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M. thermoresistible (build 8) TH_3156 (-)

annotation: virulence factor Mce family protein
coordinates: 4664784 - 4665839
length: 352

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3156--100% (352)virulence factor Mce family protein
M. thermoresistible (build 8)TH_3551-2e-4431.70% (347) PUTATIVE virulence factor Mce family protein
M. thermoresistible (build 8)TH_2617-4e-4430.55% (347) PUTATIVE virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0605mce2B2e-4233.86% (316) MCE-family protein MCE2B
M. gilvum PYR-GCKMflv_0009-1e-15574.36% (351) virulence factor Mce family protein
M. tuberculosis H37RvRv0590mce2B2e-4139.50% (238) MCE-family protein MCE2B
M. leprae Br4923MLBr_02590mce1B3e-4329.60% (348) putative secreted protein
M. abscessus ATCC 19977MAB_1009c-1e-13969.03% (352) putative MCE family protein
M. marinum MMMAR_3865mce5B1e-13666.10% (351) Mce family protein, Mce5B
M. avium 104MAV_0103-1e-13264.04% (356) virulence factor Mce family protein
M. smegmatis MC2 155MSMEG_1144-1e-16681.48% (351) virulence factor Mce family protein
M. ulcerans Agy99MUL_3797mce5B1e-13565.81% (351) Mce family protein, Mce5B
M. vanbaalenii PYR-1Mvan_0960-1e-15776.64% (351) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3156|M.thermoresistible__bu      MRSRGALIGLSLFMAVAVVLTWLVYVTLRRDVAGSTVPYSAVFTDVFGLR
MSMEG_1144|M.smegmatis_MC2_155      MKIRGALIGLSLFMVVALTLTWMVYVTLRRDVAGRTVPYTAVFTDVFGLR
Mflv_0009|M.gilvum_PYR-GCK          MKYRGPLIGLSLFMIVAITLTWLVYVTLRRDVAGEKVPYSAMFTDVFGLR
Mvan_0960|M.vanbaalenii_PYR-1       MKYRGALVGLSLFMVVAVTLTWLVYVTLRRDVAGSTAPYAAVFTDVFGLR
MAB_1009c|M.abscessus_ATCC_199      MKFRGPLIALTVFMAVALALTWLVYATLRRDVAGGTTSYSAIFTDVYGLR
MAV_0103|M.avium_104                --MRGPLIGLSLFMAIAIAVTWMVYATLRRDVAGPTTPYAAMFTDVYGLR
MMAR_3865|M.marinum_M               MKFRGPLIGLSLFMVVAVALTWMVYVSLRREVAGKTVAYAAVFTDVYGLR
MUL_3797|M.ulcerans_Agy99           MKFRGPLIGLSLFMVVAVALTWMVYVSLRREVAGKTVAYAAVFTDVYGLR
Mb0605|M.bovis_AF2122/97            MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHTTGYSAVFTHVSGLR
Rv0590|M.tuberculosis_H37Rv         MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHTTGYSAVFTHVSGLR
MLBr_02590|M.leprae_Br4923          MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFTNISGLR
                                        *. : * :.  :   .* :: . : :     .  *:* **.: ***

TH_3156|M.thermoresistible__bu      EGDDVRMAGVRVGRVERIELDG--KYAKVSFVVQSDQQVLGNTVASVTYQ
MSMEG_1144|M.smegmatis_MC2_155      EGDDVRMAGVRVGRVEKIELDG--KHAKVSFVVQADQQVFGNTVASVTYQ
Mflv_0009|M.gilvum_PYR-GCK          EGDDVRMAGVRVGRVEKIELDG--KLAKVSFVVQGDQQVLGTTVASVTYQ
Mvan_0960|M.vanbaalenii_PYR-1       EGDDVRMAGVRVGRVEKIELQG--DLAKVSFVVQNDQQVLGTTVASVTYQ
MAB_1009c|M.abscessus_ATCC_199      DGDDVRMAGVRVGRVEKIELVNN-KQAKVDFVVQNDQKLYGNTLASVTYQ
MAV_0103|M.avium_104                VGDDVRMAGVRVGRVEKVELAG--KLAKVSFIVENDQRLYGNTVASVTYQ
MMAR_3865|M.marinum_M               EGDDVRMAGVRVGRVEKIDLEG--KLAKVRFVVQNEQRLFGNTVASVTYQ
MUL_3797|M.ulcerans_Agy99           EGDGVRMAGVRVGRVEKIDLEG--KLAKVRFVVQNEQRLFGNTVASVTYQ
Mb0605|M.bovis_AF2122/97            AGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATTASIRYL
Rv0590|M.tuberculosis_H37Rv         AGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATTASIRYL
MLBr_02590|M.leprae_Br4923          TGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTTAQIRYL
                                     *: ** :**.**:*  : * .    . * * *: .  :   * *.: * 

TH_3156|M.thermoresistible__bu      NIVGQRYLGLSLGN-LGDPHPLPPGATIPVEQTDPSFDVGALLNGYEPLF
MSMEG_1144|M.smegmatis_MC2_155      NIVGQRYLGLSLGK-EGDPTLLAAGSVIPLERTDPSFDVGTLLNGYEPLF
Mflv_0009|M.gilvum_PYR-GCK          NIVGQRYLGLTLGS-QGEPVPLPAGSVLPLERSDPSFDVTTLLNGYEPLF
Mvan_0960|M.vanbaalenii_PYR-1       NIVGQRYLGLSLGN-TGDPRPLPAGSVIPLERSEASFDVTTLLNGYEPLF
MAB_1009c|M.abscessus_ATCC_199      NIVGQRYLGLSLGK-TGDTNVLAGGSTIPVERTDPSFDVTTLLNGYEPLF
MAV_0103|M.avium_104                NIIGQRYLGLSLGE-TGSRTTLSAGSVIPVQQTDPSFDVGKLLNGFEPLF
MMAR_3865|M.marinum_M               NIVGQRYLGLSLGK-KGSPDQLAPGSVIPVQRTEPSFDVTALLNGYEPLF
MUL_3797|M.ulcerans_Agy99           NIVGQRYLGLSLGK-KGSPDQLAPGSVIPVQRTEPSFDVTALLNGYEPLF
Mb0605|M.bovis_AF2122/97            NLIGDRYLELGRG---HSGQRLAPGATIPLEHTHPALDLDALLGGFRPLF
Rv0590|M.tuberculosis_H37Rv         NLIGDRYLELGRG---HSGQRLAPGATIPLEHTHPALDLDALLGGFRPLF
MLBr_02590|M.leprae_Br4923          DLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIGGFKPLF
                                    :::*:*** *  *    .   :. *. :*:.:: .::*:  *:.*:.***

TH_3156|M.thermoresistible__bu      SVLDPKHADNLTKGVIESLQGDEASITALVDQTAQLTEAFAGRDEELGAV
MSMEG_1144|M.smegmatis_MC2_155      SVLDPKYANNLTEGVIQSLQGDQGSITALIDQTAQLTEAFAGREEELGSV
Mflv_0009|M.gilvum_PYR-GCK          SLLDPQAADDLTQGVIQSLQGDEASLVALVDQTSQLTESFAGHDEELGAV
Mvan_0960|M.vanbaalenii_PYR-1       SLLNPRDADNLTQGVIQSLQGDEASIVGLVDQTSQLTESLAGRDEELGTV
MAB_1009c|M.abscessus_ATCC_199      STLSPEQADNLTKGVIQSLQGDQASITSLVDQTSTLTKTFAGRDQVLGNV
MAV_0103|M.avium_104                TLLNPKDADDLTKGVLQSLQGDQASIPLLVEQTSTITKTLSARDQSLGDL
MMAR_3865|M.marinum_M               SLLNPRDADNLTKGIIESLQGDTASLATLVSQTSTLTETFAGRDQALGDV
MUL_3797|M.ulcerans_Agy99           SLLNPRDADNLTKGIIESLQGDTASLATLVSQTSTLTETFAGRDQALGDV
Mb0605|M.bovis_AF2122/97            QTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRDHAIGEV
Rv0590|M.tuberculosis_H37Rv         QTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRDHAIGEV
MLBr_02590|M.leprae_Br4923          RALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERDQAIGEV
                                      *.*   : ::..::  :**: .::  ::.**: :* ::. ::. :* :

TH_3156|M.thermoresistible__bu      ITDLNTVVANLARHNDDLDHVIGEARSVVSTFDDRRDQLIDSMGSAAKVI
MSMEG_1144|M.smegmatis_MC2_155      ITDLNAVAANLARHNDDLDHIVSEAQSVVATFEARRPELVESMGSIAKVV
Mflv_0009|M.gilvum_PYR-GCK          ITDLNTVMSNLAKHNDSMDQVLTETQAAVSIFDAQRQELVDSTGSISRVV
Mvan_0960|M.vanbaalenii_PYR-1       ITDLNAVMGNLARHNDSLDQVLTQVQSAVTTFDGQRQELVDSTGSMARVV
MAB_1009c|M.abscessus_ATCC_199      ITSLSTVTGNLAQQNDSLDKAITNTRKVVADFDSRRPELVNSVGSLAQTM
MAV_0103|M.avium_104                ISSLTRVTDTVARQNDDLDQALNQTRDAVANFDDRRAALQDDVGSIARVT
MMAR_3865|M.marinum_M               ITNLNKVIYNLAQQNDNLDGVITDTREVVSTLDQRRPELVSSIGSLARVL
MUL_3797|M.ulcerans_Agy99           ITNLNKVIYNLAQQNDNLDGVITDTREVVSTLDQRRPELVSSIGSLARVL
Mb0605|M.bovis_AF2122/97            VNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAAHISSAA
Rv0590|M.tuberculosis_H37Rv         VNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAAHISSAA
MLBr_02590|M.leprae_Br4923          VKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFAHISNAA
                                    :..*. *  . .::. .:*  : . .  :: :. :   *    .  : . 

TH_3156|M.thermoresistible__bu      RQLSAISDEVYQPLNEMVQREPGFAKHMLGIEPQLAFVGANLPLMLKGFA
MSMEG_1144|M.smegmatis_MC2_155      RQLSTISDEVYPSLSEMVQRQPGFAAHMLGIEPQLAFVGANLPLMLKGFA
Mflv_0009|M.gilvum_PYR-GCK          SRLSTVSDDVYPSLNELIEREPGFAQHLVSIEPQLAFTGANLPLLLKGFA
Mvan_0960|M.vanbaalenii_PYR-1       RQLSTISDEVYPSLNELITREPGFTQHMVSIEPQLAFTGANLPLLLKGFA
MAB_1009c|M.abscessus_ATCC_199      RRLSKITDEVYPSLDELITRQPGFAKHMVQIEPKLAFLGGNLPLLLKGLA
MAV_0103|M.avium_104                RRLSAIADDVDPSLNELITREPGFSKHLVGIEPQLAFTGDNLPLLLKGFA
MMAR_3865|M.marinum_M               ERLSASANDVYPQLREFIDRQPGATRHILSVEPQVAFFGDNIPLLLKGLT
MUL_3797|M.ulcerans_Agy99           ERLSASANDVYPQLREFIDRQPGATRHILSVEPQVAFFGDNIPLLLKGLT
Mb0605|M.bovis_AF2122/97            GTLADLLGADRPLLHSSFGHLEGIQQPLIDELAELDHVLGKLPDAYRIIG
Rv0590|M.tuberculosis_H37Rv         GTLADLLG--------------------------------------RIVH
MLBr_02590|M.leprae_Br4923          GTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPTVLNQIG
                                      ::                                          . . 

TH_3156|M.thermoresistible__bu      RVTGE-GTYANAYACNLDGTAFFPGLNDITPIIVAAATPG--------NK
MSMEG_1144|M.smegmatis_MC2_155      RITQE-GTYANAYLCDLNATAFFPGLNDVTPIIVDAATPG--------NK
Mflv_0009|M.gilvum_PYR-GCK          RITSE-GAYANAYACDLNATGFFPGLNDVTPIIVDAATPG--------ND
Mvan_0960|M.vanbaalenii_PYR-1       RITGE-GAYANAYACDLNIQGFFPGLNDVVPIIVDAATPG--------ND
MAB_1009c|M.abscessus_ATCC_199      RITGD-GAYGNAYICDLNITGFFPGLNDVVPIIVNAATPG--------NV
MAV_0103|M.avium_104                RAVSE-GSYGNAYACDLNATGFFPGLNDITTFIVNAATPGNAYPITTKNL
MMAR_3865|M.marinum_M               RVGNR-GAYGNAYVCDINAFGFFPGLNDVMPIIVNAATPG--------NQ
MUL_3797|M.ulcerans_Agy99           RVGNR-GAYGNAYVCDINAFGFFPGLNDVMPIIVNAATPG--------NQ
Mb0605|M.bovis_AF2122/97            RAGGIYGDFFNFYLCDISLKVNGLQPGGPVRTVKLFGQPT----------
Rv0590|M.tuberculosis_H37Rv         CCT----------------AASGTSRASSSRS------------------
MLBr_02590|M.leprae_Br4923          RTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQPT----------
                                                               .                      

TH_3156|M.thermoresistible__bu      ARYTPKCRNLANG
MSMEG_1144|M.smegmatis_MC2_155      AQHTPKCRSMANG
Mflv_0009|M.gilvum_PYR-GCK          AQYSPKCRNMANG
Mvan_0960|M.vanbaalenii_PYR-1       ARYTPKCRNMANG
MAB_1009c|M.abscessus_ATCC_199      AQHTPRCRNLANG
MAV_0103|M.avium_104                GWHTPRCRNMANG
MMAR_3865|M.marinum_M               ARHTPRCRSMADG
MUL_3797|M.ulcerans_Agy99           ARHTPRCRSMADG
Mb0605|M.bovis_AF2122/97            GRCTPQ-------
Rv0590|M.tuberculosis_H37Rv         -------------
MLBr_02590|M.leprae_Br4923          GRCTPQ-------