----------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------TGGTGGQGG-LGGVGGTG----------------------- MSMEG_0868|M.smegmatis_MC2_155 IGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATD TH_3810|M.thermoresistible__bu ---------RGGTGGLRGVFGINGGNG----------------------- MLBr_01183|M.leprae_Br4923 ---------------MPLFLNAEPQAL----------------------- MAB_4284c|M.abscessus_ATCC_199 ---------GGAHTGVGGGVSTGVGVG----------------------- MAV_4827|M.avium_104 --------KPDGPGNYGGGHVPTPGAG----------------------- MUL_3062|M.ulcerans_Agy99 -GGGVAPSLVDGGTGGAGGAGGAG------------GLFGGIFGAGGGDG MMAR_2695|M.marinum_M -GGGVAPSLVDGGTGGAGGAGGAG------------GLFGGIFGAGGGDG Mb0767|M.bovis_AF2122/97 -AGGTG---LVGGDGGAGGAGGTG------------GLLAGLIGAGGGHG Rv0746|M.tuberculosis_H37Rv -AGGTG---LVGGDGGAGGAGGTG------------GLLAGLIGAGGGHG Mflv_5091|M.gilvum_PYR-GCK GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFG Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFG MSMEG_0868|M.smegmatis_MC2_155 GHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNG TH_3810|M.thermoresistible__bu -RAGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGGGTP MLBr_01183|M.leprae_Br4923 ---TAAANTLEGLSAATVASNAAA---------------AQLTTEIAPPA MAB_4284c|M.abscessus_ATCC_199 SHVGGGISESLGGSGSVGGSTAVG---------------GGAHTGVGGGV MAV_4827|M.avium_104 --GSGGSGGGHVPTPGAGGSGGSG----------------GGHVPTPGTG . . . MUL_3062|M.ulcerans_Agy99 GAGGFTGGIDGAGGVGGAGGNTGLLGGPGGSGGSGGDGIAKLGFNVD-GG MMAR_2695|M.marinum_M GAGGFTGGIDGAGGVGGAGGNAGLLGGPGGSGGSGGDGIAKLGLNAD-GG Mb0767|M.bovis_AF2122/97 GTGGLN--TNGDGGVGGAGGNAGMLAGPGGAGGAGGD-----GENLDTGG Rv0746|M.tuberculosis_H37Rv GTGGLS--TNGDGGVGGAGGNAGMLAGPGGAGGAGGD-----GENLDTGG Mflv_5091|M.gilvum_PYR-GCK GSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAG Mvan_1264|M.vanbaalenii_PYR-1 GVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAG MSMEG_0868|M.smegmatis_MC2_155 GDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGS TH_3810|M.thermoresistible__bu SAGFGVPTTIQFPAGSCTSRAVSREG------------------------ MLBr_01183|M.leprae_Br4923 ADDVSILLAHFFSGHGRQYQAHASQG------------------------ MAB_4284c|M.abscessus_ATCC_199 NTGVGVGSHVGGGISESLGGSGSVGG------------------STAVGG MAV_4827|M.avium_104 GPGGTGGSGGGHVPTPGAGTPGGSGG-----------------------G . . . MUL_3062|M.ulcerans_Agy99 AGGAGVNGGFLFGSGGTGGFGGVGGVG---------TSTGIGGAGGRGGN MMAR_2695|M.marinum_M AGGAGGNGGFLFGSGGTGGFGGVGGVG---------TSTGIGGAGGRGGN Mb0767|M.bovis_AF2122/97 DGGAGGSAGLLFGSGGAGGAGGFG---------------FLGGDGGAGGN Rv0746|M.tuberculosis_H37Rv DGGAGGSAGLLFGSGGAGGAGGFG---------------FLGGDGGAGGN Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGA Mvan_1264|M.vanbaalenii_PYR-1 TAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGS MSMEG_0868|M.smegmatis_MC2_155 TLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGD TH_3810|M.thermoresistible__bu IMPSSRAASARAG---------------------------AACASSTSRS MLBr_01183|M.leprae_Br4923 ---ATNHQDLIQS--------------------------LLTSSSAYAGT MAB_4284c|M.abscessus_ATCC_199 GAHTSAINDALGGSGSVGGSTAVG-----------------GGAHTSAIN MAV_4827|M.avium_104 HLPFPGAGSTPGGSGGGHLPTPGAGTP-------------GGGLGGFGGG . MUL_3062|M.ulcerans_Agy99 AGLLFSDAGVGGFGGFGGTGG-------NAGWLGSGGSGGAGG-GSNGDG MMAR_2695|M.marinum_M AGLLFSDAGVGGFGGFGGTGGGTGGTGGNAGWLGSGGSGGAGG-GSNGDG Mb0767|M.bovis_AF2122/97 AGLLLSSGGAGGFGGFGTAGG-VGGAGGNAGWLGFGGAGGIGGIGGNANG Rv0746|M.tuberculosis_H37Rv AGLLLSSGGAGGFGGFGTAGG-VGGAGGNAGWLGFGGAG----------- Mflv_5091|M.gilvum_PYR-GCK TGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAG Mvan_1264|M.vanbaalenii_PYR-1 AGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAG MSMEG_0868|M.smegmatis_MC2_155 GGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADG TH_3810|M.thermoresistible__bu RRSFCCSRA----------------------------------------- MLBr_01183|M.leprae_Br4923 ETANHDSL------------------------------------------ MAB_4284c|M.abscessus_ATCC_199 ESMNSSINAS---------------------------------------- MAV_4827|M.avium_104 HAPAPGGGLGGGGG------------------------------------ MUL_3062|M.ulcerans_Agy99 GAGGTGGSGGQIVGDGGAGGAGGQGDLLAAGGSGGDGGQGGDAVLIG--- MMAR_2695|M.marinum_M GAGGTGGSGGQIVGDGGAGGAGGQGDLLAAGGSGGDGGQGGDAVLIG--- Mb0767|M.bovis_AF2122/97 GAGGNGGTGGQLWGSGGAGGEGGAA--LSVGDTGGAGGVGGSAGLIG--- Rv0746|M.tuberculosis_H37Rv -------------------------------------GVGGSAGLIG--- Mflv_5091|M.gilvum_PYR-GCK KAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG----- Mvan_1264|M.vanbaalenii_PYR-1 KAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG----- MSMEG_0868|M.smegmatis_MC2_155 WVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVW TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3062|M.ulcerans_Agy99 ------------TGGNGGNGASGVLAGIGGDGGSRGLLLGEDGVNGEAAP MMAR_2695|M.marinum_M ------------TGGNGGNGASGVLAGIGGDAGSGGLLLGEDGINGEAAP Mb0767|M.bovis_AF2122/97 ------------TGGNGGNGGTGANAGSPGTGGAGGLLLGQNGLNGLP-- Rv0746|M.tuberculosis_H37Rv ------------TGGNGGNGGTGANAGSPGTGGAGGLLLGQNGLNGLP-- Mflv_5091|M.gilvum_PYR-GCK ------AGGEGGEGGDGGKGGAGAEGGAGGGGGAGGSGAGGAG------- Mvan_1264|M.vanbaalenii_PYR-1 ------AGGEGGEGGAGGAGGDGSEGGAGGSGGAGGSGTGGAG------- MSMEG_0868|M.smegmatis_MC2_155 KSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGS TH_3810|M.thermoresistible__bu -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------HSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETA MAV_4827|M.avium_104 -------------HAPAPGGGLGGFGGGHSGGGLGGLGGGHK-------- MUL_3062|M.ulcerans_Agy99 PMTHIVLLGGDFPAAAS------------ MMAR_2695|M.marinum_M PMTHIVLLGGDFPAAAS------------ Mb0767|M.bovis_AF2122/97 ----------------------------- Rv0746|M.tuberculosis_H37Rv ----------------------------- Mflv_5091|M.gilvum_PYR-GCK GAGGSGGSGGSGGSGGSGGAAGDSDD--- Mvan_1264|M.vanbaalenii_PYR-1 GAGGSGGSGGSGGAGGSGGAAGDSD---- MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGGNGGADGTPGTAGTTGANNP TH_3810|M.thermoresistible__bu ----------------------------- MLBr_01183|M.leprae_Br4923 ----------------------------- MAB_4284c|M.abscessus_ATCC_199 HTTLPGAEHH------------------- MAV_4827|M.avium_104 -----------------------------