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SSSSTHDALVTAAWREHYPYLVNLAYQMLGDIGDAEDAVQEAFVRLARAEETEIDEPRAWLSVVVGRLCL DQLRSARMRRERTGVASVVESAAPLHVPAVTDPADRVTLDDEVRGALLEVLRSLSPGERVAFVLHDVFAV PFEEIASTVGRPVGTCRQLARRARTRFQQSAARSTDVTGAEHQQLIEKFVTACAQGDLTGLMAVLDPGVW GVGTILGDPAPPPQVNRGRTDVATNLLVYLGPGATLVGGPFGQPVLLAFTQRRLFAVVTLTVREGLVLKI EATADPAARGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2999c | sigI | - | 100% (292) | RNA polymerase sigma factor SigI |
| M. abscessus ATCC 19977 | MAB_3678c | - | 2e-30 | 36.01% (286) | RNA polymerase sigma factor SigJ |
| M. abscessus ATCC 19977 | MAB_1126c | - | 5e-30 | 32.12% (274) | putative sigma factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1221 | sigI | 2e-58 | 46.34% (287) | RNA polymerase sigma factor SigI |
| M. gilvum PYR-GCK | Mflv_4852 | - | 1e-35 | 36.39% (294) | RNA polymerase sigma factor SigJ |
| M. tuberculosis H37Rv | Rv1189 | sigI | 2e-58 | 46.34% (287) | RNA polymerase sigma factor SigI |
| M. leprae Br4923 | MLBr_01076 | sigE | 3e-12 | 30.72% (166) | RNA polymerase sigma factor SigE |
| M. marinum M | MMAR_1196 | sigJ | 1e-32 | 34.98% (283) | alternative RNA polymerase sigma factor SigJ |
| M. avium 104 | MAV_0164 | sigI | 1e-104 | 67.93% (290) | RNA polymerase sigma factor SigI |
| M. smegmatis MC2 155 | MSMEG_1666 | - | 4e-30 | 35.49% (293) | RNA polymerase sigma factor SigJ |
| M. thermoresistible (build 8) | TH_1142 | - | 2e-26 | 30.29% (274) | RNA polymerase sigma factor, sigma-70 family protein |
| M. ulcerans Agy99 | MUL_3630 | - | 2e-32 | 36.08% (291) | alternative RNA polymerase sigma factor SigJ- like |
| M. vanbaalenii PYR-1 | Mvan_1575 | - | 5e-34 | 37.23% (282) | RNA polymerase sigma factor SigJ |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2999c|M.abscessus_ATCC_199 -----MSSSSTHDALVTAAWREHYPYLVNLAYQMLGDIGDAEDAVQEAFV
MAV_0164|M.avium_104 -----MNRSQSADDQVAEAWRRHRPYLVNLAYQMLGDIGDAEDVAQEAFL
Mb1221|M.bovis_AF2122/97 ---------MSQHDPVSAAWRAHRAYLVDLAFRMVGDIGVAEDMVQEAFS
Rv1189|M.tuberculosis_H37Rv ---------MSQHDPVSAAWRAHRAYLVDLAFRMVGDIGVAEDMVQEAFS
Mflv_4852|M.gilvum_PYR-GCK MPHGGIYTRRMTASARVAEFEQMRPHLLSVAYRLTGTVADAEDIVQDAWL
Mvan_1575|M.vanbaalenii_PYR-1 ----------MTTSARVGEFEQLRPHLLSVAYRLTGTLADAEDIVQDAWL
MSMEG_1666|M.smegmatis_MC2_155 ----------MTTAARTDQFEALRPHLLAVAYRLTGTYADAEDIVQEAWI
MMAR_1196|M.marinum_M --------MAVLGAQAASTFESLRPHLMSVAYRLTGTVADAEDIVQEAWL
TH_1142|M.thermoresistible__bu --MTGSGAPSARGDEHAERFTHLRPLLFTIAYEILGSATEADDVLQESYL
MUL_3630|M.ulcerans_Agy99 ----------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWL
MLBr_01076|M.leprae_Br4923 ---MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLL
: . .:*
MAB_2999c|M.abscessus_ATCC_199 RLAR-----AEETEIDEPRAWLSVVVGRLCLDQLRSARMRRERTGVASVV
MAV_0164|M.avium_104 RLSA-----AGD--IDDVRGWLTVVASRLCLDQLRSARARHERPG--DVG
Mb1221|M.bovis_AF2122/97 RLLR-----APVGDIDDERGWLIVVTSRLCLDHIKSASTRRERPQ--DIA
Rv1189|M.tuberculosis_H37Rv RLLR-----APVGDIDDERGWLIVVTSRLCLDHIKSASTRRERPQ--DIA
Mflv_4852|M.gilvum_PYR-GCK RWSTH-----RGAAVEDLKAWLTTVVSRLALDKLRSAAHRRETYVGEWLP
Mvan_1575|M.vanbaalenii_PYR-1 RWEAN-----SATVIEDLKAWLTTVVSRLALDRLRSAAHRRETYVGEWLP
MSMEG_1666|M.smegmatis_MC2_155 RWAG------QEAPIENLQAWLTTVVSRLGLDRLRSAAHRRESYYGEWLP
MMAR_1196|M.marinum_M RWDAAP----GRDDVADLRAWLTTVVSRLGLDKLRSAARRRETYTGHWLP
TH_1142|M.thermoresistible__bu RWAEV-----DLAAVRDTKSYLAKLVSRQALNALRAGARRREDYVGPWLP
MUL_3630|M.ulcerans_Agy99 RLNATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLP
MLBr_01076|M.leprae_Br4923 SPTIMS-----HPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELV
:: . . : : :
MAB_2999c|M.abscessus_ATCC_199 ESAAPLHVPA-VTDPADRVTLDDEVRGALLEVLRSLSPGERVAFVLHDVF
MAV_0164|M.avium_104 EQPAPPRF-----DPADRITLDDEVRTALLEVLRRLSPGERVSFVLHDVF
Mb1221|M.bovis_AF2122/97 AWHDGDASVS-SVDPADRVTLDDEVRLALLIMLERLGPAERVVFVLHEIF
Rv1189|M.tuberculosis_H37Rv AWHDGDASVS-SVDPADRVTLDDEVRLALLIMLERLGPAERVVFVLHEIF
Mflv_4852|M.gilvum_PYR-GCK EPVVTGLD---GRDPLSALVADEDARFAAMVVLENLTPDQRVAFVLHDGF
Mvan_1575|M.vanbaalenii_PYR-1 EPVVTGFD---GVDPLASVVAGEDARFAAMVVLENLTPDQRVAFVLHDGF
MSMEG_1666|M.smegmatis_MC2_155 EPVVTGID---GNDPLNAVVAGEDARFAAMVVLEQLSPDQRVAFVLYDGF
MMAR_1196|M.marinum_M EPVVTGLGDAGGADPLSAVVAAEDARFAVMVVLERLSPDQRVAFVLHDGF
TH_1142|M.thermoresistible__bu EPLLLEER-----DASADVVLAESVSMAMMVVLESLTPDERAVFVLREVF
MUL_3630|M.ulcerans_Agy99 DPIVDGVA---AFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVF
MLBr_01076|M.leprae_Br4923 RQHAARVYWLAYRLSGNQHDAEDLTQETFIRVFRSVQN------YQPGTF
. : . : : :: : *
MAB_2999c|M.abscessus_ATCC_199 AVPFEEIASTVGRPVGTCRQLARRARTRFQQSAARSTDVTGAEHQQLIEK
MAV_0164|M.avium_104 GVPFEAIAQTVGRPVGTCRQLARRARAKFVAAQPKLNTVGAAEHQRVTEK
Mb1221|M.bovis_AF2122/97 GLPYQQIATTIGSQASTCRQLAHRARRKINESR-IAASVEPAQHRVVTRA
Rv1189|M.tuberculosis_H37Rv GLPYQQIATTIGSQASTCRQLAHRARRKINESR-IAASVEPAQHRVVTRA
Mflv_4852|M.gilvum_PYR-GCK AVPFSAIAEVLGTSTQAARQLASRARRAVSSAP---PPAAD--HAEVVGK
Mvan_1575|M.vanbaalenii_PYR-1 AVPFAEIAEVLGSSPESARQLASRARRAASAAP---PPADE--HAEVVGK
MSMEG_1666|M.smegmatis_MC2_155 GVPFPDIADVLGVSAASARQLASRARRAVADAP---PPVDDNTHNEIAGA
MMAR_1196|M.marinum_M AMPFAEVAGVIGASEAAARQLASRARKAVAAAP---PPQPDPTHNEVVGR
TH_1142|M.thermoresistible__bu GFEYGEIATTVGKSVTAVRQIAHRARSHVHARRKRFEPVDPEVSMEITER
MUL_3630|M.ulcerans_Agy99 AVPFDQIAPILERTPEATRKLASRARRRIERAEP-FPDRDLCAQREVVDA
MLBr_01076|M.leprae_Br4923 EGWLHRITTNLFLD-----MVRRRARIRMDALP------------DDYDR
:: : : ***
MAB_2999c|M.abscessus_ATCC_199 FVTACAQGDLTGLMAVLDPGVWGVGTILGDPAPPPQVNRGRTDVATNLLV
MAV_0164|M.avium_104 FITACANGDLAGLAAVLDPTVWGVGTVLADPAPPPQVNHGPDAVATNLLR
Mb1221|M.bovis_AF2122/97 FIEACSNGDLDTLLEVLDPGVAG-----EIDARKGVVVVGADRVGPTILR
Rv1189|M.tuberculosis_H37Rv FIEACSNGDLDTLLEVLDPGVAG-----EIDARKGVVVVGADRVGPTILR
Mflv_4852|M.gilvum_PYR-GCK LLAAMASGDLTAVVSLLHPDVTFTGDSNRRAPTAARVIRGSDKVARFLLG
Mvan_1575|M.vanbaalenii_PYR-1 LLAAMASGDLTEVVAVLHPDVTFTGDSNRRAPTAARVIHGSDKVARFLLG
MSMEG_1666|M.smegmatis_MC2_155 LMAALAAGDMDGVVRLLHPDVTFTGDSNRKAPTAPRVIHGPEKVARFLFG
MMAR_1196|M.marinum_M LMAAMASGDLHSVVSLLHPDVTFTGDANGRAPTAARVICGADKVARFMLG
TH_1142|M.thermoresistible__bu FLTAASTGDMDGLLAMLAPDATWTADGGGKATAARRPIVGAEKVAAVILG
MUL_3630|M.ulcerans_Agy99 FFAAGRSGNFERLVSVLHPDVVLRGDFGPNTPRFR--AQGAATVAKLAR-
MLBr_01076|M.leprae_Br4923 VPADEPNPEQIYHDSRLGPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIG
. : * * . :.
MAB_2999c|M.abscessus_ATCC_199 YLG-------------PGATLVGGP-FGQPVLLAFTQRRLFAVVTLTVRE
MAV_0164|M.avium_104 YLW-------------PDVTLVGGP-AGAPVLLAFSRRRLFAVIVLSIRD
Mb1221|M.bovis_AF2122/97 HWSH------------PATVLVAQPVCGQPAVLAFVNRALAGVLALSIEA
Rv1189|M.tuberculosis_H37Rv HWSH------------PATVLVAQPVCGQPAVLAFVNRALAGVLALSIEA
Mflv_4852|M.gilvum_PYR-GCK LGAKYGPERLLAGSELGLVNGELGVYSPGADATPDAPRIMPRIQALAVRD
Mvan_1575|M.vanbaalenii_PYR-1 LARRYGEQRFFGSGVLGMVNGELGVYTMGAPATEDAPAIAPRIQALTVHR
MSMEG_1666|M.smegmatis_MC2_155 LARRYGPN-WLAGAQLALINGELGTYTPGAPAGDGYPELLPRITAMTVRD
MMAR_1196|M.marinum_M LARRYGPA-FYTANQLALVNGELGSYTLGTAGDGGHWAMLPRITAMTVRD
TH_1142|M.thermoresistible__bu IFR--------AGQRLPDVRIETAIYNCAPAVVVYSRDNLEGVFTVEVVD
MUL_3630|M.ulcerans_Agy99 ---------SYAGPERTVLN---TLVNGAAGAVISISEQASAVMRFLVRN
MLBr_01076|M.leprae_Br4923 ------------------ATLGVKLGTVRSRIHRGRQALRDYLLTAHPRD
. :
MAB_2999c|M.abscessus_ATCC_199 GLVLKIEATADP-------AARGR----
MAV_0164|M.avium_104 ARVVKIEAIADP-------AARSAG---
Mb1221|M.bovis_AF2122/97 GKITKIHVLVQPSTLDPLRAELGGG---
Rv1189|M.tuberculosis_H37Rv GKITKIHVLVQPSTLDPLRAELGGG---
Mflv_4852|M.gilvum_PYR-GCK GLVVAIYDVANPDKFTASPLAR------
Mvan_1575|M.vanbaalenii_PYR-1 GQVVAIYDIANPDKFTASPLR-------
MSMEG_1666|M.smegmatis_MC2_155 GKVCAVWDVANPDKFTGSPLGTAVRRP-
MMAR_1196|M.marinum_M GKVCALWDIANPDKFSGSPLRDLVG---
TH_1142|M.thermoresistible__bu GRITHFYAVRNPEKLAAVDTPRQISR--
MUL_3630|M.ulcerans_Agy99 GRIAAIDVLADPQRIATLDISGLSGPGG
MLBr_01076|M.leprae_Br4923 GATTDATHVKSA----------------
. ..