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VSQRSDALSVGGKGLAGGQIGTFSGAVLGISSVAPGYTLSASLGLLVAAVGLKMPAILIAGFLPMFLTAY AYRELNAKNPDAGASFTWSSRAFGPYVGWMAGWGQVVACIIVLSNLAAVAVQFFYLFIAQVSHHLAIADL ASNKPVNIATTLAIMLVATYVACRGITTGERVQYALVGFQMLMLFGFAGAALWKVGTGAAPGHLSFDADW FNPFSGLTIGAFVVGVTGSVFAFWGWDTCLTLGEESKDPDRVPGRAGLLSVTSILLTYLLVAVALTMYAG VGTTGLGLGNPANEENIFGALADPVLGPFFGPFLSLAVLASAVAGLQTTFLPLARVMLAMGVYGAVPRRF AEISPRFLVPRFSTIVSSAVTAVFYTVVTVLSEHTLTDTIAALGIMICWYYGITAFACIWEFRHTLFRGV RNVVFRFLCPLLGGAMLLVIFAISIRESMDPANGSGSSIGGIGLVFFLGFGILALGVVLMLVQRAVAPRF FTENTWHTGSEKVIAETLVPECPEPAKDLRTV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4323 | - | - | 100% (522) | putative amino acid transporter |
| M. abscessus ATCC 19977 | MAB_4206 | - | 0.0 | 67.82% (491) | putative amino acid transporter |
| M. abscessus ATCC 19977 | MAB_3331c | - | e-105 | 41.34% (508) | putative amino acid permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2022c | - | 3e-19 | 25.68% (475) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_4853 | - | 1e-109 | 41.82% (483) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv1999c | - | 3e-19 | 25.68% (475) | integral membrane protein |
| M. leprae Br4923 | MLBr_01305 | ansP2 | 8e-07 | 21.91% (493) | putative L-asparagine permease |
| M. marinum M | MMAR_2609 | - | 0.0 | 65.24% (489) | hypothetical protein MMAR_2609 |
| M. avium 104 | MAV_2087 | - | 2e-13 | 23.94% (401) | amino acid transporter |
| M. smegmatis MC2 155 | MSMEG_1625 | - | 0.0 | 71.49% (484) | amino acid transporter, putative |
| M. thermoresistible (build 8) | TH_0471 | - | 8e-15 | 25.82% (368) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_2787 | - | 1e-102 | 39.54% (526) | hypothetical protein MUL_2787 |
| M. vanbaalenii PYR-1 | Mvan_1574 | - | 1e-113 | 42.32% (501) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2087|M.avium_104 ---------------------------MAPGTADH------LRRGIGTFQ
TH_0471|M.thermoresistible__bu ------------------MTDRLRVKSVEQSIADTDEPDSRLRKDLSWWD
Mb2022c|M.bovis_AF2122/97 ----------------------------MRRPLDPRDIPDELRRRLGLLD
Rv1999c|M.tuberculosis_H37Rv ----------------------------MRRPLDPRDIPDELRRRLGLLD
MMAR_2609|M.marinum_M MTDTPAPPLFARGPKGNKLKVQPIVPQLSNTAAEGVVSKGLAKGAVGTVS
MSMEG_1625|M.smegmatis_MC2_155 MTRSDP----QSDPESDPHHALEIVEQS-----AGLRGKGLAAGKVGTFS
MAB_4323|M.abscessus_ATCC_1997 MS-----------QRSDALSVG---------------GKGLAGGQIGTFS
Mflv_4853|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1574|M.vanbaalenii_PYR-1 ------------------------MAITDEPAVPAVGGKGLQAGALGLVG
MUL_2787|M.ulcerans_Agy99 MGHLDA------DKKTNHQPIEGDCVSQGEATSVAVEGKGLKGGAVGLLS
MLBr_01305|M.leprae_Br4923 ----------------MATLAESPEPKSGASRAGVLGEEAGYHKGLKPRQ
MAV_2087|M.avium_104 LTMFGVGSTIGTG-IFFVMSQAVP-----EAGPAVIVSFLLAGVAAGLAA
TH_0471|M.thermoresistible__bu LTVFGVSVVIGAG-IFTVTASTAGN----ITGPAISVSFIIAAIACGLAA
Mb2022c|M.bovis_AF2122/97 AVVIGLGSMIGAG-IFAALAPAAY-----AAGSGLLLGLAVAAVVAYCNA
Rv1999c|M.tuberculosis_H37Rv AVVIGLGSMIGAG-IFAALAPAAY-----AAGSGLLLGLAVAAVVAYCNA
MMAR_2609|M.marinum_M GAILGIACVAPGYTLTASIGLIVAA-----VGLKMPAIFVFGFIPMFLTA
MSMEG_1625|M.smegmatis_MC2_155 GAILGISSVAPGYTLTASIGLIVAA-----VGLKMPAIFIAGFIPMFLTA
MAB_4323|M.abscessus_ATCC_1997 GAVLGISSVAPGYTLSASLGLLVAA-----VGLKMPAILIAGFLPMFLTA
Mflv_4853|M.gilvum_PYR-GCK -MVIGLGAVAPAYSLAATLGYVVLN-----VQEKAPSMFVLAFIPMLLVA
Mvan_1574|M.vanbaalenii_PYR-1 NVVIGLGAVAPAYSLAATLGYVVLN-----VQEKAPAMFVLAFIPMLLVA
MUL_2787|M.ulcerans_Agy99 SVVIGTASTAPAYSLAATLGLIVASRGELLCGVKAPAIVLLSFIPMYMIA
MLBr_01305|M.leprae_Br4923 LQMIGIGGAIGTGLFLGAGGRLAKA------GPGLFLVYAVCGVFVFLIL
::* . : . . :
MAV_2087|M.avium_104 VCYAELASAVPVSGSSYSYAYTTLGEVVAMGVAACLLLEYGVATAAVSVN
TH_0471|M.thermoresistible__bu LCYAEFASTVPVAGSAYTFSYATFGEFVAWIIGWDLILEFSVAAAVVAKG
Mb2022c|M.bovis_AF2122/97 ISSARLAARYPASGGTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALT
Rv1999c|M.tuberculosis_H37Rv ISSARLAARYPASGGTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALT
MMAR_2609|M.marinum_M FAYRELNADTPDCGASFTWSTKAFGPYVGWMCGWGMVIATVIVLSNLAAV
MSMEG_1625|M.smegmatis_MC2_155 YAYRELNSRAPDCGASFTWSTKAFGPYVGWMCGWGMVIATIIVLSNLAAI
MAB_4323|M.abscessus_ATCC_1997 YAYRELNAKNPDAGASFTWSSRAFGPYVGWMAGWGQVVACIIVLSNLAAV
Mflv_4853|M.gilvum_PYR-GCK FAYKELSQDTPDCGTTFTWATKAFGPWIGWIGGWGLAVSAIIVLANVSEI
Mvan_1574|M.vanbaalenii_PYR-1 FAYKELSQDTPDCGTTFTWGTKAFGPWIGWIGGWGLAVSAIIVLANVSEI
MUL_2787|M.ulcerans_Agy99 VAYQELNKAEPDCGTTFTWASRAFGPVTGWLGGWGIIAADVIVMANLAQI
MLBr_01305|M.leprae_Br4923 RALGELVLHRPSSGSFVSYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTA
. .: * .* :. :* . . :
MAV_2087|M.avium_104 WSGYLNKLLSNVVGFQLPHALSAAPWDAQPGYVNLPAVMLIGMCALLLIR
TH_0471|M.thermoresistible__bu WSSYLGEVFE----------FAGATTRLGPITLDWGALLIIGFVTVLLAT
Mb2022c|M.bovis_AF2122/97 VG-----------------------FYVWPAQAHAVAVAVVVALTAVNYA
Rv1999c|M.tuberculosis_H37Rv VG-----------------------FYVWPAQAHAVAVAVVVALTAVNYA
MMAR_2609|M.marinum_M AVQFFYLLIAGLFDSP-----GIASLAANRWVDIASTLVFIAGATWVSSR
MSMEG_1625|M.smegmatis_MC2_155 AVEFFYLFVARILNTP-----EIADLADNKLVNILTTLVFIALATWVSSR
MAB_4323|M.abscessus_ATCC_1997 AVQFFYLFIAQVSHHL-----AIADLASNKPVNIATTLAIMLVATYVACR
Mflv_4853|M.gilvum_PYR-GCK AAIYLYNFLG------------LTSLAESVPATVALGCFFIIAMTLVSAR
Mvan_1574|M.vanbaalenii_PYR-1 AAIYLYNFLG------------LDSLAESVPATVALGCFFIISMTLVSAR
MUL_2787|M.ulcerans_Agy99 AGAYSFTFVGELGWQ------SASNLAHSTLWSTVAGVAWIVVMTCICYR
MLBr_01305|M.leprae_Br4923 IATYLHR-----------------WTIFTALPQWTLALLALAVVLVMNLI
: :
MAV_2087|M.avium_104 GASESAKVNAIMVMVKLGVLVVFGILAFTAFDMHHLDDFAP---------
TH_0471|M.thermoresistible__bu GTKLSANVSLAITVIKVGVVLLVVIVGAFFIKAANYTPFIPPAEAGGEAG
Mb2022c|M.bovis_AF2122/97 GIQKSAWLTRSIVAVVLVVLTAVVVAAYGSGAADPARLDIG---------
Rv1999c|M.tuberculosis_H37Rv GIQKSAWLTRSIVAVVLVVLTAVVVAAYGSGAADPARLDIG---------
MMAR_2609|M.marinum_M GIQTSERVQGLLVIFQMTVILGFGVVAIIGAVRGHG-PANLSFDFNWFDP
MSMEG_1625|M.smegmatis_MC2_155 GITTSEHVQYVLVGFQMTVLLAFAITAVIHVGAGNA-PEGLAFDLDWFNP
MAB_4323|M.abscessus_ATCC_1997 GITTGERVQYALVGFQMLMLFGFAGAALWKVGTGAA-PGHLSFDADWFNP
Mflv_4853|M.gilvum_PYR-GCK GIVVSERVQNVLIAIQFGVLITVSIIALVRVFSGTAGAQAVMPEVSWLWP
Mvan_1574|M.vanbaalenii_PYR-1 GIVVSERVQNVLIAIQFGVLITVSVIALIRVFTGTAGAQAISPQLSWLWP
MUL_2787|M.ulcerans_Agy99 GTDVSARMQYVLLSVELVVLVALAAVALARVYTNHGDVGSLRPSLSWLWP
MLBr_01305|M.leprae_Br4923 SVEWFGELEFWAALIKVCALMAFLVVGTIFLGGRYPVDGHNTGLSLWTSH
. : . . : . .
MAV_2087|M.avium_104 ------------------FGVAG-VGTAAGTIFFSYIGLDAVSTAGDEVT
TH_0471|M.thermoresistible__bu RSLDQSLFSLITGAEGSSYGWYG-LLAGASIVFFAFIGFDIIATTAEETK
Mb2022c|M.bovis_AF2122/97 ----------------VDAHVWG-MLQAAGLLFFAFAGYARIATLGEEVR
Rv1999c|M.tuberculosis_H37Rv ----------------VDAHVWG-MLQAAGLLFFAFAGYARIATLGEEVR
MMAR_2609|M.marinum_M F---------------SGLAMGA-FVIGVTGSIFSFWGWDTCLTLGEECT
MSMEG_1625|M.smegmatis_MC2_155 F---------------TNLAFGA-FVIGVTGSIFAFWGWDTCLTLGEESK
MAB_4323|M.abscessus_ATCC_1997 F---------------SGLTIGA-FVVGVTGSVFAFWGWDTCLTLGEESK
Mflv_4853|M.gilvum_PYR-GCK ----------------SGLDVSS-IAAAVILCIFIYWGWDACLAVGEETK
Mvan_1574|M.vanbaalenii_PYR-1 ----------------SGLDVSS-IAAAVILCIFIYWGWDACLAVGEETK
MUL_2787|M.ulcerans_Agy99 ----------------SGLDFGTQMAPALLITIFIYWGFDTAVACNDETD
MLBr_01305|M.leprae_Br4923 GG-------------LFPTGVAP-LIVVSSGVMFAYAAVELVGTAAGETV
. .* : . : *
MAV_2087|M.avium_104 NPQKTMPRALIAALLTVTGVYVFVALAALGTQPWQD----FGGQQE-AGL
TH_0471|M.thermoresistible__bu NPQRDVARGIMATLGIVTVLYVAVSLVLTGMVHYTE----LRAAGENANL
Mb2022c|M.bovis_AF2122/97 DPARTIPRAIPLALGITLAVYALVAVAVIAVLGPQR----LARAAA--PL
Rv1999c|M.tuberculosis_H37Rv DPARTIPRAIPLALGITLAVYALVAVAVIAVLGPQR----LARAAA--PL
MMAR_2609|M.marinum_M DPKKVPGRAGVLCVVSILLTYLLVSVAMMMYAGVGSQGLGLGNPDNSENV
MSMEG_1625|M.smegmatis_MC2_155 DPTKVPGRAGLLCVTTILLTYLLVAVAVMMYAGVGETGLGLGNPENSENV
MAB_4323|M.abscessus_ATCC_1997 DPDRVPGRAGLLSVTSILLTYLLVAVALTMYAGVGTTGLGLGNPANEENI
Mflv_4853|M.gilvum_PYR-GCK DPGKTPGIAALITTVILVCTYVLVAYALQSFAGFSEVGIGLNNPNNTDDV
Mvan_1574|M.vanbaalenii_PYR-1 DPGRTPGIAALVTTVILVCTYVLVAFALQSFAGFSEVGIGLNNPNNTDDV
MUL_2787|M.ulcerans_Agy99 DPGRTLGRAAVISTFLLLATYAVVTVASIAFAGVGVDGIGLGNPDNSNDV
MLBr_01305|M.leprae_Br4923 EPKKIMPRAINSVIARIAIFYVGSVILLALLLPYSAFKASESPFVTFFSK
:* : . *
MAV_2087|M.avium_104 ATILD-----HVTHGSWASTILAAGAVISIFSVTLVTMYGITRILFAMGR
TH_0471|M.thermoresistible__bu ATAFA-----ANGID-WAAKVISIGALAGLTTVVIVLVLGQTRVLFAMSR
Mb2022c|M.bovis_AF2122/97 SEAMR-----VAGVN-WLIPVVQIGAAVAALGSLLALILGVSRTTLAMAR
Rv1999c|M.tuberculosis_H37Rv SEAMR-----VAGVN-WLIPVVQIGAAVAALGSLLALILGVSRTTLAMAR
MMAR_2609|M.marinum_M FGALA-----RPVLGPWGSQLLFLGILASTLSSLQTTFLPASRCMLAMGA
MSMEG_1625|M.smegmatis_MC2_155 FGALA-----DPVLGSWGGPLLFLAVLASSVASLQTTFLPAARAMLAMGA
MAB_4323|M.abscessus_ATCC_1997 FGALA-----DPVLGPFFGPFLSLAVLASAVAGLQTTFLPLARVMLAMGV
Mflv_4853|M.gilvum_PYR-GCK LTVLG-----EPVAGAIAASALLLTVSVSALSSTQTTILPTARGTLSMAV
Mvan_1574|M.vanbaalenii_PYR-1 LTVLG-----KPVAGAIAASALLLTVSVSALSSTQTTILPTARGTLSMAV
MUL_2787|M.ulcerans_Agy99 FAAVGPALFGDGVLGKIGLLLLSASILTSASASTQTTILPTARTTLSMAV
MLBr_01305|M.leprae_Br4923 VGFYG------------AGDLMNIVVLTAALSSLNAGLYATGRVMHSIAI
: . . . * ::.
MAV_2087|M.avium_104 DGLLPPRFARVNPRTMTPVNNTVIVAVAAATLAAFIPLQN------LADM
TH_0471|M.thermoresistible__bu DGLLPRPLSKTGPR-GTPVRITVLVGALVAIAASVFPVGN------LEEM
Mb2022c|M.bovis_AF2122/97 DRHLPRWLAAVHPRFKVPFRAELVVGAVVAALAATADIRG------AIGF
Rv1999c|M.tuberculosis_H37Rv DRHLPRWLAAVHPRFKVPFRAELVVGAVVAALAATADIRG------AIGF
MMAR_2609|M.marinum_M YRAFPQRFSAVSSRFQVPLFSTIAAAIASGAFYTLARLLSE--RTLLDTI
MSMEG_1625|M.smegmatis_MC2_155 YGAFPKRFSHVHPRFLVPSFSTLIAGIVTGVFYTVVSLLSE--YALLDTI
MAB_4323|M.abscessus_ATCC_1997 YGAVPRRFAEISPRFLVPRFSTIVSSAVTAVFYTVVTVLSE--HTLTDTI
Mflv_4853|M.gilvum_PYR-GCK YEAIPRRFASVHPRYMTPAFGTIVMGISALFFYLVLKMLSE--NALLDSV
Mvan_1574|M.vanbaalenii_PYR-1 YEAIPKRFANVHPRYMTPAFGTIVMGLSALFFYLVLKALSE--NALLDSV
MUL_2787|M.ulcerans_Agy99 YKALPASFAKIHPRYLTPTVSTIAMGAVSILFYVLFTLVSR--NLLSALI
MLBr_01305|M.leprae_Br4923 NGSGPK-FTARMSKNGVPYGGILLAAVICLCGVALNAFNPGQAFEIVLSV
* :: .: .* : . .
MAV_2087|M.avium_104 VSIGTLTAFVVVSVGVIVLRVREPD--LPRGFR-VPGYPVTPVLSIMACG
TH_0471|M.thermoresistible__bu VNIGTLFAFALVSAGVIVLRRTRPD--LKRGFR-VPFVPWLPLAAIAACL
Mb2022c|M.bovis_AF2122/97 SSFGVLVYYAIANASALTLGLDEGR--PRR------LIPLVGLIGCVVLA
Rv1999c|M.tuberculosis_H37Rv SSFGVLVYYAIANASALTLGLDEGR--PRR------LIPLVGLIGCVVLA
MMAR_2609|M.marinum_M AALGMLVCWYYGITAFACMWYFRKE--LFTSLRNVVFKFLCPLLGGMMLL
MSMEG_1625|M.smegmatis_MC2_155 AALGIMICWYYGITAFACIWYFRRE--LFTDAHNIVFKFLFPLIGGLVLA
MAB_4323|M.abscessus_ATCC_1997 AALGIMICWYYGITAFACIWEFRHT--LFRGVRNVVFRFLCPLLGGAMLL
Mflv_4853|M.gilvum_PYR-GCK ASLGLAVAFYYGITAFACVWYFRRT--LFSSARNLFFRGVFPLLGGLSML
Mvan_1574|M.vanbaalenii_PYR-1 ASLGLAVAFYYGITAFACVWYFRRT--LFESTRNLFFRGVFPLLGGLSML
MUL_2787|M.ulcerans_Agy99 GSVGLVIAFYYGLTGYACAHYYRAT--LTKSLRNFVMRGVVPLTGGVVLT
MLBr_01305|M.leprae_Br4923 AALGIIAGWGTIVLCQLRLHKMAKAGIMRRPRFRMPLAPYSGYLTLAFLF
.* :
MAV_2087|M.avium_104 YILAS--------------------LHWYTWIAFSGWVLLALIFYFVWGR
TH_0471|M.thermoresistible__bu WLMLN--------------------LTGLTWVRFLGWMALGLVLYFFYGR
Mb2022c|M.bovis_AF2122/97 FALPL--------------------SSVAAGAAVLGVGVAAYGVRRIITR
Rv1999c|M.tuberculosis_H37Rv FALPL--------------------SSVAAGAAVLGVGVAAYGVRRIITR
MMAR_2609|M.marinum_M LVFVVSVRES-----MDPRHGSGASIAGVGLVFYLGFGILSLGAVLMVVM
MSMEG_1625|M.smegmatis_MC2_155 AVFGFSLKES-----MDPENGSGAELGGIGLVFYIGFGILLLGAVLMLVM
MAB_4323|M.abscessus_ATCC_1997 VIFAISIRES-----MDPANGSGSSIGGIGLVFFLGFGILALGVVLMLVQ
Mflv_4853|M.gilvum_PYR-GCK AAFAISAKD------MIQPDYGHTAFGSIGGVFVLGVGMLVLGIPLMLAC
Mvan_1574|M.vanbaalenii_PYR-1 AAFTISAKD------MIQPDYGYTAFGPVGGVFVLGVGMLVLGIPLMLAC
MUL_2787|M.ulcerans_Agy99 VVFIFGLIEYAKRDWLVENGHNVTIFG-FGAVAVVGVGSMLLGVVVMLIW
MLBr_01305|M.leprae_Br4923 AVLVVMAFDKP--------------IGTWTVASLIVIVPALIAGWYSIRK
:
MAV_2087|M.avium_104 HHSALNDAAVDPSGQER---------------------------------
TH_0471|M.thermoresistible__bu HHSMLGRGMTDISARRTG--------------------------------
Mb2022c|M.bovis_AF2122/97 RARQTDSGDTQRSGHPSAT-------------------------------
Rv1999c|M.tuberculosis_H37Rv RARQTDSGDTQRSGHPSAT-------------------------------
MMAR_2609|M.marinum_M RVRQPG-FFLGHTLTPSTPALTDDAAIATASHPDAGPDQHH---------
MSMEG_1625|M.smegmatis_MC2_155 RTRSPE-FFRGETLSRNTPVIPG---------------------------
MAB_4323|M.abscessus_ATCC_1997 RAVAPR-FFTENTWHTGSEKVIAETLVPECPEPAKDLRTV----------
Mflv_4853|M.gilvum_PYR-GCK FAFGTKRFFRGETLN-------ADTAVKVPDTF-----------------
Mvan_1574|M.vanbaalenii_PYR-1 FAFGTKRFFRGETLN-------ADTEVKVPDTF-----------------
MUL_2787|M.ulcerans_Agy99 WAISPG-FFRGRTLRRHSADLLLEPAVSPPAHLALPDSGDMQTVIAADLS
MLBr_01305|M.leprae_Br4923 RVMTIARERMGYTGPFPAIANPPVQPSERSHSQNP---------------
:
MAV_2087|M.avium_104 -------------------------
TH_0471|M.thermoresistible__bu -------------------------
Mb2022c|M.bovis_AF2122/97 -------------------------
Rv1999c|M.tuberculosis_H37Rv -------------------------
MMAR_2609|M.marinum_M -------------------------
MSMEG_1625|M.smegmatis_MC2_155 -------------------------
MAB_4323|M.abscessus_ATCC_1997 -------------------------
Mflv_4853|M.gilvum_PYR-GCK -------------------------
Mvan_1574|M.vanbaalenii_PYR-1 -------------------------
MUL_2787|M.ulcerans_Agy99 NLPAGETAVNPQTGQHLTKDTSGAS
MLBr_01305|M.leprae_Br4923 -------------------------