For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
STARTDDDSWEITESVGATALGVASARAAETRSENPLIKDPFAQVFLDAAGDGVWNWHSAPQLPPELIEA EPTIPLQQQAMVSYMASRTAFFDSFFLEATGAGIRQAVILAAGLDARSWRLPWPAGTTVYELDQPRVLEF KESTLAEHGAQPACNRVAVPVDLRHDWPEALRQAGFDASAPSVWSAEGLMPYLPAAAQDLLFDRIQGLTV AGSRVAVEALGPKFLDPQARAKRRERMDRIQALMARIDPDRAVPRTDELWYFEEREDVGEWFGRHGWDVR VTPSDELMAGYGRPAPAEVRDFVPGNLFVAAQRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4557 | - | - | 100% (315) | methyltransferase, putative, family protein |
| M. avium 104 | MAV_4558 | - | e-130 | 70.32% (310) | methyltransferase, putative, family protein |
| M. avium 104 | MAV_0301 | - | e-103 | 59.16% (311) | methyltransferase, putative, family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3793c | - | 2e-98 | 55.81% (310) | hypothetical protein Mb3793c |
| M. gilvum PYR-GCK | Mflv_0743 | - | 2e-72 | 47.93% (290) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv3767c | - | 2e-98 | 55.81% (310) | hypothetical protein Rv3767c |
| M. leprae Br4923 | MLBr_02640 | - | 3e-66 | 46.44% (295) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3886c | - | 1e-88 | 53.53% (312) | hypothetical protein MAB_3886c |
| M. marinum M | MMAR_0955 | - | 1e-150 | 81.09% (312) | hypothetical protein MMAR_0955 |
| M. smegmatis MC2 155 | MSMEG_0095 | - | 2e-71 | 48.23% (282) | methyltransferase |
| M. thermoresistible (build 8) | TH_4502 | - | 2e-71 | 48.44% (289) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_0706 | - | 1e-149 | 80.71% (311) | hypothetical protein MUL_0706 |
| M. vanbaalenii PYR-1 | Mvan_0104 | - | 9e-75 | 49.66% (290) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0095|M.smegmatis_MC2_155 MSSLRTDDDTWDIATSVGSTAVMVAAARAGETERDDALIRDPYAKILVAG
TH_4502|M.thermoresistible__bu MSSLRTDDDTWDIATSVGSTAVMVAASRAAETEREDALIRDPYAKVLVAG
Mflv_0743|M.gilvum_PYR-GCK MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALINDPYAKVLVEG
Mvan_0104|M.vanbaalenii_PYR-1 MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDDPYAKILVAG
MLBr_02640|M.leprae_Br4923 ---MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTN
MMAR_0955|M.marinum_M --MARTEDDSWEITESVGATALGVASARAAETRSQHPLISDPFAQVFLDA
MUL_0706|M.ulcerans_Agy99 --MARTEDDSWEITESVGATALGVASARAAETRSQHPLISDPFAQVFLDA
MAV_4557|M.avium_104 MSTARTDDDSWEITESVGATALGVASARAAETRSENPLIKDPFAQVFLDA
MAB_3886c|M.abscessus_ATCC_199 --MARRDGDSWEITESVGTTALGVASARDAETRSPNPLISDPYAGHFLAA
Mb3793c|M.bovis_AF2122/97 --MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDA
Rv3767c|M.tuberculosis_H37Rv --MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDA
* ..*:* * ***:**: **::* .** ..** **:* ::
MSMEG_0095|M.smegmatis_MC2_155 AGTG-VWETVLDS-EFAAKIENLDPEAAAIFAHMGNYQAVRTHFFDAYYR
TH_4502|M.thermoresistible__bu AGTG-VWELILDD-DFTAKIEAADPETAAIFDHMGNYQAVRTHFFDTYFA
Mflv_0743|M.gilvum_PYR-GCK AGAG-AWRFIADE-DLVAKASESDTEVGALFEHMKNYQAVRTHFFDAFFS
Mvan_0104|M.vanbaalenii_PYR-1 AGNG-AWQYIADD-GFVAKVTESDPEIGPLFEHMKNYQAVRTHFFDAFFA
MLBr_02640|M.leprae_Br4923 TGAGALWEAMLDP-SMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFN
MMAR_0955|M.marinum_M VGDG-VWNWHSAP-QLPAELLEIEPDLPLQMEAMVSYMASRTAFFDEFFL
MUL_0706|M.ulcerans_Agy99 VGDG-VWNWHSAP-QLPAELLEIEPDLPLQMEAMVSYMASRTAFFDEFFL
MAV_4557|M.avium_104 AGDG-VWNWHSAP-QLPPELIEAEPTIPLQQQAMVSYMASRTAFFDSFFL
MAB_3886c|M.abscessus_ATCC_199 AGDG-AWNAYRFDGEPPAALVEAEPRLVERIDAMRSYVACRTKFFDDFFG
Mb3793c|M.bovis_AF2122/97 AGDG-IWSMYTNR-TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFL
Rv3767c|M.tuberculosis_H37Rv AGDG-IWSMYTNR-TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFL
.* * * . :. * .: * ** *** ::
MSMEG_0095|M.smegmatis_MC2_155 EAADAGIRQIVILASGLDSRAYRLDWPAGTTVYEIDQPKVLEYKSATLRE
TH_4502|M.thermoresistible__bu RAAEAGIRQVVILASGLDSRAYRLPWPDGTVVYEIDQPKVLEYKSATLAA
Mflv_0743|M.gilvum_PYR-GCK AAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLDYKSSTLAA
Mvan_0104|M.vanbaalenii_PYR-1 AAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLAYKSSTLAS
MLBr_02640|M.leprae_Br4923 NAVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAE
MMAR_0955|M.marinum_M DATRAGIGQAVILAAGLDSRAWRLPWPAGTTVFELDQPRVLEFKAATLAE
MUL_0706|M.ulcerans_Agy99 DATRAGIGQAVILAAGLDSRAWRLPWPAGTTVFELDQPRVLEFKAATLAE
MAV_4557|M.avium_104 EATGAGIRQAVILAAGLDARSWRLPWPAGTTVYELDQPRVLEFKESTLAE
MAB_3886c|M.abscessus_ATCC_199 DASTSGIRQAVILASGLDARAWRLDWPRDAVLFELDLPRVLAFKAETLDK
Mb3793c|M.bovis_AF2122/97 ATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKSATLRQ
Rv3767c|M.tuberculosis_H37Rv ATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKSATLRQ
: *: * ****:***:*::** ** .:.::*:* * ** :* **
MSMEG_0095|M.smegmatis_MC2_155 HGIEPVAQRREVPVDLRFDWPTALHDAGFDASLPTAWLAEGLLMYLPAEA
TH_4502|M.thermoresistible__bu HGVQPAADRREVAVDLRHDWPKALRAKGFDPQQRTAWLAEGLLMYLPADA
Mflv_0743|M.gilvum_PYR-GCK HGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGLLMYLPADA
Mvan_0104|M.vanbaalenii_PYR-1 HGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGLLMYLPADA
MLBr_02640|M.leprae_Br4923 HGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATA
MMAR_0955|M.marinum_M HGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVPSVWSAEGLMPYLPAVA
MUL_0706|M.ulcerans_Agy99 HGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVSSVWSAEGLMPYLPAVA
MAV_4557|M.avium_104 HGAQPACNRVAVPVDLRHDWPEALRQAGFDASAPSVWSAEGLMPYLPAAA
MAB_3886c|M.abscessus_ATCC_199 QGATPRIRHVPVAVDLRDDWPAALRAGGFDVGRPAAWIAEGLLPYLPPAA
Mb3793c|M.bovis_AF2122/97 HGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRYLPARA
Rv3767c|M.tuberculosis_H37Rv HGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRYLPARA
:* * *.:*** *** ** *** .* ****: ***. *
MSMEG_0095|M.smegmatis_MC2_155 QDRLFELVTELSAPGSRIAVETAGVAATD------RREAMRERFKKFADQ
TH_4502|M.thermoresistible__bu QDRLFENITALSAPGSRLAVETAAEEPVD------RREQMRARMERIASQ
Mflv_0743|M.gilvum_PYR-GCK QDRLFAQITELSAPGSQVAAESMGVHAPD------RRERMRERFASIASQ
Mvan_0104|M.vanbaalenii_PYR-1 QDRLFAQITELSAPGSRVAAESMGIHAQD------RRERMRERFASITAQ
MLBr_02640|M.leprae_Br4923 QDGLFTEIGGLSAVGSRIAVETSPLHGDE------WREQMQLRFRRVSDA
MMAR_0955|M.marinum_M QDLLFERVQGLTVRASRIAVEALGPKFLDPQVRANRSARMERIRAVMAHV
MUL_0706|M.ulcerans_Agy99 QDLLFERVQGLTVRASRIAVEALGPKFLDPQVRANRSARIERIRAVMAHV
MAV_4557|M.avium_104 QDLLFDRIQGLTVAGSRVAVEALGPKFLDPQARAKRRERMDRIQALMARI
MAB_3886c|M.abscessus_ATCC_199 QDLLFERIDTLSAPGSRIAVENFGEDFFNPETLARQRERGQAFRRVAEEM
Mb3793c|M.bovis_AF2122/97 QDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAAAAKL
Rv3767c|M.tuberculosis_H37Rv QDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAAAAKL
** ** : *: .* :* : :
MSMEG_0095|M.smegmatis_MC2_155 LNLSSALDIQELVYDDPDRADVAEWLDAHGWRARGVHALDEMRRLDRL--
TH_4502|M.thermoresistible__bu FGLEKALDVAQLMYDDPDRADVPEWLTGHGWRTEWVSAPDEMRRLDRF--
Mflv_0743|M.gilvum_PYR-GCK IDIEP-MDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRLDRY--
Mvan_0104|M.vanbaalenii_PYR-1 FDVEP-MDITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMRRLHRL--
MLBr_02640|M.leprae_Br4923 LGFEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGD
MMAR_0955|M.marinum_M EPQREIPRTDELWYFE-EREDVGDWFRRHDWDVTVTPSGELMAGYGRA--
MUL_0706|M.ulcerans_Agy99 EPQREIPRTDELWYFE-EREDVGDWFRRHDWDVTVTPSGELMAGYGRA--
MAV_4557|M.avium_104 DPDRAVPRTDELWYFE-EREDVGEWFGRHGWDVRVTPSDELMAGYGRP--
MAB_3886c|M.abscessus_ATCC_199 QGQ-DIPDVADLWYLE-ERTDAGEFLAGRGWRVTSETAVALLGRHGRD--
Mb3793c|M.bovis_AF2122/97 VET-EISDVDDLWYAE-QRTAVAEWLRERGWDVSTATLPELLARYGRS--
Rv3767c|M.tuberculosis_H37Rv VET-EISDVDDLWYAE-QRTAVAEWLRERGWDVSTATLPELLARYGRS--
:* * : :* . ::: :.* . : *
MSMEG_0095|M.smegmatis_MC2_155 -VELPDDP---------DRAAFSTFVTAQRL--
TH_4502|M.thermoresistible__bu -VAAAMPPGDDADAADLDDTAFSKFVTAERPS-
Mflv_0743|M.gilvum_PYR-GCK -VEVADSD----------GQSFSTFTTGTKL--
Mvan_0104|M.vanbaalenii_PYR-1 -VEIADGD----------DQSFSTFTTAVKR--
MLBr_02640|M.leprae_Br4923 GVPMADDK-----------DAFAEFVTAHRL--
MMAR_0955|M.marinum_M -AAAQVED----------RVPTNLFVAAQRK--
MUL_0706|M.ulcerans_Agy99 -AAAQVED----------RVPTNLFVAAQRN--
MAV_4557|M.avium_104 -APAEVRD----------FVPGNLFVAAQRR--
MAB_3886c|M.abscessus_ATCC_199 -IPADLPD----------ATPNSAFLFAQKAD-
Mb3793c|M.bovis_AF2122/97 -IPHSGED----------SIPPNLFVSAQRATS
Rv3767c|M.tuberculosis_H37Rv -IPHSGED----------SIPPNLFVSAQRATS
. * . :