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MLRVFLVDDHGVFRSGVRAELAGESDIEIVGEAGSVVEAVAGIRSSAPDVVLLDVHMPSGGGVAVINGTI GPVCPVFLALSVSDAAEDVIAVIRAGARGYVTKTISGSELADAVRRVAGGDAVFSPRLAGFVLDSFTGRS NAPEPALDPELDSLTPRELEVLRLLARGYTYREIAEDLVISVKTVETHASNVLRKTQQSNRNALTRWAHT RQLD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3714c | - | - | 100% (215) | two-component LuxR family response regulator |
| M. abscessus ATCC 19977 | MAB_4519c | - | 2e-34 | 40.93% (215) | two-component LuxR family response regulator |
| M. abscessus ATCC 19977 | MAB_3891c | - | 4e-28 | 35.47% (203) | LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 2e-29 | 35.64% (202) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_3579 | - | 1e-31 | 39.72% (214) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3133c | devR | 2e-29 | 35.64% (202) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | MLBr_00773 | mtrA | 9e-08 | 27.65% (170) | putative two-component response regulator |
| M. marinum M | MMAR_3959 | - | 8e-34 | 40.38% (213) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_4114 | - | 1e-32 | 41.31% (213) | response regulator receiver domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3240 | - | 1e-33 | 41.59% (214) | DNA-binding response regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3563 | - | 2e-34 | 40.38% (213) | PUTATIVE DNA-binding response regulator, LuxR family protein |
| M. ulcerans Agy99 | MUL_3814 | - | 2e-33 | 39.91% (213) | two component transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5474 | - | 1e-31 | 39.22% (204) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3157c|M.bovis_AF2122/97 ------MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAEAMARVP
Rv3133c|M.tuberculosis_H37Rv ------MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAEAMARVP
Mvan_5474|M.vanbaalenii_PYR-1 ----MKPIRLVLVDDHAILRQGLRSVLERADDLIVVGEAASESEAVAVVG
MAB_3714c|M.abscessus_ATCC_199 -----MMLRVFLVDDHGVFRSGVRAELAGESDIEIVGEAGSVVEAVAGIR
MMAR_3959|M.marinum_M MSEHESP-TVMVVDDHPIWRDAVARDLS-DDGFAVVATADGVATAQRRAA
MUL_3814|M.ulcerans_Agy99 MSEHESP-TVMVVDDHPIWRDAVARDLS-DDGFAVVATADGVATAQRRAA
MAV_4114|M.avium_104 MTDDATPTTVMVVDDHPIWRDAVARDLA-ESGFAVVATADGVATAQRRAG
Mflv_3579|M.gilvum_PYR-GCK MGIDRT--SVMVVDDHPIWRDAVARDLA-DDGFDVVATADGVASAKRRAA
MSMEG_3240|M.smegmatis_MC2_155 MMTDAAP-TVMVVDDHPIWRDAVARDLA-DDGFDVVATADGVASASRRAA
TH_3563|M.thermoresistible__bu MGEPQQP-TVMVVDDHPIWREAVARDLA-EAGLSVVATADGVAAARRRAA
MLBr_00773|M.leprae_Br4923 --MDIMRQRILVVDDDASLAEMLTIVLR-GEGFDTAVIGDG-TQALTAVR
:.:***. : * : . . . *
Mb3157c|M.bovis_AF2122/97 AARPDVAVLDVRLPDG---NGIELCRDLLSRMPDLRCLILTSYTSDEAML
Rv3133c|M.tuberculosis_H37Rv AARPDVAVLDVRLPDG---NGIELCRDLLSRMPDLRCLILTSYTSDEAML
Mvan_5474|M.vanbaalenii_PYR-1 ATSPDVVLLDLKLSAGSEFEGLTLCAKLSAAHPKLGLLVLTTFLDEDLVV
MAB_3714c|M.abscessus_ATCC_199 SSAPDVVLLDVHMPSG---GGVAVINGTIGPVCPV-FLALSVSDAAEDVI
MMAR_3959|M.marinum_M IVKPDVVVMDMRLADG---DGVQATTEVLKVSPATRVLVLSASDEREDVL
MUL_3814|M.ulcerans_Agy99 IVKPDVVVMDMRLADG---DGVQATTEVLKVSPATRVLVLSTSDEREDVL
MAV_4114|M.avium_104 VVRPDVVVMDMQLPDG---DGAQATAAVLAVSPSSRVLVLSASDERDDVL
Mflv_3579|M.gilvum_PYR-GCK VVRPDVVVMDMRLGDG---DGAQATTEVLAVSPSSRILVLSASDERDDVL
MSMEG_3240|M.smegmatis_MC2_155 VVRPDVVLMDMRLGDG---SGAQATAEVLAVSPRSRVLVLSASDERDDVL
TH_3563|M.thermoresistible__bu AVRPDVVLMDMRLPDG---DGARATAEVRAVSPDSRVLVLSASEERDDVL
MLBr_00773|M.leprae_Br4923 ELRPDLVLLDLMLPGM---NGIDVCR-VLRADSGVPIVMLTAKTDTVDVV
**:.::*: : * : *: ::
Mb3157c|M.bovis_AF2122/97 DAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLRGAA
Rv3133c|M.tuberculosis_H37Rv DAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLRGAA
Mvan_5474|M.vanbaalenii_PYR-1 RAVHAGARGYVVKDVDTTELVRAIRAISAGDSAFDSRSAAAVVRSMSGRS
MAB_3714c|M.abscessus_ATCC_199 AVIRAGARGYVTKTISGSELADAVRRVAGGDAVFSPRLAGFVLDSFTGRS
MMAR_3959|M.marinum_M EAVKAGATGYLVKSASKAELADAVRATAAGRAVFTPSLAGLVLGEYRRIA
MUL_3814|M.ulcerans_Agy99 EAVKTGATGYLVKSASKAELADAVRATAAGRAVFTPSLAGLVLGEYRRIA
MAV_4114|M.avium_104 QAVKAGAAGYLVKSASKAELAQAVTDTAAGRAVFTPSLAGLVLGEYRRIA
Mflv_3579|M.gilvum_PYR-GCK EAVKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEFRRIE
MSMEG_3240|M.smegmatis_MC2_155 QAVKAGATGYLVKSASRTELADAVRATAEGRAVFTPGLAGLVLGEYRRIA
TH_3563|M.thermoresistible__bu EAVKAGATGYLVKSASKTELVDAVHATAQGRAVFTPGLAGLVLGEYRRIS
MLBr_00773|M.leprae_Br4923 LGLESGADDYIMKPFKPKELVARVRARLRRNDDEPAEMLSIADVDIDVPA
: :** .*: * . ** : . .
Mb3157c|M.bovis_AF2122/97 EKQD-----PLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLA
Rv3133c|M.tuberculosis_H37Rv EKQD-----PLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLA
Mvan_5474|M.vanbaalenii_PYR-1 ESR--------AQLTDREVEVLRLLAAG---------LSNNKIGERLYIS
MAB_3714c|M.abscessus_ATCC_199 NAPEPALDPELDSLTPRELEVLRLLARG---------YTYREIAEDLVIS
MMAR_3959|M.marinum_M QT-ADSSQ-DRPSLTERETEILRYVAKG---------LSAKQIAEKLSLS
MUL_3814|M.ulcerans_Agy99 QT-ADSSQ-DRPSLTERETEILRYVAKG---------LSAKQIAEKLSLS
MAV_4114|M.avium_104 QS-KDDGP-TRPRLTDRETEVLRYVAKG---------LSAKQIAEKLSLS
Mflv_3579|M.gilvum_PYR-GCK QS-SPAGA-DGPTLTERETEILRYVAKG---------LTAKQIASRLSLS
MSMEG_3240|M.smegmatis_MC2_155 QQPAQEGP-ATPTLTERETEILRYVAKG---------LTAKQIAARLSLS
TH_3563|M.thermoresistible__bu RQ-PGAGP-DAPRLTERETEILRYVAKG---------LTAKQIAAQLSLS
MLBr_00773|M.leprae_Br4923 HKVTRNGE--HISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPAD
. ** * :* :: . .
Mb3157c|M.bovis_AF2122/97 EKTVKNYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP
Rv3133c|M.tuberculosis_H37Rv EKTVKNYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP
Mvan_5474|M.vanbaalenii_PYR-1 ATTAKFHVSNIMRKLEVSRRAEAVYAAS--KRGLI-----
MAB_3714c|M.abscessus_ATCC_199 VKTVETHASNVLRKTQQSNRNALTRWAH--TRQLD-----
MMAR_3959|M.marinum_M HRTVENHVQATFRKLQVANRVELTRYAIEHGLDK------
MUL_3814|M.ulcerans_Agy99 HRTVENHVQATFRKLQLANRVELTRYAIEHGLDK------
MAV_4114|M.avium_104 HRTVENHVQATFRKLQVANRVELARYAIEHGLDEEP----
Mflv_3579|M.gilvum_PYR-GCK HRTVENHVQATFRKLQVGNRVELARYAIEHGLDE------
MSMEG_3240|M.smegmatis_MC2_155 HRTVENHVQATFRKLQVANRVELARYAIEHGLDE------
TH_3563|M.thermoresistible__bu HRTVENHVQATFRKLQVANRVELARYAIEHGLDE------
MLBr_00773|M.leprae_Br4923 TRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP--
.: :.. * . . :