For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VYTLRFDMRDPEWAAPPADLYAAAPEMAAWAEEHGGLAAVLCEHHGSEDGYLPSPFLLASAVAARTQRLA LSLILILPFYEPVRLAEDMAVLDIISNGRASYILALGYRPEEFEHFGVPIKKRGRLCDEKLALLRRLLAG ETVVEDGRRITVTPRPLTPGGPGLMWGGGTIAAARRAGRYGLGMLGNANAPGIQEAYEEACREHGHPPGP TMFPDRNTPSVVFVAEDVDQAWKEIGEHLLHDVRTYAAWNPGDETTAGFSHVNTIDELRETGTSHVIISV PEAISRVKAGQVLNLSPLCGGLPPDIAWPYLKRVGEVVLPEALGH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2133 | - | - | 100% (325) | hypothetical protein MAV_2133 |
| M. avium 104 | MAV_0338 | - | 8e-40 | 32.82% (326) | hypothetical protein MAV_0338 |
| M. avium 104 | MAV_5129 | - | 2e-15 | 34.81% (135) | hypothetical protein MAV_5129 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 2e-11 | 31.47% (143) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_1590 | - | 1e-14 | 31.82% (198) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 2e-11 | 31.47% (143) | hypothetical protein Rv3079c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0366 | - | 2e-18 | 39.86% (148) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_3375 | - | 3e-54 | 37.93% (319) | hypothetical protein MMAR_3375 |
| M. smegmatis MC2 155 | MSMEG_4820 | - | 1e-16 | 27.78% (234) | hypothetical protein MSMEG_4820 |
| M. thermoresistible (build 8) | TH_3375 | - | 6e-25 | 34.51% (226) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4877 | - | 6e-49 | 36.08% (316) | hypothetical protein MUL_4877 |
| M. vanbaalenii PYR-1 | Mvan_5167 | - | 1e-15 | 31.79% (195) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1590|M.gilvum_PYR-GCK MQLVFPLPHMLRLPAMSQPWEGSVTGADQTRMAKCADAWGYDMIAVPEHF
Mvan_5167|M.vanbaalenii_PYR-1 MRLVFALPHMLRLPAMSQPWEASVTGADQTRMARCADQWGYDMIAVPEHF
Mb3106c|M.bovis_AF2122/97 --MQFGVLTFVTDEGIGP---AELGAALEHRGFESLFLAEHTHIPVNTQS
Rv3079c|M.tuberculosis_H37Rv --MQFGVLTFVTDEGIGP---AELGAALEHRGFESLFLAEHTHIPVNTQS
MAV_2133|M.avium_104 ----------MYTLRFDMR-DPEWAAPPADLYAAAPEMAAWAEEHG--GL
MMAR_3375|M.marinum_M ------MRTIETTVSFDMR-APEWGAPTAELYRAAIEMAAFADGIG--VD
MUL_4877|M.ulcerans_Agy99 -------MSLLTALRLNMTNIADPAADHAQRYRAALDMAEYADHHG--FT
MAB_0366|M.abscessus_ATCC_1997 -MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVEHAVVIGDTQS
MSMEG_4820|M.smegmatis_MC2_155 ------MRYSITHPMHSHPYHPDLVSGSGVVAVAAAAEAAGFDGFGFTDH
TH_3375|M.thermoresistible__bu ----------VGLGALTAQTRSGTAAESTEALTMLLDTCVLAEDEGLDSA
Mflv_1590|M.gilvum_PYR-GCK VIP----AEHVELSGPHYLQSTVAQAYLAGATERIRLNSCITVLPLQHPI
Mvan_5167|M.vanbaalenii_PYR-1 VIP----AEHVELSGPHYLQSTVAQAYLAGATERIRLNSCITVLPLQHPV
Mb3106c|M.bovis_AF2122/97 PYPG---GGPIPEKYYRTLDPFVALAAAAATTQSLVLGTGIALIPERDPI
Rv3079c|M.tuberculosis_H37Rv PYPG---GGPIPEKYYRTLDPFVALAAAAATTQSLVLGTGIALIPERDPI
MAV_2133|M.avium_104 AAVL---CEHHGSEDGYLPSPFLLASAVAARTQRLALSL-ILILPFYEPV
MMAR_3375|M.marinum_M NISV---MEHHGSEDGYLPQPFTMAGGMAAVTKHARLLIGAVVLPLHDPV
MUL_4877|M.ulcerans_Agy99 AVSA---EEHHLAATGWLPSPLILAAAVAGRTRNVRISINALIVPLYDPV
MAB_0366|M.abscessus_ATCC_1997 TYPYSPTGQSHLPDDIDIPDPLELLSFVAAATTTLGLSTGVLVLPDHHPV
MSMEG_4820|M.smegmatis_MC2_155 PAPS---QRWLDAGGHDAVDPFVAMAYAAAQTTTLRLVPNIVVLPYRNPF
TH_3375|M.thermoresistible__bu WVA-----EHHFAADGFLSSPMTVLAALSQRTSRIRLSTNVMIGPLYDPI
.. . : * : : * .*.
Mflv_1590|M.gilvum_PYR-GCK VLAKALATADWMSGGRMMVTFGVGWLKGEFDALGVPFRERGRIADEYLAA
Mvan_5167|M.vanbaalenii_PYR-1 VLAKALATADWMSGGRMMVTFGVGWLQGEFEALGVPFRERGRMADEYLAV
Mb3106c|M.bovis_AF2122/97 VTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRVIDERLRA
Rv3079c|M.tuberculosis_H37Rv VTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRVIDERLRA
MAV_2133|M.avium_104 RLAEDMAVLDIISNGRASYILALGYRPEEFEHFGVPIKKRGRLCDEKLAL
MMAR_3375|M.marinum_M LVAEQIAIADLMSGGRINVTFGAGYVASEFAMFGKSLADRAKLMDSGIET
MUL_4877|M.ulcerans_Agy99 RPAEDIAVLDNLSQGRFSFVAGMGYRPQEYHAAGKDWSRRGALMDHCLSV
MAB_0366|M.abscessus_ATCC_1997 VLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRRGRAADEAIAV
MSMEG_4820|M.smegmatis_MC2_155 VVAKSGATLDLLSGGRFTLAVGVGYLKREFAALGVAFDERTELFDESLEV
TH_3375|M.thermoresistible__bu RLAEDAAVVDQLSRGRLMLGLGLGYRDVEFAGLGRRRQERGRRLDDLINV
*: * * :* ** . *: * * * * :
Mflv_1590|M.gilvum_PYR-GCK IVELWTSD-SPSFDGRYVSFDEIAFEPKPVQRPHLPIWIGGDADAALRRA
Mvan_5167|M.vanbaalenii_PYR-1 IKELWTSD-APSFEGKYVSFREVAFEPKPVQKPHLPIWIGGDADAALRRA
Mb3106c|M.bovis_AF2122/97 IIEIWTQE-QAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGGGP-ANFPRI
Rv3079c|M.tuberculosis_H37Rv IIEIWTQE-QAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGGGP-ANFPRI
MAV_2133|M.avium_104 LRRLLAGE-TVVEDG-----RRITVTPRPLTPGGPGLMWGGGTIAAARRA
MMAR_3375|M.marinum_M IIRALRGE-TFEADG-----RPVCVRPLPIQKPEEIILVGGGVKASARRA
MUL_4877|M.ulcerans_Agy99 LLQAWGDD-PFEYDG-----RLINVTPKPRTHPHPILFVGGMSVAAARRA
MAB_0366|M.abscessus_ATCC_1997 MRALWSTDGPTSHDGEFYSFRNAYSYPKPVRPQGVPLYIGGHSKAAARRA
MSMEG_4820|M.smegmatis_MC2_155 IRGIWTTD-DFTYEGMHFSARGITAHPRPVNPP--PIWIGGNTAAARARV
TH_3375|M.thermoresistible__bu LRQAWSGK-PVEHHG-LGTYKTPPVTPLPFQQDGPPVLVGAFAEAGLRRA
: . .* * * : *. * *
Mflv_1590|M.gilvum_PYR-GCK AKYASGWWSFLTPPDKIAER----VEFIKSQD------------------
Mvan_5167|M.vanbaalenii_PYR-1 AKYASGWWSFLTPPEKLAER----LDFIKSQP------------------
Mb3106c|M.bovis_AF2122/97 ARLNAGWIAISPSPQRLSGP----LQRLRAMA------------------
Rv3079c|M.tuberculosis_H37Rv ARLNAGWIAISPSPQRLSGP----LQRLRAMA------------------
MAV_2133|M.avium_104 GRYGLGMLGNANAPGIQEAY----EEACREHGHPPGPTMFPDRNTPSVVF
MMAR_3375|M.marinum_M ARFGLGFLP--MVPDLVDVY----LEECRKHGREPG-LYFRPMLIPISIH
MUL_4877|M.ulcerans_Agy99 ARFGLPFSPPMAMPELEAVY----HQELARRN--KRGFVYHPENGSTVTL
MAB_0366|M.abscessus_ATCC_1997 GRLGSGFQPLGLVGDDLTAA----VGVMRAAA----------------VD
MSMEG_4820|M.smegmatis_MC2_155 ARHGDGWCPFAAPPGLAQTAGTAAIDSIERLAAG-------------IAD
TH_3375|M.thermoresistible__bu VRLGNGWLAPELRHWRGLEKRVAALGLDSRTDP---------FHVAVTVN
:
Mflv_1590|M.gilvum_PYR-GCK -GYDGRPFDVVHGLGTNRVGEGHVAQKDPHARPGMS-AAEIADKLNWLGE
Mvan_5167|M.vanbaalenii_PYR-1 -DYDGRPFDVVHGLGTNRVGEGHVAQHDPDARPGMS-AAEIVDRLSWLGA
Mb3106c|M.bovis_AF2122/97 -GGDVP---------------------VTVCQWGEA-AAKDLEGYRHLGV
Rv3079c|M.tuberculosis_H37Rv -GGDVP---------------------VTVCQWGEA-AAKDLEGYRHLGV
MAV_2133|M.avium_104 VAEDVDQAWKEIGEHLLHDVRTYAAWNP--GDETTA-GFSHVNTIDELRE
MMAR_3375|M.marinum_M LCEDPERGWAAIERHAIHVITEYAKWAEQEGDASNS-PFKSLTDPAVLRQ
MUL_4877|M.ulcerans_Agy99 LHADPDEAWSRFGGFIMNEATEYSGWKR--ADVPRP-NEAPAASIAELRS
MAB_0366|M.abscessus_ATCC_1997 AGRDPRGLDLVLG-----------------HGLHRV-DQAALDQAAHAGA
MSMEG_4820|M.smegmatis_MC2_155 LRAKLDAAQRDPSTVDIVFTNFDGGNPGDDDFDADA-YLAGVDQLAALGV
TH_3375|M.thermoresistible__bu AFVAARDAWETVRPGVAHVAGQYRSWLVESGDLPALEGKEFEYEADETGK
Mflv_1590|M.gilvum_PYR-GCK QGVTVSAVPIPKVSGVEEYLDYAQ---------WVIEEIRPQVR------
Mvan_5167|M.vanbaalenii_PYR-1 QGVTVSAVPIPKVRGVEEYLDYAQ---------WVIEEIKPQVP------
Mb3106c|M.bovis_AF2122/97 ERVLLELPTEPRDP-TLRYLDKLQ---------AELARLA----------
Rv3079c|M.tuberculosis_H37Rv ERVLLELPTEPRDP-TLRYLDKLQ---------AELARLA----------
MAV_2133|M.avium_104 TG--TSHVIISVPEAISRVKAGQV---------LNLSPLCGGLPPDIAWP
MMAR_3375|M.marinum_M AGLFAAWTPDDLLARVPDMVDRSG---------FAFQPLLGGLSPEEGWK
MUL_4877|M.ulcerans_Agy99 LDNVQILTPDQLVGQLQ--RGRKE---------VVMNPLIGGLPVEVGWS
MAB_0366|M.abscessus_ATCC_1997 GRMLLSASR--RATTLEAVLEEMA---------GCATRLELGGPR-----
MSMEG_4820|M.smegmatis_MC2_155 TWLHVTIPGDSLAHALETIEGFGK---------SVIAR------------
TH_3375|M.thermoresistible__bu PPQFVAGTPEQCVAQLRPWWRILARLPEHVQPHLILGMTFPGVSREATFE
Mflv_1590|M.gilvum_PYR-GCK ------------------------
Mvan_5167|M.vanbaalenii_PYR-1 ------------------------
Mb3106c|M.bovis_AF2122/97 ------------------------
Rv3079c|M.tuberculosis_H37Rv ------------------------
MAV_2133|M.avium_104 YLKRVGEVV--LPEALGH------
MMAR_3375|M.marinum_M SLKLLEQTMPKLKAAIAALD----
MUL_4877|M.ulcerans_Agy99 SLRLLAEEVLPRVADIPDSATTKP
MAB_0366|M.abscessus_ATCC_1997 ------------------------
MSMEG_4820|M.smegmatis_MC2_155 ------------------------
TH_3375|M.thermoresistible__bu SVRLLAREVVPALNAEE-------