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SVAPLSQRIKALENELGEQLFDRSTHHVELTNAGERLVPLARTIVSDFDALPRKLLLGMPAGAVRVGVTR ALNGRSRRTISDVLAELSRDHTYIVNQVASRDMERQLLAGSIDLGVSRVPAASARVQARLLNTERLAILA DASAFPAKVSVQLADLRGYTYVHGPEAWEIASMLEAQHVLFDSGVLNDSLTRCDDVSSMLLTLRNSTKIT LRSLQSEELKGLDPAEFVLLPIDDLTVEIPTMLQWRAEDVDRLPIAEAIKSITAAVAGDRLGD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2764c | - | - | 100% (274) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2238 | - | 3e-08 | 25.14% (183) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3208c | - | 4e-08 | 24.16% (178) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2332 | - | 1e-11 | 29.18% (281) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_02041 | oxyR | 3e-05 | 45.65% (46) | putative LysR-family transcriptional regulator |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2838 | - | 2e-06 | 31.58% (133) | hydrogen peroxide-inducible genes activator |
| M. smegmatis MC2 155 | MSMEG_1902 | - | 3e-13 | 27.69% (242) | transcriptional regulator |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 8e-05 | 30.71% (127) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_4315 | - | 4e-11 | 28.11% (281) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02041|M.leprae_Br4923 ---MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALE
MAV_2838|M.avium_104 ---MPDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQALAALE
MUL_2998|M.ulcerans_Agy99 MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQALAALE
Mflv_2332|M.gilvum_PYR-GCK --------MDIDFTRLRYFVAVADELHFKRAADKLRITPPPLSKQIKLLE
Mvan_4315|M.vanbaalenii_PYR-1 --------MDIDFTRLRYFVAVADELHFKRAADKLMITPPPLSKQIKLLE
MSMEG_1902|M.smegmatis_MC2_155 --------MEIDFTRLRYFVAVAEELHFKRAADRLMITPPPLSKQIKLLE
MAB_2764c|M.abscessus_ATCC_199 ------------------------------------MSVAPLSQRIKALE
: ..**: : **
MLBr_02041|M.leprae_Br4923 SGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLR
MAV_2838|M.avium_104 AGLGTQLVERSTRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGSADPLR
MUL_2998|M.ulcerans_Agy99 AGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGEADPLN
Mflv_2332|M.gilvum_PYR-GCK KELGGPLFERGYHEVRLSPLGERLVGPAREILRQVEDFKAAATQGVRGLA
Mvan_4315|M.vanbaalenii_PYR-1 KELGGPLFERGYHDVRLTPLGQRLVGPAREILRQVEEFKAVATQAVRGLA
MSMEG_1902|M.smegmatis_MC2_155 KELGGQLFERNYHEVRLTPLGEKLLGPARDILARVEDLKATASRITQGVA
MAB_2764c|M.abscessus_ATCC_199 NELGEQLFDRSTHHVELTNAGERLVPLARTIVSDFDALPRKLLLGMP--A
*. *.:*. : * :: * *: *: : : :
MLBr_02041|M.leprae_Br4923 GGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLTALREGA
MAV_2838|M.avium_104 AGMRLGLIPTVAPYVLPTVLAGIAERRPGLTLRVTEDQTERLLAVLREGA
MUL_2998|M.ulcerans_Agy99 GSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVIEDQTERLLTALREGS
Mflv_2332|M.gilvum_PYR-GCK P-LRVSATAYAPSDLLGELEAVLAG-LPGPTEFSVPGSAAEVTAKLIAGQ
Mvan_4315|M.vanbaalenii_PYR-1 P-VRVSATAYAPSDLLGELEAAIAS-LPVPTEFSVPGSAAEVTAKLIAGQ
MSMEG_1902|M.smegmatis_MC2_155 P-VRVGATAYAPSDFLARLEKAVAG-LAAPTQFSVPGSAAEVTAKLVSGH
MAB_2764c|M.abscessus_ATCC_199 GAVRVGVTRALNGRSRRTISDVLAELSRDHTYIVNQVASRDMERQLLAGS
:*.. : :: * : : * *
MLBr_02041|M.leprae_Br4923 LDAAMIALPVETAGIAEIPIYDEDFVLALPPGHPLSGKRRVPTTALA--Q
MAV_2838|M.avium_104 LDAALIALPAETAGVTAIPIYDEDFVLALPPGHPLAGKRRVPATALA--D
MUL_2998|M.ulcerans_Agy99 LDTALIALPADYGGLTEIPIYEEDFVLALPPGHPMADRHGVPVAALS--E
Mflv_2332|M.gilvum_PYR-GCK SELGLIHLPATDKRLRHRVVASYQGGVAVRFDDPLAAKDLVSIEELRDRE
Mvan_4315|M.vanbaalenii_PYR-1 AELGLIHLPANDKRLRYKVVASYQGGIAVRFDDPLAAKDLVSIEELRDRE
MSMEG_1902|M.smegmatis_MC2_155 LDIGLIHLPSADKRLRHRVVARYQGAIAVRFDDPLAAKDVVAIEELRDRE
MAB_2764c|M.abscessus_ATCC_199 IDLGVSRVPAASARVQARLLNTERLAILADAS-AFPAKVSVQLADLRGYT
: .: :* : : : . .:. : * *
MLBr_02041|M.leprae_Br4923 LPLLLLDEGHCLRDQTLDICRKSGVQ--AELANTRAASLATAVQCVTGGL
MAV_2838|M.avium_104 LPLLLLDEGHCLRDQALDVCHKAGVR--AELANTRAASLATAVQCVTGGL
MUL_2998|M.ulcerans_Agy99 LPLLLLDEGHCLRDQALDVCQNAGVR--AEHADTRADSLATAVQCVNGGL
Mflv_2332|M.gilvum_PYR-GCK VAIDFARPNPVVLAGLTRRLNRKGVHHIVRTTNQRGGEVEMATQVFNRHL
Mvan_4315|M.vanbaalenii_PYR-1 VAIDVARPNPVVLAGLTRGLNRKGVHRIVRTTNQRGGEVEMATQVFNRHL
MSMEG_1902|M.smegmatis_MC2_155 VVIDFARPNPVVLAGLTRGLNAKGVTKIVRAINQLGGELEMATQVFNRHL
MAB_2764c|M.abscessus_ATCC_199 YVHGPEAWEIASMLEAQHVLFDSGVLN--DSLTRCDDVSSMLLTLRNSTK
** .
MLBr_02041|M.leprae_Br4923 G--VTLLPQSAAPVESVRSKLGLAQFAAPCPG-RRIGLAFRSASGRSAS-
MAV_2838|M.avium_104 G--VTLIPQSAVPVEASRSRLGLAQFAAPRPG-RRIGLVFRSSSGRDDS-
MUL_2998|M.ulcerans_Agy99 G--VTLIPQSAVSVEAARSRVGLTHFAAPTPG-RRIGLVYRASSGRDEA-
Mflv_2332|M.gilvum_PYR-GCK VAVVSYAPESFIGKIFSPPEFKLIPVDESTWAPAEIALAWVPERVQGR--
Mvan_4315|M.vanbaalenii_PYR-1 VAVVSYAPDSFIGKIFSPPEFKLIPLDESTWAPAEIALAWVPERVQAR--
MSMEG_1902|M.smegmatis_MC2_155 VAMVTYAPESMIGRIFSPPEFKLIPIDEATWAPAQIALAWAPDRLSDRRS
MAB_2764c|M.abscessus_ATCC_199 ITLRSLQSEELKG--LDPAEFVLLPIDDLTVE-IPTMLQWRAEDVDRLP-
: .:. ... * . * : .
MLBr_02041|M.leprae_Br4923 -----YRQIAKIIGELISTEHHVRLVA
MAV_2838|M.avium_104 -----YRELAGLIGELISSQHQVRLVK
MUL_2998|M.ulcerans_Agy99 -----YRQLAAIMGESISNEQQVRLVN
Mflv_2332|M.gilvum_PYR-GCK -----LAEVELMVEQIADRLGPVHRGA
Mvan_4315|M.vanbaalenii_PYR-1 -----LTEVELMVEQIADRLGPVHRGA
MSMEG_1902|M.smegmatis_MC2_155 ERVLRPAEIEALVDELERAVARPAGGA
MAB_2764c|M.abscessus_ATCC_199 --------IAEAIKSITAAVAGDRLGD
: : .