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VPVVVESAAYYAAANTCYKLSTDVQAAFKPLSRVLTLETSGMAGGYQAVKAWSSGYDNRAAALTTATTEY ARALQRLGDILTAAGYNWAIADWRANRDPNKGTGPACPRTIPSELPYGADVVVGVASSKHNGPGLESDVP DLYKKVVAQVAGGEIPDGDTNKLDSAAKAWKTFADNDAISRGESDLRLAASALSNFHAPDIPNLSEHLTT LSTSAGRIKLAASDLATSTTAHYAALSQLRSDMQFAIATTLGVGLAAIAAIAVITRGRATAGGAEIAATA VDACASSLAACIRPFLTTLGGITFNAEAVTAAGLGAIIGLSIATITGETVVYSNYKPPGDAFDKTGAKSP GYPGDYPAGSLPREFVPPKDGPKWVPNPNPKGNRFGWLDADGNVWVPTGKGGLAHGGPHWDVQDPKTGKH ENVPPPLPEGEGK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3114 | - | - | 100% (433) | hypothetical protein MAB_3114 |
| M. abscessus ATCC 19977 | MAB_4829c | - | 1e-10 | 26.15% (283) | hypothetical protein MAB_4829c |
| M. abscessus ATCC 19977 | MAB_4465 | - | 3e-05 | 23.50% (234) | hypothetical protein MAB_4465 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3933c | - | 1e-10 | 24.72% (360) | hypothetical protein Mb3933c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3903c | - | 1e-10 | 24.72% (360) | hypothetical protein Rv3903c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_5464 | - | 6e-06 | 24.35% (230) | ADP-ribosyltransferse |
| M. avium 104 | MAV_2415 | - | 6e-06 | 21.33% (225) | hypothetical protein MAV_2415 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1118 | - | 4e-20 | 28.99% (276) | hypothetical protein Mvan_1118 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3933c|M.bovis_AF2122/97 MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAGCA-GMAGDDPAG
Rv3903c|M.tuberculosis_H37Rv MAPLAVDPAALDSAGGAVVAAGAGLGAVISSLTAALAGCA-GMAGDDPAG
MMAR_5464|M.marinum_M MAPLAVDPAALDGAGAAVVAAGEGLEPVIASLSAVLAGCA-GMAGDDPVG
MAV_2415|M.avium_104 MAPLAVDPEAMYAAGSAVAAIGDSLAANLTILTAGVS----AHTGVDRAG
Mvan_1118|M.vanbaalenii_PYR-1 MTVQDVDPDTFYAVGKGLFEKAGKLYDAFNVNVAILGDTA-AMAGTDDTG
MAB_3114|M.abscessus_ATCC_1997 -MPVVVESAAYYAAANTCYKLSTDVQAAFKPLSRVLTLETSGMAGGYQAV
*:. : ... . : : : . :* .
Mb3933c|M.bovis_AF2122/97 AVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNYSLAEAMSDVA-
Rv3903c|M.tuberculosis_H37Rv AVFGRSYDGSAAALVQAMSVARNGLCNLGDGVRMSAHNYSLAEAMSDVA-
MMAR_5464|M.marinum_M AAVGRGYDRAAAKVFSAMAATRNGLCSIGDGVRMSAHNYSLAEAMSDVT-
MAV_2415|M.avium_104 EVFGLGYQDSAESMLKAAAGVVNACRKCGALIQQGASNYSAAEAASTLG-
Mvan_1118|M.vanbaalenii_PYR-1 TAWAASYDQRVGEILAAVNDLTRAMDNYGGVVIQAGYNHAVAEHNATLGN
MAB_3114|M.abscessus_ATCC_1997 KAWSSGYDNRAAALTTATTEYARALQRLGDILTAAGYNWAIADWRANRDP
. . .*: . : * .. * : .. * : *: :
Mb3933c|M.bovis_AF2122/97 GRAAPLPAPPPSGCVGVGAPPSAVGGGGGAP-----------KGWGWVAP
Rv3903c|M.tuberculosis_H37Rv GRAAPLPAPPPSGCVGVGAPPSAVGGGGGAP-----------KGWGWVAP
MMAR_5464|M.marinum_M RRAAALPAPTLTTCIVAASAPSAVGTADSAP-----------AGWGWIAP
MAV_2415|M.avium_104 GGSGALPAPSAPADLAAPGPPGTWGKGEPPP-----------LLWAVIQA
Mvan_1118|M.vanbaalenii_PYR-1 TEPAPVKPPEPVSAAGVLTAPPSAGGPGSGL-----------LDNVGLMQ
MAB_3114|M.abscessus_ATCC_1997 NKGTGPACPRTIPSELPYGADVVVGVASSKHNGPGLESDVPDLYKKVVAQ
* . * :
Mb3933c|M.bovis_AF2122/97 YIGMIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGP-MGVIRAQQLP
Rv3903c|M.tuberculosis_H37Rv YIGMIWPNGDSTKLRAAAVAWRSAGTQFALTEIQSTAGP-MGVIRAQQLP
MMAR_5464|M.marinum_M YIGMIWPTGNLSKLRTAASEWTAEGTKFALVETQLTAGP-LGAIRSQQLP
MAV_2415|M.avium_104 LVSEVWPDGDEAGLHAAASRWHGFAAAMNGVQGTLNAS--KALFDSQQIP
Mvan_1118|M.vanbaalenii_PYR-1 QVGVPVPDGDTAKVSKAGEAWDRLATVYQTTTVAEGLGVDARAFRETRSP
MAB_3114|M.abscessus_ATCC_1997 VAGGEIPDGDTNKLDSAAKAWKTFADNDAISRGESDLRLAASALSNFHAP
. * *: : *. * . : : *
Mb3933c|M.bovis_AF2122/97 EAGLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAVHAAVLDLLAR
Rv3903c|M.tuberculosis_H37Rv EAGLIESAFADAYASTTAVVGQCHQLAAQLDAYAARIDAVHAAVLDLLAR
MMAR_5464|M.marinum_M ESGLIERAFTDAYVSTTSVVGQCQTIAAQLDRYADQIDEVHAAILDLLAR
MAV_2415|M.avium_104 EGEKIDHALAEIGAAAAAIGQQCDALARTVDEFADRVGHAQQAIRDLLHR
Mvan_1118|M.vanbaalenii_PYR-1 EVEYIVSDLDELRQATSAVLDGCAELAQSCRDYKAALDDLRSTLERILED
MAB_3114|M.abscessus_ATCC_1997 DIPNLSEHLTTLSTSAGRIKLAASDLATSTTAHYAALSQLRSDMQFAIAT
: : : :: : . :* . :. : : :
Mb3933c|M.bovis_AF2122/97 ICDPLTGIKEVWEFLTDQDEDEIQRIAHDIAVVVDQFSGEVDALAAEITA
Rv3903c|M.tuberculosis_H37Rv ICDPLTGIKEVWEFLTDQDEDEIQRIAHDIAVVVDQFSGEVDALAAEITA
MMAR_5464|M.marinum_M ICDPLTGIKEVWEVLTGEDEDEIERIAHEIAAVVDHFAAEANALSAQFNA
MAV_2415|M.avium_104 IEALGDIGHDIMLIIDGDAWDEIQKIARDVNAVLQHLGQEARAFEQEIRL
Mvan_1118|M.vanbaalenii_PYR-1 LAVELA-----------------ATVAIGVAASFVSFGAGAVAATAKAAH
MAB_3114|M.abscessus_ATCC_1997 TLGVGLAAIAAIAVITRG-----RATAGGAEIAATAVDACASSLAACIRP
* . . :
Mb3933c|M.bovis_AF2122/97 VVSHAEAVITAMADHAGKQWDRFL---HSNPVGVVIDGTGQQLKGFGEEA
Rv3903c|M.tuberculosis_H37Rv VVSHAEAVITAMADHAGKQWDRFL---HSNPVGVVIDGTGQQLKGFGEEA
MMAR_5464|M.marinum_M ALVHADTVLDTMARHAAREWDQFL---HGNPVGAIVDFAGQRLKGLGEAA
MAV_2415|M.avium_104 LMQAADREIVTCQKYARRGLITFLGEDVGNPVATALDFGINVQEGVVKGA
Mvan_1118|M.vanbaalenii_PYR-1 SVTKFARIIAEAIGAWR---------------------------------
MAB_3114|M.abscessus_ATCC_1997 FLTTLGGITFNAEAVTAAG-------------------------------
:
Mb3933c|M.bovis_AF2122/97 FGMAKDSWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENAPG-VVE
Rv3903c|M.tuberculosis_H37Rv FGMAKDSWDLGPLRASIDPFGWYRSWEEMLTGMAPLAGLGGENAPG-VVE
MMAR_5464|M.marinum_M WGLAETALTYNQIRALLDPLGYARDVGSMAQGMAPLVGLGDDHAPS-VLE
MAV_2415|M.avium_104 VGMGLGLVDLSPHWIALDPEGAGATWGGLVKNAWKESFVNAAVNPQEFAQ
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 SWKQFGKSLIHWDEWTTN-PNEALGKTVFDAATLALP-------------
Rv3903c|M.tuberculosis_H37Rv SWKQFGKSLIHWDEWTTN-PNEALGKTVFDAATLALP-------------
MMAR_5464|M.marinum_M SWKQLGKEVTHWDDWSRS-PGEALGKSEFDLANLFLP-------------
MAV_2415|M.avium_104 ARLQELKGLVHADDWTRDRPGLGAGEVAFDAATLIAPGLGEAGAAADGAS
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 -------------------------GGPLSKLGSKGRDILAGVRGLKERL
Rv3903c|M.tuberculosis_H37Rv -------------------------GGPLSKLGSKGRDILAGVRGLKERL
MMAR_5464|M.marinum_M -------------------------GGPISKAASKGRDLADGLQGLKARL
MAV_2415|M.avium_104 AAARGAEAEADAAGAAGRVGGIAGARGALTDIAKSTADLPKNLEGVTKDL
Mvan_1118|M.vanbaalenii_PYR-1 ----------------------------ISKNISKGVKSAHDIAGVRTKL
MAB_3114|M.abscessus_ATCC_1997 ----------------------------LGAIIGLSIATITGETVVYSNY
: . :
Mb3933c|M.bovis_AF2122/97 EP-----------TTPHLEPPATPPRPGPQPPRIEP--PESGHPAPAPAA
Rv3903c|M.tuberculosis_H37Rv EP-----------TTPHLEPPATPPRPGPQPPRIEP--PESGHPAPAPAA
MMAR_5464|M.marinum_M RPNE-------MGEPNPLKRPDASAAEHTPPSTMPQ--QEAKQPAAAPQP
MAV_2415|M.avium_104 PEIKPPTGGAPVGLGPGGKPIEAPVESAPRPPDGTPGAQRGSPPVATSPA
Mvan_1118|M.vanbaalenii_PYR-1 QRIKN--------LGRKNKPEEKPPAPTPPP-------------------
MAB_3114|M.abscessus_ATCC_1997 KP--------------PGDAFDKTGAKSPGYPG-----------------
. . .
Mb3933c|M.bovis_AF2122/97 KPAPVPANGPLPHSPTESKPPPVDRPA--EPVAPSSASAGQPRVSAATTP
Rv3903c|M.tuberculosis_H37Rv KPAPVPANGPLPHSPTESKPPPVDRPA--EPVAPSSASAGQPRVSAATTP
MMAR_5464|M.marinum_M KPLRPSDGHGLPHSPTESKAPPVDKPATGEPVKPAGAQLGEARAPGAAAR
MAV_2415|M.avium_104 SPGPAGDSGAGPHGPSSSPAPAAPPGGPVGPHDPAPAPAPAASPGGPGGS
Mvan_1118|M.vanbaalenii_PYR-1 ---------------------------------PPGVPAGWTARPADNGM
MAB_3114|M.abscessus_ATCC_1997 -------------------------------DYPAGSLPREFVPPKDGPK
*.
Mb3933c|M.bovis_AF2122/97 G----------------------THVPHGLPQPGEHVPAQAPPATTLLGG
Rv3903c|M.tuberculosis_H37Rv G----------------------THVPHGLPQPGEHVPAQAPPATTLLGG
MMAR_5464|M.marinum_M G----------------------EKELPAQAEHSEQINTPVS-APGPVDG
MAV_2415|M.avium_104 GGVHDPAPAPAPAPAASGGPGDPASVPSGGPHEPASVPAEEPREPVSVPA
Mvan_1118|M.vanbaalenii_PYR-1 G---------------------TVYQQPGSLGNSNSMRIMEPGADPRYPN
MAB_3114|M.abscessus_ATCC_1997 -------------------------WVPNPNPKGNRFGWLDADGNVWVPT
. .
Mb3933c|M.bovis_AF2122/97 P------------PVESAPATAHQPQWATTPAAP-AAAPHSTPGGVHSTE
Rv3903c|M.tuberculosis_H37Rv P------------PVESAPATAHQPQWATTPAAP-AAAPHSTPGGVHSTE
MMAR_5464|M.marinum_M S------------DLDPTPARPHTSRAAPASAMPHLAGSRSTPSDVCGPN
MAV_2415|M.avium_104 GGVHDPVAEPTGGPHEPASVPAAGSRLASVQAAAGDGLPSATPQLFDHTP
Mvan_1118|M.vanbaalenii_PYR-1 G---------------YVKFTNEHNQPINLDGKPGTRADTHIPRNPDGTY
MAB_3114|M.abscessus_ATCC_1997 G----------------KGGLAHGGPHWDVQDPKTGKHENVPPPLPEGEG
*
Mb3933c|M.bovis_AF2122/97 SGPHGRSLSAHGSEPTHDGASHGSGHGSGSEPPGLHAPHREQQLAMHSNE
Rv3903c|M.tuberculosis_H37Rv SGPHGRSLSAHGSEPTHDGASHGSGHGSGSEPPGLHAPHREQQLAMHSNE
MMAR_5464|M.marinum_M VVSEGGSPGGHSTPAALDEVGGAPGASAPGEYHGTGGGPGD-----HGTA
MAV_2415|M.avium_104 SQVPVPAGGSSGEAASVGAHSPSSASSAAPHFESPGGRPSEVPAPNGGAH
Mvan_1118|M.vanbaalenii_PYR-1 PIPKGWP-------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 K-------------------------------------------------
Mb3933c|M.bovis_AF2122/97 PAGEGWHRLSDEAVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPN
Rv3903c|M.tuberculosis_H37Rv PAGEGWHRLSDEAVDPQYGEPLSRHWDFTDNPADRSRINPVVAQLMEDPN
MMAR_5464|M.marinum_M DGGQ-----SLIIVDGLHADDLSALADYTG-------------SGYLDLN
MAV_2415|M.avium_104 GPGESGPAGGHPPGEPPHGGKPSGDGGPPDEDSHRDGTPGNGDDGAAGEI
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 APFGRDPQGQPYTQERYQERFNSVGPWGQQYSNFPPNNGAVP-GTRIAYT
Rv3903c|M.tuberculosis_H37Rv APFGRDPQGQPYTQERYQERFNSVGPWGQQYSNFPPNNGAVP-GTRIAYT
MMAR_5464|M.marinum_M NALRSDILDASLNAR--------VAALNSALQKLPTYDGTVVRGTDLPPE
MAV_2415|M.avium_104 DDGPAGVDGQSTPAKVAGVDYPLPPSDALRVLEHPGAELQRLADGGVPSS
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 NLEKFLSDYGPQLDRIGGDQGKYLAIMEHGR------------PASWEQR
Rv3903c|M.tuberculosis_H37Rv NLEKFLSDYGPQLDRIGGDQGKYLAIMEHGR------------PASWEQR
MMAR_5464|M.marinum_M VVAQYLP----------GEVITEVAFLSTTT------------DPAVAQS
MAV_2415|M.avium_104 ILEGYEPLAGRSVDDFNREFTIETSNGERGWDWEAQAPENGFAGNPIESN
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 ALHVTSLRDPYHAYT-IDWLPEGWFIEVSEVAPGCGQPGGSIQVR-----
Rv3903c|M.tuberculosis_H37Rv ALHVTSLRDPYHAYT-IDWLPEGWFIEVSEVAPGCGQPGGSIQVR-----
MMAR_5464|M.marinum_M PTFAGNVEFRIVSRTGRDVSSVSMFPDEREILFPAGTKFYVIDKT-----
MAV_2415|M.avium_104 HIPAGLHFDRIGPNGGGFLSPEGVPLAERATPPGLAAQYHVFEGTGREIP
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 ---------------------------IFDHQNEMRKVEELIRRGVLRQ-
Rv3903c|M.tuberculosis_H37Rv ---------------------------IFDHQNEMRKVEELIRRGVLRQ-
MMAR_5464|M.marinum_M ---------------------------LDALT--GRTIIDMIER------
MAV_2415|M.avium_104 AGKDWVVQHGPAKEAFGQPGGGDQWIVLDRATNRPVPVDELIRRRLLREI
Mvan_1118|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3114|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3933c|M.bovis_AF2122/97 --------------
Rv3903c|M.tuberculosis_H37Rv --------------
MMAR_5464|M.marinum_M --------------
MAV_2415|M.avium_104 TPPNDKLAIGYRGS
Mvan_1118|M.vanbaalenii_PYR-1 --------------
MAB_3114|M.abscessus_ATCC_1997 --------------