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KFTEIPMDGAVALVTGGARGIGLAIAHRLADMGARVMIADLDGAAAKEAAREVGSGARGFFLDVTEFDEY LRVVTEIEDSIGPVDIVVNNAGIMPVGPLLGESRGVAEATMRVNFWSHYNSYQVLAPRMVDRGRGHFINV TSAAGAIHSPGLASYVASKHAATGFARSAREELVGTGVTISTVMPSAVRTQLVDGIPFKWWEKLGIIPPG WVARDAVRTVRNRPAVVGSPRGTVLALRLQHLVPEWLWLLGRRVVNADRTVGPVDRQARSEYDGRIERQV EAAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4043c | - | - | 100% (285) | short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_1526 | - | 3e-48 | 39.64% (280) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4335 | - | 1e-37 | 35.40% (274) | putative short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1896c | - | 8e-39 | 45.95% (185) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0217 | - | 1e-30 | 31.02% (274) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv1865c | - | 8e-39 | 45.95% (185) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01094 | - | 5e-28 | 35.98% (189) | short chain alcohol dehydrogenase |
| M. marinum M | MMAR_2743 | - | 8e-41 | 38.58% (267) | short-chain type dehydrogenase |
| M. avium 104 | MAV_2700 | - | 4e-37 | 34.28% (283) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0771 | - | 2e-31 | 31.88% (276) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3427 | - | 1e-31 | 33.09% (275) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3011 | - | 6e-40 | 38.20% (267) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_2345 | - | 2e-35 | 36.90% (271) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2700|M.avium_104 --------------------------MDLTDKVVAITGGARGIGLATAKA
Mvan_2345|M.vanbaalenii_PYR-1 MVPSRPARGPRTSAQLGMKGGTVTADRNLTGRVVAITGAARGIGAATARA
Mb1896c|M.bovis_AF2122/97 -MPGRTSIG-------------VKIRDKVQDKVIAITGGARGIGLATAAA
Rv1865c|M.tuberculosis_H37Rv -MPGRTSIG-------------VKIRDKVQDKVIAITGGARGIGLATAAA
MMAR_2743|M.marinum_M -MADSTTIG-------------VRVR----DKVIVITGGARGIGLATATA
MUL_3011|M.ulcerans_Agy99 -MADSTTIG-------------VRVR----NKVIVITGGARGIGLATATA
Mflv_0217|M.gilvum_PYR-GCK -------------------------MDNIRGKTIAITGAARGIGYATAEA
MSMEG_0771|M.smegmatis_MC2_155 -------------------------MDNIRGKTIAITGAARGIGYATAKA
TH_3427|M.thermoresistible__bu -------------------------MDNIRGKTIAITGAARGIGYATATA
MAB_4043c|M.abscessus_ATCC_199 ---------------------MKFTEIPMDGAVALVTGGARGIGLAIAHR
MLBr_01094|M.leprae_Br4923 -------------------------MEGFAGKVAVVTGAGSGIGQALAIE
. . :**.. *** * *
MAV_2700|M.avium_104 VLAEGAKVALGDLDTELAEKQAVELGGD-PAVVGLPLDVSDPASFAAFLD
Mvan_2345|M.vanbaalenii_PYR-1 FAAAGASVAIGDLDADLAVRTAAEIG-----CLGSGVDVTDHDSVEKFLD
Mb1896c|M.bovis_AF2122/97 LHNLGAKVAIGDIDEAMAKESGADLD----LDMYGKLDVTDPDSFSGFLD
Rv1865c|M.tuberculosis_H37Rv LHNLGAKVAIGDIDEAMAKESGADLD----LDMYGKLDVTDPDSFSGFLD
MMAR_2743|M.marinum_M LHKLGAKVAIGDVDEPAVKEAGADLG----LEVYGKLDVTDPNSFSDFLD
MUL_3011|M.ulcerans_Agy99 LHKLGAKVAIGDVGEPAVKEAGADLG----LEVYGKLDVTDPNSFSDFLD
Mflv_0217|M.gilvum_PYR-GCK LLAHGARVVIGDRDVALQESSVAKLTNL-GPVSGYPLDVTDQESFATFLD
MSMEG_0771|M.smegmatis_MC2_155 LLAHGARVVIGDRDVALQESAVVELSKL-GQVSGYPLDVTDRESFATFLD
TH_3427|M.thermoresistible__bu LLARGARVVIGDRDVALQESAVAQLGRL-GPVSGYPLDVTDRESFATFLD
MAB_4043c|M.abscessus_ATCC_199 LADMGARVMIADLDGAAAKEAAREVG---SGARGFFLDVTEFDEYLRVVT
MLBr_01094|M.leprae_Br4923 LARSGAKLAISDVDGEGLAQTEGQLKAIGASARTDRLDVTEREAFLTYAD
. ** : :.* . .: :**::
MAV_2700|M.avium_104 DVEARLG-RLDVLVNNAGIMPTGPFVDESPTMSRRMIDVNVYGVLNGSRL
Mvan_2345|M.vanbaalenii_PYR-1 EVEQRLG-PLDVMVNNAGIMPVTQMLDESPESVRRQLAVNVAGVVFGTQH
Mb1896c|M.bovis_AF2122/97 AVERQLG-PIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKL
Rv1865c|M.tuberculosis_H37Rv AVERQLG-PIDVLVNNAGIMPVGRIVDEPDPVTRRILDINVYGVILGSKL
MMAR_2743|M.marinum_M QVERQLG-PLDVLVNNAGIMPVGRIVDEPDSVTRRILDINVYGVMVGSKL
MUL_3011|M.ulcerans_Agy99 QVERQLG-PLDVLVNNAGIMPVGRIVDEPDSVTRRILDINVYGVMVGSKL
Mflv_0217|M.gilvum_PYR-GCK KARTDGGGHIDVLINNAGVMPVGPFLDETEQSIRSSLEVNVYGVLTGCRL
MSMEG_0771|M.smegmatis_MC2_155 KARTDGGGHIDVLINNAGVMPVGPFLEQSEQSIRSNIEVNVYGVLTGCQL
TH_3427|M.thermoresistible__bu KARTDGGGHIDVLINNAGVMPIGPFLEQSEQAIRSSIEVNLYGVLTGCQL
MAB_4043c|M.abscessus_ATCC_199 EIEDSIG-PVDIVVNNAGIMPVGPLLGESRGVAEATMRVNFWSHYNSYQV
MLBr_01094|M.leprae_Br4923 VVHENFG-KVNQIYNNAGIAFTGDVEVSHFKDIERVMDVDYWGVVNGTKA
. * :: : ****: . . . : :: . . :
MAV_2700|M.avium_104 AAARFVPRGAGHIVNIASLAGVTGEPGMATYCGTKHFVVGFTESLHRELR
Mvan_2345|M.vanbaalenii_PYR-1 AASRMVARRSGHIVNVASAAGRIAFGGVATYTATKFAVVGFTEAAALELR
Mb1896c|M.bovis_AF2122/97 AAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYR
Rv1865c|M.tuberculosis_H37Rv AAQRMVPRGRGHVINVASLAGEIYAVGVATYCASKHAVVAFTDSARLEYR
MMAR_2743|M.marinum_M AAQRMVPRGRGHVINVASLAGEIYVVGLATYCASKHAVIAFTDAARIEYR
MUL_3011|M.ulcerans_Agy99 AAQRMVPRGRGHVINVASLAGEIYVVGLATYCASKHAVIAFTDAARIEYR
Mflv_0217|M.gilvum_PYR-GCK ALPDMVKRRSGHIINIASLSGVIPLPGQVVYVGAKYAVVGLTTALADEMA
MSMEG_0771|M.smegmatis_MC2_155 ALPDMVKRRRGHIINIASLSGVIPLPGQVVYVGAKYAVVGLSTALADEMA
TH_3427|M.thermoresistible__bu ALPDMVRRRSGHIINIASMSGLIPVPGQVPYNAAKFGVVGLSVALADEMA
MAB_4043c|M.abscessus_ATCC_199 LAPRMVDRGRGHFINVTSAAGAIHSPGLASYVASKHAATGFARSAREELV
MLBr_01094|M.leprae_Br4923 FLPYLISSGDGHVINISSVFGLFSVPGQAAYNSAKFAVRGFTEALREEMA
:: **.:*::* * * . * .:*. . .:: : *
MAV_2700|M.avium_104 PHR--VGVSLVLPGIINTELSAGTKVPGWARPLATAEPEDVAAGIVAAVS
Mvan_2345|M.vanbaalenii_PYR-1 DSG--VRFTCVLPGVVNTELTSGLRDHWLLR---SCEPEEVAAGVVAGVR
Mb1896c|M.bovis_AF2122/97 SAG--VKFSMVLPSFVNTELIAGTGG---IKGFKNAEPADIADAIVGLIV
Rv1865c|M.tuberculosis_H37Rv SAG--VKFSMVLPSFVNTELIAGTGG---IKGFKNAEPADIADAIVGLIV
MMAR_2743|M.marinum_M STG--VKFSMVLPTFVNTELASGTPG---MKGFKNAEPSDIADAIVALVA
MUL_3011|M.ulcerans_Agy99 TTG--VKFSMVLPTFVNTELASGTPG---MKGFKNAEPSDIADAIVALVA
Mflv_0217|M.gilvum_PYR-GCK PHG--VNVSVIMPPFTNTELIAGTKS---GGAIKPVEPEDIAAAIVKTLN
MSMEG_0771|M.smegmatis_MC2_155 PYG--VDVSVIMPPFTNTDLISGTKS---GGAIKPVEPEEIAAAIVKTLN
TH_3427|M.thermoresistible__bu PYG--VEVSVVMPPFTRTELISGTKE---TAATKPAEPEDIAAAIVKTLD
MAB_4043c|M.abscessus_ATCC_199 GTG--VTISTVMPSAVRTQLVDGIPFK-WWEKLGIIPPGWVARDAVRTVR
MLBr_01094|M.leprae_Br4923 LAGRPVNVTTVYPGGIKTAIARNATA---AEGLDVSKIASRFDTWVAHTS
* .: : * .* : . *
MAV_2700|M.avium_104 KDKPRKTVPATLGALLKSVSLLPDTPRFAVAHAVRFDRLVSG-ADPDARA
Mvan_2345|M.vanbaalenii_PYR-1 RHRRTVYVPARLRPVSWAYGLLPGAARTQVMAALGAGHRMLD-GDDTARR
Mb1896c|M.bovis_AF2122/97 HPKPRVRVTKAAGSMIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRR
Rv1865c|M.tuberculosis_H37Rv HPKPRVRVTKAAGSMIVAQRFMPRQVSEGLNRLLGGEHVFTDDVDMEKRR
MMAR_2743|M.marinum_M NPKPRVRVTKAAGAMIASQKYLPRWLSEGLNRLLGGEHVFTDDVDAAKRE
MUL_3011|M.ulcerans_Agy99 NPKPRVRVTKAAGAMIASQKYLPRWLSEGLNRLLGGEHVFTDDVDAAKRE
Mflv_0217|M.gilvum_PYR-GCK KPKTHVSVPPPLRFTAQAAQMLPPKGRRAMNKALGLDTVFLD-VDTDKRK
MSMEG_0771|M.smegmatis_MC2_155 KPKTHVSVPPPLRFTAQAAQMLPPKGRRWLNKKLGLDNVFLE-FDTAKRK
TH_3427|M.thermoresistible__bu KPKTHVSVPGPLRFIAQAAQTLGPRGRRWLNKRLGLDTVFLE-FDQQARQ
MAB_4043c|M.abscessus_ATCC_199 NRPAVVGSPRGTVLALRLQHLVPEWLWLLGRRVVNADRTVGP-VDRQARS
MLBr_01094|M.leprae_Br4923 PQHAARIILKAVRKKKARVLVGPDAKVANVVVRFSGGAGYQRLFAQVASR
.
MAV_2700|M.avium_104 AYHRRLAEES-----------------
Mvan_2345|M.vanbaalenii_PYR-1 DYNRRIDTR------------------
Mb1896c|M.bovis_AF2122/97 TYEARARGEE-----------------
Rv1865c|M.tuberculosis_H37Rv TYEARARGEE-----------------
MMAR_2743|M.marinum_M AYEARARGETGES--------------
MUL_3011|M.ulcerans_Agy99 AYEARARGETGES--------------
Mflv_0217|M.gilvum_PYR-GCK GYEERARAARGVVEGSQG---------
MSMEG_0771|M.smegmatis_MC2_155 AYEDRAQAALGVVESEKK---------
TH_3427|M.thermoresistible__bu GYEQRAQQALGVLEGGNKQQDRSGQKS
MAB_4043c|M.abscessus_ATCC_199 EYDGRIERQVEAAR-------------
MLBr_01094|M.leprae_Br4923 LILNQR---------------------
: