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MLLTVLRFNFASPHGDPRTQSRLMSAALELAQWGESHGITSVSVDEHHATGHGWSCNPIMAAAMFLARTS TLIASVDCALGPLWNPVRLAEDIALVDNMSRGRLHTTVGLGYRPVEYDALGADFGRRGALMDSLLERMLA VWSGGGAPAGICTGTWTRPHPPLYVGGGARATARRAARFRLPLSLADHLPEIADYYRELCAEIDLAPVVL MPGPLNRGMIYLHEDPERAWAELGDHILWEAVTYGGWSTDQRSLMHLPGVQTLDEVRASGRYRFLTPDQL IAEVRDAPDFGPIVLHPLVGGMPVEEAWQSVQLLTDKVLPALKG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0338 | - | - | 100% (324) | hypothetical protein MAV_0338 |
| M. avium 104 | MAV_2133 | - | 8e-40 | 32.82% (326) | hypothetical protein MAV_2133 |
| M. avium 104 | MAV_2659 | - | 7e-18 | 34.18% (196) | hypothetical protein MAV_2659 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 4e-11 | 31.97% (122) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_4097 | - | 7e-13 | 28.02% (207) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 4e-11 | 31.97% (122) | hypothetical protein Rv3079c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0366 | - | 9e-15 | 32.04% (181) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_0236 | - | 4e-59 | 37.96% (324) | hypothetical protein MMAR_0236 |
| M. smegmatis MC2 155 | MSMEG_5626 | - | 3e-13 | 39.25% (107) | luciferase |
| M. thermoresistible (build 8) | TH_3375 | - | 2e-25 | 28.92% (332) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4877 | - | 4e-59 | 37.96% (324) | hypothetical protein MUL_4877 |
| M. vanbaalenii PYR-1 | Mvan_2248 | - | 4e-13 | 30.22% (182) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 --MQFGVLTFVT---------DEGIGPAELGAALEHRGFESLFLAEHTHI
Rv3079c|M.tuberculosis_H37Rv --MQFGVLTFVT---------DEGIGPAELGAALEHRGFESLFLAEHTHI
Mflv_4097|M.gilvum_PYR-GCK --MQFAITHPMHSHPY-NPELVTGAGIARVAVAAEKAGFGGFGFTDH---
Mvan_2248|M.vanbaalenii_PYR-1 --MQFAITHPMHSHPY-NPELVTGTGIAQVAQAAEKAGFGGFGFTDH---
MMAR_0236|M.marinum_M --MSLLTALRLN--------MTNIADPAADHAQRYRAALDMAEYADHHGF
MUL_4877|M.ulcerans_Agy99 --MSLLTALRLN--------MTNIADPAADHAQRYRAALDMAEYADHHGF
MAV_0338|M.avium_104 ---MLLTVLRFN--------FASPHGDPRTQSRLMSAALELAQWGESHGI
TH_3375|M.thermoresistible__bu --VGLGALTAQT-----------RSGTAAESTEALTMLLDTCVLAEDEGL
MAB_0366|M.abscessus_ATCC_1997 --MKIGVVAPVELG-----VTAEPDKILEFARAAERLGFSEISVVEHAVV
MSMEG_5626|M.smegmatis_MC2_155 MKVNLGTGAQNSRDWERVLAEDWSRPPATPDHQCVQAALALGDLAEPLGF
: : :
Mb3106c|M.bovis_AF2122/97 PVNTQSPYPGGGPIPEKY---YRTLDPFVALAAAAATTQSLVLGTGIALI
Rv3079c|M.tuberculosis_H37Rv PVNTQSPYPGGGPIPEKY---YRTLDPFVALAAAAATTQSLVLGTGIALI
Mflv_4097|M.gilvum_PYR-GCK PAPTQRWLEAGG---------HDALDPFVAMGFAAAHTTTLRLIPNIVVL
Mvan_2248|M.vanbaalenii_PYR-1 PAPTQRWLEAGG---------HDALDPFVAMGFAAAHTSTLRLIPNIVVL
MMAR_0236|M.marinum_M TAVSAEEHHLAATG--------WLPSPLILAAAVAGRTRNVRISINALIV
MUL_4877|M.ulcerans_Agy99 TAVSAEEHHLAATG--------WLPSPLILAAAVAGRTRNVRISINALIV
MAV_0338|M.avium_104 TSVSVDEHHATGHG--------WSCNPIMAAAMFLARTSTLIASVDCALG
TH_3375|M.thermoresistible__bu DSAWVAEHHFAADG--------FLSSPMTVLAALSQRTSRIRLSTNVMIG
MAB_0366|M.abscessus_ATCC_1997 IGDTQSTYPYSPTGQSHLPDDIDIPDPLELLSFVAAATTTLGLSTGVLVL
MSMEG_5626|M.smegmatis_MC2_155 DGIWFPEHHGTPYG--------MTPNPIQALTYFAGRTERVSLGTFVAVV
.*: * : :
Mb3106c|M.bovis_AF2122/97 PERDPIVTAKEVASLDLVSQGRFR-FGVGVGWLREEVANHGVDPAVRGRV
Rv3079c|M.tuberculosis_H37Rv PERDPIVTAKEVASLDLVSQGRFR-FGVGVGWLREEVANHGVDPAVRGRV
Mflv_4097|M.gilvum_PYR-GCK PYRNPFVVAKAGATLDLISDGRFT-LAVGVGYLKREFAALGVEFDERAAV
Mvan_2248|M.vanbaalenii_PYR-1 PYRNPFVVAKAGATLDLISEGRFT-LAVGVGYLKREFTALGVDFDERAEL
MMAR_0236|M.marinum_M PLYDPVRLAEDIAVLDNLSQGRFS-FVAGMGYRPQEYHAAGKDWSRRGAL
MUL_4877|M.ulcerans_Agy99 PLYDPVRPAEDIAVLDNLSQGRFS-FVAGMGYRPQEYHAAGKDWSRRGAL
MAV_0338|M.avium_104 PLWNPVRLAEDIALVDNMSRGRLH-TTVGLGYRPVEYDALGADFGRRGAL
TH_3375|M.thermoresistible__bu PLYDPIRLAEDAAVVDQLSRGRLM-LGLGLGYRDVEFAGLGRRRQERGRR
MAB_0366|M.abscessus_ATCC_1997 PDHHPVVLAKRLATLDRLSRGRLR-ICAGVGWMREEIEACGGDFDRRGRA
MSMEG_5626|M.smegmatis_MC2_155 PWWNPIRLATQIAYLDIVSNGRYTTIGLGRGVSKGEFAAVGVPREESRQR
* .*. * * :* :* ** * * * *
Mb3106c|M.bovis_AF2122/97 IDERLRAIIEIWTQEQ-AEFHGTYVDFDPIYCWPKPVT------------
Rv3079c|M.tuberculosis_H37Rv IDERLRAIIEIWTQEQ-AEFHGTYVDFDPIYCWPKPVT------------
Mflv_4097|M.gilvum_PYR-GCK FEEALDVITQIWTTDD-LSYDGRNFSAKGITAHPKPLT------------
Mvan_2248|M.vanbaalenii_PYR-1 FEESLQVIRDAWTTDD-ITFEGKHFSAKGITAHPRPVS------------
MMAR_0236|M.marinum_M MDHCLSVLLQAWGDDP-FEYDGRLINVT-----PKPRT------------
MUL_4877|M.ulcerans_Agy99 MDHCLSVLLQAWGDDP-FEYDGRLINVT-----PKPRT------------
MAV_0338|M.avium_104 MDSLLERMLAVWSGG------GAPAGIC-----TGTWT------------
TH_3375|M.thermoresistible__bu LDDLINVLRQAWSGKP-VEHHGLGTYKTP-PVTPLPFQ------------
MAB_0366|M.abscessus_ATCC_1997 ADEAIAVMRALWSTDGPTSHDGEFYSFRNAYSYPKPVR------------
MSMEG_5626|M.smegmatis_MC2_155 FNETLDILKLAFSGER-FSYEGEIFSFPEMSLRPEPISTDLYDRIYSSSS
: : : : * . .
Mb3106c|M.bovis_AF2122/97 ----------KPYPPLYVGG-GPANFPRIARLNAGWIAISP---------
Rv3079c|M.tuberculosis_H37Rv ----------KPYPPLYVGG-GPANFPRIARLNAGWIAISP---------
Mflv_4097|M.gilvum_PYR-GCK ----------TPHPPIWVGGNTSAARARVAKYAQGWCPFRAPAMLAQTAR
Mvan_2248|M.vanbaalenii_PYR-1 ----------TPHPPIWVGGNTSAARARVARYAQGWCPFRAPAVLAQTAR
MMAR_0236|M.marinum_M ----------HPHPILFVGGMSVAAARRAAHFGLPFSPPMAMPELEAVYH
MUL_4877|M.ulcerans_Agy99 ----------HPHPILFVGGMSVAAARRAARFGLPFSPPMAMPELEAVYH
MAV_0338|M.avium_104 ----------RPHPPLYVGGGARATARRAARFRLPLSLADHLPEIADYYR
TH_3375|M.thermoresistible__bu ----------QDGPPVLVGAFAEAGLRRAVRLGNGWLAPELRHWRGLEKR
MAB_0366|M.abscessus_ATCC_1997 ----------PQGVPLYIGGHSKAAARRAGRLGSGFQPLGLVG-------
MSMEG_5626|M.smegmatis_MC2_155 TAESLEILSRRGMVPLFVGNKPITDAGEEVKKVNTFRAEEGLPPCQPKNV
: :* : . :
Mb3106c|M.bovis_AF2122/97 --------------------SPQRLSGPLQRLRAMAGG------------
Rv3079c|M.tuberculosis_H37Rv --------------------SPQRLSGPLQRLRAMAGG------------
Mflv_4097|M.gilvum_PYR-GCK TAALE---------------TTEHLAKGIDDLRRRLEDAGR---------
Mvan_2248|M.vanbaalenii_PYR-1 TAALE---------------TVEHLKAGIDDLRRRLEGTGR---------
MMAR_0236|M.marinum_M QELARRNKRGFVYHP-ENGSTVTLLHADPDEAWSRFGGFIMNEATEYSGW
MUL_4877|M.ulcerans_Agy99 QELARRNKRGFVYHP-ENGSTVTLLHADPDEAWSRFGGFIMNEATEYSGW
MAV_0338|M.avium_104 ELCAEIDLAPVVLMPGPLNRGMIYLHEDPERAWAELGDHILWEAVTYGGW
TH_3375|M.thermoresistible__bu VAALGLDSR----TDPFHVAVTVNAFVAARDAWETVRPGVAHVAGQYRSW
MAB_0366|M.abscessus_ATCC_1997 ----------------------DDLTAAVGVMRAAAVDAGR---------
MSMEG_5626|M.smegmatis_MC2_155 MFMYCTNSQD---EIEQTEEWIWTANRDVNVHYGFADASNFRGVKGYEAY
Mb3106c|M.bovis_AF2122/97 -----------DVPVTVCQWGEA---AAKDLEG---YRHLG---------
Rv3079c|M.tuberculosis_H37Rv -----------DVPVTVCQWGEA---AAKDLEG---YRHLG---------
Mflv_4097|M.gilvum_PYR-GCK ------DPADVDITFTNDAGGAP---GTDDFNA---DEFLAGAEELERAG
Mvan_2248|M.vanbaalenii_PYR-1 ------DPFDIDITFTNDAGGSP---GAADFNA---DEFLSGAAELERAG
MMAR_0236|M.marinum_M KRADVPRPNEAPAASIAELRGLD---NVQILTP---DQLVGQLQRGRKE-
MUL_4877|M.ulcerans_Agy99 KRADVPRPNEAPAASIAELRSLD---NVQILTP---DQLVGQLQRGRKE-
MAV_0338|M.avium_104 STDQRSLMHLPGVQTLDEVRASG---RYRFLTP---DQLIAEVRDAPDFG
TH_3375|M.thermoresistible__bu LVESGDLPALEGKEFEYEADETG---KPPQFVAGTPEQCVAQLRPWWRIL
MAB_0366|M.abscessus_ATCC_1997 ------DPRGLDLVLGHGLHRVD---QAALDQA----AHAGAGR------
MSMEG_5626|M.smegmatis_MC2_155 AAREASATAVLASEVGNQKKGGPPGYHASNLLIGSPETVYEKLKAAQEAC
Mb3106c|M.bovis_AF2122/97 V---------ERVLLELPTEPRDPTLRYLDKLQAELARLA----------
Rv3079c|M.tuberculosis_H37Rv V---------ERVLLELPTEPRDPTLRYLDKLQAELARLA----------
Mflv_4097|M.gilvum_PYR-GCK V---------TWLQVNVPGDSLAHAVEAIEGFGETVIAQR----------
Mvan_2248|M.vanbaalenii_PYR-1 V---------TWIQVTVPGDSLAHTLEAIEEFGGSVIGRP----------
MMAR_0236|M.marinum_M ----------VVMNPLIGGLPVEVGWSSLRLLAEEVLPRVADIPDSATTK
MUL_4877|M.ulcerans_Agy99 ----------VVMNPLIGGLPVEVGWSSLRLLAEEVLPRVADIPDSATTK
MAV_0338|M.avium_104 P---------IVLHPLVGGMPVEEAWQSVQLLTDKVLPALKG--------
TH_3375|M.thermoresistible__bu ARLPEHVQPHLILGMTFPGVSREATFESVRLLAREVVPALNAEE------
MAB_0366|M.abscessus_ATCC_1997 ----------MLLSASRRATTLEAVLEEMAGCATRLELGGPR--------
MSMEG_5626|M.smegmatis_MC2_155 S------FSEVTIVPQFGTMPYEEAMESVKLFAAEVLPAVHDMPAPLHPS
: . : :
Mb3106c|M.bovis_AF2122/97 --------
Rv3079c|M.tuberculosis_H37Rv --------
Mflv_4097|M.gilvum_PYR-GCK --------
Mvan_2248|M.vanbaalenii_PYR-1 --------
MMAR_0236|M.marinum_M P-------
MUL_4877|M.ulcerans_Agy99 P-------
MAV_0338|M.avium_104 --------
TH_3375|M.thermoresistible__bu --------
MAB_0366|M.abscessus_ATCC_1997 --------
MSMEG_5626|M.smegmatis_MC2_155 VLPESVTA