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PKVTVEPDWFFYTAACLGQAASSLAGAVSTATGDGGLLYSQKMAGNDAKGSGWGTPYDASAKTVLHGAAS LVSAWSSMAQKVHQAGVNHQFAEWEAGRRGYPGPNSAPPKPPISSSVANTPPSAVGDNGPGLDDFIPGLV DAVGEPCPNGDYEKLGRMAPAWTALGNAINRSGSEWIAKIHRPDPSMTDAMPFYDAIMKLNEPANAIAGD AMQMASFTSTFGTAIHAFREASAKAIDDLVLIIGLIGVATVVGTRIAGKKAVQVGGRLTAREVGETGKEI NGLIRALEPVVASMRTFVTALNPTMQGLLDQTTQFPAESYELQPDGTFKKTIRYFKLEKWMAWQRYLLRG GDMDIDTWSDYYDRIRQNQADGDAFDKLAADVMGYDKGEGWTPQFGSKKEDYDKVPLPGRHWDWGNPDLQ QVAEHKKGKLDSDQMVTDREVLERTRWTVTYNINANHQYTKAEEDWLAQMQKAFPGRFIVNRIEF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4829c | - | - | 100% (486) | hypothetical protein MAB_4829c |
| M. abscessus ATCC 19977 | MAB_3114 | - | 1e-10 | 26.15% (283) | hypothetical protein MAB_3114 |
| M. abscessus ATCC 19977 | MAB_4465 | - | 4e-10 | 27.59% (174) | hypothetical protein MAB_4465 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3933c | - | 3e-10 | 26.34% (224) | hypothetical protein Mb3933c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3903c | - | 3e-10 | 26.34% (224) | hypothetical protein Rv3903c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3072 | - | 3e-07 | 27.17% (173) | hypothetical protein MMAR_3072 |
| M. avium 104 | MAV_4644 | - | 2e-09 | 29.01% (162) | hypothetical protein MAV_4644 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2318 | - | 4e-08 | 20.99% (362) | hypothetical protein MUL_2318 |
| M. vanbaalenii PYR-1 | Mvan_1118 | - | 2e-15 | 27.38% (252) | hypothetical protein Mvan_1118 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3933c|M.bovis_AF2122/97 ------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLT--AALAGCAGM
Rv3903c|M.tuberculosis_H37Rv ------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLT--AALAGCAGM
MAV_4644|M.avium_104 ------MAPLACDPTALDHAGATVVAAGESLGSVISTLT--AALAGTSGM
MMAR_3072|M.marinum_M ------MAPLSVDPEALSGAGSAVAAAGDALAAALSSLT--TGFSANT--
MUL_2318|M.ulcerans_Agy99 MGKNPGVAPLSVDPEALSGAGSAVAAAGDALAAALSSLT--TGFSANT--
Mvan_1118|M.vanbaalenii_PYR-1 ------MTVQDVDPDTFYAVGKGLFEKAGKLYDAFNVNV--AILGDTAAM
MAB_4829c|M.abscessus_ATCC_199 ------MPKVTVEPDWFFYTAACLGQAASSLAGAVSTATGDGGLLYSQKM
:. :* : .. : . * ... . :
Mb3933c|M.bovis_AF2122/97 AGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNYSLAE
Rv3903c|M.tuberculosis_H37Rv AGDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNYSLAE
MAV_4644|M.avium_104 AGDDPVGAALGRRYDGAAAKLIQAMADTRNGLCSIGDGVRMSAHNYAVAE
MMAR_3072|M.marinum_M -GQDAAGEVFGLAYQDAAESLVKAAGAGINALRHNGAKIQLSASNYSAAE
MUL_2318|M.ulcerans_Agy99 -GQDTAGEVFGLAYQDAAESLVKAAGAGINALRHNGAKIQLSASNYSAAE
Mvan_1118|M.vanbaalenii_PYR-1 AGTDDTGTAWAASYDQRVGEILAAVNDLTRAMDNYGGVVIQAGYNHAVAE
MAB_4829c|M.abscessus_ATCC_199 AGNDAKGSGWGTPYDASAKTVLHGAASLVSAWSSMAQKVHQAGVNHQFAE
* * * . *: . :: . . . : :. *: **
Mb3933c|M.bovis_AF2122/97 AMSDVAG--RAAPLPAPPPSGCVGVGAPPSAVGGGGGAPKGWG-WVAPYI
Rv3903c|M.tuberculosis_H37Rv AMSDVAG--RAAPLPAPPPSGCVGVGAPPSAVGGGGGAPKGWG-WVAPYI
MAV_4644|M.avium_104 AMSDLAG--RASALPAPQVTGPLTVGAPPSAVGHGSGAPAGWG-WVAPSI
MMAR_3072|M.marinum_M AASTLGG--GAGVLPAPSEPAQFTAPGAPGTLGSGVLAPALWS-VVEAFV
MUL_2318|M.ulcerans_Agy99 AASTLGG--GAGVLPAPSEPAQFTAPGAPGTLGSGVLAPALWS-VVEAFV
Mvan_1118|M.vanbaalenii_PYR-1 HNATLGNT-EPAPVKPPEPVSAAGVLTAPPSAGGPGSGLLDNV-GLMQQV
MAB_4829c|M.abscessus_ATCC_199 WEAGRRGYPGPNSAPPKPPISSSVANTPPSAVGDNGPGLDDFIPGLVDAV
: . . . . . .* : * . : :
Mb3933c|M.bovis_AF2122/97 GMIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAG-PMGVIRAQQLPEA
Rv3903c|M.tuberculosis_H37Rv GMIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAG-PMGVIRAQQLPEA
MAV_4644|M.avium_104 GMIWPTGDSAKLRAAAAAWATAGANFMAAETAAGGG-TMAAIGAQQIPEG
MMAR_3072|M.marinum_M GDLWPNGDVAGLHAAAGHWRDFAAALNGVQGALNS--PKSVVAGQDIPEG
MUL_2318|M.ulcerans_Agy99 GDLWPNGDVAGLHAAAGHWRDFAAALNGVQGALNS--PKSVVAGQDIPEG
Mvan_1118|M.vanbaalenii_PYR-1 GVPVPDGDTAKVSKAGEAWDRLATVYQTTTVAEGLGVDARAFRETRSPEV
MAB_4829c|M.abscessus_ATCC_199 GEPCPNGDYEKLGRMAPAWTALGNAINRSGSEWIAK---IHRPDPSMTDA
* * ** : . * . .:
Mb3933c|M.bovis_AF2122/97 GLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAVHAAVLDLLARIC
Rv3903c|M.tuberculosis_H37Rv GLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAVHAAVLDLLARIC
MAV_4644|M.avium_104 AAINKALADASSATADVARQCQTIAAQLNSYAAKVDQVHAAILDLLSRIC
MMAR_3072|M.marinum_M AQIQQVLSAIGSDLAGVGAQCQKLAGALDDFADEVADTQDAIRDLLDRFG
MUL_2318|M.ulcerans_Agy99 VQIQQVLSAIGSDLAGVGAQCRKLAGALDDFADEVADTQDAIRDLLDRFG
Mvan_1118|M.vanbaalenii_PYR-1 EYIVSDLDELRQATSAVLDGCAELAQSCRDYKAALDDLRSTLERILEDLA
MAB_4829c|M.abscessus_ATCC_199 MPFYDAIMKLNEPANAIAGDAMQMASFTSTFGTAIHAFREASAKAIDDLV
: . : : . :* : : : : : :
Mb3933c|M.bovis_AF2122/97 DPLTGIKEVWEFLTDQDEDEIQRIAHDIAV-VVDQFSGEVDALAAEITAV
Rv3903c|M.tuberculosis_H37Rv DPLTGIKEVWEFLTDQDEDEIQRIAHDIAV-VVDQFSGEVDALAAEITAV
MAV_4644|M.avium_104 DPLTGIKEVWDLLTDEDEDEIKKIADDIRT-VVDNFGREADTLGGQIEAT
MMAR_3072|M.marinum_M SVSGLWNQVMAIFEGDALDEIKEIAEDIQA-VLSNLGRQARAQQQLMQQG
MUL_2318|M.ulcerans_Agy99 SVSGLWNQVVAIFEGDALDEIKEIAEDIRA-VLSNLGRQARAQQQLMQQG
Mvan_1118|M.vanbaalenii_PYR-1 VELAAT-----------------VAIGVAA-SFVSFGAGAVAATAKAAHS
MAB_4829c|M.abscessus_ATCC_199 LIIGLIGVATVVGTRIAGKKAVQVGGRLTAREVGETGKEINGLIRALEPV
:. : . . . .
Mb3933c|M.bovis_AF2122/97 VSHAEAVITAMADHAGKQWDRFL---HSNPVGVVIDGTGQQLKGFGEEAF
Rv3903c|M.tuberculosis_H37Rv VSHAEAVITAMADHAGKQWDRFL---HSNPVGVVIDGTGQQLKGFGEEAF
MAV_4644|M.avium_104 VSAVAAATENMSHWAGKEWDHFL---HGTPVGRALNQVGQAFKGVGEEGW
MMAR_3072|M.marinum_M MQAIDGLVVGMQRYVRGQLTQFLGQDVGNPLATVFDTYTNTQEGVFKAAV
MUL_2318|M.ulcerans_Agy99 MQAIDGLVVGMQRYVRGQLTQLLGQDVGNPVATVFDTYTNTQEGVFKAAV
Mvan_1118|M.vanbaalenii_PYR-1 VTKFA---------------------------------------------
MAB_4829c|M.abscessus_ATCC_199 VASMRTFVTALN---------------------------PTMQGLLDQTT
:
Mb3933c|M.bovis_AF2122/97 GMAKDSWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESW
Rv3903c|M.tuberculosis_H37Rv GMAKDSWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENAPGVVESW
MAV_4644|M.avium_104 GFLKGLYEVSPNRMLLDPVGYGKTMAGMVEGAGTLVGLGPDGVPGAFDAW
MMAR_3072|M.marinum_M GMVEGIEQLNPQRFLIDPQGAAETWKAMTKTGLINHLLNPE---EAVAAD
MUL_2318|M.ulcerans_Agy99 GMVEGIEQLNPQRFLIDPQGAAETWKAMTKTGLINHLLNPE---EAVAAD
Mvan_1118|M.vanbaalenii_PYR-1 ------------RIIAEAIGAWRISKNISKG-------------------
MAB_4829c|M.abscessus_ATCC_199 QFPAESYELQPDGTFKKTIRYFKLEKWMAWQR------------------
.. . :
Mb3933c|M.bovis_AF2122/97 KQFGKSLIHWDEWTTN-PNEALGKTVFDAATLALPGGPLSKLGSKGRDIL
Rv3903c|M.tuberculosis_H37Rv KQFGKSLIHWDEWTTN-PNEALGKTVFDAATLALPGGPLSKLGSKGRDIL
MAV_4644|M.avium_104 KALGKDVTHWDEWGSN-PAEALGKSTFDVATLALPGGPLSKLGKFGHSAA
MMAR_3072|M.marinum_M KEMVKGLLHLEDWRRDRPGLGFGGNLFDVATLFVPGAGGAGAGAKGAAGA
MUL_2318|M.ulcerans_Agy99 KEMVKGLLHLEDWRRDRPGLGFGGNLFDVATLFVPGAGGAGAGAKGAAGA
Mvan_1118|M.vanbaalenii_PYR-1 ----------------------VKSAHDIAGVRTKLQRIKNLGRKNK---
MAB_4829c|M.abscessus_ATCC_199 -------------------YLLRGGDMDIDTWSDYYDRIRQNQADGD---
* .
Mb3933c|M.bovis_AF2122/97 AGVRGLKER-LEPTTPHLEPPATPPRPGPQPPRIEPPESGHPAP-APAAK
Rv3903c|M.tuberculosis_H37Rv AGVRGLKER-LEPTTPHLEPPATPPRPGPQPPRIEPPESGHPAP-APAAK
MAV_4644|M.avium_104 DALKGLKKPPGVPKPPEVKPPAAPKAPDSG----QPAPSGKPGPVAPSGK
MMAR_3072|M.marinum_M ARAAEVGGEAADAAAAVGRGGRLAGEVGDLAGAGRTLGDIGKTGRGLTED
MUL_2318|M.ulcerans_Agy99 ARAAEVGGEAADAAAAAGRGGRLAGEVGDLAGAGRTLGDIGKTGRGLTED
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4829c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 PAPVPANGPLPHSPTESKPPPVDRP---AEPVAPSSASAGQPRVSAATTP
Rv3903c|M.tuberculosis_H37Rv PAPVPANGPLPHSPTESKPPPVDRP---AEPVAPSSASAGQPRVSAATTP
MAV_4644|M.avium_104 PAPGPADGPLPHSPTESKPPAGGTPP-AAEPPKPTAAPHSGEPKPIATPP
MMAR_3072|M.marinum_M LANLGGDLPKADPPVGGRPVALPPPKPAGAPAEPTPRPVESVPPGKPALE
MUL_2318|M.ulcerans_Agy99 LANLGGDLPKADPPVGGRPVALPPPKPAGAPIEPTPRPVESVPPGKPALE
Mvan_1118|M.vanbaalenii_PYR-1 --------------PEEKPPAPTPPPPPGVPAGWTARPADNGMGTVYQQP
MAB_4829c|M.abscessus_ATCC_199 ------------AFDKLAADVMGYDKGEGWTPQFGSKKEDYDKVPLPGRH
. . . .
Mb3933c|M.bovis_AF2122/97 GTHVPHGLPQPGEHVPAQAPPATTLLGGPPVESAPATAHQPQWATTPAAP
Rv3903c|M.tuberculosis_H37Rv GTHVPHGLPQPGEHVPAQAPPATTLLGGPPVESAPATAHQPQWATTPAAP
MAV_4644|M.avium_104 ESVGKPVTPAPAEGAPAQPHEPVSARVPPTVPAADTPAPSAPAASMSAAS
MMAR_3072|M.marinum_M APSGAPGSVVPGRSEPAFGPHDPASAPVAGSHPAATAVTPGERVSPVTPH
MUL_2318|M.ulcerans_Agy99 APSGAPGSVVPGRSEPAFGPHDPASAPVAGSHPAATAVTPGERLSPVTPH
Mvan_1118|M.vanbaalenii_PYR-1 GSLGNSNS--------MRIMEPGADPRYPNGYVKFTNEHNQPINLDGKPG
MAB_4829c|M.abscessus_ATCC_199 WDWGNPDLQQVAEHKKGKLDSDQMVTDREVLERTRWTVTYNINANHQYTK
.
Mb3933c|M.bovis_AF2122/97 AAAPHSTPGGVHSTESGPHGRSLSAHGSEPTHDGASH-GSGHGSGSEPPG
Rv3903c|M.tuberculosis_H37Rv AAAPHSTPGGVHSTESGPHGRSLSAHGSEPTHDGASH-GSGHGSGSEPPG
MAV_4644|M.avium_104 GPPMPPTP-SLPEPASLPSGPSGDLPAETPPTAGIPHSGEPSAPSSVPPH
MMAR_3072|M.marinum_M VGEPARAPGVPVGAAAGPVPAGAHSAPAAIPAAPGAHVMTGAGRPAELSA
MUL_2318|M.ulcerans_Agy99 VGEPARAPGVPVGAAAGPVPAGAHSAPAAIPAAPGAHVMTGAGRPAELSA
Mvan_1118|M.vanbaalenii_PYR-1 TRADTHIPRNPDGTYPIPKGWP----------------------------
MAB_4829c|M.abscessus_ATCC_199 AEEDWLAQMQKAFPGRFIVNRIEF--------------------------
.
Mb3933c|M.bovis_AF2122/97 LHAP--HREQQLAMHS-----NEPAGEGWHRLSDEAVDPQYGEPLS---R
Rv3903c|M.tuberculosis_H37Rv LHAP--HREQQLAMHS-----NEPAGEGWHRLSDEAVDPQYGEPLS---R
MAV_4644|M.avium_104 FPDTPTHGLGDGGAHGPP--ESDPKNANGHGPHDASLDSGSDHHLP---L
MMAR_3072|M.marinum_M PHGGVPQGLGDAGPSGGHPHGLPPHGGGPHGPGDASHGARHAEPPRDGTA
MUL_2318|M.ulcerans_Agy99 PHGGVPHGLGDAGPSGGHPHGLPPHGGGPHGPGDASHGARHAEPPRDGTA
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4829c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 HWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQGQPYTQERYQERFNSV
Rv3903c|M.tuberculosis_H37Rv HWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQGQPYTQERYQERFNSV
MAV_4644|M.avium_104 HPLDSDDLAALAHYTGPGYQELN-----FALREGALDVSQQARVDALQKA
MMAR_3072|M.marinum_M HGTADGGDAHGDDVSGHGLSAEKRDEIIAMPKGSRPDPSEYLSPEYIQGH
MUL_2318|M.ulcerans_Agy99 HGTADGGDAHGDDVSGHGLSAEKRDEIIAMRKGSRPDPSEYLSPEYIQGH
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4829c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 GPWGQQYSNFPPNNGAVPGTRIAYTNLEKFLSDYGPQLDRIGGDQGKYLA
Rv3903c|M.tuberculosis_H37Rv GPWGQQYSNFPPNNGAVPGTRIAYTNLEKFLSDYGPQLDRIGGDQGKYLA
MAV_4644|M.avium_104 LEKLPVYEGAVVRGTNLPADVLEQYRPGEVITEAAFTSTSTDHTVAQSSA
MMAR_3072|M.marinum_M LDRFTDGATRFMPESNLDKYGIAQRDGTSFVMPKSEADAMIAGTGGDLRL
MUL_2318|M.ulcerans_Agy99 LDRFTGGATRFMPESNLDKYGIAQRDGTSFVMPKSEADAMIAGTGGDLRL
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4829c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 IMEHG-RPASWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSEVAPGCGQ
Rv3903c|M.tuberculosis_H37Rv IMEHG-RPASWEQRALHVTSLRDPYHAYTIDWLPEGWFIEVSEVAPGCGQ
MAV_4644|M.avium_104 FAGNT-EFRIWSTTGRDVSSVSMYPDEKEILFPAGSKFYVVSKTVD--PQ
MMAR_3072|M.marinum_M MEEELGLPEGFLDSNQIVRIDIEDPRQFNLRIPSGNEAGANEQWIPGGRL
MUL_2318|M.ulcerans_Agy99 MEEELGLPEGFLDSNQIVRIDIEDPRQFNLRIPSGNEAGANEQWIPGGLL
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4829c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 PGGSIQVRIFDHQNEM--RKVEELIRRGVLRQ
Rv3903c|M.tuberculosis_H37Rv PGGSIQVRIFDHQNEM--RKVEELIRRGVLRQ
MAV_4644|M.avium_104 TG----------------RTIIEMIER-----
MMAR_3072|M.marinum_M PTGASEAVVDGGKIPQGDYTVTDVFEEK----
MUL_2318|M.ulcerans_Agy99 PTGASEAVVDGGKVPQGDYTVTDVFEEK----
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------
MAB_4829c|M.abscessus_ATCC_199 --------------------------------