For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VGIPIPVEPTLDERSATAVAKRAEKAFADAGKNAGQAFTGAFSDGARDADQAVKKVADRASDAYDKARDA AGRLRAEEEKLKRLRDEGASNDRIVAQAERVEKARRAEVRAVRDATDAYREYEQAAQSAGQNAGQNFAGG LRGSLSGIGAAGQDAANEFVGGFAGSSALLRLGSAGGPIGLALAGVATLGVMGGRLLANGIADGLQTLQV QDLIATRMGLDGATMNRFGNAAGQAYANGWGQSLEDNLRSLQFGVQSGLIGPDVNEADAQKFIERIQATS GVLEEDPQQIARGVRNFVKTGLVSDYEQAFDLIVASTQKGLNISNDLLDTFEEYGTKFRDLGINGQEALG LINQLWEGGARNVDVAADALKEFAITVVDNSDTTKTALTALGFDAEELGRKFAEGGPTARAAFGAVLDAL ASVKDPMEQERIGLDLFKTKWEDVGDAIKNLDLPSAANELGNVAGKTDEATGALQRHADGWDTLGRNIDE TFRKFKEWLADSAIGTFFSQTLPGFLNAPFEQPPPPPPPAPGQSLGDSGIYGPPVQGPGLNGDGVQVPSD SALPPFLTPGLTGPGLVDPRINAPIPAQPTIPLGPPPPDSPERGPGMPYDQAQQQVADAGRTDSAKPSFD PSQYSVDAIPVPGAIPMPAVAGAPGAPMPGAGGGMGYYEVDPQRVYDAETSVLSARNSVESARIRVLELE AEGNATAQQLATARQQVTMAERQYVSAQMRLSEAQQGTWKKMENAAKGFSKGMDDIGAALDNDLGISEGL PGLADNLVRFVASLAAAPLLGPLSAISAANPIQGGHGILGILGAQGAFGPQYTQSQYAQQGYGYPAGYAA GGYPGDAALLANVPAGRYSQTGIADLTQGIADCSSAVEDLVNLLDGRPTGGRSLSTHNADEWLRERGFLP GAGGPGDFRVGFNASHMQATLPGGTPFNWGSDSAAARRGIGGTGADDPAFTSHYYRPAVAGSASVPTIPA APSVTVYPSTASASPSTAADIYSPANTNPALNNPATPATTPSSLPPVSGGGGTLPFMGQGGPQAAPFALN TPVGGSAFPAQGGGGFQGVSGLPMDAIMTATQGLDLLAPGASQAAQIGIKLANRAIGYAGQLAGIGVSGL METFLPSGSPLGNIGNSWFGKVASGFAGARPALPNTAGQQAPPNPNPAQPGQPGQQQPGQPINLEYHNHQ ATEDRAGADITRHLEVQNAPAGQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2146 | - | - | 100% (1214) | gp15 protein |
| M. smegmatis MC2 155 | MSMEG_3499 | - | 4e-14 | 33.33% (177) | hypothetical protein MSMEG_3499 |
| M. smegmatis MC2 155 | MSMEG_0076 | - | 5e-07 | 24.21% (413) | antigen MTB48 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1145 | - | 3e-11 | 30.41% (171) | hypothetical protein Mb1145 |
| M. gilvum PYR-GCK | Mflv_3272 | - | 2e-12 | 30.97% (155) | hypothetical protein Mflv_3272 |
| M. tuberculosis H37Rv | Rv1115 | - | 4e-11 | 30.41% (171) | hypothetical protein Rv1115 |
| M. leprae Br4923 | MLBr_00048 | - | 1e-05 | 25.11% (219) | hypothetical protein MLBr_00048 |
| M. abscessus ATCC 19977 | MAB_0233 | - | 2e-18 | 24.07% (536) | putative phage tail tape measure protein TMP |
| M. marinum M | MMAR_5451 | - | 1e-07 | 32.67% (150) | hypothetical protein MMAR_5451 |
| M. avium 104 | MAV_0800 | - | 2e-15 | 31.23% (269) | phage tail tape measure protein, family protein, core region |
| M. thermoresistible (build 8) | TH_2084 | - | 3e-07 | 28.57% (147) | Erp protein |
| M. ulcerans Agy99 | MUL_3507 | - | 1e-07 | 24.25% (433) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_4360 | - | 0.0 | 38.26% (1218) | Phage-related minor tail protein-like |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2146|M.smegmatis_MC2_155 ----------------------MGIPIPVEPTLDERSATAVAKRAEKAFA
Mvan_4360|M.vanbaalenii_PYR-1 -----------------------MVTMVVGTEIDDNSLRQSANDIQRRFD
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 MATSRALVDHFARVGNDISHGLGGSLSKAFAAVDGTAARRELLALQQEWR
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 ----------------MAVELASGYVSLSVRVGATSGLGKLFDNAQKQAT
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 DAGKNAGQAFTGAFSDGARDADQAVKKVADRAS-----------------
Mvan_4360|M.vanbaalenii_PYR-1 RLGQNVGGDFMTQFADGAAANAPKVQKAVD--------------------
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 RAADVEADAAARMIRDQRRLAEATVKYGDDSSRTAAAQAMLARSQRDHID
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 SAGKKTGEAFAKALASEAKAAEEQVKKLTDTVTK----------------
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 ------DAYDKARDAAGRLRAEEEKLKRLRDEGASNDRIVAQAERVEKAR
Mvan_4360|M.vanbaalenii_PYR-1 ----------KAADATGRLRSEQEKLDALTANGASRDRIVTQSEKVAKAR
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 AMIAAEAAHGRLAKAGNETADSVSRLQKLGANPIFNAAGIGSVAGVGIAM
MLBr_00048|M.leprae_Br4923 -----------------MAADYDKLFRLDDGAYASPDQAAEQLFDDAPLY
MMAR_5451|M.marinum_M -----------------MPADYDELFQPAEGSGPPDDETGQTFFDPGTAY
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 -------SRDKEADQAGKLKVALEKLNEARQGGVSGSKLTALEESHAAAL
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 RAEVRAVRDATDAYREYEQAAQSAGQNAGQNFAGGLRGSLSGIGAAGQDA
Mvan_4360|M.vanbaalenii_PYR-1 RDEARAYREATAAVEDYDRAGQRAGN----SFTSGLRSGEAGAAEAGGGF
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 DLTTRKAGDLEQQLMKLHAAAGETGEMIGGQFSGNLKTISDGVLQMSGKV
MLBr_00048|M.leprae_Br4923 PPPIIP------------------------TCTTTPNGEVASPMP-----
MMAR_5451|M.marinum_M PPPVKPNGDGHSAPKDWSRAFPPAEDESPSDSAEPAAGPAKSPLPP----
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 RKQQAAAQDLAKDLDAVTRAQRRATDAQAAVGRAPKNVQNRVSQLLSGSA
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 ANEFVG-----------GFAGSSALLRLGSAGGPIGLALAGVATLGVMGG
Mvan_4360|M.vanbaalenii_PYR-1 ADSFAG-----------GFAGASSLSGLGGG----LLKAGGWITAGIAAG
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 GYTTTELMNAMYTIEKAGFRGADALKVLDAAAQGAGSEQADLMEVVNGLT
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M ------------------------------------MPIGGPAPTPPEPP
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 DAAGHAGGLAGRRFGDSFSGALRSTGIVAAGTAVGNLAANAMTKAASFAT
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 RLLANGIADGLQTLQVQDLIATRMGLDGATMNRFGNAAG-----QAYANG
Mvan_4360|M.vanbaalenii_PYR-1 KLFSDAVGDGMATIQLRDQFQARMGLDDSAMAEFGDAAG-----RAYANN
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 TSMTDFNVKPEQAARLMSQMVTAVGSAKTSFQDFAGALHSVEPVAAAAHL
MLBr_00048|M.leprae_Br4923 ------------------------DWSEQLPPN-----------------
MMAR_5451|M.marinum_M PAPPELPPAPPEPPPARPEAPPQAPTAEAEPPDEA----------IPVSG
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 SGVSAVVTKGLDFEKTMNTLSGVTGASADVMQRFRDTAKALG---NDMTL
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 WGQSLEDNLRSLQFGVQSGLIGPDVNEADAQKFIERIQATSGVLEEDPQQ
Mvan_4360|M.vanbaalenii_PYR-1 FGLSLEDTLSTSQAALRTKLVDPDATAAEVQAVIEQLEGMEAVTEATATE
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 KLEDVWGTLAQLTQSGTSPEQATENMRNAINAFTGQSQPARDAMAQFGIN
MLBr_00048|M.leprae_Br4923 PPAASKSPLPPMPIG---------------------------SSVQPP--
MMAR_5451|M.marinum_M PPPGGKSPLPPMPIGGPPPASPEPPAAPPEPTAPAEPPQPPEAAAQPPQA
MUL_3507|M.ulcerans_Agy99 -------------------------------------------MSFVSVT
MAB_0233|M.abscessus_ATCC_1997 SNTSAADAAQAMTELAKAGFSVDESIAGAKGTLQLAAAAQVDAGKAAEIQ
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 IARGVRNFVKTGLVSDYEQAFDLIVASTQKGLNISNDLLDTFEEYGTKFR
Mvan_4360|M.vanbaalenii_PYR-1 LSRSMATLMRTGLADSMSEASDIITAGFQSGLDVSGDWLDTINEYSTQFR
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 ADEVSQKLSERGLAGTMQYLFDTVQSKLLPGMKLNQGELFKSSQAAADLD
MLBr_00048|M.leprae_Br4923 -----------PASSESPRAPMPVSAPPRSPAAS----------------
MMAR_5451|M.marinum_M VEEQAHATAEPPAAPNPPRPPMPIGGPPPTPPAAPEPQQDIAEEPAPAAA
MUL_3507|M.ulcerans_Agy99 QEALAAAASDVGVIGSSLQAANMSVAAP----------------------
MAB_0233|M.abscessus_ATCC_1997 ANALLAFGLKADYASKAADVLSNAANASSAEITDVAQALQSGGAVANQFG
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 DLGINGQEALGLINQLWEGGAR------------------------NVDV
Mvan_4360|M.vanbaalenii_PYR-1 KFGLDAGEFMTLLSQGLEGGAR------------------------DTDK
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 EMITQMSPHAAQLATALKNNEITVKDYTKAARDSVAEDRAKLMEFAQLND
MLBr_00048|M.leprae_Br4923 ------------------------------------------------LM
MMAR_5451|M.marinum_M EAPAAPPKSP------------------------------------LPPM
MUL_3507|M.ulcerans_Agy99 ----------------------------------------------TAGV
MAB_0233|M.abscessus_ATCC_1997 LKLEDTAAAIGLLANNG----------------------------IKGSD
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 AADALKEFAITVVDNSDTTKTALTALGFDAEELGRKFAEGGPTARAAFGA
Mvan_4360|M.vanbaalenii_PYR-1 VADSLKEFSIRAVDGSQSTAEAFAALGFSADEMGRMFAQGGDSAKVALDA
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 KVDGYSKALRTGRDTIETLGKAMRDMTGTVAGQSVALQVSGDHAQETNDR
MLBr_00048|M.leprae_Br4923 PISEPPQWPP--AEAPEHQFAKAEPPSVPIPINEPS------PAKPATPM
MMAR_5451|M.marinum_M PVSGPPPEPPELPPAPPEPTASAEPPQPPQSVEEQAHATAEPPAAPKPTR
MUL_3507|M.ulcerans_Agy99 LAAGADEVSVAMAALFSGHGQAYQTLSAQANAFHAQFLQALTNAGGAYAA
MAB_0233|M.abscessus_ATCC_1997 AGTLLKSALLALTDTSNPAQGAIEELGLTVYDAQGRFVGLEKLFGDLQAA
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 VLDALASVKDPMEQERIGLDLFKTKWEDVGDAIKNLDLPSAANELGNVAG
Mvan_4360|M.vanbaalenii_PYR-1 TFDAIKRIDDPMQQSLIWQQLFGTQFEDMGDAINRFDLDPVKNQFADIEG
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 IKAIATTYTEADGTVKGFHESQDTLNAKMRDAHAAFGAAEAEIGSAFVPV
MLBr_00048|M.leprae_Br4923 PMTPIDGSQRTP-------------VTSPEPSLAEFEAQPPATPKPSL--
MMAR_5451|M.marinum_M PPMPIGGPPPTPEPQQGAPQPHQDIAEEPNPAAAEAPAAPPKSPRPPMP-
MUL_3507|M.ulcerans_Agy99 AEVANLSPLQGVEQGVLGVVNAPAQALLGRPLIGDGAAGTAASPNGGAGG
MAB_0233|M.abscessus_ATCC_1997 SQRMTPEMYQAATTTLFGSDAARLAGIAAKDGAAGYDQMRDAMEKQGSAA
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 KTDEATG---------ALQRHADGWDTLGRNIDETFRKFKEWLADSAIGT
Mvan_4360|M.vanbaalenii_PYR-1 VAARSTQT--------ATDNFSSKWGTATRTVGQYFSDLKTDIAAWFSGL
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 MTEVAKDAKWVGDELAKHPGIAHGVITALEGLGGAWLTFKAIDIVGTILR
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------VNGPAPTRPEPPLPPGPPRRRAQP
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 KLAAAQNQ-----------GLPGVIERLKNAAETLAITLFEKVQGPLSSI
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 -FFSQTLPGFLNAPFEQPPPPPPPAPGQSLGDSGIYGPPVQGPGLNGDGV
Mvan_4360|M.vanbaalenii_PYR-1 PIVSDVLPEMLTTLFGDQPRLQAPGAIQGAVPGTPLNPLDIAAGGTGGWW
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 PIASGLGTIIAQEEGAEVATSRLSTALSGLKAAGILGIGAQLGGQWAQDH
MLBr_00048|M.leprae_Br4923 ---------LPRPMS-SPPEAPRPS-------------------------
MMAR_5451|M.marinum_M PTAPPNQPGQPKPISGHPPPPPRPAAFAPPARGATPNRHESAEPPPPRRV
MUL_3507|M.ulcerans_Agy99 ---------LLYGNGGAGYSYTSGATAEAGGNGGAAGLIGNGGAGGSGWA
MAB_0233|M.abscessus_ATCC_1997 GDGLTGFTNKMQDAFENPAVSQAAGAIGAALSGIGAAFGRILSAVGPALV
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 QVPSDSALPPFLTPGLTGPGLVDPRINAPIPAQPTIPLGP----------
Mvan_4360|M.vanbaalenii_PYR-1 GTSNVPQAETGVPGVVLPPDAASTPLGELLLPSQQGPTPP----------
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 TDPNSFLHSASVVGTDTATGAALGAAAGSIIPGVGTAIGAGVGAAGGFAV
MLBr_00048|M.leprae_Br4923 -----------------ANQHSRHARRGHHHRDETQ--------------
MMAR_5451|M.marinum_M RIGGPPQPPGPPEAESEAPRHSRHARRTHRYRPEPE--------------
MUL_3507|M.ulcerans_Agy99 GGAGGAGGNGGWLYGNGGAGGLGGAAAG----------------------
MAB_0233|M.abscessus_ATCC_1997 GGLSNAVNLIVRFKDFLIPLVAGLVAYKTVMLAITVATKAWAAVQALLNI
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 ---PPPDSPERGPGMPYDQAQQQVADAGRTDSAKPSFDPSQYSVDAIPVP
Mvan_4360|M.vanbaalenii_PYR-1 ---TGPVAPRPTAPTQGTPVPIVPDGADAGSGDKPVIDPSRYSLDSVPIS
Mb1145|M.bovis_AF2122/97 -----------------------------------MISTTRIDFLWILSV
Rv1115|M.tuberculosis_H37Rv -----------------------------------MISTTRIDFLWILSV
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 GLYNQLTSHAEGGPLHAPGPKGHDSALFWGADGEHVLTHQEVQKMGGHSE
MLBr_00048|M.leprae_Br4923 ---QAN-------PASATEPMIAP--------RARTAELRQ---------
MMAR_5451|M.marinum_M ---TDDLEATAVRPLPTREPMRRNGPAADESSTASFAWLQQSQPTLDRPS
MUL_3507|M.ulcerans_Agy99 --------------------DYTAGGVGGAGGNAGLWGDGGAGGNGSATY
MAB_0233|M.abscessus_ATCC_1997 ALTANPIGLIIAAIAGLVAGIVVLYNRNETFRKIVQTTWAAIKTAISAVW
TH_2084|M.thermoresistible__bu ----------------------------------------MSTVAALAVA
MSMEG_2146|M.smegmatis_MC2_155 GAIPMPAVAGAPGAPMPGAGGGMGYYEVDPQRVYDAETSVLS--------
Mvan_4360|M.vanbaalenii_PYR-1 --IRPDQLPGVASSPS------------MSQQVWDMETQLLS--------
Mb1145|M.bovis_AF2122/97 AFAPMIALATLLTLINQVVG--------TPYIPGGDSPAGT---------
Rv1115|M.tuberculosis_H37Rv AFASMIALATLLTLINQVVG--------TPYIPGGDSPAGT---------
Mflv_3272|M.gilvum_PYR-GCK ----MFALATLLTLVNQVSG--------TPYVVGGDSPSGT---------
MAV_0800|M.avium_104 VYKFRSDLMNGRIVLGRAGGGALGYGGMAPDVAVASSLAGTPYSQG----
MLBr_00048|M.leprae_Br4923 -----APHAAAEPAP---------------TQHLTRPDGLVSH-------
MMAR_5451|M.marinum_M GPMPAAPGAPVESAPGRADGRRARRRAESRTSAASTPSPLVPTRAQPPGP
MUL_3507|M.ulcerans_Agy99 DYDQNFSRLGALEGAGGNGG--------HGGLLFGNGGGGGDAG------
MAB_0233|M.abscessus_ATCC_1997 NWLSTTVFPGLKLAFTAIGT--------AATWLWNNAITPAWNG------
TH_2084|M.thermoresistible__bu SPFAAIAVTELVSSTQPAPQ--------QREFVQASLLTDLP--------
MSMEG_2146|M.smegmatis_MC2_155 -ARNSVESARIRVLELEAEGNATAQQLATARQQVTMAERQYVSAQMRLSE
Mvan_4360|M.vanbaalenii_PYR-1 -QRQSVEEARLRVLELEAGGTATQSEINAARTAQQIAERQYVSQLQKLAE
Mb1145|M.bovis_AF2122/97 ----DCSELASWVSNAATARPVFGDRFNTGNEEAALAARGFQQGT-APNA
Rv1115|M.tuberculosis_H37Rv ----DCSELASWVSNAATARPVFGDRFNTGNEEAALAARGFQQGT-APNA
Mflv_3272|M.gilvum_PYR-GCK ----DCSGLVSWVTNAATGRPVYGDRFHTGNIESALLARGFQYGT-QPGA
MAV_0800|M.avium_104 -ARDDCSGMVGRVILGAMGLPAT-NLPTTKNMGQWLAALGFQPGIGGPGS
MLBr_00048|M.leprae_Br4923 ------RTALHDSTATSAIGVQTGRSTGAKKPSKVVAKRGWRHWVHTVTR
MMAR_5451|M.marinum_M TRAQPPRTAAPAQPATEPLPDAGAPAEQSKKPNKPVPQRGWRRWVYAVTR
MUL_3507|M.ulcerans_Agy99 ----ANNKFVTAQATPNGAAGGYGGNAGLWGNGGAGGDGGFGGTATVIGD
MAB_0233|M.abscessus_ATCC_1997 ---IKAVIGVAWEVVSDIFNNWVRVGQLVGQGAMWLWNNAIQPAWDGIKN
TH_2084|M.thermoresistible__bu -----TELMGALSEGLAQFGINLPPMPSLTGSGASMSPGLTSPGLTSPGL
MSMEG_2146|M.smegmatis_MC2_155 AQQGTWKK-----MENAAKGFSKGMDDIGAALDNDLGISEGLPGLADNLV
Mvan_4360|M.vanbaalenii_PYR-1 AQQGTWQK-----LEDSAASFASGMEDIGAALDSDFGLSEGLPGLAENLT
Mb1145|M.bovis_AF2122/97 LVIGWNGH-------HTAVTLPDGTPVSSGEGGG---VRVGGGGAYQPKF
Rv1115|M.tuberculosis_H37Rv LVIGWNGH-------HTAVTLPDGTPVSSGEGGG---VRVGGGGAYQPKF
Mflv_3272|M.gilvum_PYR-GCK LVVGWNSG-------HTAVTLPDGTPVSSGEGGG---VRVGGGGAYQDQF
MAV_0800|M.avium_104 ISVGWYDHGPNPNDGHAAMTLSNGENAEAGGSHGNFVIGAGAAGAASSQF
MLBr_00048|M.leprae_Br4923 INLGLSPD------ERYELDLRTRVRRPPRGS-----YQIGILGLKGGAG
MMAR_5451|M.marinum_M INFGLSPD------EKYELDLRTRIGRKPRGS-----YQIAILGLKGGAG
MUL_3507|M.ulcerans_Agy99 GGTGGNGGLLSGDGGAGGVGGTGGIQIYSGGGIG----GVGGIGGNGGAG
MAB_0233|M.abscessus_ATCC_1997 AISAAWDFVSPILDKFSAGWDALKSGISSASSAIKDAVTSAFSGLAAVIK
TH_2084|M.thermoresistible__bu TSPGLTSP------GLTSPGLTSPGLTSPGLTNP----GLTSPGLTDPAL
. *
MSMEG_2146|M.smegmatis_MC2_155 RFVASLAAAPLLGPLS----------------------------------
Mvan_4360|M.vanbaalenii_PYR-1 KFIANLAAAPLLGQLS----------------------------------
Mb1145|M.bovis_AF2122/97 THHMYLPMDVDAGEDQ---------------------PP-----------
Rv1115|M.tuberculosis_H37Rv THHMYLPMDVDAGEDQ---------------------PP-----------
Mflv_3272|M.gilvum_PYR-GCK TNHMFLP----APAAV---------------------PP-----------
MAV_0800|M.avium_104 DQHMFLPTLYGEGAATGMPGFAAGMGAGGFGGMGGGIPPGATPGTGPGGQ
MLBr_00048|M.leprae_Br4923 KTTVTVTLGSMFARVR----------------------------------
MMAR_5451|M.marinum_M KTTTTVTLGTTLTHVR----------------------------------
MUL_3507|M.ulcerans_Agy99 GTSGLIGDGGAGGAGG----------------------------------
MAB_0233|M.abscessus_ATCC_1997 APLKLLGTFLASIPSEVFG-------------------------------
TH_2084|M.thermoresistible__bu TTPGLTTPGLTTPGLTTPG-------------------------------
MSMEG_2146|M.smegmatis_MC2_155 ----------AISAANPIQGGHGILG------------------------
Mvan_4360|M.vanbaalenii_PYR-1 ----------AIKQAAGDEG-SGLMG------------------------
Mb1145|M.bovis_AF2122/97 ------------APDEPVTAVDDVEP------------------------
Rv1115|M.tuberculosis_H37Rv ------------APDEPVTAVDDVEP------------------------
Mflv_3272|M.gilvum_PYR-GCK ------------PPD---PFLSPPIN------------------------
MAV_0800|M.avium_104 PGYYTANPQRVAAAEERLRHLDAEIDNAEKRRSELKATAKQSERDRLDEE
MLBr_00048|M.leprae_Br4923 ------------NDRILVVDADTSCG------------------------
MMAR_5451|M.marinum_M ------------GDRILVLDADPGAG------------------------
MUL_3507|M.ulcerans_Agy99 ----------TGGGNAGVGGVGGVGG------------------------
MAB_0233|M.abscessus_ATCC_1997 --------FQIPGADKLNSWGKSLQG------------------------
TH_2084|M.thermoresistible__bu ------------LTTPGLDPAQTTPG------------------------
MSMEG_2146|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4360|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 IRHLKAERTQEQQRLAEAERGTFHAMHGRRGAGGGENPFLPVPLADRFGL
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4360|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 SKGLPGLAEWTVGFLEDLVLGPLETAAWAAIGQAPPGAGGAGGGFGGLGV
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 ----------ILGAQGAFGPQYTQ----------SQYAQQGYGYPAG---
Mvan_4360|M.vanbaalenii_PYR-1 ----------ILASNGAFGPRFMP----------NNNGIGAPGYSPS---
Mb1145|M.bovis_AF2122/97 ---------EMPAPCPTQRPPVTP----------RHNLCNKLRTMPG---
Rv1115|M.tuberculosis_H37Rv ---------EMPAPCPTQRPPVTP----------RHNLCNKLRTMPG---
Mflv_3272|M.gilvum_PYR-GCK ---------QLPPPPP---PGAAP----------VVMMGHETALPPG---
MAV_0800|M.avium_104 PGGLGAARFGFPNPAPLAAPPGAPGADDAAAAGLDTARGNTIGPTPSSGG
MLBr_00048|M.leprae_Br4923 ---------NLADRAGRFSEANIA-----------DLLADKDVKSYN---
MMAR_5451|M.marinum_M ---------NLAERSGRSSPSSIA-----------DLLADPRLSHYN---
MUL_3507|M.ulcerans_Agy99 ----------TGGAARLFGSGGSGG--------IGGTGGHSLINSGG---
MAB_0233|M.abscessus_ATCC_1997 ----------FAAGGLVRGPGSGTSDSILAWLSNGEGVVTAKGMKHG---
TH_2084|M.thermoresistible__bu -----------LTTPGVSTPDLTN-----------PALTSPLGEAPG---
.
MSMEG_2146|M.smegmatis_MC2_155 --------------------------------------------YAAGGY
Mvan_4360|M.vanbaalenii_PYR-1 --------------------------------------------TMGPAE
Mb1145|M.bovis_AF2122/97 ---------------------------------------------ALSAA
Rv1115|M.tuberculosis_H37Rv ---------------------------------------------ALSAA
Mflv_3272|M.gilvum_PYR-GCK ---------------------------------------------APLPP
MAV_0800|M.avium_104 AGAGAGASGGGAPSAPADLNGPLTADQIAKLPPDQQLRLLRNAFAHPAPP
MLBr_00048|M.leprae_Br4923 ---------------------------------------------DIRTH
MMAR_5451|M.marinum_M ---------------------------------------------DVRAH
MUL_3507|M.ulcerans_Agy99 ---------------------------------------------GIGGK
MAB_0233|M.abscessus_ATCC_1997 --------------------------------------------AGIVAA
TH_2084|M.thermoresistible__bu ----------------------------------------------GLTT
MSMEG_2146|M.smegmatis_MC2_155 PGDAALLANVPAGR-YSQTGIADLTQGIADCSSAVEDLVN----------
Mvan_4360|M.vanbaalenii_PYR-1 LQQAMTYGVTGGGAPYGLPAGSGSGAQFPAWVRQLERIFG----------
Mb1145|M.bovis_AF2122/97 LAAAAPVWPAPISGCRGFSTSLLAKRNHPVIVGK----------------
Rv1115|M.tuberculosis_H37Rv LAAAAPVWPAPISGCRGFSTSLLAKRNHPVIVGK----------------
Mflv_3272|M.gilvum_PYR-GCK PPPGAPVPPPPP----GMPVPPPPP-GAPA--------------------
MAV_0800|M.avium_104 APAPAPAAPRPQPDADMLPAEVRAWAQQHGMIGPDGNYSGPALPNLGPKS
MLBr_00048|M.leprae_Br4923 TSVNAVNLEVLPAAEYSTAQHALSGEDWNFAAATVSKYYN----------
MMAR_5451|M.marinum_M TSVNAANLEILPTAEYTSAQRGLSGEDLRSAVDTVSKFYN----------
MUL_3507|M.ulcerans_Agy99 GGGGGAAGLIGDGGAGGAGGNGGDGTGAGGLGGN----------------
MAB_0233|M.abscessus_ATCC_1997 LNSGWVPSPAYLADMMRAPGYAEGLNPGADYLRSLVMRMWPQIKSIGGRR
TH_2084|M.thermoresistible__bu PSVGLDPALTPISNTAGLPAPGEVPITAPLGPDPTLGTYP----------
MSMEG_2146|M.smegmatis_MC2_155 ---------------------------------LLDGRPTGGRSLSTHN-
Mvan_4360|M.vanbaalenii_PYR-1 ---------------------------------VSASTYAGHQERDGLNK
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 VAPPVKMQPDLSRLGGNTKGPQPPGPPSAPPTPWTESTRGQSWLHDPNAP
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 SEDGFGEHSTGNAIDIMIPNYQTPQG-------MALGNAIAAFLANNASA
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 -------ADEWLRERGFLPGAGGPGDFRVGFNASHMQATLPGGTPFNWGS
Mvan_4360|M.vanbaalenii_PYR-1 GIDWSGPVENMQRFADYLATIPGSLEQVIWQNPNTGGKTGIADGQFVGPG
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 SWDTGLNLPKLGNQARQFFDLRQPGYFATGGPSGTDTIPAWLSPHEYVEP
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 LDLNGFIWRRQSYGYGGSFTSGTPMDDRGDDNKNHMNHVHVILGSGRGSG
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 DSAAARRGIGGTGADDPAFTSHYYRPAVAGSASVPTIPAAPSVTVYPSTA
Mvan_4360|M.vanbaalenii_PYR-1 TSQPGYYANDWGGHQDHVHTRQSYSLPVPAAPAVPPVPSYPQYQPSTGVA
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 SEAVDKYGPGFMDAIRQGRIDPTSVRYYAPGGEVTDQPEPPPQQQAPAQQ
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 AAAVGLPTSNISLPSGGSVAARAMGNTGSSGGSSKQAREADDRITDLSNR
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 SASPSTAADIYSPANTNPALNNPATPATTPSSLPPVSGGGGTLPFMGQGG
Mvan_4360|M.vanbaalenii_PYR-1 PAPAPVLPSAPVNAGPLPPLPAPGTVPSGGSAMP-GTGFPQAPAFMAPPG
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 PQNMVKAPGAPGGPAIEPPPGAPKPGDNASIHEPTGPGAVSPGSKQGLSD
MLBr_00048|M.leprae_Br4923 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_0233|M.abscessus_ATCC_1997 LDVTEQELADLESNPKAKETTKQRKRDMVDKLKRDLQQAKDDRASLDLGG
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 PQAAPFALNTPVGG--SAFPAQG--GGGFQGVSGLPMDAIMTATQGLDLL
Mvan_4360|M.vanbaalenii_PYR-1 TPGNPIGQSVIPGQPPGVVPGAG--AGMTGGISGIPLAAASAAASSLDFL
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 T-ATPGADVQQPGTGQGALPGIGFSGGIIGGLEGAATQAAAMGADMGTFG
MLBr_00048|M.leprae_Br4923 ---------------------------------------VMLADCGVGLF
MMAR_5451|M.marinum_M ---------------------------------------LVLADCGAGLF
MUL_3507|M.ulcerans_Agy99 -------------------------------------------GASADWI
MAB_0233|M.abscessus_ATCC_1997 SSGGFGGGNNPYAKIMEGISEILPDFGGLADIGIGGLKESLLPPGFSDPM
TH_2084|M.thermoresistible__bu ----------------------------------------ILGDPSLAMA
MSMEG_2146|M.smegmatis_MC2_155 APG--ASQAAQIGIKLANRAIGYAGQLAGIGVSGLMETFLPSGSP-LGNI
Mvan_4360|M.vanbaalenii_PYR-1 APG--AGAAANLGIQLANRTIGFVGQQVGNLWSGVAETFTLSGSGGAPDF
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 GAGGAVSSAMNIGFQELNRAAAYGAQDVGIGVEGLLEALIPNSDATGADW
MLBr_00048|M.leprae_Br4923 DPVTRGVLSTASGVVIVTSTSVDAARQAAIALDWLRHNG-----------
MMAR_5451|M.marinum_M DPVTLGVLDTASAIVILTNVSIDSARQAAIALDWLRKHG-----------
MUL_3507|M.ulcerans_Agy99 GNGGSGGAGGSGGLGAHAGAGGNGGSLYGNDGSGGAGGTGASGAG-----
MAB_0233|M.abscessus_ATCC_1997 QWGFMQAGSTLLKFFGGLRNVSDGKPLLGEGGALMANITGAAMSGSGSGI
TH_2084|M.thermoresistible__bu PPVATSTGGGGLISELSTAANQLGAGQAIDLLKG----------------
MSMEG_2146|M.smegmatis_MC2_155 GNSWFGKVASGFAGARPALPNTAG-----QQAPPNPNPAQPGQPGQQQPG
Mvan_4360|M.vanbaalenii_PYR-1 MKSLPGRALAGIAGARPSMPNTAGGGGQQPQADPRQQQGQQQGPNSGPMV
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 SKTIPGRLLMGVTGVRPAGQQNTAGQTQQPFASNASSDQYANVGNTQPQA
MLBr_00048|M.leprae_Br4923 YQDLLSRACVVINHVMPKEPNIASKDLVQQFEQQIQPGRVVVLPWDKHIA
MMAR_5451|M.marinum_M YQDLASRACVAINHVAVGETNVSEQQLVRDFEQQLQPGRVVVLPWDRHIA
MUL_3507|M.ulcerans_Agy99 -GNGGGGGAAGMMGDGGAGGDGGDGSAAGGLGGDGGNADWLGNGGGGTGG
MAB_0233|M.abscessus_ATCC_1997 VDAIKTIIPAPFGSMDAAQLQGAPGDINPVIAGAQIPGTGFGDMGSAFSQ
TH_2084|M.thermoresistible__bu ------VVMPAVTSAIKSAAQPPGPDVAPPPAPEVPAPDA----------
MSMEG_2146|M.smegmatis_MC2_155 QPINLEYHNHQATEDRAGADITRHLEVQNAPAGQR---------------
Mvan_4360|M.vanbaalenii_PYR-1 EISGDIYQQPGQEPTSVANEISSQVRAAEFSSGWMNARGI----------
Mb1145|M.bovis_AF2122/97 --------------------------------------------------
Rv1115|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3272|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0800|M.avium_104 PIQIMGPVHVQANDPKQLHETSIRRWPSTTQPARSARRGAHRRHTQGEHV
MLBr_00048|M.leprae_Br4923 AGTEIRLDRLDPLYRRRILELAAALSDDFERAGRH---------------
MMAR_5451|M.marinum_M AGTEIHLDQLGPVYRRRVLELAAALSDDFERAGRR---------------
MUL_3507|M.ulcerans_Agy99 FGLPPATGGFGGRGGRLFGSPGAQGRRALMCLSAACRC------------
MAB_0233|M.abscessus_ATCC_1997 GSAAPNGNGSPVDQSINFNAPVGTGVDQAMQKAQSAQNQQYRRNNGTRTM
TH_2084|M.thermoresistible__bu --------------------------------------------------
MSMEG_2146|M.smegmatis_MC2_155 ----------------
Mvan_4360|M.vanbaalenii_PYR-1 ----------------
Mb1145|M.bovis_AF2122/97 ----------------
Rv1115|M.tuberculosis_H37Rv ----------------
Mflv_3272|M.gilvum_PYR-GCK ----------------
MAV_0800|M.avium_104 AERHHHPLRCRPARRR
MLBr_00048|M.leprae_Br4923 ----------------
MMAR_5451|M.marinum_M ----------------
MUL_3507|M.ulcerans_Agy99 ----------------
MAB_0233|M.abscessus_ATCC_1997 PS--------------
TH_2084|M.thermoresistible__bu ----------------