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TVQDVDPDTFYAVGKGLFEKAGKLYDAFNVNVAILGDTAAMAGTDDTGTAWAASYDQRVGEILAAVNDLT RAMDNYGGVVIQAGYNHAVAEHNATLGNTEPAPVKPPEPVSAAGVLTAPPSAGGPGSGLLDNVGLMQQVG VPVPDGDTAKVSKAGEAWDRLATVYQTTTVAEGLGVDARAFRETRSPEVEYIVSDLDELRQATSAVLDGC AELAQSCRDYKAALDDLRSTLERILEDLAVELAATVAIGVAASFVSFGAGAVAATAKAAHSVTKFARIIA EAIGAWRISKNISKGVKSAHDIAGVRTKLQRIKNLGRKNKPEEKPPAPTPPPPPGVPAGWTARPADNGMG TVYQQPGSLGNSNSMRIMEPGADPRYPNGYVKFTNEHNQPINLDGKPGTRADTHIPRNPDGTYPIPKGWP *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1118 | - | - | 100% (421) | hypothetical protein Mvan_1118 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3933c | - | 2e-17 | 27.47% (233) | hypothetical protein Mb3933c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3903c | - | 2e-17 | 27.47% (233) | hypothetical protein Rv3903c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3114 | - | 3e-20 | 28.99% (276) | hypothetical protein MAB_3114 |
| M. marinum M | MMAR_5464 | - | 7e-10 | 23.40% (235) | ADP-ribosyltransferse |
| M. avium 104 | MAV_4644 | - | 1e-16 | 28.14% (231) | hypothetical protein MAV_4644 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2318 | - | 3e-07 | 24.00% (225) | hypothetical protein MUL_2318 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3933c|M.bovis_AF2122/97 ------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAGCA-GMA
Rv3903c|M.tuberculosis_H37Rv ------MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAGCA-GMA
MMAR_5464|M.marinum_M ------MAPLAVDPAALDGAGAAVVAAGEGLEPVIASLSAVLAGCA-GMA
MAV_4644|M.avium_104 ------MAPLACDPTALDHAGATVVAAGESLGSVISTLTAALAGTS-GMA
MUL_2318|M.ulcerans_Agy99 MGKNPGVAPLSVDPEALSGAGSAVAAAGDALAAALSSLTTGFS----ANT
Mvan_1118|M.vanbaalenii_PYR-1 ------MTVQDVDPDTFYAVGKGLFEKAGKLYDAFNVNVAILGDTA-AMA
MAB_3114|M.abscessus_ATCC_1997 -------MPVVVESAAYYAAANTCYKLSTDVQAAFKPLSRVLTLETSGMA
:. : .. . : .: : . :
Mb3933c|M.bovis_AF2122/97 GDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNYSLAEA
Rv3903c|M.tuberculosis_H37Rv GDDPAGAVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNYSLAEA
MMAR_5464|M.marinum_M GDDPVGAAVGRGYDRAAAKVFSAMAATRNGLCSIGDGVRMSAHNYSLAEA
MAV_4644|M.avium_104 GDDPVGAALGRRYDGAAAKLIQAMADTRNGLCSIGDGVRMSAHNYAVAEA
MUL_2318|M.ulcerans_Agy99 GQDTAGEVFGLAYQDAAESLVKAAGAGINALRHNGAKIQLSASNYSAAEA
Mvan_1118|M.vanbaalenii_PYR-1 GTDDTGTAWAASYDQRVGEILAAVNDLTRAMDNYGGVVIQAGYNHAVAEH
MAB_3114|M.abscessus_ATCC_1997 GGYQAVKAWSSGYDNRAAALTTATTEYARALQRLGDILTAAGYNWAIADW
* . . . *: . : * ..: * : :. * : *:
Mb3933c|M.bovis_AF2122/97 MSDVAG-RAAPLPAPPPSGCVGVGAPPSAVGGGGGAPKG-----------
Rv3903c|M.tuberculosis_H37Rv MSDVAG-RAAPLPAPPPSGCVGVGAPPSAVGGGGGAPKG-----------
MMAR_5464|M.marinum_M MSDVTR-RAAALPAPTLTTCIVAASAPSAVGTADSAPAG-----------
MAV_4644|M.avium_104 MSDLAG-RASALPAPQVTGPLTVGAPPSAVGHGSGAPAG-----------
MUL_2318|M.ulcerans_Agy99 ASTLGG-GAGVLPAPSEPAQFTAPGAPGTLGSGVLAPAL-----------
Mvan_1118|M.vanbaalenii_PYR-1 NATLGNTEPAPVKPPEPVSAAGVLTAPPSAGGPGSGLLD-----------
MAB_3114|M.abscessus_ATCC_1997 RANRDPNKGTGPACPRTIPSELPYGADVVVGVASSKHNGPGLESDVPDLY
: * . *
Mb3933c|M.bovis_AF2122/97 WGWVAPYIGMIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGPMGVIR
Rv3903c|M.tuberculosis_H37Rv WGWVAPYIGMIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGPMGVIR
MMAR_5464|M.marinum_M WGWIAPYIGMIWPTGNLSKLRTAASEWTAEGTKFALVETQLTAGPLGAIR
MAV_4644|M.avium_104 WGWVAPSIGMIWPTGDSAKLRAAAAAWATAGANFMAAETAAGGGTMAAIG
MUL_2318|M.ulcerans_Agy99 WSVVEAFVGDLWPNGDVAGLHAAAGHWRDFAAALNGVQGALNS-PKSVVA
Mvan_1118|M.vanbaalenii_PYR-1 NVGLMQQVGVPVPDGDTAKVSKAGEAWDRLATVYQTTTVAEGLGVDARAF
MAB_3114|M.abscessus_ATCC_1997 KKVVAQVAGGEIPDGDTNKLDSAAKAWKTFADNDAISRGESDLRLAASAL
: * * *: : *. * . .
Mb3933c|M.bovis_AF2122/97 AQQ-LPEAGLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAVHAAV
Rv3903c|M.tuberculosis_H37Rv AQQ-LPEAGLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAVHAAV
MMAR_5464|M.marinum_M SQQ-LPESGLIERAFTDAYVSTTSVVGQCQTIAAQLDRYADQIDEVHAAI
MAV_4644|M.avium_104 AQQ-IPEGAAINKALADASSATADVARQCQTIAAQLNSYAAKVDQVHAAI
MUL_2318|M.ulcerans_Agy99 GQD-IPEGVQIQQVLSAIGSDLAGVGAQCRKLAGALDDFADEVADTQDAI
Mvan_1118|M.vanbaalenii_PYR-1 RETRSPEVEYIVSDLDELRQATSAVLDGCAELAQSCRDYKAALDDLRSTL
MAB_3114|M.abscessus_ATCC_1997 SNFHAPDIPNLSEHLTTLSTSAGRIKLAASDLATSTTAHYAALSQLRSDM
: *: : : : . :* . : : :
Mb3933c|M.bovis_AF2122/97 LDLLARICDPLTGIKEVWEFLTDQDEDEIQRIAHDIAVVVDQFSGEVDAL
Rv3903c|M.tuberculosis_H37Rv LDLLARICDPLTGIKEVWEFLTDQDEDEIQRIAHDIAVVVDQFSGEVDAL
MMAR_5464|M.marinum_M LDLLARICDPLTGIKEVWEVLTGEDEDEIERIAHEIAAVVDHFAAEANAL
MAV_4644|M.avium_104 LDLLSRICDPLTGIKEVWDLLTDEDEDEIKKIADDIRTVVDNFGREADTL
MUL_2318|M.ulcerans_Agy99 RDLLDRFGSVSGLWNQVVAIFEGDALDEIKEIAEDIRAVLSNLGRQARAQ
Mvan_1118|M.vanbaalenii_PYR-1 ERILEDLAVELAAT-----------------VAIGVAASFVSFGAGAVAA
MAB_3114|M.abscessus_ATCC_1997 QFAIATTLG--------------------VGLAAIAAIAVITRGRATAGG
: :* . . .
Mb3933c|M.bovis_AF2122/97 AAEITAVVSHAEAVITAMADHAGKQWDRFL---HSNPVGVVIDGTGQQLK
Rv3903c|M.tuberculosis_H37Rv AAEITAVVSHAEAVITAMADHAGKQWDRFL---HSNPVGVVIDGTGQQLK
MMAR_5464|M.marinum_M SAQFNAALVHADTVLDTMARHAAREWDQFL---HGNPVGAIVDFAGQRLK
MAV_4644|M.avium_104 GGQIEATVSAVAAATENMSHWAGKEWDHFL---HGTPVGRALNQVGQAFK
MUL_2318|M.ulcerans_Agy99 QQLMQQGMQAIDGLVVGMQRYVRGQLTQLLGQDVGNPVATVFDTYTNTQE
Mvan_1118|M.vanbaalenii_PYR-1 TAKAAHSVTKFA--------------------------------------
MAB_3114|M.abscessus_ATCC_1997 AEIAATAVDACASSLAAC--------------------------------
:
Mb3933c|M.bovis_AF2122/97 GFGEEAFGMAKDSWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENA
Rv3903c|M.tuberculosis_H37Rv GFGEEAFGMAKDSWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENA
MMAR_5464|M.marinum_M GLGEAAWGLAETALTYNQIRALLDPLGYARDVGSMAQGMAPLVGLGDDHA
MAV_4644|M.avium_104 GVGEEGWGFLKGLYEVSPNRMLLDPVGYGKTMAGMVEGAGTLVGLGPDGV
MUL_2318|M.ulcerans_Agy99 GVFKAAVGMVEGIEQLNPQRFLIDPQGAAETWKAMTKTGLINHLLNPE--
Mvan_1118|M.vanbaalenii_PYR-1 -------------------RIIAEAIGAWRISKNISKG------------
MAB_3114|M.abscessus_ATCC_1997 ------------------IRPFLTTLGGITFNAEAVTAAG----------
* . *
Mb3933c|M.bovis_AF2122/97 PGVVESWKQFGKSLIHWDEWTTN-PNEALGKTVFDAATLALPGGPLSKLG
Rv3903c|M.tuberculosis_H37Rv PGVVESWKQFGKSLIHWDEWTTN-PNEALGKTVFDAATLALPGGPLSKLG
MMAR_5464|M.marinum_M PSVLESWKQLGKEVTHWDDWSRS-PGEALGKSEFDLANLFLPGGPISKAA
MAV_4644|M.avium_104 PGAFDAWKALGKDVTHWDEWGSN-PAEALGKSTFDVATLALPGGPLSKLG
MUL_2318|M.ulcerans_Agy99 -EAVAADKEMVKGLLHLEDWRRDRPGLGFGGNLFDVATLFVPGAGGAGAG
Mvan_1118|M.vanbaalenii_PYR-1 -----------------------------VKSAHDIAGVRTKLQRIKNLG
MAB_3114|M.abscessus_ATCC_1997 -----------------------------LGAIIGLSIATITGETVVYSN
. :
Mb3933c|M.bovis_AF2122/97 SKGRDILAGVRGLKERLEPTTPHLEPPATPP-----------------RP
Rv3903c|M.tuberculosis_H37Rv SKGRDILAGVRGLKERLEPTTPHLEPPATPP-----------------RP
MMAR_5464|M.marinum_M SKGRDLADGLQGLKARLRPNEMGEPNPLKRPDAS--------------AA
MAV_4644|M.avium_104 KFGHSAADALKGLKK---PPGVPKPPEVKPP-----------------AA
MUL_2318|M.ulcerans_Agy99 AKGAAGAARAAEVGGEAADAAAAAGRGGRLAGEVGDLAGAGRTLGDIGKT
Mvan_1118|M.vanbaalenii_PYR-1 RKNK----------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 GPQPPRIEPPESGHP-APAPAAKPAPVPANGP-LPHSPTESKPPPVDRP-
Rv3903c|M.tuberculosis_H37Rv GPQPPRIEPPESGHP-APAPAAKPAPVPANGP-LPHSPTESKPPPVDRP-
MMAR_5464|M.marinum_M EHTPPSTMPQQEAKQPAAAPQPKPLR-PSDGHGLPHSPTESKAPPVDKPA
MAV_4644|M.avium_104 PKAPDSGQPAPSGKPGPVAPSGKPAPGPADGP-LPHSPTESKPPAGGTPP
MUL_2318|M.ulcerans_Agy99 GRGLTEDLANLGGDLPKADPPVGGRPVALPPPKPAGAPIEPTPRPVESVP
Mvan_1118|M.vanbaalenii_PYR-1 -------------------------------------PEEKPPAPTPPPP
MAB_3114|M.abscessus_ATCC_1997 -----------------------------------YKPPGDAFDKTGAKS
*
Mb3933c|M.bovis_AF2122/97 -AEPVAPSSASAGQPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLG
Rv3903c|M.tuberculosis_H37Rv -AEPVAPSSASAGQPRVSAATTPGTHVPHGLPQPGEHVPAQAPPATTLLG
MMAR_5464|M.marinum_M TGEPVKP-AGAQLGEAR--APGAAARGEKELPAQAEHS-EQINTPVSAPG
MAV_4644|M.avium_104 AAEPPKPTAAPHSGEPKPIATPPESVGKPVTPAPAEGAPAQPHEPVSARV
MUL_2318|M.ulcerans_Agy99 PGKPALEAPSGAPGSVVPGRSEPAFGPHDPASAPVAGSHPAATAVTPGER
Mvan_1118|M.vanbaalenii_PYR-1 PGVPAGWTARPADNGMGTVYQQPGSLGN----SNSMRIMEPGADPRYPNG
MAB_3114|M.abscessus_ATCC_1997 PGYPGDYPAGSLPREFVPPKDGPKWVPNPNPKGNRFGWLDADGNVWVPTG
. * . .
Mb3933c|M.bovis_AF2122/97 GPPVESAPATAHQPQWATTPAAPAAAPHSTPGGVHSTESGPHGRSLSAHG
Rv3903c|M.tuberculosis_H37Rv GPPVESAPATAHQPQWATTPAAPAAAPHSTPGGVHSTESGPHGRSLSAHG
MMAR_5464|M.marinum_M P--VDGSDLDPTPARPHTSRAAPASAMP----HLAGSRSTPSDVCG----
MAV_4644|M.avium_104 PPTVPAADTPAPSAPAASMSAASGPPMPPTP-SLPEPASLPSGPSGDLPA
MUL_2318|M.ulcerans_Agy99 LSPVTPHVGEPARAPGVPVGAAAGPVPAGAHSAPAAIPAAPGAHVMTGAG
Mvan_1118|M.vanbaalenii_PYR-1 YVKFTNEHNQPINLDGKPGTRADTHIPRNPDGTYPIPKGWP---------
MAB_3114|M.abscessus_ATCC_1997 KGGLAHGGPHWDVQDPKTGKHENVPPPLPEGEGK----------------
. .
Mb3933c|M.bovis_AF2122/97 SEPTHDGASHGSGHGSGSEPPGLHAPHREQQLAMHSNEPAGEGWHRLSDE
Rv3903c|M.tuberculosis_H37Rv SEPTHDGASHGSGHGSGSEPPGLHAPHREQQLAMHSNEPAGEGWHRLSDE
MMAR_5464|M.marinum_M -----PNVVS-----EGGSPGGHSTPAALDEV-------GGAPGASAPGE
MAV_4644|M.avium_104 ETPPTAGIPH-----SGEPSAPSSVPPHFPDTPTHGLGDGGAHGPPESDP
MUL_2318|M.ulcerans_Agy99 RPAELSAPHGGVPHGLGDAGPSGGHPHGLPPHGGGPHGPGDASHGARHAE
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 AVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQGQPY
Rv3903c|M.tuberculosis_H37Rv AVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPNAPFGRDPQGQPY
MMAR_5464|M.marinum_M YHGTGGGPGDHGTADGGQSLIIVDGLHADDLSALADYTGSGYLDLNNALR
MAV_4644|M.avium_104 KNANGHGPHDASLDSGSDHHLPLHPLDSDDLAALAHYTGPGYQELNFALR
MUL_2318|M.ulcerans_Agy99 PPRDGTAHGTADGGDAHGDDVSGHGLSAEKRDEIIAMRKGSRPDPSEYLS
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 TQERYQERFNSVGPWGQQYSNFPPNNGAVP-GTRIAYTNLEKFLSDYGPQ
Rv3903c|M.tuberculosis_H37Rv TQERYQERFNSVGPWGQQYSNFPPNNGAVP-GTRIAYTNLEKFLSDYGPQ
MMAR_5464|M.marinum_M SDILDASLNARVAALNSALQKLPTYDGTVVRGTDLPPEVVAQYLPGEVIT
MAV_4644|M.avium_104 EGALDVSQQARVDALQKALEKLPVYEGAVVRGTNLPADVLEQYRPGEVIT
MUL_2318|M.ulcerans_Agy99 PEYIQGHLDRFTGGATRFMPESNLDKYGIAQRDGTSFVMPKSEADAMIAG
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 LDRIGGDQGKYLAIMEHGRPASWEQRALHVTSLRDPYHAYTIDWLPEGWF
Rv3903c|M.tuberculosis_H37Rv LDRIGGDQGKYLAIMEHGRPASWEQRALHVTSLRDPYHAYTIDWLPEGWF
MMAR_5464|M.marinum_M EVAFLSTTTDPAVAQSPTFAGNVEFRIVSRTGR----DVSSVSMFPD---
MAV_4644|M.avium_104 EAAFTSTSTDHTVAQSSAFAGNTEFRIWSTTGR----DVSSVSMYPD---
MUL_2318|M.ulcerans_Agy99 TGGDLRLMEEELGLPEGFLDSNQIVRIDIEDPR------QFNLRIPSGNE
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 IEVSEVAPGCGQPGGSIQVRIFDH---QNEMRKVEELIRRGVLRQ
Rv3903c|M.tuberculosis_H37Rv IEVSEVAPGCGQPGGSIQVRIFDH---QNEMRKVEELIRRGVLRQ
MMAR_5464|M.marinum_M --EREILFPAG-TKFYVIDKTLDA---LTG-RTIIDMIER-----
MAV_4644|M.avium_104 --EKEILFPAG-SKFYVVSKTVDP---QTG-RTIIEMIER-----
MUL_2318|M.ulcerans_Agy99 AGANEQWIPGGLLPTGASEAVVDGGKVPQGDYTVTDVFEEK----
Mvan_1118|M.vanbaalenii_PYR-1 ---------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 ---------------------------------------------