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MNASTATGTAAPSAAISAASDSDDLAAFGYKPQLHRSLGKFASFAAGFSFVSILTTIFQLFAFGFSFGGP AFFWTWPIVFLGQYMVALNFAELAARYPISGAIYQWARRLGGAAVGWFAGWFMIIAQIVTASAAAIALQV VLPTVWSGFQLIGTDSSLTSVSGASNAVLLGSLLLVATTAINAVGVNWMSRINSIGVTCEIVGVVAVVGM LFGHAERGPSVVLHTGDAGSGYPWAFLAAGLMAAYVLVGFGSASELAEETRNPRRVAPRTILSAIVVSAI GGALMILGALMAAPSLTDGQLATGGLPYVLDSKLASPFGTLLLIDVAIAVFVCTLAIQTAASRLMFSMAR DGKLPFSAVLSHVNPRTGTPIAPAVVVGVCCVLILAVNFGNAALFTSLCSVCIALIYLAYLMVTTPLLLR RLGIGGSTWDANLGQTDADGRKLFSLGRCGLPINILAVGYGAFMILNLSWPRPAVFDPTGEHPYLVWMAP ICIIAVLLAGLVAYPRHTASTTEETVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4090 | - | - | 100% (517) | putative amino-acid permease |
| M. abscessus ATCC 19977 | MAB_2598 | - | 1e-23 | 29.59% (392) | hypothetical protein MAB_2598 |
| M. abscessus ATCC 19977 | MAB_3842 | - | 2e-23 | 26.25% (419) | cationic amino acid transport integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2347c | rocE | 1e-23 | 26.03% (411) | cationic amino acid transport integral membrane protein RocE |
| M. gilvum PYR-GCK | Mflv_3084 | - | 1e-124 | 49.28% (483) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv2320c | rocE | 1e-23 | 26.03% (411) | cationic amino acid transport integral membrane protein RocE |
| M. leprae Br4923 | MLBr_01304 | ansP1 | 2e-12 | 25.71% (350) | putative L-asparagine permease |
| M. marinum M | MMAR_2243 | - | 2e-25 | 25.05% (455) | cationic amino acid transport integral membrane protein |
| M. avium 104 | MAV_2087 | - | 3e-21 | 25.98% (408) | amino acid transporter |
| M. smegmatis MC2 155 | MSMEG_2184 | - | 0.0 | 68.65% (504) | amino acid permease |
| M. thermoresistible (build 8) | TH_0471 | - | 2e-19 | 28.49% (351) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_1244 | rocE | 1e-22 | 27.08% (480) | cationic amino acid transport integral membrane protein RocE |
| M. vanbaalenii PYR-1 | Mvan_1845 | - | 3e-62 | 30.74% (501) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2347c|M.bovis_AF2122/97 ---------MPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLT
Rv2320c|M.tuberculosis_H37Rv ---------MPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLT
MUL_1244|M.ulcerans_Agy99 ---------MPATSIRLREQMLRRRPAGGAPVAEGAAGSLKRSFGTFELT
MAV_2087|M.avium_104 -------------------------------MAPGTADHLRRGIGTFQLT
TH_0471|M.thermoresistible__bu ----------------MTDRLRVKSVEQSIADTDEPDSRLRKDLSWWDLT
MAB_4090|M.abscessus_ATCC_1997 ------MNASTATGTAAPSAAISAASDSDDLAAFGYKPQLHRSLGKFASF
MSMEG_2184|M.smegmatis_MC2_155 ---------MTSSATAPGPDVADPSGDHRDLAEFGYDQQLHRRLGRFESF
Mflv_3084|M.gilvum_PYR-GCK -------------------MVINQPHADSGMQDFGYKESLDRSIGKFASF
Mvan_1845|M.vanbaalenii_PYR-1 MSTTQPTSDARGRNEGDGFYDFHDKDDAAHLHALGYKSEFKRDMSPWANF
MMAR_2243|M.marinum_M ------------------------------MSQPTGEPRLRRALGVAGLV
MLBr_01304|M.leprae_Br4923 --------------MATLAESPEPKSGASRAGVLGEEAGYHKGLKPRQLQ
: :
Mb2347c|M.bovis_AF2122/97 MFGVG-ATIGTGIFFVLAQAVP-EAGPGVIVSFIIAGIAAGLAAICYAEL
Rv2320c|M.tuberculosis_H37Rv MFGVG-ATIGTGIFFVLAQAVP-EAGPGVIVSFIIAGIAAGLAAICYAEL
MUL_1244|M.ulcerans_Agy99 MFGVG-STVGTGIFFVLAEAVP-EAGPAVIVSFIIAGVAAGLAAICCAEL
MAV_2087|M.avium_104 MFGVG-STIGTGIFFVMSQAVP-EAGPAVIVSFLLAGVAAGLAAVCYAEL
TH_0471|M.thermoresistible__bu VFGVS-VVIGAGIFTVTASTAGNITGPAISVSFIIAAIACGLAALCYAEF
MAB_4090|M.abscessus_ATCC_1997 AAGFSFVSILTTIFQLFAFGFS-FGGPAFFWTWPIVFLGQYMVALNFAEL
MSMEG_2184|M.smegmatis_MC2_155 AAGFSFVSILTTIFQLFGLGFG-FGGPAFFWTWPAVFVGQFLVALCFAEL
Mflv_3084|M.gilvum_PYR-GCK AAGVSYISILTGTFQLFYFGFG-TAGPAYLWSWPLVFVGQMAVALCFMEL
Mvan_1845|M.vanbaalenii_PYR-1 SLGFTYLSPVVGIYTLFAFALA-TGGPPMIWSLVIVGVGQLLVALTFSEI
MMAR_2243|M.marinum_M AFGLAYIDPLA-MFDTFGVVSQ-TTHGHVPTAYVVTFVAMLFTAASYAVL
MLBr_01304|M.leprae_Br4923 MIGIG-GAIGTGLFLGAGGRLA-KAGPGLFLVYAVCGVFVFLILRALGEL
*. . : : :
Mb2347c|M.bovis_AF2122/97 ASAVPISGSAYSYAYTTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVN
Rv2320c|M.tuberculosis_H37Rv ASAVPISGSAYSYAYTTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVN
MUL_1244|M.ulcerans_Agy99 ASAVPVSGSSYSYAYATLGEAVAMGVASCLLLEYGVATAAVAVGLSGYVN
MAV_2087|M.avium_104 ASAVPVSGSSYSYAYTTLGEVVAMGVAACLLLEYGVATAAVSVNWSGYLN
TH_0471|M.thermoresistible__bu ASTVPVAGSAYTFSYATFGEFVAWIIGWDLILEFSVAAAVVAKGWSSYLG
MAB_4090|M.abscessus_ATCC_1997 AARYPISGAIYQWARRLGGAAVGWFAGWFMIIAQIVTASAAAIALQVVLP
MSMEG_2184|M.smegmatis_MC2_155 AARYPISGAIYQWSRRMGGEVIGWFGGWFMILAQIVTASAAAIALQVVLP
Mflv_3084|M.gilvum_PYR-GCK AAKYPVAGSVYNWSKKLASRLVGWTSGWLMLTASIVTISAVALAYQLNLP
Mvan_1845|M.vanbaalenii_PYR-1 VAQFPVAGGVYPWARRLWGRRYAWMTGWVYLVALLVTIASVAYGSGPFIA
MMAR_2243|M.marinum_M VHAYPSAGSAYTFARRSFGGNVGFLTGWALMLDYLLLPLVNYLLIGIYLN
MLBr_01304|M.leprae_Br4923 VLHRPSSGSFVSYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTAIATYLH
. * :*. :: . . . : : :
Mb2347c|M.bovis_AF2122/97 KLLSNLFGFQMPHVLSAAPWDTHPG----WVNLPAVILIGLCALLLIRGA
Rv2320c|M.tuberculosis_H37Rv KLLSNLFGFQMPHVLSAAPWDTHPG----WVNLPAVILIGLCALLLIRGA
MUL_1244|M.ulcerans_Agy99 KLLHNVFGFQLPQALSEAPWDERPGEAAGYLNLPAIILIGLCALLLIRGV
MAV_2087|M.avium_104 KLLSNVVGFQLPHALSAAPWDAQPG----YVNLPAVMLIGMCALLLIRGA
TH_0471|M.thermoresistible__bu ----EVFEFAG-ATTRLGPITLDWG---------ALLIIGFVTVLLATGT
MAB_4090|M.abscessus_ATCC_1997 TVWSGFQLIGTDSSLTSVSGASNAV-------LLGSLLLVATTAINAVGV
MSMEG_2184|M.smegmatis_MC2_155 TIWPGFQIIGDDPALTSASGATNAV-------LLGTVLLVVTTTINCLGV
Mflv_3084|M.gilvum_PYR-GCK RLWSGFQIIGDGS--GTYDYAANAV-------LLGSLLIAFTTLVNALGV
Mvan_1845|M.vanbaalenii_PYR-1 ATFGIDATVNNVIA-----FS--------------LLLLAVATAINFMGT
MMAR_2243|M.marinum_M AQFPAVPAPVF-----------------------CLAAIALVTTVNIVGV
MLBr_01304|M.leprae_Br4923 RWTIFTALPQWT---------------------LALLALAVVLVMNLISV
: : ..
Mb2347c|M.bovis_AF2122/97 SESARVNAIMVLIKLGVLGMFMIIAFSAYSADHL-KDFVP----------
Rv2320c|M.tuberculosis_H37Rv SESARVNAIMVLIKLGVLGMFMIIAFSAYSADHL-KDFVP----------
MUL_1244|M.ulcerans_Agy99 SESAKVNAIMVLIKLGVLGMFVILALTAYDTNHL-KDFAP----------
MAV_2087|M.avium_104 SESAKVNAIMVMVKLGVLVVFGILAFTAFDMHHL-DDFAP----------
TH_0471|M.thermoresistible__bu KLSANVSLAITVIKVGVVLLVVIVGAFFIKAANY-TPFIPPAEAGGEAGR
MAB_4090|M.abscessus_ATCC_1997 NWMSRINSIGVTCEIVGVVAVVGMLFGHAERGPS-VVLHTG---------
MSMEG_2184|M.smegmatis_MC2_155 KWMSRVNSAGVVCEIVGVIAVIGVFFTHAQRGPQ-VVFDTG---------
Mflv_3084|M.gilvum_PYR-GCK RLMSRINSSGVFIELIAAVLIVFLLAINVQHSPE-IFFSTNG--------
Mvan_1845|M.vanbaalenii_PYR-1 KVLAKAAIIGFSAEIIGALVVGGWLLIAHREHNIGIIFDSFG--------
MMAR_2243|M.marinum_M VIMNRLNFALVGLQLAFVLVFITVSLLYLRDHPDASLLQPLYS-------
MLBr_01304|M.leprae_Br4923 EWFGELEFWAALIKVCALMAFLVVGTIFLGGRYPVDGHNTGLS-------
. :: . .
Mb2347c|M.bovis_AF2122/97 -----------------FGVAGIGSAAGTIFFSYIGLDAVSTAGDEVKDP
Rv2320c|M.tuberculosis_H37Rv -----------------FGVAGIGSAAGTIFFSYIGLDAVSTAGDEVKDP
MUL_1244|M.ulcerans_Agy99 -----------------FGVAGVGAAAGTIFFSFIGLDAVSTAGEEVRNP
MAV_2087|M.avium_104 -----------------FGVAGVGTAAGTIFFSYIGLDAVSTAGDEVTNP
TH_0471|M.thermoresistible__bu SLDQSLFSLITGAEGSSYGWYGLLAGASIVFFAFIGFDIIATTAEETKNP
MAB_4090|M.abscessus_ATCC_1997 -----------DAG--SGYPWAFLAAGLMAAYVLVGFGSASELAEETRNP
MSMEG_2184|M.smegmatis_MC2_155 -----------HAGGQPGYIWAWIVSGLMAAYVMVGFGSAGELAEETRNP
Mflv_3084|M.gilvum_PYR-GCK ----------YGAGESMGFLGAFLIASLASGYVMYGFDTASSLGEETVEP
Mvan_1845|M.vanbaalenii_PYR-1 ------------AGGDGDYMWAFAAAALIGLYQYYGFEACGDVAEEVPDP
MMAR_2243|M.marinum_M ---------------AGFRGGDILGGAAVVALSFVGFDAVSTMAEEARNP
MLBr_01304|M.leprae_Br4923 -------LWTSHGGLFPTGVAPLIVVSSGVMFAYAAVELVGTAAGETVEP
. .. . . *. :*
Mb2347c|M.bovis_AF2122/97 QKTMPRALIAALVVVTGVYVLVALAALGTQPWQDFAEQ--ETAGLAIILD
Rv2320c|M.tuberculosis_H37Rv QKTMPRALIAALVVVTGVYVLVALAALGTQPWQDFAEQ--ETAGLAIILD
MUL_1244|M.ulcerans_Agy99 QQSVPRALIAALFVVTGVYVLVAFAALGTQPWQMFAGQ--EEAGLATILD
MAV_2087|M.avium_104 QKTMPRALIAALLTVTGVYVFVALAALGTQPWQDFGGQ--QEAGLATILD
TH_0471|M.thermoresistible__bu QRDVARGIMATLGIVTVLYVAVSLVLTGMVHYTELRAAG-ENANLATAFA
MAB_4090|M.abscessus_ATCC_1997 RRVAPRTILSAIVVSAIGGALMILGALMAAPSLTDGQL--ATGGLPYVLD
MSMEG_2184|M.smegmatis_MC2_155 RRVAPRTIRLALSVSALGGGLMILGALMAAPSLTDGRL--ATEGLPYVLD
Mflv_3084|M.gilvum_PYR-GCK RRTAPKAIARAILASFVIGGGILVFAVMAAPNLQDPQLGESSGGLQYIVQ
Mvan_1845|M.vanbaalenii_PYR-1 GRLIPKAMRRTIYIGGAAATFVCLSLILAVADIPAVIAGEDTDPVSTVLG
MMAR_2243|M.marinum_M RRTVPLAIILTVLIGGATFLSVSYCATLVEPDYRAITTP-NSAALQIVVS
MLBr_01304|M.leprae_Br4923 KKIMPRAINSVIARIAIFYVGSVILLALLLPYSAFKAS---ESPFVTFFS
: . : .: . .
Mb2347c|M.bovis_AF2122/97 NVTHGEWASTILAAGAVVSIFTVTLVTMYGQTRILFAMGRDGLLPA--RF
Rv2320c|M.tuberculosis_H37Rv NVTHGEWASTILAAGAVVSIFTVTLVTMYGQTRILFAMGRDGLLPA--RF
MUL_1244|M.ulcerans_Agy99 NVTHSAWASTVLAMGAVISIFTVTLVTMYGQTRILFAMGRDGLLPA--RF
MAV_2087|M.avium_104 HVTHGSWASTILAAGAVISIFSVTLVTMYGITRILFAMGRDGLLPP--RF
TH_0471|M.thermoresistible__bu -ANGIDWAAKVISIGALAGLTTVVIVLVLGQTRVLFAMSRDGLLPR--PL
MAB_4090|M.abscessus_ATCC_1997 SKLASPFG-TLLLIDVAIAVFVCTLAIQTAASRLMFSMARDGKLPFSAVL
MSMEG_2184|M.smegmatis_MC2_155 TVLSSPWG-TVLLIDVCIAITICTLAIQTAASRLMFSMARDGRLPASAIL
Mflv_3084|M.gilvum_PYR-GCK QVMWGPLG-TIFLACIVIAVTVCCLAVHTAAIRLTFAMARDNALPFGEKL
Mvan_1845|M.vanbaalenii_PYR-1 -EAFGPVGSKIILVIVLISFLSCAMSLQAAASRLAYSYGRDEMIMGSSLL
MMAR_2243|M.marinum_M --AGGHSLQTFFIIAYMCACSAAALSSQVSVTRILYAMGRDGVLPR-AVF
MLBr_01304|M.leprae_Br4923 KVGFYGAG-DLMNIVVLTAALSSLNAGLYATGRVMHSIAINGSGPK---F
.: . . *: .: . : :
Mb2347c|M.bovis_AF2122/97 AKVNPRTMTPVHNTVIVAIFASTLAAFIP------LDSLADMVSIGTLTA
Rv2320c|M.tuberculosis_H37Rv AKVNPRTMTPVHNTVIVAIFASTLAAFIP------LDSLADMVSIGTLTA
MUL_1244|M.ulcerans_Agy99 AAVHPRFQTPVSNTVVVAIAAAVLAALVP------LNRLADMVSIGTLTA
MAV_2087|M.avium_104 ARVNPRTMTPVNNTVIVAVAAATLAAFIP------LQNLADMVSIGTLTA
TH_0471|M.thermoresistible__bu SKTGPR-GTPVRITVLVGALVAIAASVFP------VGNLEEMVNIGTLFA
MAB_4090|M.abscessus_ATCC_1997 SHVNPRTGTPIAPAVVVGVCCVLILAVNFGNA-ALFTSLCSVCIALIYLA
MSMEG_2184|M.smegmatis_MC2_155 AKVNGRTGTPIWPSVLIGVLCIAVLLVNVGNS-AIFATLASVCIILIYLA
Mflv_3084|M.gilvum_PYR-GCK ATVNPKTQTPIVPAVTIGIISILILVINVANV-QIFTVLTSIAIIMIYLA
Mvan_1845|M.vanbaalenii_PYR-1 KKFSPTRHVPPYALLLAAVVPAVIIVGSKFST-DAITKIISFAALGIYIG
MMAR_2243|M.marinum_M GRISRRFRTPIGAALVVSAVSTLALIADL-------ETMASIVSFGALAA
MLBr_01304|M.leprae_Br4923 TARMSKXGVPYGGILLAAVICLCGVALNAFNPGQAFEIVLSVAALGIIAG
.* : . : .. .
Mb2347c|M.bovis_AF2122/97 FSVVAVGVIVLRVRE-----------PDLPRGFKVPGYPVTPVLSVLACG
Rv2320c|M.tuberculosis_H37Rv FSVVAVGVIVLRVRE-----------PDLPRGFKVPGYPVTPVLSVLACG
MUL_1244|M.ulcerans_Agy99 FIVVSVGVIILRVRE-----------PALPRGFWVPGYPVTPILSILACG
MAV_2087|M.avium_104 FVVVSVGVIVLRVRE-----------PDLPRGFRVPGYPVTPVLSIMACG
TH_0471|M.thermoresistible__bu FALVSAGVIVLRRTR-----------PDLKRGFRVPFVPWLPLAAIAACL
MAB_4090|M.abscessus_ATCC_1997 YLMVTTPLLLRRLGIGGSTWDANLGQTDADGRKLFSLGRCGLPINILAVG
MSMEG_2184|M.smegmatis_MC2_155 YLMVTAPLLYRRFKG----WPAQRNQVDAEGLPLFSLGRFGIVVNVLAVL
Mflv_3084|M.gilvum_PYR-GCK YLMVTGPLLKKRIQG---HWPPP----DLKEGGYFTMGKWGMPVNIVAVI
Mvan_1845|M.vanbaalenii_PYR-1 FQMVVLAALRARLKG-------------WVPSGKYSLGKWGLAVNIAALV
MMAR_2243|M.marinum_M FTLVHLAVTKHFLID-----------QRRRGWRSWALYAAMPAVGVVLTG
MLBr_01304|M.leprae_Br4923 WGTIVLCQLRLHKMAKAG--------IMRRPRFRMPLAPYSGYLTLAFLF
: : . :
Mb2347c|M.bovis_AF2122/97 YILASLHWYTWLAFSGWVAVAVIFYLMWGRHHSALNEEVP----------
Rv2320c|M.tuberculosis_H37Rv YILASLHWYTWLAFSGWVAVAVIFYLMWGRHHSALNEEVP----------
MUL_1244|M.ulcerans_Agy99 YLLYSLHWYTWIAFGGWVGIALIFYLFWGRHHSRLNAPALHDNPTGEER-
MAV_2087|M.avium_104 YILASLHWYTWIAFSGWVLLALIFYFVWGRHHSALNDAAVD--PSGQER-
TH_0471|M.thermoresistible__bu WLMLNLTGLTWVRFLGWMALGLVLYFFYGRHHSMLGRGMTDISARRTG--
MAB_4090|M.abscessus_ATCC_1997 YGAFMILNLSWPRPAVFDPTGEHPYLVWMAPICIIAVLLAGLVAYPRHT-
MSMEG_2184|M.smegmatis_MC2_155 YGAVMIVNLGWPRAEIFNPTGEYPVLQWAGPLSIAATVLLGALCFPRGK-
Mflv_3084|M.gilvum_PYR-GCK WGIGMALNLAWPRAAVY---GEGWYYEWGAFIYIGVILGAGLVWYFVKGR
Mvan_1845|M.vanbaalenii_PYR-1 YGVTAMINMAWPR-----TPDAPWYDNWIVALSAAVVIGIGLVYMVVHPL
MMAR_2243|M.marinum_M WLWTSLSVGAFAIGFAWLGIGTSYLAVLTRGFRKPAPAVDFDADAAPIQT
MLBr_01304|M.leprae_Br4923 AVLVVMAFDKPIGTWTVASLIVIVPALIAGWYSIRKRVMTIARERMGYTG
Mb2347c|M.bovis_AF2122/97 ----------------
Rv2320c|M.tuberculosis_H37Rv ----------------
MUL_1244|M.ulcerans_Agy99 ----------------
MAV_2087|M.avium_104 ----------------
TH_0471|M.thermoresistible__bu ----------------
MAB_4090|M.abscessus_ATCC_1997 ------ASTTEETVR-
MSMEG_2184|M.smegmatis_MC2_155 ------THPKPVTIGA
Mflv_3084|M.gilvum_PYR-GCK NHIGTLKSHAAESLDG
Mvan_1845|M.vanbaalenii_PYR-1 HDKSTAPYADAIPTK-
MMAR_2243|M.marinum_M EIDLTKEGTLQ-----
MLBr_01304|M.leprae_Br4923 PFPAIANPPVKSSD--