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MARTEDDSWEITESVGATALGVASARAAETRSQHPLISDPFAQVFLDAVGDGVWNWHSAPQLPAELLEIE PDLPLQMEAMVSYMASRTAFFDEFFLDATRAGIGQAVILAAGLDSRAWRLPWPAGTTVFELDQPRVLEFK AATLAEHGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVPSVWSAEGLMPYLPAVAQDLLFERVQGLTVR ASRIAVEALGPKFLDPQVRANRSARMERIRAVMAHVEPQREIPRTDELWYFEEREDVGDWFRRHDWDVTV TPSGELMAGYGRAAAAQVEDRVPTNLFVAAQRK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0955 | - | - | 100% (313) | hypothetical protein MMAR_0955 |
| M. marinum M | MMAR_5323 | - | 2e-94 | 54.49% (312) | O-methyltransferase |
| M. marinum M | MMAR_1595 | - | 5e-74 | 47.76% (312) | O-methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3793c | - | 1e-98 | 56.45% (310) | hypothetical protein Mb3793c |
| M. gilvum PYR-GCK | Mflv_0743 | - | 2e-67 | 46.53% (288) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv3767c | - | 1e-98 | 56.45% (310) | hypothetical protein Rv3767c |
| M. leprae Br4923 | MLBr_02640 | - | 3e-65 | 44.41% (313) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3886c | - | 2e-87 | 53.67% (313) | hypothetical protein MAB_3886c |
| M. avium 104 | MAV_4557 | - | 1e-150 | 81.09% (312) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_0093 | - | 9e-68 | 49.49% (295) | methyltransferase |
| M. thermoresistible (build 8) | TH_4502 | - | 2e-66 | 46.78% (295) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_0706 | - | 1e-180 | 99.36% (312) | hypothetical protein MUL_0706 |
| M. vanbaalenii PYR-1 | Mvan_0104 | - | 3e-70 | 45.22% (314) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3793c|M.bovis_AF2122/97 --------MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFA
Rv3767c|M.tuberculosis_H37Rv --------MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFA
MMAR_0955|M.marinum_M --------MARTEDDSWEITESVGATALGVASARAAETRSQHPLISDPFA
MUL_0706|M.ulcerans_Agy99 --------MARTEDDSWEITESVGATALGVASARAAETRSQHPLISDPFA
MAV_4557|M.avium_104 ------MSTARTDDDSWEITESVGATALGVASARAAETRSENPLIKDPFA
MAB_3886c|M.abscessus_ATCC_199 --------MARRDGDSWEITESVGTTALGVASARDAETRSPNPLISDPYA
Mflv_0743|M.gilvum_PYR-GCK ------MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALINDPYA
Mvan_0104|M.vanbaalenii_PYR-1 ------MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDDPYA
TH_4502|M.thermoresistible__bu ------MSSLRTDDDTWDIATSVGSTAVMVAASRAAETEREDALIRDPYA
MLBr_02640|M.leprae_Br4923 ---------MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYA
MSMEG_0093|M.smegmatis_MC2_155 MTDVRETPSVRSARDSWGITESVGATALGVAAARAAETAQADPLIRDEFA
* *:* * ***:**: **::* *** ..** * :*
Mb3793c|M.bovis_AF2122/97 RIFVDAAGDGIWSMYTNR-TLLAGATDLDPDLRAPIQQMIDFMAARTAFF
Rv3767c|M.tuberculosis_H37Rv RIFVDAAGDGIWSMYTNR-TLLAGATDLDPDLRAPIQQMIDFMAARTAFF
MMAR_0955|M.marinum_M QVFLDAVGDGVWNWHSAP-QLPAELLEIEPDLPLQMEAMVSYMASRTAFF
MUL_0706|M.ulcerans_Agy99 QVFLDAVGDGVWNWHSAP-QLPAELLEIEPDLPLQMEAMVSYMASRTAFF
MAV_4557|M.avium_104 QVFLDAAGDGVWNWHSAP-QLPPELIEAEPTIPLQQQAMVSYMASRTAFF
MAB_3886c|M.abscessus_ATCC_199 GHFLAAAGDGAWNAYRFDGEPPAALVEAEPRLVERIDAMRSYVACRTKFF
Mflv_0743|M.gilvum_PYR-GCK KVLVEGAGAG-AWRFIADEDLVAKASESDTEVGALFEHMKNYQAVRTHFF
Mvan_0104|M.vanbaalenii_PYR-1 KILVAGAGNG-AWQYIADDGFVAKVTESDPEIGPLFEHMKNYQAVRTHFF
TH_4502|M.thermoresistible__bu KVLVAGAGTG-VWELILDDDFTAKIEAADPETAAIFDHMGNYQAVRTHFF
MLBr_02640|M.leprae_Br4923 KLLVTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFF
MSMEG_0093|M.smegmatis_MC2_155 FLLVSAAGPTWAQMAVSDPHWLG----ADADARRIHEISRNYQAVRTHYF
:: .* :. : .: * ** :*
Mb3793c|M.bovis_AF2122/97 DEYFLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKS
Rv3767c|M.tuberculosis_H37Rv DEYFLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKS
MMAR_0955|M.marinum_M DEFFLDATRAGIGQAVILAAGLDSRAWRLPWPAGTTVFELDQPRVLEFKA
MUL_0706|M.ulcerans_Agy99 DEFFLDATRAGIGQAVILAAGLDSRAWRLPWPAGTTVFELDQPRVLEFKA
MAV_4557|M.avium_104 DSFFLEATGAGIRQAVILAAGLDARSWRLPWPAGTTVYELDQPRVLEFKE
MAB_3886c|M.abscessus_ATCC_199 DDFFGDASTSGIRQAVILASGLDARAWRLDWPRDAVLFELDLPRVLAFKA
Mflv_0743|M.gilvum_PYR-GCK DAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLDYKS
Mvan_0104|M.vanbaalenii_PYR-1 DAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLAYKS
TH_4502|M.thermoresistible__bu DTYFARAAEAGIRQVVILASGLDSRAYRLPWPDGTVVYEIDQPKVLEYKS
MLBr_02640|M.leprae_Br4923 DTYFNNAVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKS
MSMEG_0093|M.smegmatis_MC2_155 DEYFSDVAHAGIRQVVILAAGLDSRAFRLDWPAGTTVFEIDQPKVLEYKT
* :* . *: * ****:***:*::** ** .:.::*:* * ** :*
Mb3793c|M.bovis_AF2122/97 ATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRY
Rv3767c|M.tuberculosis_H37Rv ATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRY
MMAR_0955|M.marinum_M ATLAEHGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVPSVWSAEGLMPY
MUL_0706|M.ulcerans_Agy99 ATLAEHGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVSSVWSAEGLMPY
MAV_4557|M.avium_104 STLAEHGAQPACNRVAVPVDLRHDWPEALRQAGFDASAPSVWSAEGLMPY
MAB_3886c|M.abscessus_ATCC_199 ETLDKQGATPRIRHVPVAVDLRDDWPAALRAGGFDVGRPAAWIAEGLLPY
Mflv_0743|M.gilvum_PYR-GCK STLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGLLMY
Mvan_0104|M.vanbaalenii_PYR-1 STLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGLLMY
TH_4502|M.thermoresistible__bu ATLAAHGVQPAADRREVAVDLRHDWPKALRAKGFDPQQRTAWLAEGLLMY
MLBr_02640|M.leprae_Br4923 TTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGLLMY
MSMEG_0093|M.smegmatis_MC2_155 ATLDAHGAVAKARYVPVPADLRDDWPAALVEAGFDPAQPTAWLAEGLLPY
** :*. . *. ***.*** ** *** .* ****: *
Mb3793c|M.bovis_AF2122/97 LPARAQDLLFERIDALSRPGSWLASNVPGAGFLD--PERMRRQRADMRRM
Rv3767c|M.tuberculosis_H37Rv LPARAQDLLFERIDALSRPGSWLASNVPGAGFLD--PERMRRQRADMRRM
MMAR_0955|M.marinum_M LPAVAQDLLFERVQGLTVRASRIAVEALGPKFLD--PQVRANRSARMERI
MUL_0706|M.ulcerans_Agy99 LPAVAQDLLFERVQGLTVRASRIAVEALGPKFLD--PQVRANRSARIERI
MAV_4557|M.avium_104 LPAAAQDLLFDRIQGLTVAGSRVAVEALGPKFLD--PQARAKRRERMDRI
MAB_3886c|M.abscessus_ATCC_199 LPPAAQDLLFERIDTLSAPGSRIAVENFGEDFFN--PETLARQRERGQAF
Mflv_0743|M.gilvum_PYR-GCK LPADAQDRLFAQITELSAPGSQVAAESMGVHAP----DRRERMRERFASI
Mvan_0104|M.vanbaalenii_PYR-1 LPADAQDRLFAQITELSAPGSRVAAESMGIHAQ----DRRERMRERFASI
TH_4502|M.thermoresistible__bu LPADAQDRLFENITALSAPGSRLAVETAAEEPV----DRREQMRARMERI
MLBr_02640|M.leprae_Br4923 LPATAQDGLFTEIGGLSAVGSRIAVETSPLHGD----EWREQMQLRFRRV
MSMEG_0093|M.smegmatis_MC2_155 LPADAQDRLFELVGVNSAPGSRIAVEAFNMSPERYTEERRAQRRARGEQM
**. *** ** : : .* :* : : . .
Mb3793c|M.bovis_AF2122/97 RAAAAKLVET-EISDVDDLWYAE-QRTAVAEWLRERGWDVSTATLPELLA
Rv3767c|M.tuberculosis_H37Rv RAAAAKLVET-EISDVDDLWYAE-QRTAVAEWLRERGWDVSTATLPELLA
MMAR_0955|M.marinum_M RAVMAHVEPQREIPRTDELWYFE-EREDVGDWFRRHDWDVTVTPSGELMA
MUL_0706|M.ulcerans_Agy99 RAVMAHVEPQREIPRTDELWYFE-EREDVGDWFRRHDWDVTVTPSGELMA
MAV_4557|M.avium_104 QALMARIDPDRAVPRTDELWYFE-EREDVGEWFGRHGWDVRVTPSDELMA
MAB_3886c|M.abscessus_ATCC_199 RRVAEEMQGQ-DIPDVADLWYLE-ERTDAGEFLAGRGWRVTSETAVALLG
Mflv_0743|M.gilvum_PYR-GCK ASQIDIEP-M----DITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMR
Mvan_0104|M.vanbaalenii_PYR-1 TAQFDVEP-M----DITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMR
TH_4502|M.thermoresistible__bu ASQFGLEKAL----DVAQLMYDDPDRADVPEWLTGHGWRTEWVSAPDEMR
MLBr_02640|M.leprae_Br4923 SDALGFEQAV----DVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMR
MSMEG_0093|M.smegmatis_MC2_155 RKQLDLDI------DVDALMYTADDRADAAQWLSEHGWQVEAVPSADEMA
* * :* . ::: :.* . . :
Mb3793c|M.bovis_AF2122/97 RYGRSIP-----------HSGE-DSIPPNLFVSAQRATS
Rv3767c|M.tuberculosis_H37Rv RYGRSIP-----------HSGE-DSIPPNLFVSAQRATS
MMAR_0955|M.marinum_M GYGRAAA-----------AQVE-DRVPTNLFVAAQRK--
MUL_0706|M.ulcerans_Agy99 GYGRAAA-----------AQVE-DRVPTNLFVAAQRN--
MAV_4557|M.avium_104 GYGRPAP-----------AEVR-DFVPGNLFVAAQRR--
MAB_3886c|M.abscessus_ATCC_199 RHGRDIP-----------ADLP-DATPNSAFLFAQKAD-
Mflv_0743|M.gilvum_PYR-GCK RLDRYV----------EVADS--DGQSFSTFTTGTKL--
Mvan_0104|M.vanbaalenii_PYR-1 RLHRLV----------EIADG--DDQSFSTFTTAVKR--
TH_4502|M.thermoresistible__bu RLDRFVAAAMPPGDDADAADL--DDTAFSKFVTAERPS-
MLBr_02640|M.leprae_Br4923 RVGRWG-------DGVPMAD---DKDAFAEFVTAHRL--
MSMEG_0093|M.smegmatis_MC2_155 RLGRPA-------AEADLAEFGMDGVLMRARLDGERL--
* . * . :