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M. abscessus ATCC 19977 MAB_0377 (-)

annotation: TetR family transcriptional regulator
coordinates: 373238 - 373849
length: 203

MPTPRRTQEERSAAMRARLLEATIDCLVEFGYSGTTTSRIASRAGATRGALIHHFQSKSELMAESVRHLA
FKRTQAVLEELMAMDQSADPIERYLDVLWRIHQGPLFIAVVELLIAARTEPDLRVHLDQFEKIVLHNLSA
LNVLGDDDVGSPKERRDLGLLAMDIIRGLLVSSLTASQETRDRRWSRAKHMLELRLRAPSPEA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_0377--100% (203)TetR family transcriptional regulator
M. abscessus ATCC 19977MAB_2392-4e-6058.08% (198) putative transcriptional regulator, TetR
M. abscessus ATCC 19977MAB_2952c-1e-4145.95% (185) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2936c-4e-1330.25% (119) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0925-1e-0923.94% (188) TetR family transcriptional regulator
M. tuberculosis H37RvRv2912c-4e-1330.25% (119) TetR family transcriptional regulator
M. leprae Br4923MLBr_02677-1e-0633.70% (92) putative TetR-family transcriptional regulator
M. marinum MMMAR_1796-2e-1332.77% (119) TetR family transcriptional regulator
M. avium 104MAV_3767-7e-1431.09% (119) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_6139-3e-1330.65% (124) putative HTH-type transcriptional regulator
M. thermoresistible (build 8)TH_0251-7e-0927.10% (107) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. ulcerans Agy99MUL_2044-9e-1331.93% (119) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_2337-1e-3845.45% (187) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MAB_0377|M.abscessus_ATCC_1997      -------MPTPRRTQEERSAAMRARLLEATIDCLVEFGYSGTTTSRIASR
Mvan_2337|M.vanbaalenii_PYR-1       MRTGVERAATRRRTQAERTAAMRTRLLDATVECLVTYGYAGTTTPRIVEI
Mb2936c|M.bovis_AF2122/97           ----------MARTQQQRREETVARLLQASIDTIIEVGYARASAAVITKR
Rv2912c|M.tuberculosis_H37Rv        ----------MARTQQQRREETVARLLQASIDTIIEVGYARASAAVITKR
MMAR_1796|M.marinum_M               ----------MARTQQQRREETVARLLQASIDTIVEVGYARASAAIITKR
MUL_2044|M.ulcerans_Agy99           ----------MARTQQQRREETVARLLQASIDTIVGVGYARASAAIITKR
MAV_3767|M.avium_104                ----------MARTQQQRREETVARLLDASIATIIEVGYARASAAVITKR
MSMEG_6139|M.smegmatis_MC2_155      ----------MARTQQQRREETVARLLDASIQTIIDVGYARASAAVIARR
Mflv_0925|M.gilvum_PYR-GCK          -MARSPAARRPPGGNQERAERTRRTVIDETVRYILDEGFAAPSVRRITER
MLBr_02677|M.leprae_Br4923          -------MESQRRTQEERSTATRDALTLARHRLWRLRGYAEVGTPEIAKE
TH_0251|M.thermoresistible__bu      -------------VTDDHLAARRRQILDGARRCFAEYGYEQATVRRLEQA
                                                    ::       :           *:    .  :   

MAB_0377|M.abscessus_ATCC_1997      AGATRGALIHHFQSKSELMAESVRHLAFKRTQAVLEELMAMD--QSADPI
Mvan_2337|M.vanbaalenii_PYR-1       AGVTRGAQVHHFRSKEDLVVAAIEHLAEQRIQAAIRQNGRLL--SSPDPV
Mb2936c|M.bovis_AF2122/97           AGVSVGALFRHFETMGDFMAATAYEVLRRQLETFTKQVAEIP--ADRPAL
Rv2912c|M.tuberculosis_H37Rv        AGVSVGALFRHFETMGDFMAATAYEVLRRQLETFTKQVAEIP--ADRPAL
MMAR_1796|M.marinum_M               AGVSVGALFRHFETMGDFMAATAYEVLRRQLDIFTKQVAEIP--ADRPAL
MUL_2044|M.ulcerans_Agy99           AGVSVGALFRHFETMGDFMAATAYEVLRRQLDIFTKQVAEIP--ADRPAL
MAV_3767|M.avium_104                AGVSVGALFRHFDTMGDFMAATASEVLRRQLESFTKRVAEIP--ADQPVL
MSMEG_6139|M.smegmatis_MC2_155      AQVSDGALFRHFPTMGDFMAATAHEVMRRQLEVFTKRIAEIP--AEEPPL
Mflv_0925|M.gilvum_PYR-GCK          AGLTWGVVQYHFGDLGGLLMAVVDQGIAELTGALERLRTETANLPAEHRT
MLBr_02677|M.leprae_Br4923          ADTTRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKTPVDAI
TH_0251|M.thermoresistible__bu      TGLSRGAIFHHFKDKDTLFFELAREDAERMAEVASR----------EGLI
                                    :  : *.   :*     :.                               

MAB_0377|M.abscessus_ATCC_1997      ERYLDVLWRIHQGPLFIAVVELLIAART----------------------
Mvan_2337|M.vanbaalenii_PYR-1       PRVLDFLWESHQGDMFVATIELWVAART----------------------
Mb2936c|M.bovis_AF2122/97           PAALTILRDITAGSTNAVLYELMVAART----------------------
Rv2912c|M.tuberculosis_H37Rv        PAALTILRDITAGSTNAVLYELMVAART----------------------
MMAR_1796|M.marinum_M               EAALAILRDITAGATNAVLYELMIAART----------------------
MUL_2044|M.ulcerans_Agy99           EAALAILRDITAGATNAVLYELMIAART----------------------
MAV_3767|M.avium_104                EAVLGILRDLTSGPVNAVIYELTVAART----------------------
MSMEG_6139|M.smegmatis_MC2_155      QAVLTILRDVTGNDTNTVMYELLIAART----------------------
Mflv_0925|M.gilvum_PYR-GCK          EVVVDALWQAFSSPTSMAALEILISTRA----------------------
MLBr_02677|M.leprae_Br4923          RAKVDAWLEGLADPQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQQLL
TH_0251|M.thermoresistible__bu      QVMRDLIAAPEQYDWLTTRLEIARKLRN----------------------
                                                         :                            

MAB_0377|M.abscessus_ATCC_1997      --EPDLRVHLDQFEKIVLHNLSALNVLGDDDVGSPKER-----RDLGLLA
Mvan_2337|M.vanbaalenii_PYR-1       --DDVLAREVARVEPMVNSTLVAAIDQLLPNTFSHKRI-----RNAIFTA
Mb2936c|M.bovis_AF2122/97           --DEKLKETLQNVLGQYSAKIHDAARALPGAESFPEET----FPVIVALM
Rv2912c|M.tuberculosis_H37Rv        --DEKLKETLQNVLGQYSAKIHDAARALPGAESFPEET----FPVIVALM
MMAR_1796|M.marinum_M               --DDKLKETLQHVLGQYRAKIYDAARTLPGAEGFPEET----FPAIVAVL
MUL_2044|M.ulcerans_Agy99           --DDKLKETLQHVLGQYRAKIYDAARTLPGAEGFPEGT----FPAIVAVL
MAV_3767|M.avium_104                --DEKLRETLQHELAQYAAKIDEVSRALPGVEGFPADT----FPVLVALM
MSMEG_6139|M.smegmatis_MC2_155      --DEKLRVTLQEVLTEYAANIYETARTIPGFEQFPQNESRHEAMAAVALL
Mflv_0925|M.gilvum_PYR-GCK          --ARDSDVNAQLVDTMR--QFTELGRHLGEDLDAPQAT------EIGNLI
MLBr_02677|M.leprae_Br4923          SEASRARQLAQPLDHVLIGKLYESAMAIRRHHRLPEASPARNQTGAAPTH
TH_0251|M.thermoresistible__bu      --DPEFHRGWSELSAELAAATTARLRRQKQAGRLRDDVPG---EVLRTYL
                                                                                      

MAB_0377|M.abscessus_ATCC_1997      MDIIRG---LLVSSLTAS-QETRDRRWSRAKHMLELRLRAPSPEA---
Mvan_2337|M.vanbaalenii_PYR-1       MDALRG---ILVVSFVDRDLDLARRRWDRACVDLGSALADALKAAPSE
Mb2936c|M.bovis_AF2122/97           TNVFDG---AAIVRGVLPQPELEEQRIPMLTALLTAGL----------
Rv2912c|M.tuberculosis_H37Rv        TNVFDG---AAIVRGVLPQPELEEQRIPMLTALLTAGL----------
MMAR_1796|M.marinum_M               TNVFDG---AAIVGAVLPQPDIDEQRIPVLAALLSAAVPDTAP-----
MUL_2044|M.ulcerans_Agy99           TNVFDG---AAIVGAVLPQPDIDEQRIPVLAALLSAAVPDTAP-----
MAV_3767|M.avium_104                RNVFDG---AAVVEGVLPQPEIAAQRIPVLTALLNAALPQ--------
MSMEG_6139|M.smegmatis_MC2_155      VNTFDG---AAIIRPVLPQPDLEDARIALLSSLFSR------------
Mflv_0925|M.gilvum_PYR-GCK          WATLRG---IVLAQMVSPQPLDTSRDRRTLVDVLNTYMRAKGR-----
MLBr_02677|M.leprae_Br4923          REHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSSLL-----
TH_0251|M.thermoresistible__bu      ELVLDG-----LVARLASGDDPE--KLSAVLDLVEASVRHQGSE----
                                       .       :                     .