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DWDELYRGEAVYAPGDPGWNIGEMQPELAALHRQGRFESPILDAGCGIGSTSLALAGHGYQVVGLDLSSG AIEKAKKAAEPLALDVVFDTADLTSDIGYNDHFNTVIDGLVFHCLPAQIRGDYVRSLARSLKPGGRFFAL VFATEAFPPNAEFGPRPFTEQQLRDIVGRHLVVDEVRRARAWVNVPGQLPEGFEYRNVTIGSDGRAQLPA WLVSAHRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4799c | - | - | 100% (219) | hypothetical protein MAB_4799c |
| M. abscessus ATCC 19977 | MAB_0961c | - | 1e-44 | 42.92% (219) | hypothetical protein MAB_0961c |
| M. abscessus ATCC 19977 | MAB_0393 | - | 2e-41 | 44.09% (220) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3725 | - | 2e-40 | 41.67% (228) | hypothetical protein Mb3725 |
| M. gilvum PYR-GCK | Mflv_1324 | - | 3e-45 | 43.50% (223) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3699 | - | 2e-40 | 41.67% (228) | hypothetical protein Rv3699 |
| M. leprae Br4923 | MLBr_01723 | - | 1e-06 | 37.38% (107) | hypothetical protein MLBr_01723 |
| M. marinum M | MMAR_5210 | - | 1e-41 | 42.98% (228) | hypothetical protein MMAR_5210 |
| M. avium 104 | MAV_0404 | - | 6e-46 | 44.55% (220) | thiopurine S-methyltransferase (tpmt) superfamily protein |
| M. smegmatis MC2 155 | MSMEG_6235 | - | 3e-49 | 47.11% (225) | thiopurine S-methyltransferase (tpmt) superfamily protein |
| M. thermoresistible (build 8) | TH_1722 | - | 4e-51 | 47.75% (222) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0662 | - | 3e-35 | 42.49% (193) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_5471 | - | 4e-45 | 43.50% (223) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6235|M.smegmatis_MC2_155 ----MGVMT------SHVLDWDGAYRGDT-GFQG----------PPPWNI
TH_1722|M.thermoresistible__bu ----MATEDPGTGDPTDTIDWDSVYRQEAPGFDG----------PPPWNI
Mb3725|M.bovis_AF2122/97 -------MT------DEVMDWDSAYREQG-AFEG----------PPPWNI
Rv3699|M.tuberculosis_H37Rv -------MT------DEVMDWDSAYREQG-AFEG----------PPPWNI
MMAR_5210|M.marinum_M -------MT------SPVMDWDDAYQQQG-AFEG----------PPPWNI
MAV_0404|M.avium_104 ------MSS------DQVMDWDSAYREQA-HFEG----------PPPWNI
Mflv_1324|M.gilvum_PYR-GCK -------MA-------EVMDWDSAYRGEG-EFEG----------EPPWNI
Mvan_5471|M.vanbaalenii_PYR-1 ----MAHMT-------DVMDWDSAYRGEG-DFEG----------EPPWNI
MUL_0662|M.ulcerans_Agy99 -------MT-----ESLDLQFATAYRGESAEFGAGI--------RPPWSL
MAB_4799c|M.abscessus_ATCC_199 ------------------MDWDELYRGEAVYAPG----------DPGWNI
MLBr_01723|M.leprae_Br4923 MTRSTEISANAVPNPHATAEQVAAARKDSKLAQVLYHDWEAENYDEKWSI
: : : *.:
MSMEG_6235|M.smegmatis_MC2_155 GEPQ-------PELAALHRAGRFRSD----VLDAGCGHAELSLALAADGY
TH_1722|M.thermoresistible__bu GEPQ-------PELAALHRAGAFRSD----VLDAGCGHAEISMALAADGY
Mb3725|M.bovis_AF2122/97 GEPQ-------PELATLIAAGKVRSD----VLDAGCGYAELSLALAADGY
Rv3699|M.tuberculosis_H37Rv GEPQ-------PELATLIAAGKVRSD----VLDAGCGYAELSLALAADGY
MMAR_5210|M.marinum_M GEPQ-------PELAALIAAGKIHSD----VLDAGCGYAELSLALAAEGY
MAV_0404|M.avium_104 GEPQ-------PELAALIEQGKFRSD----VLDAGCGCAELSLALAARGY
Mflv_1324|M.gilvum_PYR-GCK GEPQ-------PELAALWRDGRFRSE----VLDAGCGHAELSLALAADGY
Mvan_5471|M.vanbaalenii_PYR-1 GEPQ-------PELAALWRDGKFRSE----VLDAGCGHAELSLALAADGY
MUL_0662|M.ulcerans_Agy99 GEPQ-------PELATLIEQGKVHGE----VLDAGCGEAALAMALAGRGH
MAB_4799c|M.abscessus_ATCC_199 GEMQ-------PELAALHRQGRFESP----ILDAGCGIGSTSLALAGHGY
MLBr_01723|M.leprae_Br4923 SYDQRCVDYVRHCFDAIVPDELFTELPYDCALELGCGTGFFLLNLIQSGV
. * : :: . *: *** . : * *
MSMEG_6235|M.smegmatis_MC2_155 TVVG--MDLSPSAIAAANRAAQERNLAT-ASFVQGDITSFTGY----DGR
TH_1722|M.thermoresistible__bu TVVG--IDLSPTAIAAANRTAQERGLAT-ASFVQGDITDFGGY----DGR
Mb3725|M.bovis_AF2122/97 TVVG--IDLTPTAVAAATKAAEERGLTT-ASFVQADITEFAAYPAGSAGR
Rv3699|M.tuberculosis_H37Rv TVVG--IDLTPTAVAAATKAAEERGLTT-ASFVQADITEFAAYPAGSAGR
MMAR_5210|M.marinum_M TVVG--IDITPTAIAAATKAAAERGLGN-TSFMQADITDFNAYPAGSAGR
MAV_0404|M.avium_104 TVVG--IDLTPTAVAAATRAAAERGLTT-ASFVQADITSFTGY----DGR
Mflv_1324|M.gilvum_PYR-GCK TVTG--VDISPTAMAAASAAAAERGLSEKASFVAADITALSGF----DGR
Mvan_5471|M.vanbaalenii_PYR-1 TVTG--VDLSPTAVAAATAASAERGLSERTSFVAADITTLTGF----DGR
MUL_0662|M.ulcerans_Agy99 PVVG--LDISPTAVELAGREAARPGLTN-ASFAVADITDFASYPPESAGR
MAB_4799c|M.abscessus_ATCC_199 QVVG--LDLSSGAIEKAKKAAEPLALDV--VFDTADLTSDIGY----NDH
MLBr_01723|M.leprae_Br4923 ARRGSVTDLSPGMVKIATRNGQSLGLDINGRVADAEGIPYDDN------T
* *::. : * . * . .:
MSMEG_6235|M.smegmatis_MC2_155 FSTVIDSTLFHSLPVEGREGYLQSIHRASAPGA------------RYFVL
TH_1722|M.thermoresistible__bu FNTIIDSTLFHSIPVQARDGYLRSIHRAAAPGA------------RYFAL
Mb3725|M.bovis_AF2122/97 FSTVIDSTLFHSLPVDSRDRYLSSVHRAAAPGA------------SYYVL
Rv3699|M.tuberculosis_H37Rv FSTVIDSTLFHSLPVDSRDRYLSSVHRAAAPGA------------SYYVL
MMAR_5210|M.marinum_M FATVIDSTLFHSLPVSGRDDYLKSVHRAAAPGA------------SYFVL
MAV_0404|M.avium_104 FATVVDSTLFHSLPVEGRDGYLRSIHRAAAAGA------------SLFIL
Mflv_1324|M.gilvum_PYR-GCK FSTVVDSTLFHSLPVESRAGYLESVHRAARPGA------------GFFVL
Mvan_5471|M.vanbaalenii_PYR-1 FATVVDSTLFHSLPVESRDGYLQSVHRAAAPGA------------GYFVL
MUL_0662|M.ulcerans_Agy99 FNTIMDSTLFHSMPVELREGCQRSIVRAAAPGA------------SYFVL
MAB_4799c|M.abscessus_ATCC_199 FNTVIDGLVFHCLPAQIRGDYVRSLARSLKPGG------------RFFAL
MLBr_01723|M.leprae_Br4923 FDLVVGHAVLHHIPDVELS--LREVLRVLKPGGRFVFAGEPTDVGNRYAR
* ::. ::* :* .: * .*. :
MSMEG_6235|M.smegmatis_MC2_155 VFAKGAFPADLEVKP-----------NEVTEEELRTTVGKYWVVDDIRPA
TH_1722|M.thermoresistible__bu VFAKGAFPEEMEQGPGP---------NPVDEDELREAVSKYWEIDEIRPA
Mb3725|M.bovis_AF2122/97 VFAKGAFPAELEVKP-----------NEVDEDELRAAVSKYWKIDEIRPA
Rv3699|M.tuberculosis_H37Rv VFAKGAFPAELEVKP-----------NEVDEDELRAAVSKYWKIDEIRPA
MMAR_5210|M.marinum_M VFAKGAFPAALETKP-----------NEVDEDELRAAVGKYWEIDEIRPA
MAV_0404|M.avium_104 VFAKGAFPAEMQPKP-----------NEVDEDELRAAVGKYWVIDEIRPS
Mflv_1324|M.gilvum_PYR-GCK VFAKGAFPADTEQGP-----------NEVSEIELREAVSPYWTIDDIRPA
Mvan_5471|M.vanbaalenii_PYR-1 VFAKGAFPAEMEGGP-----------NEVTELELREAVSRYWIIDDIRPA
MUL_0662|M.ulcerans_Agy99 VFDKAALSGD---GP-I---------NGVTEEELRDAVSKHWVIDEIRPA
MAB_4799c|M.abscessus_ATCC_199 VFATEAFPPNAEFGP-----------RPFTEQQLRDIVGRHLVVDEVRRA
MLBr_01723|M.leprae_Br4923 VFADLTWKVTIRVVQLPGLSAWRRTQVEIDENSRAAALEWVVDLHTFEPK
** : . * . : :. ..
MSMEG_6235|M.smegmatis_MC2_155 FIHANA---------VVFPDAP----ELPPHGYDD--KGRIM------FP
TH_1722|M.thermoresistible__bu FIHAN-----------MPPDVP----GVESFDTDE--KGRTK------LP
Mb3725|M.bovis_AF2122/97 FIHVNPV--------TIPPQLAGAPVEFPPYDHDE--KGRVK------FP
Rv3699|M.tuberculosis_H37Rv FIHVNPV--------TIPPQLAGAPVEFPPYDHDE--KGRVK------FP
MMAR_5210|M.marinum_M FIHANVP--------VIPPLPAGSPIEFPPHQRDE--KGRMK------FP
MAV_0404|M.avium_104 FIVSN------------VPQIADAPFEFPAHERDE--RGRMK------MP
Mflv_1324|M.gilvum_PYR-GCK LIHTN------------VPKLPGMP-PPPLDMLDD--RGHLR------MQ
Mvan_5471|M.vanbaalenii_PYR-1 LIDTN------------VPKLPGMP-PPPLDMLDD--RGRLR------MQ
MUL_0662|M.ulcerans_Agy99 RIHANLP--------PEVPGCPPSTLATNPRAASPSVRGCSQPIWADGTP
MAB_4799c|M.abscessus_ATCC_199 RAWVN------------VPGQLPEGFEYRNVTIGS--DGRAQ------LP
MLBr_01723|M.leprae_Br4923 VLETMATNAGAVQVKTVTEEFTAAMLGWPLRTFESTMPPSKLG---WGWA
MSMEG_6235|M.smegmatis_MC2_155 AFLLEAHRD-----------------------------
TH_1722|M.thermoresistible__bu AFLLSAHKA-----------------------------
Mb3725|M.bovis_AF2122/97 AYLLTAHKAG----------------------------
Rv3699|M.tuberculosis_H37Rv AYLLTAHKAG----------------------------
MMAR_5210|M.marinum_M AYLLTAHKA-----------------------------
MAV_0404|M.avium_104 AYLLTAHKAQ----------------------------
Mflv_1324|M.gilvum_PYR-GCK AFLLSAHKEP----------------------------
Mvan_5471|M.vanbaalenii_PYR-1 AFLLQAHKES----------------------------
MUL_0662|M.ulcerans_Agy99 HAVYSPANEG----------------------------
MAB_4799c|M.abscessus_ATCC_199 AWLVSAHRS-----------------------------
MLBr_01723|M.leprae_Br4923 RFAFTSWKTLSWVDANVWRRVIPKSWFYNIIITGVKPS
. .