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VPKLSDQTRARRRQHILTSAWTCFSRGGFHATSMDDVIAATGMSSSAVYRYFRSKDELIAATVDEGLAKV RGIFLALLDRDPCPTPAETLSLVVAELDSRTRNPQYDMTRIALQTWAEAVRDPFLRKRARSLYRETLRHI TELADRWRDNGHLPPEANTHAAAATLFSVMHGLIVMHHVVDDVGADALRDGLVLLGAAAAPHAVPTTPLP EAHP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0488 | - | - | 100% (215) | putative transcriptional regulator |
| M. avium 104 | MAV_1611 | - | 2e-11 | 34.00% (150) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5275 | - | 1e-08 | 30.68% (176) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 3e-08 | 32.29% (96) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1640 | - | 7e-10 | 31.40% (86) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 3e-08 | 32.29% (96) | transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 6e-07 | 34.25% (73) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1881c | - | 3e-09 | 24.73% (182) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3142 | - | 1e-07 | 26.03% (146) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0363 | - | 6e-08 | 30.57% (157) | TetR-family protein regulatory protein |
| M. thermoresistible (build 8) | TH_4573 | - | 3e-09 | 34.29% (105) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1163 | - | 2e-07 | 34.21% (76) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0126 | - | 6e-08 | 27.86% (140) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02568|M.leprae_Br4923 ----MAGGAKRIPRAVREQ---------QMLDAAVQMFSVNGYHKTSMDA
MUL_1163|M.ulcerans_Agy99 ----MAGGTKRLPRAIREQ---------QMLDAAVQMFSANGYHETSMDT
MSMEG_0363|M.smegmatis_MC2_155 --MGMAGGTKRLPRAVREQ---------QMLDAAVQMFSVNGYHETSMDA
Mb1561|M.bovis_AF2122/97 ----MSRASARRRRAVSDEDKS--QRRDEILAAAKIVFAHKGFHATTVAD
Rv1534|M.tuberculosis_H37Rv ----MSRASARRRRAVSDEDKS--QRRDEILAAAKIVFAHKGFHATTVAD
MAV_0488|M.avium_104 ----MVPKLSDQTRARRRQ---------HILTSAWTCFSRGGFHATSMDD
TH_4573|M.thermoresistible__bu ------MATQRATADVEEQHES--DRRDQILEAANACFAQLGIHRTSVQD
MAB_1881c|M.abscessus_ATCC_199 MLSGMVGKSSPPSAAKLPATAHGRRTRAAIIDAAAQMMYQKGVAATSLDD
Mflv_1640|M.gilvum_PYR-GCK ----MPQPVRQQARTSVRKQ--------QLSQAAARLFTDRGYHNVSMDD
Mvan_0126|M.vanbaalenii_PYR-1 ----MSESTTNGMSRREE-----------LLAVATKLFAARGYHGTRMDD
MMAR_3142|M.marinum_M MFDVRSRNTRWGGRTGAERRAE---RRQQLIEAATEIWSESGWAAVTMRG
: * * . :
MLBr_02568|M.leprae_Br4923 IAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFT-----
MUL_1163|M.ulcerans_Agy99 IAAAAQISKPMLYLYYGSKEDLFGACLNREMSRFIDAVRADIDLS-----
MSMEG_0363|M.smegmatis_MC2_155 IAAAAEISKPMLYLYYGSKEELFGACLDRELRRFVDTVRGQIDFS-----
Mb1561|M.bovis_AF2122/97 IAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELARVGGSTE
Rv1534|M.tuberculosis_H37Rv IAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELARVGGSTE
MAV_0488|M.avium_104 VIAATGMSSSAVYRYFRSKDELIAATVDEGLAKVRGIFLALLDRD---PC
TH_4573|M.thermoresistible__bu VARAANVSRGTVYRYFEDRTILIEAAIEYGAQKFYQEIAAAMAKK-----
MAB_1881c|M.abscessus_ATCC_199 ILAASSTGKSQLYHYFKDRSELVKAVVERQTELVLAAQPTLTQID-----
Mflv_1640|M.gilvum_PYR-GCK IASAVGLTGPALYRHFRKKHDILMQVISEQLGAVEAVAARAVDAG---PT
Mvan_0126|M.vanbaalenii_PYR-1 VADAVGLNKATVYHYYASKSLILYDIYKGAADFTVDALHDDPTATAR---
MMAR_3142|M.marinum_M VCARTGLNDRYFYEDFKTREDLLVAAWDGVRNDMLGEVSALFDERVD---
: .* : : :.
MLBr_02568|M.leprae_Br4923 QSPKDLLRNTIVSFLRYID-------------------------------
MUL_1163|M.ulcerans_Agy99 QSPKDLLRNAIVSFLRYID-------------------------------
MSMEG_0363|M.smegmatis_MC2_155 QSPKELLRTAVLAFLTYID-------------------------------
Mb1561|M.bovis_AF2122/97 APLRALLQAAVQATFEFFE-------------------------------
Rv1534|M.tuberculosis_H37Rv APLRALLQAAVQATFEFFE-------------------------------
MAV_0488|M.avium_104 PTPAETLSLVVAELDSRTR-------------------------------
TH_4573|M.thermoresistible__bu STLAEQLG-AMAETHAKIL-------------------------------
MAB_1881c|M.abscessus_ATCC_199 --SMDGVEQWAQAILANHD-------------------------------
Mflv_1640|M.gilvum_PYR-GCK DERAEVFLAALADLLLEREQVLLWKRERRQLAEEAQRQCRLKLSDVLRLS
Mvan_0126|M.vanbaalenii_PYR-1 ETIYHFTRRLLVGIANDIER------------------------------
MMAR_3142|M.marinum_M RPPIETITAAIAIVVDRIAR------------------------------
MLBr_02568|M.leprae_Br4923 ---------------ANRASWIVMYIQAMSL-PAFAQTVREARDQITELV
MUL_1163|M.ulcerans_Agy99 ---------------QNQASWIVMYTQAVSS-QAFAQTVREGREQIVELV
MSMEG_0363|M.smegmatis_MC2_155 ---------------RNRASWMVLYTQATSS-QAFAHTVREGRERIIDLV
Mb1561|M.bovis_AF2122/97 ---------------TDKATVKLLFRDAYALGGRFEEHLGGIYERFIDDI
Rv1534|M.tuberculosis_H37Rv ---------------TDKATVKLLFRDAYALGGRFEEHLGGIYERFIDDI
MAV_0488|M.avium_104 ---------------NPQYDMTRIALQTWAEAVRDPFLRKRARSLYRETL
TH_4573|M.thermoresistible__bu ---------------LDHRTRNRLMTDDAELMRHMIADADAAVRRTTEFL
MAB_1881c|M.abscessus_ATCC_199 ---------------VPGGPFGCPLGSMAAELKNDPAYQPALAAAFGQWQ
Mflv_1640|M.gilvum_PYR-GCK SQALGLTSGEKPSGQAELRTWAVLGIYSSVAPIRNRVENATAKRLLRAAA
Mvan_0126|M.vanbaalenii_PYR-1 ----------------AAVYFQEGPYITEWFTEEQVEYIREKETQVYEHV
MMAR_3142|M.marinum_M -------------DPGRAHILLAQHVGSSPLQDRRAVALQEATQLVVEAS
MLBr_02568|M.leprae_Br4923 AGLMRVGTRSSRPDHEYEIMAG-----------ALVG--AGEAMATRLTT
MUL_1163|M.ulcerans_Agy99 AGMLRAGTRSPRSDAEIDMMAA-----------ALVG--AGEAVANRLSA
MSMEG_0363|M.smegmatis_MC2_155 ARLLSTGTRNPQPDSDFEMMAV-----------ALVG--AGEAIATRVST
Mb1561|M.bovis_AF2122/97 EAVVVAAQRRGEVVEAPSRMAA-----------YTLAALVGQLAHRRLNT
Rv1534|M.tuberculosis_H37Rv EAVVVAAQRRGEVVEAPSRMAA-----------YTLAALVGQLAHRRLNT
MAV_0488|M.avium_104 RHITELADRWRDNGHLPPEANT-----------HAAAATLFSVMHGLIVM
TH_4573|M.thermoresistible__bu MPYVQQAKERGEVG---SGVDV-----------KAASEWLARIIYSFTTV
MAB_1881c|M.abscessus_ATCC_199 SLLADGLIRMQDRGHLDPHEDP-----------QRLAAAVLATLQGGMLM
Mflv_1640|M.gilvum_PYR-GCK LNILGCELDTGLPRSATPVTHRRQPPGRRERILSTAGRLFHAQSYHAVGI
Mvan_0126|M.vanbaalenii_PYR-1 RDVIDRGIASGEFYDCDSHVLALGYIG------MTLGSYRWLRPHGRRTA
MMAR_3142|M.marinum_M RPHLREDADETALRMDTLVAVG------------GFVEVITAWHSGLLAV
MLBr_02568|M.leprae_Br4923 GD-IAVDEAAELMINLFWHG-----------------------LKGAPAD
MUL_1163|M.ulcerans_Agy99 GD-TDVDEAAEMMIDLLWRG-----------------------LKGAPSD
MSMEG_0363|M.smegmatis_MC2_155 GD-ADVDEAAELMINLFWRG-----------------------LKGTPSD
Mb1561|M.bovis_AF2122/97 DDNVTAAQVADFVVSLVLDG-----------------------LRPRALA
Rv1534|M.tuberculosis_H37Rv DDNVTAAQVADFVVSLVLDG-----------------------LRPRALA
MAV_0488|M.avium_104 HHVVDDVGADALRDGLVLLG-----------------------AAAAPHA
TH_4573|M.thermoresistible__bu NEGLTFDMSKPATVRRYVER-----------------------FAVNGLR
MAB_1881c|M.abscessus_ATCC_199 GRATMDITVLRDSLEMALDS-----------------------IRRALRD
Mflv_1640|M.gilvum_PYR-GCK EEIAAESDTAIATFYQYFNGKGELLHALLNRGAEGLHYVTNHRLASAATA
Mvan_0126|M.vanbaalenii_PYR-1 QEIAVEFSTALLRGLIRDET----------------------VRTLSPLG
MMAR_3142|M.marinum_M TEKEVVAHTSRLAETLAQRY-----------------------VVSG---
MLBr_02568|M.leprae_Br4923 RDFGPSIVAG----------------------------------------
MUL_1163|M.ulcerans_Agy99 REIGSNFAAG----------------------------------------
MSMEG_0363|M.smegmatis_MC2_155 AGT-PPVSAGSSG-------------------------------------
Mb1561|M.bovis_AF2122/97 VGARGGRAART---------------------------------------
Rv1534|M.tuberculosis_H37Rv VGARGGRAART---------------------------------------
MAV_0488|M.avium_104 VPTTPLPEAHP---------------------------------------
TH_4573|M.thermoresistible__bu --------------------------------------------------
MAB_1881c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1640|M.gilvum_PYR-GCK QDALDTVASTLIELALGPHQPILAILAADLVYLPDAARELIRMSEREYTD
Mvan_0126|M.vanbaalenii_PYR-1 VGIDAPVKTRILEEPS----------------------------------
MMAR_3142|M.marinum_M --------------------------------------------------
MLBr_02568|M.leprae_Br4923 --------------------------------------------------
MUL_1163|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0363|M.smegmatis_MC2_155 --------------------------------------------------
Mb1561|M.bovis_AF2122/97 --------------------------------------------------
Rv1534|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0488|M.avium_104 --------------------------------------------------
TH_4573|M.thermoresistible__bu --------------------------------------------------
MAB_1881c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1640|M.gilvum_PYR-GCK EWVAALVGVCPELTPPHARLLARAAIGLITDITQIQKMRMRPGIATELHQ
Mvan_0126|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3142|M.marinum_M --------------------------------------------------
MLBr_02568|M.leprae_Br4923 --------
MUL_1163|M.ulcerans_Agy99 --------
MSMEG_0363|M.smegmatis_MC2_155 --------
Mb1561|M.bovis_AF2122/97 --------
Rv1534|M.tuberculosis_H37Rv --------
MAV_0488|M.avium_104 --------
TH_4573|M.thermoresistible__bu --------
MAB_1881c|M.abscessus_ATCC_199 --------
Mflv_1640|M.gilvum_PYR-GCK LVNAVLAA
Mvan_0126|M.vanbaalenii_PYR-1 --------
MMAR_3142|M.marinum_M --------