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MKRIVFLMAGLTAIVAVAVVLTLIIVNALRTPVNGPVRHYDALFTDASGLIVGNDVRISGVQVGKVEKIH LDGKNARITFNVLTDHPLYQNTTVAIRYQSLVGQRYVEIAQAPTPSAPLAAGTTIPLGQTIPSFDIAKLF NGFRPIFETLDPAQFNRLTENILQLIQGDERGIGPILRDIDAVLKLSVDRQAALQTIITNLGDISKDLGG TSDQLFYLINDLNDVLEPFEKQADEFNRAGADALPVLRRSVSLLRYIENSVDGAQLPLYDVASRTTPGTP TIMAGLSLIPDLVQGMRDALIEEKTAPPTAYECKNGVVKMPGIGEVSFANQDLVVCK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4031 | - | - | 100% (337) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_4567c | - | 2e-42 | 36.73% (245) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_1009c | - | 3e-42 | 32.92% (322) | putative MCE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0605 | mce2B | 8e-31 | 34.07% (273) | MCE-family protein MCE2B |
| M. gilvum PYR-GCK | Mflv_0009 | - | 4e-39 | 30.98% (326) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv0170 | mce1B | 1e-30 | 29.83% (295) | MCE-family protein MCE1B |
| M. leprae Br4923 | MLBr_02590 | mce1B | 3e-30 | 32.10% (271) | putative secreted protein |
| M. marinum M | MMAR_3865 | mce5B | 1e-39 | 35.80% (243) | Mce family protein, Mce5B |
| M. avium 104 | MAV_0103 | - | 6e-44 | 33.03% (330) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_1144 | - | 4e-44 | 32.02% (331) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_3156 | - | 1e-44 | 32.42% (330) | PUTATIVE virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_3797 | mce5B | 6e-39 | 35.39% (243) | Mce family protein, Mce5B |
| M. vanbaalenii PYR-1 | Mvan_0960 | - | 3e-38 | 31.61% (329) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0009|M.gilvum_PYR-GCK -MKYRGPLIGLSLFMIVAITLTWLVYVTLRRDVAGEKVPYSAMFTDVFGL
Mvan_0960|M.vanbaalenii_PYR-1 -MKYRGALVGLSLFMVVAVTLTWLVYVTLRRDVAGSTAPYAAVFTDVFGL
MSMEG_1144|M.smegmatis_MC2_155 -MKIRGALIGLSLFMVVALTLTWMVYVTLRRDVAGRTVPYTAVFTDVFGL
TH_3156|M.thermoresistible__bu -MRSRGALIGLSLFMAVAVVLTWLVYVTLRRDVAGSTVPYSAVFTDVFGL
MMAR_3865|M.marinum_M -MKFRGPLIGLSLFMVVAVALTWMVYVSLRREVAGKTVAYAAVFTDVYGL
MUL_3797|M.ulcerans_Agy99 -MKFRGPLIGLSLFMVVAVALTWMVYVSLRREVAGKTVAYAAVFTDVYGL
MAV_0103|M.avium_104 ---MRGPLIGLSLFMAIAIAVTWMVYATLRRDVAGPTTPYAAMFTDVYGL
Rv0170|M.tuberculosis_H37Rv -MKITGTVVKLGIVSVVLLFFTVMIIVIFGQMRFDRTNGYTAEFSNVSGL
MLBr_02590|M.leprae_Br4923 -MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFTNISGL
Mb0605|M.bovis_AF2122/97 -MKTTGTTIKLGIVWLVLSVFTVMIIVVFGQVRFHHTTGYSAVFTHVSGL
MAB_4031|M.abscessus_ATCC_1997 MKRIVFLMAGLTAIVAVAVVLTLIIVNALRTPVNGPVRHYDALFTDASGL
* . : .* :: : * * *:. **
Mflv_0009|M.gilvum_PYR-GCK REGDDVRMAGVRVGRVEKIELDG--KLAKVSFVVQGDQQVLGTTVASVTY
Mvan_0960|M.vanbaalenii_PYR-1 REGDDVRMAGVRVGRVEKIELQG--DLAKVSFVVQNDQQVLGTTVASVTY
MSMEG_1144|M.smegmatis_MC2_155 REGDDVRMAGVRVGRVEKIELDG--KHAKVSFVVQADQQVFGNTVASVTY
TH_3156|M.thermoresistible__bu REGDDVRMAGVRVGRVERIELDG--KYAKVSFVVQSDQQVLGNTVASVTY
MMAR_3865|M.marinum_M REGDDVRMAGVRVGRVEKIDLEG--KLAKVRFVVQNEQRLFGNTVASVTY
MUL_3797|M.ulcerans_Agy99 REGDGVRMAGVRVGRVEKIDLEG--KLAKVRFVVQNEQRLFGNTVASVTY
MAV_0103|M.avium_104 RVGDDVRMAGVRVGRVEKVELAG--KLAKVSFIVENDQRLYGNTVASVTY
Rv0170|M.tuberculosis_H37Rv RQGQFVRASGVEIGKVKALHLVDGGRRVRVEFNIDRSVPLYQSTTAQIRY
MLBr_02590|M.leprae_Br4923 RTGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTTAQIRY
Mb0605|M.bovis_AF2122/97 RAGQFVRAAGVEVGKVAKVTLIDGDKQVLVDFTVDRSLSLDQATTASIRY
MAB_4031|M.abscessus_ATCC_1997 IVGNDVRISGVQVGKVEKIHLDG--KNARITFNVLTDHPLYQNTTVAIRY
*: ** :**.:*:* : * . . : * : . : *.. : *
Mflv_0009|M.gilvum_PYR-GCK QNIVGQRYLGLTLGS-QGEPVPLPAGSVLPLERSDPSFDVTTLLNGYEPL
Mvan_0960|M.vanbaalenii_PYR-1 QNIVGQRYLGLSLGN-TGDPRPLPAGSVIPLERSEASFDVTTLLNGYEPL
MSMEG_1144|M.smegmatis_MC2_155 QNIVGQRYLGLSLGK-EGDPTLLAAGSVIPLERTDPSFDVGTLLNGYEPL
TH_3156|M.thermoresistible__bu QNIVGQRYLGLSLGN-LGDPHPLPPGATIPVEQTDPSFDVGALLNGYEPL
MMAR_3865|M.marinum_M QNIVGQRYLGLSLGK-KGSPDQLAPGSVIPVQRTEPSFDVTALLNGYEPL
MUL_3797|M.ulcerans_Agy99 QNIVGQRYLGLSLGK-KGSPDQLAPGSVIPVQRTEPSFDVTALLNGYEPL
MAV_0103|M.avium_104 QNIIGQRYLGLSLGE-TGSRTTLSAGSVIPVQQTDPSFDVGKLLNGFEPL
Rv0170|M.tuberculosis_H37Rv SDLIGNRYVELKRGEGKGANDLLPPGGLIPLSRTSPALDLDALIGGFKPV
MLBr_02590|M.leprae_Br4923 LDLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIGGFKPL
Mb0605|M.bovis_AF2122/97 LNLIGDRYLELGRG---HSGQRLAPGATIPLEHTHPALDLDALLGGFRPL
MAB_4031|M.abscessus_ATCC_1997 QSLVGQRYVEIAQAP--TPSAPLAAGTTIPLGQTIPSFDIAKLFNGFRPI
.::*:**: : . :..* :*: :: .::*: *:.*:.*:
Mflv_0009|M.gilvum_PYR-GCK FSLLDPQAADDLTQGVIQSLQGDEASLVALVDQTSQLTESFAGHDEELGA
Mvan_0960|M.vanbaalenii_PYR-1 FSLLNPRDADNLTQGVIQSLQGDEASIVGLVDQTSQLTESLAGRDEELGT
MSMEG_1144|M.smegmatis_MC2_155 FSVLDPKYANNLTEGVIQSLQGDQGSITALIDQTAQLTEAFAGREEELGS
TH_3156|M.thermoresistible__bu FSVLDPKHADNLTKGVIESLQGDEASITALVDQTAQLTEAFAGRDEELGA
MMAR_3865|M.marinum_M FSLLNPRDADNLTKGIIESLQGDTASLATLVSQTSTLTETFAGRDQALGD
MUL_3797|M.ulcerans_Agy99 FSLLNPRDADNLTKGIIESLQGDTASLATLVSQTSTLTETFAGRDQALGD
MAV_0103|M.avium_104 FTLLNPKDADDLTKGVLQSLQGDQASIPLLVEQTSTITKTLSARDQSLGD
Rv0170|M.tuberculosis_H37Rv FRALDPAKVNNIANALITVFQGQGGTINDILDQTAQLTSQIAERDQAIGE
MLBr_02590|M.leprae_Br4923 FRALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERDQAIGE
Mb0605|M.bovis_AF2122/97 FQTLDPDKVNSIASSIITVFQGQGATINDILDQTASLTATLADRDHAIGE
MAB_4031|M.abscessus_ATCC_1997 FETLDPAQFNRLTENILQLIQGDERGIGPILRDIDAVLKLSVDRQAALQT
* *:* : ::. :: :**: : :: : : :: :
Mflv_0009|M.gilvum_PYR-GCK VITDLNTVMSNLAKHNDSMDQVLTETQAAVSIFDAQRQELVDSTGSISRV
Mvan_0960|M.vanbaalenii_PYR-1 VITDLNAVMGNLARHNDSLDQVLTQVQSAVTTFDGQRQELVDSTGSMARV
MSMEG_1144|M.smegmatis_MC2_155 VITDLNAVAANLARHNDDLDHIVSEAQSVVATFEARRPELVESMGSIAKV
TH_3156|M.thermoresistible__bu VITDLNTVVANLARHNDDLDHVIGEARSVVSTFDDRRDQLIDSMGSAAKV
MMAR_3865|M.marinum_M VITNLNKVIYNLAQQNDNLDGVITDTREVVSTLDQRRPELVSSIGSLARV
MUL_3797|M.ulcerans_Agy99 VITNLNKVIYNLAQQNDNLDGVITDTREVVSTLDQRRPELVSSIGSLARV
MAV_0103|M.avium_104 LISSLTRVTDTVARQNDDLDQALNQTRDAVANFDDRRAALQDDVGSIARV
Rv0170|M.tuberculosis_H37Rv VVKNLNIVLDTTVKHRKEFDETVNNLENLITGLRNHSDQLAGGLAHISNG
MLBr_02590|M.leprae_Br4923 VVKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFAHISNA
Mb0605|M.bovis_AF2122/97 VVNNLNTVLATTVKHQTEFDRTVDKLEVLITGLKNRADPLAAAAAHISSA
MAB_4031|M.abscessus_ATCC_1997 IITNLGDISKDLGGTSDQLFYLINDLNDVLEPFEKQADEFNRAGADALPV
::..* : .: : . . : : : : .
Mflv_0009|M.gilvum_PYR-GCK VSRLSTVSDDVYPSLNELIEREPGFAQHLVSIEPQLAFTGANLPLLLKGF
Mvan_0960|M.vanbaalenii_PYR-1 VRQLSTISDEVYPSLNELITREPGFTQHMVSIEPQLAFTGANLPLLLKGF
MSMEG_1144|M.smegmatis_MC2_155 VRQLSTISDEVYPSLSEMVQRQPGFAAHMLGIEPQLAFVGANLPLMLKGF
TH_3156|M.thermoresistible__bu IRQLSAISDEVYQPLNEMVQREPGFAKHMLGIEPQLAFVGANLPLMLKGF
MMAR_3865|M.marinum_M LERLSASANDVYPQLREFIDRQPGATRHILSVEPQVAFFGDNIPLLLKGL
MUL_3797|M.ulcerans_Agy99 LERLSASANDVYPQLREFIDRQPGATRHILSVEPQVAFFGDNIPLLLKGL
MAV_0103|M.avium_104 TRRLSAIADDVDPSLNELITREPGFSKHLVGIEPQLAFTGDNLPLLLKGF
Rv0170|M.tuberculosis_H37Rv AGTVADLLAENRTLVRKAVSYLDAIQQPVIDQRVELDDLLHKTPTALTAL
MLBr_02590|M.leprae_Br4923 AGTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQLEDYLHKLPTVLNQI
Mb0605|M.bovis_AF2122/97 AGTLADLLGADRPLLHSSFGHLEGIQQPLIDELAELDHVLGKLPDAYRII
MAB_4031|M.abscessus_ATCC_1997 LRRSVSLLRYIENSVDGAQLPLYDVASRTTPGTPTIMAGLSLIPDLVQGM
: : * :
Mflv_0009|M.gilvum_PYR-GCK ARIT-SEGAYANAYACDLNATGFFPGLNDVTPIIVDAATPG--------N
Mvan_0960|M.vanbaalenii_PYR-1 ARIT-GEGAYANAYACDLNIQGFFPGLNDVVPIIVDAATPG--------N
MSMEG_1144|M.smegmatis_MC2_155 ARIT-QEGTYANAYLCDLNATAFFPGLNDVTPIIVDAATPG--------N
TH_3156|M.thermoresistible__bu ARVT-GEGTYANAYACNLDGTAFFPGLNDITPIIVAAATPG--------N
MMAR_3865|M.marinum_M TRVG-NRGAYGNAYVCDINAFGFFPGLNDVMPIIVNAATPG--------N
MUL_3797|M.ulcerans_Agy99 TRVG-NRGAYGNAYVCDINAFGFFPGLNDVMPIIVNAATPG--------N
MAV_0103|M.avium_104 ARAV-SEGSYGNAYACDLNATGFFPGLNDITTFIVNAATPGNAYPITTKN
Rv0170|M.tuberculosis_H37Rv GRANGTYGDFQNFYLCDLQIKWNGFQAGGPVRTVKLFSQPT---------
MLBr_02590|M.leprae_Br4923 GRTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQPT---------
Mb0605|M.bovis_AF2122/97 GRAGGIYGDFFNFYLCDISLKVNGLQPGGPVRTVKLFGQPT---------
MAB_4031|M.abscessus_ATCC_1997 RDALIEEKTAPPTAYECKNGVVKMPGIGEVSFANQDLVVCK---------
.
Mflv_0009|M.gilvum_PYR-GCK DAQYSPKCRNMANG
Mvan_0960|M.vanbaalenii_PYR-1 DARYTPKCRNMANG
MSMEG_1144|M.smegmatis_MC2_155 KAQHTPKCRSMANG
TH_3156|M.thermoresistible__bu KARYTPKCRNLANG
MMAR_3865|M.marinum_M QARHTPRCRSMADG
MUL_3797|M.ulcerans_Agy99 QARHTPRCRSMADG
MAV_0103|M.avium_104 LGWHTPRCRNMANG
Rv0170|M.tuberculosis_H37Rv -GRCTPQ-------
MLBr_02590|M.leprae_Br4923 -GRCTPQ-------
Mb0605|M.bovis_AF2122/97 -GRCTPQ-------
MAB_4031|M.abscessus_ATCC_1997 --------------