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RFRGPLIGLTVFMTVALTLGWLVYATLLREVSGSTTAYSAIFTDVYGLREGDDVRMAGVRVGRVQKIELV DNERARVDFVVQNDQKLYGNTIASVTYQNIVGQRYVGLSPGKSGGPAGDTVLAAGATIPVERTDPSFDVT TLLNGYEPLFSTLSPEQADNLTKGVIQSLQGDNASIVTLVSQTSTLTKAFAGRDQALGNAITSLNTVTGN LAQQNASLDKVLTQTRQMVSDLDSRRPELVSSAGSLAQTMRRLSKITNDVFPSLEEIITRQPGFTNHVVG IEPQYAFLGDNLPIVLKGLSRFYSEGAFINVYMCDLNLTGFFPGLNDVIPIIVNAATPGNVAQYTPRCRN MANG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4515c | - | - | 100% (355) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_1009c | - | e-162 | 79.44% (355) | putative MCE family protein |
| M. abscessus ATCC 19977 | MAB_4567c | - | e-128 | 63.94% (355) | putative Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0605 | mce2B | 4e-44 | 33.03% (327) | MCE-family protein MCE2B |
| M. gilvum PYR-GCK | Mflv_0009 | - | 1e-133 | 65.63% (355) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv0590 | mce2B | 4e-41 | 36.92% (260) | MCE-family protein MCE2B |
| M. leprae Br4923 | MLBr_02590 | mce1B | 6e-42 | 28.88% (329) | putative secreted protein |
| M. marinum M | MMAR_3865 | mce5B | 1e-140 | 68.45% (355) | Mce family protein, Mce5B |
| M. avium 104 | MAV_2387 | - | 1e-138 | 67.89% (355) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_1144 | - | 1e-133 | 64.23% (355) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_3156 | - | 1e-127 | 63.66% (355) | PUTATIVE virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_3797 | mce5B | 1e-139 | 68.17% (355) | Mce family protein, Mce5B |
| M. vanbaalenii PYR-1 | Mvan_0960 | - | 1e-134 | 66.20% (355) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3865|M.marinum_M MKFRGPLIGLSLFMVVAVALTWMVYVSLRREVAGKTVAYAAVFTDVYGLR
MUL_3797|M.ulcerans_Agy99 MKFRGPLIGLSLFMVVAVALTWMVYVSLRREVAGKTVAYAAVFTDVYGLR
MAV_2387|M.avium_104 MRFRGPLIALTLFMIVSLTLTWLVYVSLRRDVAGDTARYSAVFSDVYGLR
MAB_4515c|M.abscessus_ATCC_199 MRFRGPLIGLTVFMTVALTLGWLVYATLLREVSGSTTAYSAIFTDVYGLR
Mflv_0009|M.gilvum_PYR-GCK MKYRGPLIGLSLFMIVAITLTWLVYVTLRRDVAGEKVPYSAMFTDVFGLR
Mvan_0960|M.vanbaalenii_PYR-1 MKYRGALVGLSLFMVVAVTLTWLVYVTLRRDVAGSTAPYAAVFTDVFGLR
MSMEG_1144|M.smegmatis_MC2_155 MKIRGALIGLSLFMVVALTLTWMVYVTLRRDVAGRTVPYTAVFTDVFGLR
TH_3156|M.thermoresistible__bu MRSRGALIGLSLFMAVAVVLTWLVYVTLRRDVAGSTVPYSAVFTDVFGLR
Mb0605|M.bovis_AF2122/97 MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHTTGYSAVFTHVSGLR
Rv0590|M.tuberculosis_H37Rv MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHTTGYSAVFTHVSGLR
MLBr_02590|M.leprae_Br4923 MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFTNISGLR
*: *. : * :. * : :: . : : . *:* *:.: ***
MMAR_3865|M.marinum_M EGDDVRMAGVRVGRVEKIDLEG--KLAKVRFVVQNEQRLFGNTVASVTYQ
MUL_3797|M.ulcerans_Agy99 EGDGVRMAGVRVGRVEKIDLEG--KLAKVRFVVQNEQRLFGNTVASVTYQ
MAV_2387|M.avium_104 EGDDVRMAGVRVGRVEKIELDG--KLAKVSFVVQSEQRLYGNTLASVTYQ
MAB_4515c|M.abscessus_ATCC_199 EGDDVRMAGVRVGRVQKIELVDN-ERARVDFVVQNDQKLYGNTIASVTYQ
Mflv_0009|M.gilvum_PYR-GCK EGDDVRMAGVRVGRVEKIELDG--KLAKVSFVVQGDQQVLGTTVASVTYQ
Mvan_0960|M.vanbaalenii_PYR-1 EGDDVRMAGVRVGRVEKIELQG--DLAKVSFVVQNDQQVLGTTVASVTYQ
MSMEG_1144|M.smegmatis_MC2_155 EGDDVRMAGVRVGRVEKIELDG--KHAKVSFVVQADQQVFGNTVASVTYQ
TH_3156|M.thermoresistible__bu EGDDVRMAGVRVGRVERIELDG--KYAKVSFVVQSDQQVLGNTVASVTYQ
Mb0605|M.bovis_AF2122/97 AGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATTASIRYL
Rv0590|M.tuberculosis_H37Rv AGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATTASIRYL
MLBr_02590|M.leprae_Br4923 TGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTTAQIRYL
*: ** :**.**:* : * . . * * *: . : * *.: *
MMAR_3865|M.marinum_M NIVGQRYLGLSLGKKGSPD---QLAPGSVIPVQRTEPSFDVTALLNGYEP
MUL_3797|M.ulcerans_Agy99 NIVGQRYLGLSLGKKGSPD---QLAPGSVIPVQRTEPSFDVTALLNGYEP
MAV_2387|M.avium_104 NIVGQRYLGLSLGKEGNPA---QLPPGSTIPLERTEPSFDVTTLLNGYEP
MAB_4515c|M.abscessus_ATCC_199 NIVGQRYVGLSPGKSGGPAGDTVLAAGATIPVERTDPSFDVTTLLNGYEP
Mflv_0009|M.gilvum_PYR-GCK NIVGQRYLGLTLGSQGEPV---PLPAGSVLPLERSDPSFDVTTLLNGYEP
Mvan_0960|M.vanbaalenii_PYR-1 NIVGQRYLGLSLGNTGDPR---PLPAGSVIPLERSEASFDVTTLLNGYEP
MSMEG_1144|M.smegmatis_MC2_155 NIVGQRYLGLSLGKEGDPT---LLAAGSVIPLERTDPSFDVGTLLNGYEP
TH_3156|M.thermoresistible__bu NIVGQRYLGLSLGNLGDPH---PLPPGATIPVEQTDPSFDVGALLNGYEP
Mb0605|M.bovis_AF2122/97 NLIGDRYLELGRG---HSGQR--LAPGATIPLEHTHPALDLDALLGGFRP
Rv0590|M.tuberculosis_H37Rv NLIGDRYLELGRG---HSGQR--LAPGATIPLEHTHPALDLDALLGGFRP
MLBr_02590|M.leprae_Br4923 DLIGNRYLELKHGEGQGSEKI--MPAGGLIPLSRTSPALDLDALIGGFKP
:::*:**: * * . :..*. :*:.:: .::*: :*:.*:.*
MMAR_3865|M.marinum_M LFSLLNPRDADNLTKGIIESLQGDTASLATLVSQTSTLTETFAGRDQALG
MUL_3797|M.ulcerans_Agy99 LFSLLNPRDADNLTKGIIESLQGDTASLATLVSQTSTLTETFAGRDQALG
MAV_2387|M.avium_104 LFSLLNPHDADNLTKGIIASLQGDTSSLATLVGQTSTLTQTFAGRDQALG
MAB_4515c|M.abscessus_ATCC_199 LFSTLSPEQADNLTKGVIQSLQGDNASIVTLVSQTSTLTKAFAGRDQALG
Mflv_0009|M.gilvum_PYR-GCK LFSLLDPQAADDLTQGVIQSLQGDEASLVALVDQTSQLTESFAGHDEELG
Mvan_0960|M.vanbaalenii_PYR-1 LFSLLNPRDADNLTQGVIQSLQGDEASIVGLVDQTSQLTESLAGRDEELG
MSMEG_1144|M.smegmatis_MC2_155 LFSVLDPKYANNLTEGVIQSLQGDQGSITALIDQTAQLTEAFAGREEELG
TH_3156|M.thermoresistible__bu LFSVLDPKHADNLTKGVIESLQGDEASITALVDQTAQLTEAFAGRDEELG
Mb0605|M.bovis_AF2122/97 LFQTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRDHAIG
Rv0590|M.tuberculosis_H37Rv LFQTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRDHAIG
MLBr_02590|M.leprae_Br4923 LFRALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERDQAIG
** *.* : ::..:: :**: .:: ::.**: ** ::. ::. :*
MMAR_3865|M.marinum_M DVITNLNKVIYNLAQQNDNLDGVITDTREVVSTLDQRRPELVSSIGSLAR
MUL_3797|M.ulcerans_Agy99 DVITNLNKVIYNLAQQNDNLDGVITDTREVVSTLDQRRPELVSSIGSLAR
MAV_2387|M.avium_104 NVITNLNKVVGNLAAQNDNLDGVITQTRSVVGELDRRRPDLVASVGSLAR
MAB_4515c|M.abscessus_ATCC_199 NAITSLNTVTGNLAQQNASLDKVLTQTRQMVSDLDSRRPELVSSAGSLAQ
Mflv_0009|M.gilvum_PYR-GCK AVITDLNTVMSNLAKHNDSMDQVLTETQAAVSIFDAQRQELVDSTGSISR
Mvan_0960|M.vanbaalenii_PYR-1 TVITDLNAVMGNLARHNDSLDQVLTQVQSAVTTFDGQRQELVDSTGSMAR
MSMEG_1144|M.smegmatis_MC2_155 SVITDLNAVAANLARHNDDLDHIVSEAQSVVATFEARRPELVESMGSIAK
TH_3156|M.thermoresistible__bu AVITDLNTVVANLARHNDDLDHVIGEARSVVSTFDDRRDQLIDSMGSAAK
Mb0605|M.bovis_AF2122/97 EVVNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAAHISS
Rv0590|M.tuberculosis_H37Rv EVVNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAAHISS
MLBr_02590|M.leprae_Br4923 EVVKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFAHISN
.:..** * . . :. .:* : . . : :. : * : . :
MMAR_3865|M.marinum_M VLERLSASANDVYPQLREFIDRQPGATRHILSVEPQVAFFGDNIPLLLKG
MUL_3797|M.ulcerans_Agy99 VLERLSASANDVYPQLREFIDRQPGATRHILSVEPQVAFFGDNIPLLLKG
MAV_2387|M.avium_104 LSDRLSASAADVYPALREFIDRQPGVTKHIMDVEPQVAFFGDNIPLLLKG
MAB_4515c|M.abscessus_ATCC_199 TMRRLSKITNDVFPSLEEIITRQPGFTNHVVGIEPQYAFLGDNLPIVLKG
Mflv_0009|M.gilvum_PYR-GCK VVSRLSTVSDDVYPSLNELIEREPGFAQHLVSIEPQLAFTGANLPLLLKG
Mvan_0960|M.vanbaalenii_PYR-1 VVRQLSTISDEVYPSLNELITREPGFTQHMVSIEPQLAFTGANLPLLLKG
MSMEG_1144|M.smegmatis_MC2_155 VVRQLSTISDEVYPSLSEMVQRQPGFAAHMLGIEPQLAFVGANLPLMLKG
TH_3156|M.thermoresistible__bu VIRQLSAISDEVYQPLNEMVQREPGFAKHMLGIEPQLAFVGANLPLMLKG
Mb0605|M.bovis_AF2122/97 AAGTLADLLGADRPLLHSSFGHLEGIQQPLIDELAELDHVLGKLPDAYRI
Rv0590|M.tuberculosis_H37Rv AAGTLADLLG--------------------------------------RI
MLBr_02590|M.leprae_Br4923 AAGTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPTVLNQ
:: .
MMAR_3865|M.marinum_M LTRVGNR-GAYGNAYVCDINAFGFFPGLNDVMPIIVNAATPGNQARHTPR
MUL_3797|M.ulcerans_Agy99 LTRVGNR-GAYGNAYVCDINAFGFFPGLNDVMPIIVNAATPGNQARHTPR
MAV_2387|M.avium_104 LTRVGNQ-GAYGNAYVCDVNFMGFFPGLNDVVPIIINAATPGNRAWHTPR
MAB_4515c|M.abscessus_ATCC_199 LSRFYSE-GAFINVYMCDLNLTGFFPGLNDVIPIIVNAATPGNVAQYTPR
Mflv_0009|M.gilvum_PYR-GCK FARITSE-GAYANAYACDLNATGFFPGLNDVTPIIVDAATPGNDAQYSPK
Mvan_0960|M.vanbaalenii_PYR-1 FARITGE-GAYANAYACDLNIQGFFPGLNDVVPIIVDAATPGNDARYTPK
MSMEG_1144|M.smegmatis_MC2_155 FARITQE-GTYANAYLCDLNATAFFPGLNDVTPIIVDAATPGNKAQHTPK
TH_3156|M.thermoresistible__bu FARVTGE-GTYANAYACNLDGTAFFPGLNDITPIIVAAATPGNKARYTPK
Mb0605|M.bovis_AF2122/97 IGRAGGIYGDFFNFYLCDI--SLKVNGLQPGGPVRTVKLFGQPTGRCTPQ
Rv0590|M.tuberculosis_H37Rv VHCCT------------------AASGTSRASSSRS--------------
MLBr_02590|M.leprae_Br4923 IGRTIGSYGDFVNFYSCDI--TLKINGLQPGGPVRTVRLFQQPTGRCTPQ
. * . .
MMAR_3865|M.marinum_M CRSMADG
MUL_3797|M.ulcerans_Agy99 CRSMADG
MAV_2387|M.avium_104 CRSTVDG
MAB_4515c|M.abscessus_ATCC_199 CRNMANG
Mflv_0009|M.gilvum_PYR-GCK CRNMANG
Mvan_0960|M.vanbaalenii_PYR-1 CRNMANG
MSMEG_1144|M.smegmatis_MC2_155 CRSMANG
TH_3156|M.thermoresistible__bu CRNLANG
Mb0605|M.bovis_AF2122/97 -------
Rv0590|M.tuberculosis_H37Rv -------
MLBr_02590|M.leprae_Br4923 -------