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DINGSVAIVTGAGSGIGQALAWGLVDAGATVVASDIDADAVGRTAAARDGIVGQRADASAVSDIEDLIAL AEKEFGPVDLYAANAGIAGGLGLGIGEAAWDLTIDVNLRAHIRAATLLVPGWVERGRGYFLSVASAAGLL TQIGSPAYSVTKHAAVGFAEWLSITYGGQGVGVSCLCPMGVKTALLDGLTESDDPDVRVAGTSITAAGDV LEPAVVAAMALDAIRDEKFLVLPHPQVLDMYRQKGADYDRWIAGMRRYQAILEDQIIR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3103c | - | - | 100% (269) | putative short chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_4043c | - | 4e-27 | 38.02% (192) | short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_4478c | - | 2e-26 | 36.84% (247) | putative short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1277c | - | 2e-21 | 31.52% (257) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_4800 | - | 4e-85 | 58.80% (267) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1245c | - | 3e-21 | 31.52% (257) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01094 | - | 3e-22 | 30.96% (239) | short chain alcohol dehydrogenase |
| M. marinum M | MMAR_4755 | - | 6e-25 | 32.69% (260) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_0895 | - | 4e-26 | 33.33% (264) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1760 | - | 6e-85 | 60.30% (267) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3454 | - | 4e-88 | 61.80% (267) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0326 | - | 2e-25 | 33.08% (260) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1642 | - | 2e-84 | 59.18% (267) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4800|M.gilvum_PYR-GCK --------------------------MELAGRTAIVTGAASGIGAALATE
Mvan_1642|M.vanbaalenii_PYR-1 MRERACLRPTRRLWDELCARSRHTLGMELARKTAIVTGGASGIGAAIASE
MSMEG_1760|M.smegmatis_MC2_155 --------------------------MDIDGTTAVVTGGGSGIGAALAEA
TH_3454|M.thermoresistible__bu --------------------------MRIDNSVFVVTGAGSGIGRALALS
MAB_3103c|M.abscessus_ATCC_199 --------------------------MDINGSVAIVTGAGSGIGQALAWG
MMAR_4755|M.marinum_M ---------------------MD----GFAGRGAVITGGASGIGLATATE
MUL_0326|M.ulcerans_Agy99 ---------------------MD----GFAGSGAVITGGASGIGLATATE
MAV_0895|M.avium_104 ---------------------MDGFLSGFDGRAAVVTGGASGIGLATATE
Mb1277c|M.bovis_AF2122/97 -------------------------MEGFAGKVAVVTGAGSGIGQALAIE
Rv1245c|M.tuberculosis_H37Rv -------------------------MEGFAGKVAVVTGAGSGIGQALAIE
MLBr_01094|M.leprae_Br4923 -------------------------MEGFAGKVAVVTGAGSGIGQALAIE
: ::**..**** * *
Mflv_4800|M.gilvum_PYR-GCK LARRGVSVVIGDLDDDGAHATASAIRADGGAAAALRADATSVADIEALIT
Mvan_1642|M.vanbaalenii_PYR-1 LAAHGVSVVVGDLDEAGAHTTAAAIRDSGGAATALRADASDVVDIEGLIT
MSMEG_1760|M.smegmatis_MC2_155 FAAAGARVVVADLDEPGAAATAARIESAGGNAVAVRADASATADIEALT-
TH_3454|M.thermoresistible__bu FADAGARVVAGDIDESAADTTAATIRDSGGHAVPIRADATTPAGIDAMIS
MAB_3103c|M.abscessus_ATCC_199 LVDAGATVVASDIDADAVGRTAAARDG----IVGQRADASAVSDIEDLIA
MMAR_4755|M.marinum_M FARRGAKVVLADIDKPGLERSVEHLRGKGFDAHGVMCDVRHLSEVNHLAA
MUL_0326|M.ulcerans_Agy99 FARRGAKVVLADIDKPGLERSVEHLRGKGFDAHGVMCDVRHLSEVNHLAA
MAV_0895|M.avium_104 FARRGARLVLSDVDQPALEQAVNGLRGQGFDAHGVVCDVRHLDEMVRLAD
Mb1277c|M.bovis_AF2122/97 LARSGAKVAISDVDTDGLADTEHRLKAISTPVKTDRLDVTEREAFLAYAD
Rv1245c|M.tuberculosis_H37Rv LARSGAKVAISDVDTDGLADTEHRLKAISTPVKTDRLDVTEREAFLAYAD
MLBr_01094|M.leprae_Br4923 LARSGAKLAISDVDGEGLAQTEGQLKAIGASARTDRLDVTEREAFLTYAD
:. *. :. .*:* . : *. .
Mflv_4800|M.gilvum_PYR-GCK LASREFTPVDIYVANAGVIGKPGLGT--ESDWDVILDVNLRAHVRAARLL
Mvan_1642|M.vanbaalenii_PYR-1 LAGREFAPVDIYVANAGITGKPGLGT--ESDWDVVLDVNLRAHVRAARLV
MSMEG_1760|M.smegmatis_MC2_155 --RTEFGPVDIYVANAGIIGASGLGT--DEEWDRILAVNLRAHIRAADVL
TH_3454|M.thermoresistible__bu LAQETFGPVDGYVANAGVIGPPGLGT--DTGWDRVLDVNLRAHVRAADAL
MAB_3103c|M.abscessus_ATCC_199 LAEKEFGPVDLYAANAGIAGGLGLGIG-EAAWDLTIDVNLRAHIRAATLL
MMAR_4755|M.marinum_M ESARLLGQIDVVFSNAGIVVAGPIADMTHDDWRWVIDIDLWGSIHTVEAF
MUL_0326|M.ulcerans_Agy99 ESARLLGQIDVVFSNAGIVVAGPIADMTHDVWRWVIDIDLWGSIHTVEAF
MAV_0895|M.avium_104 EAFRLLGGVDVVFSNAGIVVAGPLAQMNHDDWRWVIDIDLWGSIHAVEAF
Mb1277c|M.bovis_AF2122/97 AVNEHFGTVNQIYNNAGIAFTGDIEVSQFKDIERVMDVDFWGVVNGTKAF
Rv1245c|M.tuberculosis_H37Rv AVNEHFGTVNQIYNNAGIAFTGDIEVSQFKDIERVMDVDFWGVVNGTKAF
MLBr_01094|M.leprae_Br4923 VVHENFGKVNQIYNNAGIAFTGDVEVSHFKDIERVMDVDYWGVVNGTKAF
: :: ***: : : :: . :. . .
Mflv_4800|M.gilvum_PYR-GCK VPHWQSVGS-GYFVSVASAAGLLTQLGAAGYAVSKHAAVGFAEWLAVTYG
Mvan_1642|M.vanbaalenii_PYR-1 VPHWQSRGS-GYFVSVASAAGLLTQLGAAGYAVTKHAAVGFAEWLAITYG
MSMEG_1760|M.smegmatis_MC2_155 VPQWISRGR-GYFVSVASAAGLLSQIGAAGYAVTKHAAVGFAEWLAITYG
TH_3454|M.thermoresistible__bu VPQWISRGT-GYFVSVASAAGLLTQLGAAAYAVSKHAAVGFAEWLAITYG
MAB_3103c|M.abscessus_ATCC_199 VPGWVERGR-GYFLSVASAAGLLTQIGSPAYSVTKHAAVGFAEWLSITYG
MMAR_4755|M.marinum_M LPKLLEHG--GHIAFTASFAGLVPNAGLGAYGVAKYGVVGLAETLSREMK
MUL_0326|M.ulcerans_Agy99 LPKLLEHG--GHIAFTASFAGLVPNAGLGAYGVAKYGVVGLAETLSREMK
MAV_0895|M.avium_104 LPRLLEQGTGGHIAFTASFAGLVPNAGLGTYGVAKYGVVGLAETLAREVK
Mb1277c|M.bovis_AF2122/97 LPHLIASGD-GHVINISSVFGLFSAPGQAAYNSAKFAVRGFTEALRQEMA
Rv1245c|M.tuberculosis_H37Rv LPHLIASGD-GHVINISSVFGLFSAPGQAAYNSAKFAVRGFTEALRQEMA
MLBr_01094|M.leprae_Br4923 LPYLISSGD-GHVINISSVFGLFSVPGQAAYNSAKFAVRGFTEALREEMA
:* * *:. :* **.. * * :*... *::* *
Mflv_4800|M.gilvum_PYR-GCK DDG--IGVSCVCPLGVKTPLLQGIRGIDDPDARLGASS--------IEQS
Mvan_1642|M.vanbaalenii_PYR-1 DDG--IGVSCVCPLGVDTPLLQAIRSTDDPDSRLGASS--------IEQS
MSMEG_1760|M.smegmatis_MC2_155 DDG--VGVSCVCPLGVDTPLLHAVRNSAETDALVGAES--------IVQS
TH_3454|M.thermoresistible__bu DRG--IGVSCVCPMGVRTPLLGAVRDSTDTTAQLAARS--------ITSA
MAB_3103c|M.abscessus_ATCC_199 GQG--VGVSCLCPMGVKTALLDGLTESDDPDVRVAGTS--------ITAA
MMAR_4755|M.marinum_M DRG--VGVTVLCPMVVETRLVSNSERIRGADYGLSSAPQVTGDMGSLPAQ
MUL_0326|M.ulcerans_Agy99 DRG--VGVTVLCPMVVETQLVSNSERIRGADYGLSSAPQVTGDMGSLPAQ
MAV_0895|M.avium_104 PNG--IGVSVLCPMVVETKLVSNSERIRGADYGMSATP--EGAFGPLPTQ
Mb1277c|M.bovis_AF2122/97 LAGHPVKVTTVHPGGVKTAIARNATAAEGLDQAELAET--------FDKR
Rv1245c|M.tuberculosis_H37Rv LAGHPVKVTTVHPGGVKTAIARNATAAEGLDQAELAET--------FDKR
MLBr_01094|M.leprae_Br4923 LAGRPVNVTTVYPGGIKTAIARNATAAEGLDVSKIASR--------FDTW
* : *: : * : * : . :
Mflv_4800|M.gilvum_PYR-GCK AGVISAADVATVTVEAIREE--RFLVLPHAELLEMYRRKGG--DYDRWIS
Mvan_1642|M.vanbaalenii_PYR-1 GSVISAADVAAVTVEAIRTD--RFLVLPHPELLEMYRNKGG--DYDRWIG
MSMEG_1760|M.smegmatis_MC2_155 GDVITPQDVATVTVEAVQAG--RFLVLPHPHVLDLYRRKGS--DYDRWIA
TH_3454|M.thermoresistible__bu GAVLDAAEVADLTVAAVREG--RFLVLPHPEVLDMYRQKGA--DYDRWIA
MAB_3103c|M.abscessus_ATCC_199 GDVLEPAVVAAMALDAIRDE--KFLVLPHPQVLDMYRQKGA--DYDRWIA
MMAR_4755|M.marinum_M DDSLSVDELARLTADAILAN--RLYVLPHEGARTSIQRRFA--RIDRTFD
MUL_0326|M.ulcerans_Agy99 DDSLSVDELARLTADAILAN--GLYVLPHEGARTSIQRRFA--RIDRTFD
MAV_0895|M.avium_104 DESVSADDVARLTADAILAN--RLYILPHAAARESIRRRFE--RIDRTFD
Mb1277c|M.bovis_AF2122/97 VAHLSPQRAAQIILTGVAKNKARVLVGVDAKVLDLVVRLTG-SGYQRIFP
Rv1245c|M.tuberculosis_H37Rv VAHLSPQRAAQIILTGVAKNKARVLVGVDAKVLDLVVRLTG-SGYQRIFP
MLBr_01094|M.leprae_Br4923 VAHTSPQHAARIILKAVRKKKARVLVGPDAKVANVVVRFSGGAGYQRLFA
* : .: . : . . :* :
Mflv_4800|M.gilvum_PYR-GCK GMRRYQRTLRSL-----
Mvan_1642|M.vanbaalenii_PYR-1 GMRRYQRTLRAL-----
MSMEG_1760|M.smegmatis_MC2_155 GMRRYQRSLRGTAVPGT
TH_3454|M.thermoresistible__bu GMRRYQRSLAAER----
MAB_3103c|M.abscessus_ATCC_199 GMRRYQAILEDQIIR--
MMAR_4755|M.marinum_M EQAAEGWRH--------
MUL_0326|M.ulcerans_Agy99 EQAAEGWRH--------
MAV_0895|M.avium_104 EQAAEGWTH--------
Mb1277c|M.bovis_AF2122/97 IITGRLIPRPR------
Rv1245c|M.tuberculosis_H37Rv IITGRLIPRPR------
MLBr_01094|M.leprae_Br4923 QVASRLILNQR------