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RFRGPLIGLSVFMVIALAMTWLVYATLRREVAGSTNDYSAMFTDATGLRDGDDVRIAGVRVGRVESVAID GDLARVDFRVETEQPLYGNTIATITYQNIVGQRYLGLSMGKTGSTDRLKPGSVIPLEQTEPSFDIGMLLH GFEPLFSVLDPTQVDNLTDGVVKSLQGDTGSIVGLVDQTSQLTETFAGRDKVLDDVITNLNGLTQTLAGQ NKNLDSVLTHTREMVAILDNRRGALVDSVGSTAFAVRRLSNISDTVYPQLNEILHREPGFVSHLNTVEPQ LAFAGANLPLLLKGVARTTQEGAFINGYVCDLNITGFFPGLNDVVPIIVNAATPGNKAQYTPKCRNLADG *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4567c | - | - | 100% (351) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_1009c | - | e-135 | 66.48% (352) | putative MCE family protein |
| M. abscessus ATCC 19977 | MAB_4515c | - | e-128 | 63.94% (355) | putative Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0176 | mce1B | 2e-42 | 31.74% (334) | MCE-family protein MCE1B |
| M. gilvum PYR-GCK | Mflv_0009 | - | 1e-130 | 63.53% (351) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv0170 | mce1B | 7e-43 | 31.74% (334) | MCE-family protein MCE1B |
| M. leprae Br4923 | MLBr_02590 | mce1B | 2e-47 | 33.33% (327) | putative secreted protein |
| M. marinum M | MMAR_3865 | mce5B | 1e-132 | 64.10% (351) | Mce family protein, Mce5B |
| M. avium 104 | MAV_2387 | - | 1e-126 | 62.39% (351) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_1144 | - | 1e-130 | 62.68% (351) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_3156 | - | 1e-128 | 63.25% (351) | PUTATIVE virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_3797 | mce5B | 1e-131 | 63.82% (351) | Mce family protein, Mce5B |
| M. vanbaalenii PYR-1 | Mvan_0960 | - | 1e-131 | 64.96% (351) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3865|M.marinum_M MKFRGPLIGLSLFMVVAVALTWMVYVSLRREVAGKTVAYAAVFTDVYGLR
MUL_3797|M.ulcerans_Agy99 MKFRGPLIGLSLFMVVAVALTWMVYVSLRREVAGKTVAYAAVFTDVYGLR
MAV_2387|M.avium_104 MRFRGPLIALTLFMIVSLTLTWLVYVSLRRDVAGDTARYSAVFSDVYGLR
Mflv_0009|M.gilvum_PYR-GCK MKYRGPLIGLSLFMIVAITLTWLVYVTLRRDVAGEKVPYSAMFTDVFGLR
Mvan_0960|M.vanbaalenii_PYR-1 MKYRGALVGLSLFMVVAVTLTWLVYVTLRRDVAGSTAPYAAVFTDVFGLR
MSMEG_1144|M.smegmatis_MC2_155 MKIRGALIGLSLFMVVALTLTWMVYVTLRRDVAGRTVPYTAVFTDVFGLR
TH_3156|M.thermoresistible__bu MRSRGALIGLSLFMAVAVVLTWLVYVTLRRDVAGSTVPYSAVFTDVFGLR
MAB_4567c|M.abscessus_ATCC_199 MRFRGPLIGLSVFMVIALAMTWLVYATLRREVAGSTNDYSAMFTDATGLR
Mb0176|M.bovis_AF2122/97 MKITGTVVKLGIVSVVLLFFTVMIIVIFGQMRFDRTNGYTAEFSNVSGLR
Rv0170|M.tuberculosis_H37Rv MKITGTVVKLGIVSVVLLFFTVMIIVIFGQMRFDRTNGYTAEFSNVSGLR
MLBr_02590|M.leprae_Br4923 MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFTNISGLR
*: *.:: * :. : : :* :: . : : . . *:* *:: ***
MMAR_3865|M.marinum_M EGDDVRMAGVRVGRVEKIDLE--GKLAKVRFVVQNEQRLFGNTVASVTYQ
MUL_3797|M.ulcerans_Agy99 EGDGVRMAGVRVGRVEKIDLE--GKLAKVRFVVQNEQRLFGNTVASVTYQ
MAV_2387|M.avium_104 EGDDVRMAGVRVGRVEKIELD--GKLAKVSFVVQSEQRLYGNTLASVTYQ
Mflv_0009|M.gilvum_PYR-GCK EGDDVRMAGVRVGRVEKIELD--GKLAKVSFVVQGDQQVLGTTVASVTYQ
Mvan_0960|M.vanbaalenii_PYR-1 EGDDVRMAGVRVGRVEKIELQ--GDLAKVSFVVQNDQQVLGTTVASVTYQ
MSMEG_1144|M.smegmatis_MC2_155 EGDDVRMAGVRVGRVEKIELD--GKHAKVSFVVQADQQVFGNTVASVTYQ
TH_3156|M.thermoresistible__bu EGDDVRMAGVRVGRVERIELD--GKYAKVSFVVQSDQQVLGNTVASVTYQ
MAB_4567c|M.abscessus_ATCC_199 DGDDVRIAGVRVGRVESVAID--GDLARVDFRVETEQPLYGNTIATITYQ
Mb0176|M.bovis_AF2122/97 QGQFVRASGVEIGKVKALHLVDGGRRVRVEFNIDRSVPLYQSTTAQIRYS
Rv0170|M.tuberculosis_H37Rv QGQFVRASGVEIGKVKALHLVDGGRRVRVEFNIDRSVPLYQSTTAQIRYS
MLBr_02590|M.leprae_Br4923 TGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTTAQIRYL
*: ** :**.:*:*: : : * .:* * :: . : .* * : *
MMAR_3865|M.marinum_M NIVGQRYLGLSLGK-KGSPDQLAPGSVIPVQRTEPSFDVTALLNGYEPLF
MUL_3797|M.ulcerans_Agy99 NIVGQRYLGLSLGK-KGSPDQLAPGSVIPVQRTEPSFDVTALLNGYEPLF
MAV_2387|M.avium_104 NIVGQRYLGLSLGK-EGNPAQLPPGSTIPLERTEPSFDVTTLLNGYEPLF
Mflv_0009|M.gilvum_PYR-GCK NIVGQRYLGLTLGS-QGEPVPLPAGSVLPLERSDPSFDVTTLLNGYEPLF
Mvan_0960|M.vanbaalenii_PYR-1 NIVGQRYLGLSLGN-TGDPRPLPAGSVIPLERSEASFDVTTLLNGYEPLF
MSMEG_1144|M.smegmatis_MC2_155 NIVGQRYLGLSLGK-EGDPTLLAAGSVIPLERTDPSFDVGTLLNGYEPLF
TH_3156|M.thermoresistible__bu NIVGQRYLGLSLGN-LGDPHPLPPGATIPVEQTDPSFDVGALLNGYEPLF
MAB_4567c|M.abscessus_ATCC_199 NIVGQRYLGLSMGK-TGSTDRLKPGSVIPLEQTEPSFDIGMLLHGFEPLF
Mb0176|M.bovis_AF2122/97 DLIGNRYVELKRGEGKGANDLLPPGGLIPLSRTSPALDLDALIGGFKPVF
Rv0170|M.tuberculosis_H37Rv DLIGNRYVELKRGEGKGANDLLPPGGLIPLSRTSPALDLDALIGGFKPVF
MLBr_02590|M.leprae_Br4923 DLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIGGFKPLF
:::*:**: *. *. * : .*. :*:.::..::*: *: *::*:*
MMAR_3865|M.marinum_M SLLNPRDADNLTKGIIESLQGDTASLATLVSQTSTLTETFAGRDQALGDV
MUL_3797|M.ulcerans_Agy99 SLLNPRDADNLTKGIIESLQGDTASLATLVSQTSTLTETFAGRDQALGDV
MAV_2387|M.avium_104 SLLNPHDADNLTKGIIASLQGDTSSLATLVGQTSTLTQTFAGRDQALGNV
Mflv_0009|M.gilvum_PYR-GCK SLLDPQAADDLTQGVIQSLQGDEASLVALVDQTSQLTESFAGHDEELGAV
Mvan_0960|M.vanbaalenii_PYR-1 SLLNPRDADNLTQGVIQSLQGDEASIVGLVDQTSQLTESLAGRDEELGTV
MSMEG_1144|M.smegmatis_MC2_155 SVLDPKYANNLTEGVIQSLQGDQGSITALIDQTAQLTEAFAGREEELGSV
TH_3156|M.thermoresistible__bu SVLDPKHADNLTKGVIESLQGDEASITALVDQTAQLTEAFAGRDEELGAV
MAB_4567c|M.abscessus_ATCC_199 SVLDPTQVDNLTDGVVKSLQGDTGSIVGLVDQTSQLTETFAGRDKVLDDV
Mb0176|M.bovis_AF2122/97 RALDPAKVNNIANALITVFQGQGGTINDTLDQTAQLTSQIAERDQAIGEV
Rv0170|M.tuberculosis_H37Rv RALDPAKVNNIANALITVFQGQGGTINDILDQTAQLTSQIAERDQAIGEV
MLBr_02590|M.leprae_Br4923 RALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERDQAIGEV
*:* : ::..:: :**: .:: :.**: ** :. ::: :. *
MMAR_3865|M.marinum_M ITNLNKVIYNLAQQNDNLDGVITDTREVVSTLDQRRPELVSSIGSLARVL
MUL_3797|M.ulcerans_Agy99 ITNLNKVIYNLAQQNDNLDGVITDTREVVSTLDQRRPELVSSIGSLARVL
MAV_2387|M.avium_104 ITNLNKVVGNLAAQNDNLDGVITQTRSVVGELDRRRPDLVASVGSLARLS
Mflv_0009|M.gilvum_PYR-GCK ITDLNTVMSNLAKHNDSMDQVLTETQAAVSIFDAQRQELVDSTGSISRVV
Mvan_0960|M.vanbaalenii_PYR-1 ITDLNAVMGNLARHNDSLDQVLTQVQSAVTTFDGQRQELVDSTGSMARVV
MSMEG_1144|M.smegmatis_MC2_155 ITDLNAVAANLARHNDDLDHIVSEAQSVVATFEARRPELVESMGSIAKVV
TH_3156|M.thermoresistible__bu ITDLNTVVANLARHNDDLDHVIGEARSVVSTFDDRRDQLIDSMGSAAKVI
MAB_4567c|M.abscessus_ATCC_199 ITNLNGLTQTLAGQNKNLDSVLTHTREMVAILDNRRGALVDSVGSTAFAV
Mb0176|M.bovis_AF2122/97 VKNLNIVLDTTVKHRKEFDETVNNLENLITGLRNHSDQLAGGLAHISNGA
Rv0170|M.tuberculosis_H37Rv VKNLNIVLDTTVKHRKEFDETVNNLENLITGLRNHSDQLAGGLAHISNGA
MLBr_02590|M.leprae_Br4923 VKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFAHISNAA
:.:** : . . :...:* : . . : : : * . . :
MMAR_3865|M.marinum_M ERLSASANDVYPQLREFIDRQPGATRHILSVEPQVAFFGDNIPLLLKGLT
MUL_3797|M.ulcerans_Agy99 ERLSASANDVYPQLREFIDRQPGATRHILSVEPQVAFFGDNIPLLLKGLT
MAV_2387|M.avium_104 DRLSASAADVYPALREFIDRQPGVTKHIMDVEPQVAFFGDNIPLLLKGLT
Mflv_0009|M.gilvum_PYR-GCK SRLSTVSDDVYPSLNELIEREPGFAQHLVSIEPQLAFTGANLPLLLKGFA
Mvan_0960|M.vanbaalenii_PYR-1 RQLSTISDEVYPSLNELITREPGFTQHMVSIEPQLAFTGANLPLLLKGFA
MSMEG_1144|M.smegmatis_MC2_155 RQLSTISDEVYPSLSEMVQRQPGFAAHMLGIEPQLAFVGANLPLMLKGFA
TH_3156|M.thermoresistible__bu RQLSAISDEVYQPLNEMVQREPGFAKHMLGIEPQLAFVGANLPLMLKGFA
MAB_4567c|M.abscessus_ATCC_199 RRLSNISDTVYPQLNEILHREPGFVSHLNTVEPQLAFAGANLPLLLKGVA
Mb0176|M.bovis_AF2122/97 GTVADLLAENRTLVRKAVSYLDAIQQPVIDQRVELDDLLHKTPTALTALG
Rv0170|M.tuberculosis_H37Rv GTVADLLAENRTLVRKAVSYLDAIQQPVIDQRVELDDLLHKTPTALTALG
MLBr_02590|M.leprae_Br4923 GTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPTVLNQIG
:: : : : . : . :: : * *. .
MMAR_3865|M.marinum_M RVG-NRGAYGNAYVCDINAFGFFPGLNDVMPIIVNAATPGNQARHTPRCR
MUL_3797|M.ulcerans_Agy99 RVG-NRGAYGNAYVCDINAFGFFPGLNDVMPIIVNAATPGNQARHTPRCR
MAV_2387|M.avium_104 RVG-NQGAYGNAYVCDVNFMGFFPGLNDVVPIIINAATPGNRAWHTPRCR
Mflv_0009|M.gilvum_PYR-GCK RIT-SEGAYANAYACDLNATGFFPGLNDVTPIIVDAATPGNDAQYSPKCR
Mvan_0960|M.vanbaalenii_PYR-1 RIT-GEGAYANAYACDLNIQGFFPGLNDVVPIIVDAATPGNDARYTPKCR
MSMEG_1144|M.smegmatis_MC2_155 RIT-QEGTYANAYLCDLNATAFFPGLNDVTPIIVDAATPGNKAQHTPKCR
TH_3156|M.thermoresistible__bu RVT-GEGTYANAYACNLDGTAFFPGLNDITPIIVAAATPGNKARYTPKCR
MAB_4567c|M.abscessus_ATCC_199 RTT-QEGAFINGYVCDLNITGFFPGLNDVVPIIVNAATPGNKAQYTPKCR
Mb0176|M.bovis_AF2122/97 RANGTYGDFQNFYLCDLQIK--WNGFQAGGPVRTVKLFSQPTGRCTPQ--
Rv0170|M.tuberculosis_H37Rv RANGTYGDFQNFYLCDLQIK--WNGFQAGGPVRTVKLFSQPTGRCTPQ--
MLBr_02590|M.leprae_Br4923 RTIGSYGDFVNFYSCDITLK--INGLQPGGPVRTVRLFQQPTGRCTPQ--
* * : * * *:: *:: *: . :*:
MMAR_3865|M.marinum_M SMADG
MUL_3797|M.ulcerans_Agy99 SMADG
MAV_2387|M.avium_104 STVDG
Mflv_0009|M.gilvum_PYR-GCK NMANG
Mvan_0960|M.vanbaalenii_PYR-1 NMANG
MSMEG_1144|M.smegmatis_MC2_155 SMANG
TH_3156|M.thermoresistible__bu NLANG
MAB_4567c|M.abscessus_ATCC_199 NLADG
Mb0176|M.bovis_AF2122/97 -----
Rv0170|M.tuberculosis_H37Rv -----
MLBr_02590|M.leprae_Br4923 -----