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TRTDGDQWDIVSSVGFTALMVSSFRALETTRTEPLIRDEYARAFVEASGEPRLTEALAAGTPESEWDTAT VYLVNHLAVRTKYFDEFFAAATGSGIQQVVILAAGLDSRVYRLPWPDGTVVYELDQPKVLEFKDHVLREE HAVPLAERREVAVDLRDDWIAALRTAGFDATKPTAWLAEGLLAYLPGAAQDALFENITAHSAPGSFLATE WRRRQATAGQWQDAVNKLKPEFIKDISIGSLIYDDERQDPIEWLREHGWQVDTANRLEQAAAYGRPAPSE HSDVTSLWSDAYFITATR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0027c | - | - | 100% (299) | hypothetical protein MAB_0027c |
| M. abscessus ATCC 19977 | MAB_4584c | - | 9e-80 | 51.68% (298) | hypothetical protein MAB_4584c |
| M. abscessus ATCC 19977 | MAB_4586c | - | 4e-73 | 51.43% (280) | hypothetical protein MAB_4586c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0150 | - | 2e-69 | 49.31% (290) | hypothetical protein Mb0150 |
| M. gilvum PYR-GCK | Mflv_5025 | - | 2e-69 | 49.01% (304) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv0145 | - | 2e-69 | 49.31% (290) | hypothetical protein Rv0145 |
| M. leprae Br4923 | MLBr_02020 | - | 2e-62 | 45.25% (305) | hypothetical protein MLBr_02020 |
| M. marinum M | MMAR_5323 | - | 1e-67 | 46.23% (305) | O-methyltransferase |
| M. avium 104 | MAV_4444 | - | 4e-67 | 46.65% (313) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_1481 | - | 7e-70 | 50.00% (312) | methyltransferase |
| M. thermoresistible (build 8) | TH_2759 | - | 3e-76 | 52.56% (293) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_4402 | - | 5e-68 | 46.23% (305) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1345 | - | 1e-66 | 45.45% (308) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5025|M.gilvum_PYR-GCK ------------MARTPDDSWDLASSVGATATMVAAGRAVAS----ADPD
MAV_4444|M.avium_104 ------------MTRTHDDEWDLASSVGATATMVAAGRAMAT----KDPR
MSMEG_1481|M.smegmatis_MC2_155 ------------MARTDTDSWDLASSVGATATMVAAARAIAS----TEPN
Mvan_1345|M.vanbaalenii_PYR-1 ------------MARTEGDTWDLGSSVGATATSVAANRAFASRSTAGGPE
MMAR_5323|M.marinum_M ------------MPRTDNDSWTITESVGATALGVAAARAAET----ESEN
MUL_4402|M.ulcerans_Agy99 ------------MPRTDNDSWTITESVGATALGVAAARAAET----ESEN
MAB_0027c|M.abscessus_ATCC_199 ------------MTRTDGDQWDIVSSVGFTALMVSSFRALET----TRTE
Mb0150|M.bovis_AF2122/97 MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVET----AATN
Rv0145|M.tuberculosis_H37Rv MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVET----AATN
TH_2759|M.thermoresistible__bu MVMMFDVTEAASAR-SEGDSWDITESVGATALGVAAERALET----SQPD
MLBr_02020|M.leprae_Br4923 ---MMAATPEFGSLRSDDDHWDIVSSVGYTALLVAGWRALHA----VGPQ
: * * : .*** ** *:. ** :
Mflv_5025|M.gilvum_PYR-GCK PLINDPYAEPLVRAVGLDFFTRMLDGELDLSVFPDSSPE--RAQAMIDGM
MAV_4444|M.avium_104 GLIDDPFAEPLVRAVGVDFFTKMMDGELDLDAIENATPV--RIQSMVDGM
MSMEG_1481|M.smegmatis_MC2_155 ALIDDPYAADLVRKVGLEFFTKLVDGDIALD---GDDAA--AAGLMVSMM
Mvan_1345|M.vanbaalenii_PYR-1 PLLNDPYADLLVEAVGLPHFIRVARGEIDFD---DDPLF--GARQMLEQI
MMAR_5323|M.marinum_M PLIEDPFARVFVDAAGDGMWSMFANPALLAGAPEIESQVGARVRQMIDFM
MUL_4402|M.ulcerans_Agy99 PLIEDPFARVFVDAAGDGMWSMFANPALLAGAPEIESQVGARVRQMIDFM
MAB_0027c|M.abscessus_ATCC_199 PLIRDEYARAFVEASGEPRLTEALAAGTPESEWDTATVY------LVNHL
Mb0150|M.bovis_AF2122/97 PLIRDEFAKVLVSSAG-TAWARLADADLAWLDGDQLGRR--VHRVACDYQ
Rv0145|M.tuberculosis_H37Rv PLIRDEFAKVLVSSAG-TAWARLADADLAWLDGDQLGRR--VHRVACDYQ
TH_2759|M.thermoresistible__bu PLIRDEYAFLLVSAAG-PPWTQLASSDLSWLGDDETARR--MHLMSRDYQ
MLBr_02020|M.leprae_Br4923 PLVRDEYAKYFITASRDPYLMNLLAN-------PGTSLN---ETAFPRLY
*: * :* ::
Mflv_5025|M.gilvum_PYR-GCK AVRTRFFDDCCLAAASAG---VRQVVILAAGLDARTYRLPWPDGTVVYEL
MAV_4444|M.avium_104 AVRTKYFDDYFVDATDAG---VRQVVILASGLDSRAYRLPWPAGTVVYEI
MSMEG_1481|M.smegmatis_MC2_155 AVRTRFFDDFFCDAAGAG---IRQSVILAAGLDSRAYRLGWPAGTVVYEI
Mvan_1345|M.vanbaalenii_PYR-1 TVRTRHFDDFFAGAMAAGPPKIRQAVILASGLDTRAYRLPWPAGTVVYEI
MMAR_5323|M.marinum_M ATRTAFFDEFFLGAADTG---VRQVVILASGLDSRAWRLPWPDGTVVYEL
MUL_4402|M.ulcerans_Agy99 ATRTAFFDEFFLGAADAG---VRQVVILASGLDSRAWRLPWPDGTVVYEL
MAB_0027c|M.abscessus_ATCC_199 AVRTKYFDEFFAAATGSG---IQQVVILAAGLDSRVYRLPWPDGTVVYEL
Mb0150|M.bovis_AF2122/97 AVRTHFFDEYFGAAVDAG---VRQVVILAAGLDARAYRLNWPAGTVVYEI
Rv0145|M.tuberculosis_H37Rv AVRTHFFDEYFGAAVDAG---VRQVVILAAGLDARAYRLNWPAGTVVYEI
TH_2759|M.thermoresistible__bu AVRTHYFDRYFAAAARAG---IRQIVLLAAGLDSRAYRLDWPAGTVVYEL
MLBr_02020|M.leprae_Br4923 GVQTRFFDDFFSSAGDTG---IRQAVIVAAGLDSRAYRLKWPNGATVFEI
.:* .** * :* ::* *::*:***:*.:** ** *:.*:*:
Mflv_5025|M.gilvum_PYR-GCK DQPDVIAFKTQTLRNLGAEPAATQRPVPVDLREDWPAALRAAGFDATRPT
MAV_4444|M.avium_104 DQPRVIEFKSNTLAEVGAEPTATRRTIPIDLRGDWPAALSAAGFDPAAPT
MSMEG_1481|M.smegmatis_MC2_155 DQPRVIEAKTAAMAEIGASPTAERRTVAVDLRDDWPAALRAAGFDAATPT
Mvan_1345|M.vanbaalenii_PYR-1 DQPTVIEFKTAVLADAGVAPTAERRTVGIDLREDWPAALRGAGFDPTRPT
MMAR_5323|M.marinum_M DQPRVLEFKSATLRQHGARPTAQLVNIPIDLRQDWPAALLDSGFDASKPT
MUL_4402|M.ulcerans_Agy99 DQPRVLEFKSATLRQHGARPTAQLMNIPIDLRQDWPAALLDSGFDASKPT
MAB_0027c|M.abscessus_ATCC_199 DQPKVLEFKDHVLREEHAVPLAERREVAVDLRDDWIAALRTAGFDATKPT
Mb0150|M.bovis_AF2122/97 DQPSVLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPT
Rv0145|M.tuberculosis_H37Rv DQPSVLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPT
TH_2759|M.thermoresistible__bu DQPRVLDFKNRTLQAHGAVAKADRRTVAVDLRDDWPAALRHAGFDSAAPT
MLBr_02020|M.leprae_Br4923 DLPKVLEFKARVLAEQGAIPNAGRSEVAADLRADWPRALKAAGFDPQRSS
* * *: * : . . * : *** ** ** :*** .:
Mflv_5025|M.gilvum_PYR-GCK AWLAEGLLIYLPPEAQDALFDTVTALSAPGSTLATEYVPGIV---DFDGA
MAV_4444|M.avium_104 AWLAEGLLIYLPPEAQDRLFDNITALSAPGSTIATEFVPGIV---DFDAE
MSMEG_1481|M.smegmatis_MC2_155 AWIAEGLLVYLPPEAQDRLFDNITALSARGSRLATEYHPDIT---STLRG
Mvan_1345|M.vanbaalenii_PYR-1 AWIAEGLLIYLPPDAQDRLLDHITALSAPGSRLATE-HMDAK---ALTGE
MMAR_5323|M.marinum_M AWSAEGLVRYLPARAQDLLFERIDTLSPAGSWLATNVPQEGFSDPDLVRR
MUL_4402|M.ulcerans_Agy99 AWSAEGLVRYLPARAQDLLFERIDTLSPAGSWLATNVPQGGFLDPDLVRR
MAB_0027c|M.abscessus_ATCC_199 AWLAEGLLAYLPGAAQDALFENITAHSAPGSFLATEWRRRQA----TAGQ
Mb0150|M.bovis_AF2122/97 AWLAEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNT--KGNTQR
Rv0145|M.tuberculosis_H37Rv AWLAEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNT--KGNTQR
TH_2759|M.thermoresistible__bu AWLAEGLLCYLPADAQDRLFERITALSAPGSWLAVEAFHHDP--QRATER
MLBr_02020|M.leprae_Br4923 AWSVEGLLPYLTNDAQSALFTRIGELCAPGSRIAVGALGSRL-----DRK
** .***: **. * . *: : .. ** :*.
Mflv_5025|M.gilvum_PYR-GCK KARALSEPLREHG--LDIDMP---SLVYTG-ARTPVMDHLRGAGWQVSGT
MAV_4444|M.avium_104 RVREMSGSFREHG--VDIDMA---SLVYAG-ERNHVIDYLNGLGWRAEGV
MSMEG_1481|M.smegmatis_MC2_155 RGQAMSERWRDHG--FDVDLS---DLWYGG-DRNAADEYLAGHGWQVSTR
Mvan_1345|M.vanbaalenii_PYR-1 WARAMTERARRHG--SDVNLS---ELFYSG-PRTSATEHLRAQGWQTEVL
MMAR_5323|M.marinum_M QHEEMQRMRAAAGRLVEIQMPAVEDLWYAE-ERTPVADWLGEHGWRASAT
MUL_4402|M.ulcerans_Agy99 QHEEMQRMRAAAGRLVEIQMPAVEDLWYAE-ERTPVADWLGEHGWRASAT
MAB_0027c|M.abscessus_ATCC_199 WQDAVNKLKPEFI--KDISIG---SLIYDD-ERQDPIEWLREHGWQVDTA
Mb0150|M.bovis_AF2122/97 ----WN----RMRERLGLDID-VQALTYHEPDRSDAAQWLATHGWQVHSV
Rv0145|M.tuberculosis_H37Rv ----WN----RMRERLGLDID-VQALTYHEPDRSDAAQWLATHGWQVHSV
TH_2759|M.thermoresistible__bu RRAEWRDRTARMKAALDLNLD-FEALTYDDPDRADAGEWLAAHGWHPDSV
MLBr_02020|M.leprae_Br4923 QLAALEATHPGVNISGDVDFS---ALTYEP--KTDSAQWLAAHGWAVEPV
:.: * * : : * **
Mflv_5025|M.gilvum_PYR-GCK -ARAELFARFGRPLPQDADGTDPLGEIVYVSATLAADA--
MAV_4444|M.avium_104 -TRTELFHRHGIEVPAPEH-DDPLGEIIFISATRTG----
MSMEG_1481|M.smegmatis_MC2_155 -PRPEVFAAYGRTFPDLTLTGDDNAAMR-QSVAITATRS-
Mvan_1345|M.vanbaalenii_PYR-1 -SSNDAYQAQG-----FAPVADHLVAMIGDSGYLTARLD-
MMAR_5323|M.marinum_M -TSAELLTRYGRPVP--DDAEGPVPPTLFVSAHRPAA---
MUL_4402|M.ulcerans_Agy99 -TSAELLTRYGRPVP--DDAEGPVPPTLFVSAHRPAA---
MAB_0027c|M.abscessus_ATCC_199 -NRLEQAAAYGRPAP---SEHSDVTSLWSDAYFITATR--
Mb0150|M.bovis_AF2122/97 -SNREEMARLGRAIP-QDLVDETVRTTLLRGRLVTPAQPA
Rv0145|M.tuberculosis_H37Rv -SNREEMARLGRAIP-QDLVDETVRTTLLRGRLVTPAQPA
TH_2759|M.thermoresistible__bu -PGTEEMARMGRPVP-ADLLDVAVPSTLLRAHLNGASR--
MLBr_02020|M.leprae_Br4923 RNTLELQTSYGMTPP----DVDVQMDSFMHSQYITATR--
: * .