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VSVPSSWINGRPVATHGDTHRVINPATGEAVADLKLATTADVDAAVAAARAAGPAWASSTPVDRSSVLAK LAAVLSANADTLVADEVAQTGKPVRLASEFDVPGSIDNVEFFAGAARHLEGKATAEYSADHTSSIRREAA GVVATITPWNYPLQMAVWKVLPALAAGCTVVIKPSELTPLTTLTLARLAAEAGLPEGVLNVVTGRGDDVG YALASHPDVDLVTFTGSTAVGRKVMAAAAVHGHRTQLELGGKAPFVVFDDADMDAAIAGAVAGAIINSGQ DCTAATRALVARDLYDDFVAGVGEVMSKVVVGDPLDPDTDIGPLISAAHRAKVSSIVDRAPAQGGRIVTG ATAPDLPGSFYRPTLIADVAETSEVYRDEIFGPVLTVRPFTDDDDALRQANDTAYGLAASAWTRDVYRAQ RASREIRAGCVWINDHIPIISEMPHGGFGASGFGKDMSDYSLEEYLTVKHVMSDITGTADKDWHRTIFAK R
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3328 | - | - | 100% (491) | gamma-aminobutyraldehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4203 | - | e-110 | 46.24% (452) | putative aldehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4484 | - | 9e-89 | 40.57% (456) | aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2883c | aldC | 6e-91 | 41.63% (454) | aldehyde dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4860 | - | 0.0 | 80.04% (491) | gamma-aminobutyraldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv2858c | aldC | 6e-91 | 41.63% (454) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 4e-72 | 37.03% (451) | succinic semialdehyde dehydrogenase |
| M. marinum M | MMAR_3556 | - | 0.0 | 79.02% (491) | aldehyde dehydrogenase NAD dependent |
| M. avium 104 | MAV_2101 | - | 9e-95 | 40.87% (460) | aldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1665 | - | 0.0 | 81.26% (491) | gamma-aminobutyraldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3902 | - | 5e-86 | 39.83% (482) | PUTATIVE putative 5-carboxymethyl-2-hydroxymuconate |
| M. ulcerans Agy99 | MUL_2789 | - | 0.0 | 77.80% (491) | gamma-aminobutyraldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1572 | - | 0.0 | 81.89% (486) | gamma-aminobutyraldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4860|M.gilvum_PYR-GCK -------------MTVASSWIDGA-PVKTGGAQHTVINPATGESVAEFAL
Mvan_1572|M.vanbaalenii_PYR-1 --------------MLAGSWIDGA-PVNTRGPVHQVINPATGAPVAEYAL
MSMEG_1665|M.smegmatis_MC2_155 -----------MAVKVASSWINGA-SVETSGETHQIIDPATGKSVSEYNL
MAB_3328|M.abscessus_ATCC_1997 -------------MSVPSSWINGR-PVATHGDTHRVINPATGEAVADLKL
MMAR_3556|M.marinum_M ---------MTTTVSVAGSWINGA-AHSTGGRQHAVINPATQETIAELAL
MUL_2789|M.ulcerans_Agy99 ---------MTTTVSVAGSWINGA-AHSTGGRQHAVINPATQETIAELAL
Mb2883c|M.bovis_AF2122/97 -----------------------------MSTTQ-LINPATEEVLASVDH
Rv2858c|M.tuberculosis_H37Rv -----------------------------MSTTQ-LINPATEEVLASVDH
MAV_2101|M.avium_104 -----------------------------MSTTIPVFNPSTEEQIAEVPD
TH_3902|M.thermoresistible__bu LRANRFQPKDNTVTWKYDLYIDGKWDTGTSGRALTVVNPATEETIGTVPD
MLBr_02573|M.leprae_Br4923 -------------------------------MSIATINPATGETVKTFTP
.:*:* :
Mflv_4860|M.gilvum_PYR-GCK AQPGDVDRAVVSARAALPG--WKGATPAERSAVLAKLAKLADDATADLVA
Mvan_1572|M.vanbaalenii_PYR-1 AQPADVDAAVASARAALGG--WATATPAERSAVLAKLAKLADEATADLVA
MSMEG_1665|M.smegmatis_MC2_155 ATAADVDTAVAAARAAFPA--WAGATPAERSAVLAKLAKLADEHAEQFVA
MAB_3328|M.abscessus_ATCC_1997 ATTADVDAAVAAARAAGPA--WASSTPVDRSSVLAKLAAVLSANADTLVA
MMAR_3556|M.marinum_M ATPADVDRAVVAARRALPQ--WAGVTPAERSAVLAKLADLLEQRAPELIA
MUL_2789|M.ulcerans_Agy99 ATPADVDHAVVAARRALPQ--WAGVTTAERSAVLAELADLLEQRAPELIA
Mb2883c|M.bovis_AF2122/97 TDANAVDDAVQRARAAQRR--WARLAPAQRAAGLRAFAAAVQAHLDELAA
Rv2858c|M.tuberculosis_H37Rv TDANAVDDAVQRARAAQRR--WARLAPAQRAAGLRAFAAAVQAHLDELAA
MAV_2101|M.avium_104 SDQAAVDAAVARARETFESGVWRKAPASHRANVLFRAARIIEERKDELAA
TH_3902|M.thermoresistible__bu ASLDDIRRAIAAARTAFDEGPWPCMTPLERAAVIRRIAEVLQRRRSELVD
MLBr_02573|M.leprae_Br4923 TTQDEVEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQSAA
: : *: * : . .*: * .
Mflv_4860|M.gilvum_PYR-GCK EEVSQTGKPVRLATEFDVPGSVDNIDFFAGAARHLEGKASAEYSGD----
Mvan_1572|M.vanbaalenii_PYR-1 EEVSQTGKPVRLATEFDVPGSVDNIDFFAGAARHLEGKASGEYSAD----
MSMEG_1665|M.smegmatis_MC2_155 EEVSQTGKPVRLATEFDVPGSVDNIDFFAGAARHLEGKATAEYSGD----
MAB_3328|M.abscessus_ATCC_1997 DEVAQTGKPVRLASEFDVPGSIDNVEFFAGAARHLEGKATAEYSAD----
MMAR_3556|M.marinum_M EEVCQTGKPLRLAEEFDVPGSVDNIRFFAGAARRLPGQATAEYSAD----
MUL_2789|M.ulcerans_Agy99 EEVCQTGKPLRLAEEFDVPGSVDNIRFFAGAARRLPGQATAEYSAD----
Mb2883c|M.bovis_AF2122/97 LEVANSGHP-IVSAEWEAGHVRDVLAFYAASPERLSGRQIPVAG------
Rv2858c|M.tuberculosis_H37Rv LEVANSGHP-IVSAEWEAGHVRDVLAFYAASPERLSGRQIPVAG------
MAV_2101|M.avium_104 LESQDNGMN-LTAAGHIIPVSVDMLKYYAGWVGKIHGESANLVSDGLL--
TH_3902|M.thermoresistible__bu LVRAETGSPQWIVEMLQVGVPLRVCADVADRVLPQFRFVEPMLPSFDLRP
MLBr_02573|M.leprae_Br4923 LMTLEMGKTLQSAKDEAMKCAKG-FRYYAEKAETLLADEPAEAAAVG---
: * *
Mflv_4860|M.gilvum_PYR-GCK HTSSIRR-----EAVGVVATITPWNYPLQMAVWKVIPALAAGCSVVIKPA
Mvan_1572|M.vanbaalenii_PYR-1 HTSSIRR-----EAVGVVATITPWNYPLQMAVWKVLPALAAGCSVVIKPA
MSMEG_1665|M.smegmatis_MC2_155 HTSSIRR-----EAVGVVATITPWNYPLQMAVWKVIPALAAGCAVVIKPA
MAB_3328|M.abscessus_ATCC_1997 HTSSIRR-----EAAGVVATITPWNYPLQMAVWKVLPALAAGCTVVIKPS
MMAR_3556|M.marinum_M HTSSIRR-----EAIGVVATITPWNYPLQMAVWKVMPALAAGCTVVIKPS
MUL_2789|M.ulcerans_Agy99 HTSSIRR-----EAIGVVATITPWNYPLQMAVWKVMPALAAGCTVVIKPS
Mb2883c|M.bovis_AF2122/97 GVDVTFN-----EPMGVVGVITPWNFPMVIASWAIAPALAAGNAVLVKPA
Rv2858c|M.tuberculosis_H37Rv GVDVTFN-----EPMGVVGVITPWNFPMVIASWAIAPALAAGNAVLVKPA
MAV_2101|M.avium_104 GTWETYHTFTQLEPVGVVGLIIPWNGPFFVAMLKVAPALAAGCSAVLKPA
TH_3902|M.thermoresistible__bu GQGIISK-----EPIGVAALITPFNFPLFLNVMKLAPALAAGCTVVLKPS
MLBr_02573|M.leprae_Br4923 ASKALAR----YQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHA
. :. **. : *:* *: *** ** ::* :
Mflv_4860|M.gilvum_PYR-GCK EITPLTTLTLARLASEAGLPDGVLNVVTGSGADVGAALAGHADVDMVTFT
Mvan_1572|M.vanbaalenii_PYR-1 EITPLTTLTLARLAAEAGLPAGVFNVVTGSGADVGTALAGHADVDMVTFT
MSMEG_1665|M.smegmatis_MC2_155 EITPLTTLTLARLASEAGLPDGVFNVVTGSGAEVGTALAGHRDVDVVTFT
MAB_3328|M.abscessus_ATCC_1997 ELTPLTTLTLARLAAEAGLPEGVLNVVTGRGDDVGYALASHPDVDLVTFT
MMAR_3556|M.marinum_M ELTPLTTLTLARLAAEAGLPDGVLNVVTGLGADVGAALAAHPGVDLVTFT
MUL_2789|M.ulcerans_Agy99 ELTPLTTLTLARLAAEAGLPDGVLNVVTGLGADVGAALAAHPGVDLVTFT
Mb2883c|M.bovis_AF2122/97 ELTPLTTMRLGELAVEAGLDEDLLQVLPGKGTVVGERFVTHPDIRKIVFT
Rv2858c|M.tuberculosis_H37Rv ELTPLTTMRLGELAVEAGLDEDLLQVLPGKGTVVGERFVTHPDIRKIVFT
MAV_2101|M.avium_104 EETPLTALKLEEIFREAGLPDGVLNVITGYGETTGAALTAHPDVDKISFT
TH_3902|M.thermoresistible__bu PLTPLEALVLGEVADEVGLPPGVLNIVTG-GAEESAELTTNPMVDLVSFT
MLBr_02573|M.leprae_Br4923 SNVPQCALYLADVIARGGFPEDCFQTLLISANGVEAILR-DPRVAAATLT
.* :: * : . *: . :: : . : . : :*
Mflv_4860|M.gilvum_PYR-GCK GSTPVGRRVMLAAAAHGHRTQLELGGKAPFVVFDDADLDAAIQGAVAGAL
Mvan_1572|M.vanbaalenii_PYR-1 GSTPVGRKVMLAAAAHGHRTQLELGGKAPFVVFDDADLDAAIQGAVAGAL
MSMEG_1665|M.smegmatis_MC2_155 GSTAVGRKVMASAAVHGHRTQLELGGKAPFVVFSDADLDAAVQGAVAGAL
MAB_3328|M.abscessus_ATCC_1997 GSTAVGRKVMAAAAVHGHRTQLELGGKAPFVVFDDADMDAAIAGAVAGAI
MMAR_3556|M.marinum_M GSTAVGRKVMAAAATHGRRTQLELGGKAPFVVFDDADLDAAIQGAVAGAL
MUL_2789|M.ulcerans_Agy99 GSTAVGRKVMAAAATHGRRTQLELGGKAPFVVFDDADLDAAIQGAVAGAV
Mb2883c|M.bovis_AF2122/97 GSTEVGKRVMAGAAAQVKRVTLELGGKSANIVFHDCDLERAATTAPAGVF
Rv2858c|M.tuberculosis_H37Rv GSTEVGKRVMAGAAAQVKRVTLELGGKSANIVFHDCDLERAATTAPAGVF
MAV_2101|M.avium_104 GSTEVGRLIVKAAAGNLKRLTLELGGKSPLIMFDDANLDKAIMGAGMGLL
TH_3902|M.thermoresistible__bu GSDTVGRQVMNQASATLKKVVLELGGKSANVIFADADLDAAAAHVVGEFT
MLBr_02573|M.leprae_Br4923 GSEPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRV
** .*: : *. : *****. . ::: ..::: * .
Mflv_4860|M.gilvum_PYR-GCK INTGQDCTAATRAIVAEGLYDDFVAGVAEVMSKVVIGDPADPDTDLGPLI
Mvan_1572|M.vanbaalenii_PYR-1 INTGQDCTAATRAIVARDLYDDFVAGVAEVMSNIVVGDPGDPDTDLGPLI
MSMEG_1665|M.smegmatis_MC2_155 INTGQDCTAATRAIVARELYDDFVAGVAEVMGKIVVGDPHDPDTDLGPLI
MAB_3328|M.abscessus_ATCC_1997 INSGQDCTAATRALVARDLYDDFVAGVGEVMSKVVVGDPLDPDTDIGPLI
MMAR_3556|M.marinum_M INSGQDCTAATRAIVARELYHDFVAGVADVMSTVVIGDPMDPDTDIGPLI
MUL_2789|M.ulcerans_Agy99 INSGQDCTAATRAIVARELCHDFVAGVADVMSTVVIGDPMDPDTDIGPLI
Mb2883c|M.bovis_AF2122/97 DNAGQDCCARSRILVQRSVYDRFMELLEPAVHSIVVGDPGSRATEMGPLV
Rv2858c|M.tuberculosis_H37Rv DNAGQDCCARSRILVQRSVYDRFMELLEPAVHSIVVGDPGSRATEMGPLV
MAV_2101|M.avium_104 AGSGQNCSCTSRIYVQRGIYDQVVEGLAEFAMMLPMGGSDDPNSVLGPLI
TH_3902|M.thermoresistible__bu LHAGQGCSLLTRTLVEESIHDELVDWVNKQLAALKVGDPADPSVMMGPLI
MLBr_02573|M.leprae_Br4923 QNNGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLA
**.* .* . : . .: . : :*.. . :***
Mflv_4860|M.gilvum_PYR-GCK SAVHREKVAGMVERAPGEGGRVVTGGVAPD--GPGSFYRPTLIADVAESS
Mvan_1572|M.vanbaalenii_PYR-1 TLAHRAKVAGMVERAPGEGGRIVTGGVAPD--GPGSFYRPTLIADVSEQS
MSMEG_1665|M.smegmatis_MC2_155 SYAHRDKVAGMVARAPQQGGRVVTGGEAPD--LPGAFYRPTLIADVDESS
MAB_3328|M.abscessus_ATCC_1997 SAAHRAKVSSIVDRAPAQGGRIVTGATAPD--LPGSFYRPTLIADVAETS
MMAR_3556|M.marinum_M SLAHRDRVADIVAKAPAQGARIVVGGRIPD--LAGAFYLPTLLADVGEQS
MUL_2789|M.ulcerans_Agy99 SLAHRDRVADILAKAPAQGARIVVGGRIPD--LAGAFYLPTLLADVGEQS
Mb2883c|M.bovis_AF2122/97 SRAHRDKVAGYVPD----DAPVAFRGTAPA--GRGFWFPPTVLTPKRGD-
Rv2858c|M.tuberculosis_H37Rv SRAHRDKVAGYVPD----DAPVAFRGTAPA--GRGFWFPPTVLTPKRGD-
MAV_2101|M.avium_104 SEKQRQRVEGIVNDGVAAGAKVITGGKPMD--RKGYFYEATIITNTTPDM
TH_3902|M.thermoresistible__bu SEAQRNRVEGYIKAGVDEGAEIAFGGGRPSHLERGYFVEPTLFTGVRNEM
MLBr_02573|M.leprae_Br4923 TESGRAQVEQQVDAAAAAGAVIRCGGKRPD--RPGWFYPPTVITDITKDM
: * :* : .. : . * : .*:::
Mflv_4860|M.gilvum_PYR-GCK EVWRDEIFGPVLTVRSFTDDDDAIRQANDTKYGLAASAWTRDVYRAQRAS
Mvan_1572|M.vanbaalenii_PYR-1 EVWRDEIFGPVLAVRSFTDDDDALRQANDTAYGLAASAWTRDVYRAQRAS
MSMEG_1665|M.smegmatis_MC2_155 EVYRDEIFGPVLTVRSFTDDDDALRQANDTEYGLAASAWTRDVYRAQRAS
MAB_3328|M.abscessus_ATCC_1997 EVYRDEIFGPVLTVRPFTDDDDALRQANDTAYGLAASAWTRDVYRAQRAS
MMAR_3556|M.marinum_M QAYREEIFGPVLTVRAHDGDDDALRQANDTDYGLAASAWTRDVYRAQRAS
MUL_2789|M.ulcerans_Agy99 QAYREEIFGPVLTVRAHDGDDDALRQANDTDYGLAASAWTRDVYRAQRAS
Mb2883c|M.bovis_AF2122/97 RTVTDEIFGPVVVVLTFDDEADAISLANDTAYGLSGSIWTDDLSRALRVA
Rv2858c|M.tuberculosis_H37Rv RTVTDEIFGPVVVVLTFDDEADAISLANDTAYGLSGSIWTDDLSRALRVA
MAV_2101|M.avium_104 RLIREEIFGPVGCVIPFDDEDEVIAAANDTHYGLAGAIWTENLSRAHRVV
TH_3902|M.thermoresistible__bu KIAQEEIFGPVGVVIPFTSEHEAVRLANDSDFGLGGGVWSTDVERALRVA
MLBr_02573|M.leprae_Br4923 ALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFI
:*:**** * . :.: ** : :**.. *: : . :
Mflv_4860|M.gilvum_PYR-GCK REIHAGCVWIN-DHIPIISEMPHGGFGASGFGKDMSQYSLEEYLSIKHVM
Mvan_1572|M.vanbaalenii_PYR-1 REIHAGCVWIN-DHIPIISEMPHGGFGASGFGKDMSQYSLEEYLSIKHVM
MSMEG_1665|M.smegmatis_MC2_155 REINAGCVWIN-DHIPIISEMPHGGVGASGFGKDMSDYSFEEYLTIKHVM
MAB_3328|M.abscessus_ATCC_1997 REIRAGCVWIN-DHIPIISEMPHGGFGASGFGKDMSDYSLEEYLTVKHVM
MMAR_3556|M.marinum_M REISAGCVWIN-DHIPIVSEMPHGGVAASGFGKDMSEYSFEEYLTIKHVM
MUL_2789|M.ulcerans_Agy99 REISAGCVWIN-DHIPIVSEMPHGGVAASGFGNDMSEYSFDEYLTIKHVM
Mb2883c|M.bovis_AF2122/97 RAVESGNLSVN-SHSSVRFNTPFGGFKQSGVGRELGPDAPLQFTETKNVF
Rv2858c|M.tuberculosis_H37Rv RAVESGNLSVN-SHSSVRFNTPFGGFKQSGVGRELGPDAPLQFTETKNVF
MAV_2101|M.avium_104 NELRAGQIWVN-SALAADPSMPISGHKQSGWGGERGRKGIEAYFNTKAVY
TH_3902|M.thermoresistible__bu QRIRTGMVAINGGGGSMGKTGPFGGFKASGLGREWGEWGLDEFLEMKQII
MLBr_02573|M.leprae_Br4923 DNIVAGQVFIN-GMTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVW
: :* : :* . * .* ** * : . . : * :
Mflv_4860|M.gilvum_PYR-GCK SDITSAVDKDWHRTIFTKR-
Mvan_1572|M.vanbaalenii_PYR-1 SDITGVADKTWHRTIFTKR-
MSMEG_1665|M.smegmatis_MC2_155 SDITGVAEKEWHRTIFNKR-
MAB_3328|M.abscessus_ATCC_1997 SDITGTADKDWHRTIFAKR-
MMAR_3556|M.marinum_M SDITGVAEKPWHRTIFSTRI
MUL_2789|M.ulcerans_Agy99 SDITGVAEKPWHRTIFSTRI
Mb2883c|M.bovis_AF2122/97 IAVGEEM-------------
Rv2858c|M.tuberculosis_H37Rv IAVGEEM-------------
MAV_2101|M.avium_104 IGL-----------------
TH_3902|M.thermoresistible__bu WPIAGG--------------
MLBr_02573|M.leprae_Br4923 IA------------------