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SMRADETTRRGATLQLEAVVTQALALVNEGGLEALTMRRLATDLDAHLPTLYRLFGNKDALIDEMAESIL AQASANAQAGRGNWDDKLVDLARSLRSALLGQRDGARIVGGNYAAKRHNLTFVDLLVAHASKSGLAPESA LWAASSVFCFVLGEALEQQGATGEELDAVRGIAHPELYPHLAASPVERLFEFEERFDFGLGLLVGGMRRL LEAVPSPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2380c | - | - | 100% (219) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1430c | - | 2e-22 | 35.03% (197) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0856c | - | 2e-18 | 29.67% (209) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3625 | - | 1e-14 | 31.12% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3679 | - | 3e-06 | 24.18% (182) | putative regulatory protein |
| M. avium 104 | MAV_2588 | - | 5e-07 | 28.66% (157) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3193 | - | 4e-14 | 30.89% (191) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0654 | - | 3e-14 | 29.95% (207) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3622 | - | 7e-06 | 24.18% (182) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2792 | - | 3e-16 | 34.55% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3625|M.gilvum_PYR-GCK --------------------------MQLSKRDVVDVATSLLDDYGIADL
Mvan_2792|M.vanbaalenii_PYR-1 --------------------------MQLHKRDVVDVATSLLDDYGIADL
MSMEG_3193|M.smegmatis_MC2_155 --------------------------MQLHKPDVVAAATKILDDHGIADL
TH_0654|M.thermoresistible__bu --------------------------VQLRKSDVVDAATAILDNYGIADL
MMAR_3679|M.marinum_M --------MFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
MUL_3622|M.ulcerans_Agy99 MISIRTSYVFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
MAB_2380c|M.abscessus_ATCC_199 --------------MSMRADETTRRGATLQLEAVVTQALALVNEGGLEAL
MAV_2588|M.avium_104 --MARTPDKLRRSGYAPAANHGVGRRGLHTRERILGSAAEVFLANGFHAT
: * :. *:
Mflv_3625|M.gilvum_PYR-GCK SMRRLARELNVSAGALYWHFANKQQLLGAVADRILQPLTPA---------
Mvan_2792|M.vanbaalenii_PYR-1 SMRRLARELNVSPGALYWHFANKQQLLGAVADRILAAVDDV---------
MSMEG_3193|M.smegmatis_MC2_155 TMRRLARELDVTPGALYWHFANKQELLGAVADHILRTARTD---------
TH_0654|M.thermoresistible__bu TTRRLARELGVTAGALYWHFANKQELLGAVADRILTPVPAG---------
MMAR_3679|M.marinum_M SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKVP---------
MUL_3622|M.ulcerans_Agy99 SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKVP---------
MAB_2380c|M.abscessus_ATCC_199 TMRRLATDLDAHLPTLYRLFGNKDALIDEMAESILAQASAN---------
MAV_2588|M.avium_104 SLDAIAKTAGASRATVYQYFAGKEEIFRELSALAERDVLAHGEHLGELGP
: :* .. ::* . .: : ::
Mflv_3625|M.gilvum_PYR-GCK ------------------------------------------SGN----W
Mvan_2792|M.vanbaalenii_PYR-1 ------------------------------------------PAG----W
MSMEG_3193|M.smegmatis_MC2_155 ------------------------------------------TADL--AW
TH_0654|M.thermoresistible__bu ------------------------------------------EPEP--GW
MMAR_3679|M.marinum_M ------------------------------------------APTD--DW
MUL_3622|M.ulcerans_Agy99 ------------------------------------------APID--DW
MAB_2380c|M.abscessus_ATCC_199 ------------------------------------------AQAGRGNW
MAV_2588|M.avium_104 TVDGVDALHRWLVAWADIYDAHAAVFAEFPGIGTATGLAVIDASSAAAQF
:
Mflv_3625|M.gilvum_PYR-GCK PERVRATCAQLRDALLSHTDGAELVS------------------------
Mvan_2792|M.vanbaalenii_PYR-1 RDRIAGICAQLRDALLSHTDGAELVS------------------------
MSMEG_3193|M.smegmatis_MC2_155 REQIHESCRALRDALLSHTDGAELVS------------------------
TH_0654|M.thermoresistible__bu AERISSTAGRLRDALLSHTDGAELVS------------------------
MMAR_3679|M.marinum_M RADVHAIATAMWETMRQHPNAIPLVL------------------------
MUL_3622|M.ulcerans_Agy99 RADVHAIATAMWETMRQHPNAIPLVL------------------------
MAB_2380c|M.abscessus_ATCC_199 DDKLVDLARSLRSALLGQRDGARIVG------------------------
MAV_2588|M.avium_104 HQTVTDRLRRTRLRDLEADDAAAALGRIPHMVHLYRYRDMLPLPARATVT
: :. :
Mflv_3625|M.gilvum_PYR-GCK --------------------------ASLAAGQSEVMTAVLARLAAAAGD
Mvan_2792|M.vanbaalenii_PYR-1 --------------------------ASFAAGQSAAMTEVLGHLTAAAAD
MSMEG_3193|M.smegmatis_MC2_155 --------------------------ASFASGQSVVITEIVEQLGRAARA
TH_0654|M.thermoresistible__bu --------------------------ATFAAGQSRVLDEILARFAAAAAA
MMAR_3679|M.marinum_M --------------------------TRRTVSASSYM--VADRLIAALGR
MUL_3622|M.ulcerans_Agy99 --------------------------TRRTVWASSYM--VADRLIAALGR
MAB_2380c|M.abscessus_ATCC_199 --------------------------GNYAAKRHNLT--FVDLLVAHASK
MAV_2588|M.avium_104 WSLTGALQLMLFPETPADVLQVVAPARDGCARTTPRALDYAAATPAAVEA
Mflv_3625|M.gilvum_PYR-GCK AGVASEHTDLVARTVIYYVLG-----------FTADE--------QSRLQ
Mvan_2792|M.vanbaalenii_PYR-1 AGVAPEHAELTARTVIYYVLG-----------FTADE--------QSRLQ
MSMEG_3193|M.smegmatis_MC2_155 AGVSDADVDAAARTVIYYVLG-----------FTVDE--------QSRLQ
TH_0654|M.thermoresistible__bu AGLEGSRAVLAARTIVHYVLG-----------FTGDE--------QSRLQ
MMAR_3679|M.marinum_M SGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGRE--------KEQVA
MUL_3622|M.ulcerans_Agy99 SGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGRE--------KEQVA
MAB_2380c|M.abscessus_ATCC_199 SGLAPESALWAASSVFCFVLG---------EALEQQG--------ATGEE
MAV_2588|M.avium_104 SGSPIPQDVLSVSSALFAERGYYAIGMEEIAAAADVSRATLYRYFSTKDK
:* . *
Mflv_3625|M.gilvum_PYR-GCK WDA-----AGAEVD-TTVWNED----------------------------
Mvan_2792|M.vanbaalenii_PYR-1 WDA-----AGADVA-QTVWAED----------------------------
MSMEG_3193|M.smegmatis_MC2_155 WDA-----VGALGDDQSMLTRD----------------------------
TH_0654|M.thermoresistible__bu WDA-----AGAEVA-EPPADDN----------------------------
MMAR_3679|M.marinum_M VAARIGGLAGAEHPHIAALAQASQRS------------------------
MUL_3622|M.ulcerans_Agy99 VAARIGGLAGAEHPHIAALAQASQRS------------------------
MAB_2380c|M.abscessus_ATCC_199 LDAVRG-IAHPELYPHLAASPVERLF------------------------
MAV_2588|M.avium_104 ILAELTRRAVAEIEKHAAALPAKAADSLTEWMLGYVRFHRTYRGVIRAWF
* . .
Mflv_3625|M.gilvum_PYR-GCK --------PNARFAFGLRLLTDGIAAHSRTGS------------------
Mvan_2792|M.vanbaalenii_PYR-1 --------PSARFTFGLHLLVDGIAVHSRAGT------------------
MSMEG_3193|M.smegmatis_MC2_155 --------GTRQFRFGLQLLVDGLAAHGGGSEFTGFSSAERSFE------
TH_0654|M.thermoresistible__bu --------PSARFAFGLNLLINGIAAEIDAAARKSE--------------
MMAR_3679|M.marinum_M -------TPAADFERALDILLAGIESFERRRDRR----------------
MUL_3622|M.ulcerans_Agy99 -------TPAADFERALDILLAGIESFERRRDRR----------------
MAB_2380c|M.abscessus_ATCC_199 -------EFEERFDFGLGLLVGGMRRLLEAVPSPG---------------
MAV_2588|M.avium_104 DGAVAEQLSNADVDHGIGAIFQAVAALLSTVDLPPGIDADVAGAVFVAVL
. .: : .:
Mflv_3625|M.gilvum_PYR-GCK ----------------------------------
Mvan_2792|M.vanbaalenii_PYR-1 ----------------------------------
MSMEG_3193|M.smegmatis_MC2_155 ----------------------------------
TH_0654|M.thermoresistible__bu ----------------------------------
MMAR_3679|M.marinum_M ----------------------------------
MUL_3622|M.ulcerans_Agy99 ----------------------------------
MAB_2380c|M.abscessus_ATCC_199 ----------------------------------
MAV_2588|M.avium_104 GRMSEPTGASGPNSDEQAAELMVKLLRRSLLREA