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MSIAAGQQPGRPAGPTRRTTAPRKRGDDTRARIIDETVRCIIEEGFAAATAKHVAERAGVTWGVIQYHFG DRNGLLMAVVDDGVARLVESLSSADVSELPLRQRVEVVIDTAWSCYSSPTSMAAFEILHATRGALGDSSR RHLLDMNAAIGQLGRLITTDPANAGVAEVIWATLRGVVLAQMVIGTTVDWSLERRALIDMVTRVLQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4851 | - | - | 100% (206) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_3668 | - | 3e-11 | 29.10% (189) | hypothetical protein MAV_3668 |
| M. avium 104 | MAV_3767 | - | 5e-10 | 28.99% (138) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 4e-09 | 28.89% (135) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0925 | - | 4e-44 | 47.09% (189) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 4e-09 | 28.89% (135) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-05 | 27.84% (97) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2952c | - | 9e-17 | 30.56% (180) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2638 | - | 1e-11 | 29.70% (202) | AcrR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1565 | - | 3e-12 | 42.35% (85) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2354 | - | 7e-13 | 27.57% (214) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_3113 | - | 7e-12 | 29.70% (202) | AcrR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3785 | - | 1e-13 | 28.23% (209) | hypothetical protein Mvan_3785 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4851|M.avium_104 -----------------------------------------------MSI
Mflv_0925|M.gilvum_PYR-GCK -------------------------------------------------M
MMAR_2638|M.marinum_M --------------------------------------------------
MUL_3113|M.ulcerans_Agy99 -------------------------------------------------M
TH_2354|M.thermoresistible__bu -------------------------------------------------M
Mvan_3785|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MSMEG_1565|M.smegmatis_MC2_155 -------------------------------------------------M
MAB_2952c|M.abscessus_ATCC_199 ---------------------------------MYARKNAKVIALGGWSV
MLBr_00815|M.leprae_Br4923 -------------------------------MNNLAKAAQRRTVRPIDRG
MAV_4851|M.avium_104 AAGQQPGRPAGP-------------TRRTTAPRKRGDDTRARIIDETVRC
Mflv_0925|M.gilvum_PYR-GCK ARSPAARRPPG-------------------GNQERAERTRRTVIDETVRY
MMAR_2638|M.marinum_M --MTDLGVQG-------------------RRTNRRGHATRESMLEAALRS
MUL_3113|M.ulcerans_Agy99 PGMTDLGVQG-------------------RRTNRRGHATRESMLEAALRS
TH_2354|M.thermoresistible__bu PGVSVLKSPGGPPG--------ARPAEVPRRANRRGQATRENMLEAALAA
Mvan_3785|M.vanbaalenii_PYR-1 --MTEAAAPA-------------------RRPNRRGQATRANMLEAALKS
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MSMEG_1565|M.smegmatis_MC2_155 RQTRAARSGPG------------------RPAGTDSVDTRQRVIDAACRC
MAB_2952c|M.abscessus_ATCC_199 VVANLEGRASR------------------RTQAQRSAEMRTRLLDATVEC
MLBr_00815|M.leprae_Br4923 RLSDDIATPNQ------------------RSNRLSRDKRRGQLLIVASDV
* :: :
MAV_4851|M.avium_104 IIEEGFAAATAKHVAERAGVTWGVIQYHFGDRNGLLMAVVDDGVARLVES
Mflv_0925|M.gilvum_PYR-GCK ILDEGFAAPSVRRITERAGLTWGVVQYHFGDLGGLLMAVVDQGIAELTGA
MMAR_2638|M.marinum_M LASGDPGAASANRIAKECGATWGAVKYQFGDIDGFWAAVLHRTAERRGEL
MUL_3113|M.ulcerans_Agy99 LASGDPGAASANRIAKECGATWGAVKYQFGDIDGFWAAVLHRTAERRGEL
TH_2354|M.thermoresistible__bu LATGDPGAVSANRIAKQIGVTWGAVKYQFGDIDGLWAAVLRRTAERRAGV
Mvan_3785|M.vanbaalenii_PYR-1 LASGDPGSVSANRIAKDIGATWGAVQYQFGDADGFWAAVLHRTAERRADV
Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
MSMEG_1565|M.smegmatis_MC2_155 FAQFGYGPATNNQIAEMAGVTAGSVYYHFGTKNKLFEAVCDDVYGKILTR
MAB_2952c|M.abscessus_ATCC_199 LVAHGYAGTTTPRIAEMAGVTRGAQAYHFQSKEDLVVAAIEHLAQQRTQA
MLBr_00815|M.leprae_Br4923 FVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVSS
: . .:: . : * : .
MAV_4851|M.avium_104 LS--SADVSELPLRQRVEVVIDTAWSC---YSSPTSMAAFEILHATRGAL
Mflv_0925|M.gilvum_PYR-GCK LERLRTETANLPAEHRTEVVVDALWQA---FSSPTSMAALEILISTRAAR
MMAR_2638|M.marinum_M PS---NAVSGGPLPERVAAIIDTLYEG---LTS-THSRAIETLRRALPNN
MUL_3113|M.ulcerans_Agy99 PS---NAVSGGPLPERVAAIIDTLYEG---LTS-THSRAIETLRRALPNN
TH_2354|M.thermoresistible__bu IG---RHDAGAPLRERVAGIIDMLYDG---LTA-SDSRAIENLRAALPRD
Mvan_3785|M.vanbaalenii_PYR-1 FA---SVDPDASLRDRVASIIDTLYDG---LAE-PDSRAIENLRAALPRD
Mb0149|M.bovis_AF2122/97 GI--ERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPE
Rv0144|M.tuberculosis_H37Rv GI--ERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPE
MSMEG_1565|M.smegmatis_MC2_155 VM--LAVSGSHSVVGLLRAVLTESMRINHESPELAGFVATAPIDARRHRE
MAB_2952c|M.abscessus_ATCC_199 AIR--EIARLQGNPDPVSAVLDFMWEIH------QGPIFVATMELWIASR
MLBr_00815|M.leprae_Br4923 VQ--QALRTTTNNRQRLHAAVQAFFDF--IEHDGQGYRLIFENDNITEPR
:
MAV_4851|M.avium_104 GDSSRRHLLDMNAAIGQLGR---------LITTD---PANAGVAEVIWAT
Mflv_0925|M.gilvum_PYR-GCK DSDVNAQLVDTMRQFTELGR---------HLGEDLDAPQATEIGNLIWAT
MMAR_2638|M.marinum_M RDELERNYPRTAAELSSWQRSWALACQKAFAGLEVDPNRVREVAAFIPGA
MUL_3113|M.ulcerans_Agy99 RDELERNYPRTAAELSSWQRSWALACQKAFAGLEVDPNRVREVAAFIPGA
TH_2354|M.thermoresistible__bu RAELERLYPRTAAELSSWGEGWLQTCQQAFADLDVDPERVAEVASFIPGA
Mvan_3785|M.vanbaalenii_PYR-1 PAELERLYPQTAAELFSWGQSWLQICHNAFAGLGVDPDRVREVATLIPGA
Mb0149|M.bovis_AF2122/97 LSRTENDAVRATREFLVWAVN-----DAIERGELAADVDVSSLAETLLVV
Rv0144|M.tuberculosis_H37Rv LSRTENDAVRATREFLVWAVN-----DAIERGELAADVDVSSLAETLLVV
MSMEG_1565|M.smegmatis_MC2_155 LAESFATQGARMADALTDAVR-----SGQDAGDIAADLDPVRVARLISAV
MAB_2952c|M.abscessus_ATCC_199 TDKVLAQQIQRMEPFVNSALA------AAIVQLLPEHPAPAELAKIVYTA
MLBr_00815|M.leprae_Br4923 VAAQVRVATESCIDAVFALIS---------ADSRLDPHRARMVAVGLVGI
:. :
MAV_4851|M.avium_104 LRGVVLAQMVIGTTVDWSLERRALIDMVTRVLQ----------
Mflv_0925|M.gilvum_PYR-GCK LRGIVLAQMVSPQPLDTSRDRRTLVDVLNTYMRAKGR------
MMAR_2638|M.marinum_M MRGITSEKQLG-TYSDLDEARRGLTNAIVAYLENSGAR-----
MUL_3113|M.ulcerans_Agy99 MRGITSEKQLG-TYSDLDEARRGLTNAIVAYLENSGVR-----
TH_2354|M.thermoresistible__bu MRGITSERQLG-TYIDLELARRGLTNAIVSYLEDRGPGEKSNQ
Mvan_3785|M.vanbaalenii_PYR-1 MRGLVSERQLG-SYADLDVARRGLTNALVAYLQAAD-------
Mb0149|M.bovis_AF2122/97 LCGVGFYIGFVGSYQRMATITDSFQQLLAGTLWRPPT------
Rv0144|M.tuberculosis_H37Rv LCGVGFYIGFVGSYQRMATITDSFQQLLAGTLWRPPT------
MSMEG_1565|M.smegmatis_MC2_155 VDGFAH-AAVSADPDEMDNMNELFQSLLLDTT-----------
MAB_2952c|M.abscessus_ATCC_199 MDTLRGILIASFVDGDVERARRRWARASAHLRAVAVAAFPSLG
MLBr_00815|M.leprae_Br4923 SVDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL---