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SSDIPVESKGLKGGALGLLSSVVVGLASTAPAYSLAATLGLIVASGGALLAGVKAPAIVLISFIPMYLIA VAYQELNKAEPDCGTTFTWASRTFGPIVGWLGGWGIIAADVICLANLAQVAGAYSFTFVGDLGWSAASGL ADSVLWSTVAGVIWIVIMTYICYRGIEVSARLQYWLLTVEVVVLIAFAVVALIKVYTHNAESYSLLPSLS WFWPGGMDFGTVIAPAVLTTIFIYWGWDTAVACNEESDDPGRTPGRAAVISTFLLLATYALVSVAAVAFA GVGTEGVGLGNQENAADVFKAIGPELFGDSFVGHLGMLLLSASILTSASACTQTTILPTARTTLSMGVYK ALPDSFASIHRTYLTPSTSTIAMGAISIVFYVLFTAISTNLLTALIGSVGLMIAFYYGLTGFACAWFYRK RLTTSFRDLMMRGVMPLAGGATLTVVFIYGLIQYAKPNWLIDDDGNNVTVFGVGAVAVVGVGALVLGVVL MMLWRVAAPPFFQGQTLPRRSADLVLAPAAATTHFGLPDAVEAQQTVIAGDLSNLPEGEVAVNPQTGEEF TKD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3331c | - | - | 100% (564) | putative amino acid permease |
| M. abscessus ATCC 19977 | MAB_4323 | - | e-105 | 41.34% (508) | putative amino acid transporter |
| M. abscessus ATCC 19977 | MAB_4206 | - | e-102 | 39.44% (502) | putative amino acid transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2022c | - | 9e-23 | 26.99% (489) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_4853 | - | 1e-116 | 44.47% (488) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv1999c | - | 9e-23 | 26.99% (489) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3554 | - | 0.0 | 73.40% (564) | hypothetical protein MMAR_3554 |
| M. avium 104 | MAV_2087 | - | 1e-13 | 22.78% (395) | amino acid transporter |
| M. smegmatis MC2 155 | MSMEG_1625 | - | 1e-109 | 40.55% (508) | amino acid transporter, putative |
| M. thermoresistible (build 8) | TH_3126 | - | 2e-10 | 26.22% (267) | PUTATIVE putative amino acid permease-associated region |
| M. ulcerans Agy99 | MUL_2787 | - | 0.0 | 72.87% (564) | hypothetical protein MUL_2787 |
| M. vanbaalenii PYR-1 | Mvan_1574 | - | 1e-122 | 45.83% (504) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3554|M.marinum_M MGHLDADKKTSHQPIEGDCVSQGEATSVAVEGKGLKGGAVGLLSSVVIGT
MUL_2787|M.ulcerans_Agy99 MGHLDADKKTNHQPIEGDCVSQGEATSVAVEGKGLKGGAVGLLSSVVIGT
MAB_3331c|M.abscessus_ATCC_199 -----------------------MSSDIPVESKGLKGGALGLLSSVVVGL
Mflv_4853|M.gilvum_PYR-GCK ---------------------------------------------MVIGL
Mvan_1574|M.vanbaalenii_PYR-1 ---MAITDEPAVP---------------AVGGKGLQAGALGLVGNVVIGL
MSMEG_1625|M.smegmatis_MC2_155 ---MTRSDPQSDPESDPHHALEIVEQSAGLRGKGLAAGKVGTFSGAILGI
Mb2022c|M.bovis_AF2122/97 ----------------------MRRPLDPRDIPDELRRRLGLLDAVVIGL
Rv1999c|M.tuberculosis_H37Rv ----------------------MRRPLDPRDIPDELRRRLGLLDAVVIGL
TH_3126|M.thermoresistible__bu -----------------------------------LPRRLGTLDAVTIGL
MAV_2087|M.avium_104 ---------------------------MAPGTADHLRRGIGTFQLTMFGV
.*
MMAR_3554|M.marinum_M ASTAPAYSLAATLGLIVASRGELLCGVKAPAIVLLSFIPMYMIAVAYQEL
MUL_2787|M.ulcerans_Agy99 ASTAPAYSLAATLGLIVASRGELLCGVKAPAIVLLSFIPMYMIAVAYQEL
MAB_3331c|M.abscessus_ATCC_199 ASTAPAYSLAATLGLIVASGGALLAGVKAPAIVLISFIPMYLIAVAYQEL
Mflv_4853|M.gilvum_PYR-GCK GAVAPAYSLAATLGYVVLN-----VQEKAPSMFVLAFIPMLLVAFAYKEL
Mvan_1574|M.vanbaalenii_PYR-1 GAVAPAYSLAATLGYVVLN-----VQEKAPAMFVLAFIPMLLVAFAYKEL
MSMEG_1625|M.smegmatis_MC2_155 SSVAPGYTLTASIGLIVAA-----VGLKMPAIFIAGFIPMFLTAYAYREL
Mb2022c|M.bovis_AF2122/97 GSMIGAGIFAALAPAAYAA------GSGLLLGLAVAAVVAYCNAISSARL
Rv1999c|M.tuberculosis_H37Rv GSMIGAGIFAALAPAAYAA------GSGLLLGLAVAAVVAYCNAISSARL
TH_3126|M.thermoresistible__bu GAMIGAGIFVALGPAAAAA------GPWLLAGLGIAAAVAYCNATASARL
MAV_2087|M.avium_104 GSTIGTGIFFVMSQAVPEA------GPAVIVSFLLAGVAAGLAAVCYAEL
.: : . . . * . .*
MMAR_3554|M.marinum_M NKAEPDCGTTFTWASRAFGPVTGWLGGWGIIAADVIVMANLAQIAGAYSF
MUL_2787|M.ulcerans_Agy99 NKAEPDCGTTFTWASRAFGPVTGWLGGWGIIAADVIVMANLAQIAGAYSF
MAB_3331c|M.abscessus_ATCC_199 NKAEPDCGTTFTWASRTFGPIVGWLGGWGIIAADVICLANLAQVAGAYSF
Mflv_4853|M.gilvum_PYR-GCK SQDTPDCGTTFTWATKAFGPWIGWIGGWGLAVSAIIVLANVSEIAAIYLY
Mvan_1574|M.vanbaalenii_PYR-1 SQDTPDCGTTFTWGTKAFGPWIGWIGGWGLAVSAIIVLANVSEIAAIYLY
MSMEG_1625|M.smegmatis_MC2_155 NSRAPDCGASFTWSTKAFGPYVGWMCGWGMVIATIIVLSNLAAIAVEFFY
Mb2022c|M.bovis_AF2122/97 AARYPASGGTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALTVGFYVW
Rv1999c|M.tuberculosis_H37Rv AARYPASGGTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALTVGFYVW
TH_3126|M.thermoresistible__bu AARYPQSGGTYVYGRERLGAFWGYTAGFSFVVGKTASCAAMALTIGFYLW
MAV_2087|M.avium_104 ASAVPVSGSSYSYAYTTLGEVVAMGVAACLLLEYGVATAAVSVNWSGYLN
* .* :: :. :* . . : : :: :
MMAR_3554|M.marinum_M TFVG-EL-----GWQSASNLAHSALWSTVAGVAWIVVMTYICYRGTDVSA
MUL_2787|M.ulcerans_Agy99 TFVG-EL-----GWQSASNLAHSTLWSTVAGVAWIVVMTCICYRGTDVSA
MAB_3331c|M.abscessus_ATCC_199 TFVG-DL-----GWSAASGLADSVLWSTVAGVIWIVIMTYICYRGIEVSA
Mflv_4853|M.gilvum_PYR-GCK NFLG------------LTSLAESVPATVALGCFFIIAMTLVSARGIVVSE
Mvan_1574|M.vanbaalenii_PYR-1 NFLG------------LDSLAESVPATVALGCFFIISMTLVSARGIVVSE
MSMEG_1625|M.smegmatis_MC2_155 LFVARIL-----NTPEIADLADNKLVNILTTLVFIALATWVSSRGITTSE
Mb2022c|M.bovis_AF2122/97 PAQA-----------------------HAVAVAVVVALTAVNYAGIQKSA
Rv1999c|M.tuberculosis_H37Rv PAQA-----------------------HAVAVAVVVALTAVNYAGIQKSA
TH_3126|M.thermoresistible__bu PGHA-----------------------HAIAVAAVVALTALTYLGIEKSA
MAV_2087|M.avium_104 KLLSNVVGFQLPHALSAAPWDAQPGYVNLPAVMLIGMCALLLIRGASESA
. : : : * *
MMAR_3554|M.marinum_M RMQYVLLSVELVVLVALAAVALARVYTNHGDVGSLRPSLSWLWP-SGLDF
MUL_2787|M.ulcerans_Agy99 RMQYVLLSVELVVLVALAAVALARVYTNHGDVGSLRPSLSWLWP-SGLDF
MAB_3331c|M.abscessus_ATCC_199 RLQYWLLTVEVVVLIAFAVVALIKVYTHNAESYSLLPSLSWFWP-GGMDF
Mflv_4853|M.gilvum_PYR-GCK RVQNVLIAIQFGVLITVSIIALVRVFSGTAGAQAVMPEVSWLWP-SGLDV
Mvan_1574|M.vanbaalenii_PYR-1 RVQNVLIAIQFGVLITVSVIALIRVFTGTAGAQAISPQLSWLWP-SGLDV
MSMEG_1625|M.smegmatis_MC2_155 HVQYVLVGFQMTVLLAFAITAVIHVGAGNA-PEGLAFDLDWFNPFTNLAF
Mb2022c|M.bovis_AF2122/97 WLTRSIVAVVLVVLTAVVVAAYG---SGAADPARLDIGVDAHVW------
Rv1999c|M.tuberculosis_H37Rv WLTRSIVAVVLVVLTAVVVAAYG---SGAADPARLDIGVDAHVW------
TH_3126|M.thermoresistible__bu LLTRLVVAGVLGVLTAVVVLVLG---FGAPAGRVAGGGTDIGAG------
MAV_2087|M.avium_104 KVNAIMVMVKLGVLVVFGILAFT-----AFDMHHLDDFAPFGVA------
: :: . ** .. .
MMAR_3554|M.marinum_M GTQMAPALLITIFIYWGFDTAVACNEETDDPGRTPGRAAVISTFLLLATY
MUL_2787|M.ulcerans_Agy99 GTQMAPALLITIFIYWGFDTAVACNDETDDPGRTLGRAAVISTFLLLATY
MAB_3331c|M.abscessus_ATCC_199 GTVIAPAVLTTIFIYWGWDTAVACNEESDDPGRTPGRAAVISTFLLLATY
Mflv_4853|M.gilvum_PYR-GCK S-SIAAAVILCIFIYWGWDACLAVGEETKDPGKTPGIAALITTVILVCTY
Mvan_1574|M.vanbaalenii_PYR-1 S-SIAAAVILCIFIYWGWDACLAVGEETKDPGRTPGIAALVTTVILVCTY
MSMEG_1625|M.smegmatis_MC2_155 G-AFVIGVTGSIFAFWGWDTCLTLGEESKDPTKVPGRAGLLCVTTILLTY
Mb2022c|M.bovis_AF2122/97 --GMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVY
Rv1999c|M.tuberculosis_H37Rv --GMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVY
TH_3126|M.thermoresistible__bu --AVLQSAALLFFAFAGYARIATLGEEVRDPARTIRRAIPLALGITLTVY
MAV_2087|M.avium_104 --GVGTAAGTIFFSYIGLDAVSTAGDEVTNPQKTMPRALIAALLTVTGVY
. . :* : * : .:* :* :. * .*
MMAR_3554|M.marinum_M AVVTVASIAFAGVGVDGIGLGNPDNSNDVFAAVGPALFGDGVLGKIGLLL
MUL_2787|M.ulcerans_Agy99 AVVTVASIAFAGVGVDGIGLGNPDNSNDVFAAVGPALFGDGVLGKIGLLL
MAB_3331c|M.abscessus_ATCC_199 ALVSVAAVAFAGVGTEGVGLGNQENAADVFKAIGPELFGDSFVGHLGMLL
Mflv_4853|M.gilvum_PYR-GCK VLVAYALQSFAGFSEVGIGLNNPNNTDDVLTVLG-----EPVAGAIAASA
Mvan_1574|M.vanbaalenii_PYR-1 VLVAFALQSFAGFSEVGIGLNNPNNTDDVLTVLG-----KPVAGAIAASA
MSMEG_1625|M.smegmatis_MC2_155 LLVAVAVMMYAGVGETGLGLGNPENSENVFGALA-----DPVLGSWGGPL
Mb2022c|M.bovis_AF2122/97 ALVAVAVIAVLGPQRLARAAAPLSEAMRVAGVNW------------LIPV
Rv1999c|M.tuberculosis_H37Rv ALVAVAVIAVLGPQRLARAAAPLSEAMRVAGVNW------------LIPV
TH_3126|M.thermoresistible__bu GAVTAAVLVALGSAGLARSPAPVADAVTAAXX------------------
MAV_2087|M.avium_104 VFVALAALGTQPWQDFGGQQEAGLATILDHVTHG----------SWASTI
*: * . :
MMAR_3554|M.marinum_M LSASILTSASASTQTTILPTARTTLSMAVYKALPASFAKIHPRYLTPTVS
MUL_2787|M.ulcerans_Agy99 LSASILTSASASTQTTILPTARTTLSMAVYKALPASFAKIHPRYLTPTVS
MAB_3331c|M.abscessus_ATCC_199 LSASILTSASACTQTTILPTARTTLSMGVYKALPDSFASIHRTYLTPSTS
Mflv_4853|M.gilvum_PYR-GCK LLLTVSVSALSSTQTTILPTARGTLSMAVYEAIPRRFASVHPRYMTPAFG
Mvan_1574|M.vanbaalenii_PYR-1 LLLTVSVSALSSTQTTILPTARGTLSMAVYEAIPKRFANVHPRYMTPAFG
MSMEG_1625|M.smegmatis_MC2_155 LFLAVLASSVASLQTTFLPAARAMLAMGAYGAFPKRFSHVHPRFLVPSFS
Mb2022c|M.bovis_AF2122/97 VQIGAAVAALGSLLALILGVSRTTLAMARDRHLPRWLAAVHPRFKVPFRA
Rv1999c|M.tuberculosis_H37Rv VQIGAAVAALGSLLALILGVSRTTLAMARDRHLPRWLAAVHPRFKVPFRA
TH_3126|M.thermoresistible__bu ----------------------------HGRQQP----------------
MAV_2087|M.avium_104 LAAGAVISIFSVTLVTMYGITRILFAMGRDGLLPPRFARVNPRTMTPVNN
*
MMAR_3554|M.marinum_M TIAMGAVSILFYVLFTLVSRNLLSALIGSVGLVIAFYYGLTGYACAHYYR
MUL_2787|M.ulcerans_Agy99 TIAMGAVSILFYVLFTLVSRNLLSALIGSVGLVIAFYYGLTGYACAHYYR
MAB_3331c|M.abscessus_ATCC_199 TIAMGAISIVFYVLFTAISTNLLTALIGSVGLMIAFYYGLTGFACAWFYR
Mflv_4853|M.gilvum_PYR-GCK TIVMGISALFFYLVLKMLSENALLDSVASLGLAVAFYYGITAFACVWYFR
Mvan_1574|M.vanbaalenii_PYR-1 TIVMGLSALFFYLVLKALSENALLDSVASLGLAVAFYYGITAFACVWYFR
MSMEG_1625|M.smegmatis_MC2_155 TLIAGIVTGVFYTVVSLLSEYALLDTIAALGIMICWYYGITAFACIWYFR
Mb2022c|M.bovis_AF2122/97 ELVVGAV------VAALAATADIRGAIGFSSFGVLVYYAIANASALTLG-
Rv1999c|M.tuberculosis_H37Rv ELVVGAV------VAALAATADIRGAIGFSSFGVLVYYAIANASALTLG-
TH_3126|M.thermoresistible__bu -------------FGELPGAEEV---------------------------
MAV_2087|M.avium_104 TVIVAVAAATLAAFIPLQNLADMVSIGTLTAFVVVSVGVIVLRVREPDLP
. :
MMAR_3554|M.marinum_M ATLTKSLRNFVMRGVVPLTGGVVLTVVFIFGLIEYAKRDWLVEN-GHNVT
MUL_2787|M.ulcerans_Agy99 ATLTKSLRNFVMRGVVPLTGGVVLTVVFIFGLIEYAKRDWLVEN-GHNVT
MAB_3331c|M.abscessus_ATCC_199 KRLTTSFRDLMMRGVMPLAGGATLTVVFIYGLIQYAKPNWLIDDDGNNVT
Mflv_4853|M.gilvum_PYR-GCK RTLFSSARNLFFRGVFPLLGGLSMLAAFAISAKDMIQP-----DYG-HTA
Mvan_1574|M.vanbaalenii_PYR-1 RTLFESTRNLFFRGVFPLLGGLSMLAAFTISAKDMIQP-----DYG-YTA
MSMEG_1625|M.smegmatis_MC2_155 RELFTDAHNIVFKFLFPLIGGLVLAAVFGFSLKESMDP-----ENGSGAE
Mb2022c|M.bovis_AF2122/97 ---LDEGRPRRLIPLVGLIGCVVLAFALPLSSVAAGAA------------
Rv1999c|M.tuberculosis_H37Rv ---LDEGRPRRLIPLVGLIGCVVLAFALPLSSVAAGAA------------
TH_3126|M.thermoresistible__bu ----DRGHPQRIPDARRHPGHVEHRSSP--TTCAPRP-------------
MAV_2087|M.avium_104 RGFRVPGYP-VTPVLSIMACGYILASLHWYTWIAFSG-------------
MMAR_3554|M.marinum_M IFGFGAVAVVGVGSMLLGVVVMLIWWAI-SPGFFRGRTLRRHSADLLLEP
MUL_2787|M.ulcerans_Agy99 IFGFGAVAVVGVGSMLLGVVVMLIWWAI-SPGFFRGRTLRRHSADLLLEP
MAB_3331c|M.abscessus_ATCC_199 VFGVGAVAVVGVGALVLGVVLMMLWRVA-APPFFQGQTLPRRSADLVLAP
Mflv_4853|M.gilvum_PYR-GCK FGSIGGVFVLGVGMLVLGIPLMLACFAFGTKRFFRGETLNADTAVKVPDT
Mvan_1574|M.vanbaalenii_PYR-1 FGPVGGVFVLGVGMLVLGIPLMLACFAFGTKRFFRGETLNADTEVKVPDT
MSMEG_1625|M.smegmatis_MC2_155 LGGIGLVFYIGFGILLLGAVLMLVMRTR-SPEFFRGETLSRNTPVIPG--
Mb2022c|M.bovis_AF2122/97 --------VLGVGVAAYGVRRIITRRARQTDSGDTQRSGHPSAT------
Rv1999c|M.tuberculosis_H37Rv --------VLGVGVAAYGVRRIITRRARQTDSGDTQRSGHPSAT------
TH_3126|M.thermoresistible__bu -------------------LTWRTTWAPMPDPQPVTTTRRPS--------
MAV_2087|M.avium_104 --------------WVLLALIFYFVWGRHHSALNDAAVDPSGQER-----
MMAR_3554|M.marinum_M AVSPPAHLALPDSGD-MQTVIAADLSNLPAGETAVNPQTGQHLTKDTSGA
MUL_2787|M.ulcerans_Agy99 AVSPPAHLALPDSGD-MQTVIAADLSNLPAGETAVNPQTGQHLTKDTSGA
MAB_3331c|M.abscessus_ATCC_199 AAAT-THFGLPDAVEAQQTVIAGDLSNLPEGEVAVNPQTGEEFTKD----
Mflv_4853|M.gilvum_PYR-GCK F-------------------------------------------------
Mvan_1574|M.vanbaalenii_PYR-1 F-------------------------------------------------
MSMEG_1625|M.smegmatis_MC2_155 --------------------------------------------------
Mb2022c|M.bovis_AF2122/97 --------------------------------------------------
Rv1999c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3126|M.thermoresistible__bu --------------------------------------------------
MAV_2087|M.avium_104 --------------------------------------------------
MMAR_3554|M.marinum_M S
MUL_2787|M.ulcerans_Agy99 S
MAB_3331c|M.abscessus_ATCC_199 -
Mflv_4853|M.gilvum_PYR-GCK -
Mvan_1574|M.vanbaalenii_PYR-1 -
MSMEG_1625|M.smegmatis_MC2_155 -
Mb2022c|M.bovis_AF2122/97 -
Rv1999c|M.tuberculosis_H37Rv -
TH_3126|M.thermoresistible__bu -
MAV_2087|M.avium_104 -