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VRVRLRATATAAVCSVCIAASVSVPTIQTLSASPEQHRTVSTQAYVLTSNDGTLSPASIGSLAALPGVTT AAAPTPPEGSTWPSANPLVNLAVGPLQFDPKFSRSPVLASPFTIVNAPFQLLTGQSIVNPNGTTSAPTVQ NLINAETTALGLLAGVPAAYVANTIAVVQAIAQNPGSLLPSGLVPTATTLSAANTTAVSPTTKTLASTAV TASAATAPAPTAPAGSTWPSTNPVVNLLVGPLQFNSKWQSPVLASPFTIVNAPFQLLTGQSIVNPDGTTV APTVQNFIAAETKAFGLLVGLPGAYVANTIAVVTALSQNPGSILPSGLIQPATTTANPTVAKTTALSLPE SSTTATSTTANTLAAPTASAPTGSAVTAPAPTAPAGSTWPSTNPVVNLLVGPLQFNSKWQSPVLASPFTI VNAPFQLLTGQSIVNPDGTTSAPTIQNLINAEAKAFGLLVGLPGAYVSNTIAVVTALTQNPASLLPAGLS APAATTTATSVKAPTSILSALSKTSTTAAKTATAEQKTAVEGTKAAESKATTSKSSPEAEPAKAGATKPA TPAEAVTPAEPAKPAEPAKSATPAEPVKAAEPAKPATPADAATPAEPAKPATAADAAAKPVDAAKPAEPK VNVPKVKLPTPVTKVGEVSGGVAPKTDDSAKADKSEKTDSKTDKADKGSTPKKPEKDSSPAKKPEAAASS STKSESGSSSSSSDSHAGSSNGSSSSGSSSSGSSHSDSHKASRN
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_0978 | - | - | 100% (744) | hypothetical protein MAB_0978 |
M. abscessus ATCC 19977 | MAB_0974 | - | 2e-23 | 25.51% (639) | hypothetical protein MAB_0974 |
M. abscessus ATCC 19977 | MAB_4293 | - | 3e-13 | 27.68% (271) | putative Fe-S oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3909c | - | 3e-15 | 28.96% (183) | hypothetical protein Mb3909c |
M. gilvum PYR-GCK | Mflv_3378 | - | 2e-10 | 28.30% (212) | hypothetical protein Mflv_3378 |
M. tuberculosis H37Rv | Rv3879c | - | 3e-15 | 28.96% (183) | hypothetical protein Rv3879c |
M. leprae Br4923 | MLBr_01022 | rpoT | 1e-06 | 23.83% (214) | RNA polymerase sigma factor |
M. marinum M | MMAR_5455 | - | 2e-14 | 28.17% (213) | hypothetical protein MMAR_5455 |
M. avium 104 | MAV_4817 | - | 4e-12 | 31.53% (222) | ferredoxin, 4Fe-4S |
M. smegmatis MC2 155 | MSMEG_0690 | - | 5e-15 | 33.04% (230) | iron-sulfur cluster-binding protein |
M. thermoresistible (build 8) | TH_3373 | - | 2e-10 | 26.15% (218) | PUTATIVE hypothetical protein Mjls_1192 |
M. ulcerans Agy99 | MUL_0574 | - | 5e-13 | 28.87% (239) | iron-sulphur-binding reductase |
M. vanbaalenii PYR-1 | Mvan_0619 | - | 2e-12 | 29.78% (272) | hypothetical protein Mvan_0619 |
CLUSTAL 2.0.9 multiple sequence alignment Mb3909c|M.bovis_AF2122/97 ----------------------------------MSITRPTGSYARQMLD Rv3879c|M.tuberculosis_H37Rv ----------------------------------MSITRPTGSYARQMLD MMAR_5455|M.marinum_M ----------------------------------MGIPRPTGEYAGRMLE MAV_4817|M.avium_104 -MTTQMLIRLVVGMGMTLIVAALAARRVLWLFKLITSGKPAP---GHTDD MUL_0574|M.ulcerans_Agy99 -MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQPAS---GRTDD MSMEG_0690|M.smegmatis_MC2_155 MAHTLEVSRLIIGLLMTAIVLVFAAKRVLWLTKLIRSGQKTLDENGRKND Mvan_0619|M.vanbaalenii_PYR-1 -MDTQMLIRIVVGVLMIAVVGVFAVKRVLWLTTLIRSGQPMSEGNNRKDH TH_3373|M.thermoresistible__bu -----------------------------------------------MAD MAB_0978|M.abscessus_ATCC_1997 ----------------------------------------------MRVR Mflv_3378|M.gilvum_PYR-GCK ------------------------------------MHSALRPYVTTGLA MLBr_01022|M.leprae_Br4923 ---------------------------------------------MEQSR Mb3909c|M.bovis_AF2122/97 PGGWVEADEDTFYDRAQEYSQVLQRVTDVLDTCRQQKGHVFEGGLWSGGA Rv3879c|M.tuberculosis_H37Rv PGGWVEADEDTFYDRAQEYSQVLQRVTDVLDTCRQQKGHVFEGGLWSGGA MMAR_5455|M.marinum_M AGGWPDADEDIHYDRAREYNRVLHLFTDVMDACRHQQVEVFDGGVWSGGA MAV_4817|M.avium_104 PGKRVWAEVSEVFGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF MUL_0574|M.ulcerans_Agy99 IGARIWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLF MSMEG_0690|M.smegmatis_MC2_155 LQKRITTQITEVFGQTRLLRWSVPGIAHFFTMWGFFVLASVYLEAYGVLF Mvan_0619|M.vanbaalenii_PYR-1 LKQRITTQFEEVFGQTRLLRWSVPGIAHFFTMWGFFVLATVYIEAFGQLV TH_3373|M.thermoresistible__bu FGRWNPNWNPDDGGQ--------PSLQDIHRSEQFIEALSTGRPVYANDP MAB_0978|M.abscessus_ATCC_1997 LRATATAAVCSVCIAASVSVPTIQTLSASPEQHRTVSTQAYVLTSNDGTL Mflv_3378|M.gilvum_PYR-GCK LVGTSVIALAPIAPPAPAFGGATVAKQVTQDVTLSARVVTLNPTPDALEM MLBr_01022|M.leprae_Br4923 RVPPLQWLSAVARPIARVLTLISTPTFDIADTFGYACPNPPEVSPTEGVY Mb3909c|M.bovis_AF2122/97 ANAANGALGANINQLMTLQDYLATVITWHRHIAGLIEQAKSD-------- Rv3879c|M.tuberculosis_H37Rv ANAANGALGANINQLMTLQDYLATVITWHRHIAGLIEQAKSD-------- MMAR_5455|M.marinum_M ASAANGALGGNLEQMSTLQDYLATVITWHQHVAGLIAEAKAN-------- MAV_4817|M.avium_104 QDNFHIPIIGRWDALGFLQDFFATAVFLGIATFAVIRSMRSPREIGRSSR MUL_0574|M.ulcerans_Agy99 VENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASR MSMEG_0690|M.smegmatis_MC2_155 DPEFHIPFIGRWPVLGFLQDFFAVAVLLGIIVFAIIRVVREPKKIGRDSR Mvan_0619|M.vanbaalenii_PYR-1 DHDFHIPLVGRWDALGFLQDFFAVAVLLGIITFAIIRIVREPKKHGRDSR TH_3373|M.thermoresistible__bu GEDELAYLMAGWRDRARNAPMRATITEQDAVAALQRGLPRPRG------- MAB_0978|M.abscessus_ATCC_1997 SPASIGSLAALPGVTTAAAPTPPEGSTWPSANPLVNLAVGPLQ------- Mflv_3378|M.gilvum_PYR-GCK GEQLQGSICGGNGTPCYEVEYAPIWTGPGYFGLGVEALREALTG------ MLBr_01022|M.leprae_Br4923 VVATKTSPATGQPVKRTATKTPATPAKRSTTKAANGSAPTKR-------- . Mb3909c|M.bovis_AF2122/97 -IGNNVDGAQREIDILENDPSLDADERHTAINSLVTATHGANVSLVAETA Rv3879c|M.tuberculosis_H37Rv -IGNNVDGAQREIDILENDPSLDADERHTAINSLVTATHGANVSLVAETA MMAR_5455|M.marinum_M -IDNNVDGAHREIRVLEGNADLDPEERKAAIASLIRSAHEANSGLVAEAA MAV_4817|M.avium_104 FYGSHTGGAWLVLFMIFNVIWTYVLVRGSAVNNG--TLPYGKGAFLSQLF MUL_0574|M.ulcerans_Agy99 FYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVNNE--TLPYGKGAFLSQLF MSMEG_0690|M.smegmatis_MC2_155 FYGSHTGGAWEILFMIFLVIATYALFRGAAVNTLGERFPYQSGAFFSDFM Mvan_0619|M.vanbaalenii_PYR-1 FYGSHTGGAWLILFMIFNVIWTYALVRGAGANTG--ALPYGNGAFFSQFM TH_3373|M.thermoresistible__bu --GAPRPGRRFSLTVVGSAAAAVICLGGFGALVAGAGPGDPLYGLRTMLF MAB_0978|M.abscessus_ATCC_1997 FDPKFSRSPVLASPFTIVNAPFQLLTGQSIVNPNGTTSAPTVQNLINAET Mflv_3378|M.gilvum_PYR-GCK NPGEETTIFAFSEGAVVASQWLEKHLEDPEAYPAPENLTFVVIGNPARKY MLBr_01022|M.leprae_Br4923 -ATSTASRATKSTTPPKASGASDAAKKARTSVKSVDTKAPSAQDHTTKAS Mb3909c|M.bovis_AF2122/97 ERVLESKNWKPPKN-ALEDLLQQKSPPPPDVPTLVVPSPGTPG--TPGTP Rv3879c|M.tuberculosis_H37Rv ERVLESKNWKPPKN-ALEDLLQQKSPPPPDVPTLVVPSPGTPG--TPGTP MMAR_5455|M.marinum_M EQVLASRNWKPPHN-ALKDLLHQVTPPAPGIPSVTVPTPGQPAPRPPGPK MAV_4817|M.avium_104 GAILRPLGQPANEY-IETAALLAHIAVMLAFLIIVLHSKHMHIFTAPINV MUL_0574|M.ulcerans_Agy99 AAILRPLGQPANEI-IETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINV MSMEG_0690|M.smegmatis_MC2_155 AWILRPLGATANMW-IETVALMGHIGVMLVFLLIVLHSKHLHIGLAPINV Mvan_0619|M.vanbaalenii_PYR-1 GWIMHPLGEPANEW-IETLALLAHIAIMLVFLLIVLHSKHLHIGLAPINV TH_3373|M.thermoresistible__bu GDVVRDDPVVLAAQ-TQLAEVEQLIAQGDWEAAQERLQAVTTTVATVGDE MAB_0978|M.abscessus_ATCC_1997 TALGLLAGVPAAYV-ANTIAVVQAIAQNPGSLLPSGLVPTATTLSAANTT Mflv_3378|M.gilvum_PYR-GCK GGSGTIWGRQWPTSPYQVIDVAQQYDPTVDMPVNNLNVLATLNATMGFFT MLBr_01022|M.leprae_Br4923 AAKDTLNDPEATLNTLDSDATADDLDAEPDLDVEPSEDIDIDIEAADLGL Mb3909c|M.bovis_AF2122/97 GTPITPGTPITPGTPITPGTPITP--GTPITPIPGAPVTPITP------- Rv3879c|M.tuberculosis_H37Rv ---------------ITPGTPITP--GTPITPIPGAPVTPITP------- MMAR_5455|M.marinum_M PFEPTPVNPHKPVTPGGPGTPVNPKPGAPVVPTPGGPTHPVTPGIPGTPG MAV_4817|M.avium_104 IFKRLPNGLGPLLPIEYDGKPIDFENPPDDAVFGRGKVEDFSWKAMLDFA MUL_0574|M.ulcerans_Agy99 TFKRLPDGLGPLLPVEADGKPVDFENPPDDAIFGRGKIEDFTWKGMLDFA MSMEG_0690|M.smegmatis_MC2_155 TFKRLPNGLGPLLPMESNGEYIDFEDPAEDAVFGKGKIEDFTWKGYLDFT Mvan_0619|M.vanbaalenii_PYR-1 TFKRMPNALGPLLPVEYKGELVDFEDPAEDAVLGRGKIEDFTWKAYLDMT TH_3373|M.thermoresistible__bu TRKQELVAEWQELSVKVESRNPDATVPPDAPPVTLPVIDPATS------- MAB_0978|M.abscessus_ATCC_1997 AVSPTTKTLASTAVTASAATAPAPTAPAGSTWPSTNPVVNLLVGPLQFNS Mflv_3378|M.gilvum_PYR-GCK NHLGRGYSDVDIDDPANSRWEEDGIEYVFVPAKTLPLVEPLRWVGLGQLA MLBr_01022|M.leprae_Br4923 DDLEDDDVVTDIEPGETEDGEATAATKTDEASTD---------------- Mb3909c|M.bovis_AF2122/97 ------TPGTPVTP---VTPGKPVTPVTPVKPGTPGEP-TPITPVTPPVA Rv3879c|M.tuberculosis_H37Rv ------TPGTPVTP---VTPGKPVTPVTPVKPGTPGEP-TPITPVTPPVA MMAR_5455|M.marinum_M TPGIPGIPGTPITPGTPITPGKPVTPVTPGKP-KPGKPDTPVLPVEPTPA MAV_4817|M.avium_104 TCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGDKQSPLE MUL_0574|M.ulcerans_Agy99 TCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEKTADLL MSMEG_0690|M.smegmatis_MC2_155 TCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHMFAKAPYILGEKPSPLE Mvan_0619|M.vanbaalenii_PYR-1 TCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHLFAKAPYILGDKETPLE TH_3373|M.thermoresistible__bu -------TEPTEPGTPSTEPAEPGEPTEPGDPDMPVDGTEPTSPGTEPTA MAB_0978|M.abscessus_ATCC_1997 KWQSPVLASPFTIVNAPFQLLTGQSIVNPDGTTVAPTVQNFIAAETKAFG Mflv_3378|M.gilvum_PYR-GCK DELTPGLQYLIEQGYNRDDRITGTTIDAPEKSWSYAPINFLEAIANIPYY MLBr_01022|M.leprae_Br4923 ---------------------DDEEIVEPTEKDKASGDFVWDEDESEALR Mb3909c|M.bovis_AF2122/97 P-------------------ATPATPATPVTPAPAPHPQPAPAPAPS--- Rv3879c|M.tuberculosis_H37Rv P-------------------ATPATPATPVTPAPAPHPQPAPAPAPS--- MMAR_5455|M.marinum_M P-------------------APAPAPAPAPAPAPAPAPAPAPAPQPAPAP MAV_4817|M.avium_104 STPEGGVGEELSGEKHA---EAHHVPESGFGRVMGSGPEQATRPLVGTEE MUL_0574|M.ulcerans_Agy99 ---EGLDLETAAG-------EGHHVPESGFGRVPGDGPEQAARPLVGTAE MSMEG_0690|M.smegmatis_MC2_155 STPEGGLGEKARGEKHEQKHAHDHVPESGFERILGSGPEQALRPLVGTEE Mvan_0619|M.vanbaalenii_PYR-1 NTPEGGLGEELRGEKQSEEHSHEHVPESGFERIMGSGPEQATRPLVGTLE TH_3373|M.thermoresistible__bu G-----------------------PDQPTVPPTVGPTSEPATSEP----- MAB_0978|M.abscessus_ATCC_1997 ----------------------LLVGLPGAYVANTIAVVTALSQNPGSIL Mflv_3378|M.gilvum_PYR-GCK S---------------------VAGTNRFANAMRASGSWWVYTPTNVLGW MLBr_01022|M.leprae_Br4923 Q------------------------ARKDAELTASADSVRAYLKQIG--- . Mb3909c|M.bovis_AF2122/97 -PGPQP--------VTPATPGPSGPATPGTPGGEPAPHVKPAALAEQPGV Rv3879c|M.tuberculosis_H37Rv -PGPQP--------VTPATPGPSGPATPGTPGGEPAPHVKPAALAEQPGV MMAR_5455|M.marinum_M GPGPQPGPADPGASPQPAPSQPGSPSTPGQPSTDPA-HVKPAAATETSTA MAV_4817|M.avium_104 QGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEFPSE MUL_0574|M.ulcerans_Agy99 QGGVIDPDVLWSCVSCGACVEQCPVDIEHIDHIVDMRRYQVMMESEFPSE MSMEG_0690|M.smegmatis_MC2_155 QGGVIDPDVLWSCTNCGACVEQCPVDIEHIDHIVDMRRYQVMVESEFPGE Mvan_0619|M.vanbaalenii_PYR-1 QGGVIDPDVLWSCTTCGACVEQCPVDIEHIDHIVDMRRYQVMMESEFPGE TH_3373|M.thermoresistible__bu --------------AMTAPTTTVPTSAPGSAVRTTTSAPTTATTTSGSTT MAB_0978|M.abscessus_ATCC_1997 PSGLIQPATTTANPTVAKTTALSLPESSTTATSTTANTLAAPTASAPTGS Mflv_3378|M.gilvum_PYR-GCK DPANPEMTRAFVDFLVAIPSISTPMGMTADWWARANLPMNEGCTGFPPCD MLBr_01022|M.leprae_Br4923 ------------------KVALLNAEEEVELAKRIEAGLYATQLMTELSE Mb3909c|M.bovis_AF2122/97 PGQHAGGGTQSGPAHADESAAS--VTPAAASGVPG-ARAAAAAP------ Rv3879c|M.tuberculosis_H37Rv PGQHAGGGTQSGPAHADESAAS--VTPAAASGVPG-ARAAAAAP------ MMAR_5455|M.marinum_M PSTQPSG--PSGPAHGDDSSGGG-AAAPAASAMPGGGRGVSAGS------ MAV_4817|M.avium_104 LSVLFKNLETKANPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYEYLF MUL_0574|M.ulcerans_Agy99 LSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYEYLF MSMEG_0690|M.smegmatis_MC2_155 LGVLFKNLETKGNPWGQNAKDRTNWIDEVDFDVPVYGEDVDSFDGFEYLF Mvan_0619|M.vanbaalenii_PYR-1 LGVLFKNLETKGNPWGQNAKDRTNWIDEVDFDVPVYGKDVESFDGFEYLF TH_3373|M.thermoresistible__bu AGPTAGGPTSSGPATGPTSVPRE--------------------------- MAB_0978|M.abscessus_ATCC_1997 AVTAPAPTAPAGSTWPSTNPVVNLLVGPLQFN------------------ Mflv_3378|M.gilvum_PYR-GCK NPAGITDQMFKVQLWDFFAPGGFTFTDPITPEYNPISDTEAFWG-----Q MLBr_01022|M.leprae_Br4923 RGTKLPTAQRRDMMWICRDGDR---------------------------- Mb3909c|M.bovis_AF2122/97 SGTAVGAGARSSVGTAAASGAGSHAATGRAPVATSDKAAAPST--RAASA Rv3879c|M.tuberculosis_H37Rv SGTAVGAGARSSVGTAAASGAGSHAATGRAPVATSDKAAAPST--RAASA MMAR_5455|M.marinum_M SSGLSSAGASSSTSQSAASGAGSRAASGRAPVESGGRGPNTAAP-RPAAA MAV_4817|M.avium_104 WVGCAGAYDDKAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSA-RRSGN MUL_0574|M.ulcerans_Agy99 WVGCAGAYDDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSA-RRSGN MSMEG_0690|M.smegmatis_MC2_155 WVGCAGAYEDRAKKTTKAVAELLATAGVKFLVLGTGETCTGDSA-RRSGN Mvan_0619|M.vanbaalenii_PYR-1 WVGCAGAYEDRAKKTTKAVAELLAAAGVKYLVLGEGETCNGDSA-RRSGN TH_3373|M.thermoresistible__bu ----PGAGAGTTEPTAPAARAGEDGVGGDGTVGGDG-------------- MAB_0978|M.abscessus_ATCC_1997 ----SKWQSPVLASPFTIVNAPFQLLTGQSIVNPDGTTSAPTIQNLINAE Mflv_3378|M.gilvum_PYR-GCK ELGLTGDKVEWYGETVHPEPFGETKGFLDFLISTPEGIKTPTLQDQLNAF MLBr_01022|M.leprae_Br4923 ----AKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIR------ : Mb3909c|M.bovis_AF2122/97 RTAPPARP-PSTDHIDKPDRSESADDGTPVSMIPVSAARAARDAATAAAS Rv3879c|M.tuberculosis_H37Rv RTAPPARP-PSTDHIDKPDRSESADDGTPVSMIPVSAARAARDAATAAAS MMAR_5455|M.marinum_M RTASPTRPAPERPKPDEKEKSEAPDAVTPSPMVPVSAARAARDAIASAS- MAV_4817|M.avium_104 EFLFQQLAAQAVETLDGVFEGVETVDRKIVVTCPHCFNTLGREYRQLGAN MUL_0574|M.ulcerans_Agy99 EFLFQQLAQQAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLGSN MSMEG_0690|M.smegmatis_MC2_155 EFLFQQLAAQNVETINELFEGVETVDRKIVVTCPHCFNTIGREYPQLGAN Mvan_0619|M.vanbaalenii_PYR-1 EFLFQQLAAQNVETLGELFEGVERVDRKVVVTCPHCFNTLGREYPQLGGN TH_3373|M.thermoresistible__bu ------------AFAEETVGEVPQLTATTTVVLPQSGAADAAGD------ MAB_0978|M.abscessus_ATCC_1997 AKAFGLLVGLPGAYVSNTIAVVTALTQNPASLLPAGLSAPAATTTATSVK Mflv_3378|M.gilvum_PYR-GCK RNLADGLTTTWNPFVPKSYVWNPDMTPFAYLARPLAKILCPTCNAVDPFM MLBr_01022|M.leprae_Br4923 --------------AVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTI Mb3909c|M.bovis_AF2122/97 ARQRGRGDALRLARRIAAALNASDN----------NAGDYGFFWITAVTT Rv3879c|M.tuberculosis_H37Rv ARQRGRGDALRLARRIAAALNASDN----------NAGDYGFFWITAVTT MMAR_5455|M.marinum_M -RRSQKKDPLRLARRIAAALNAPDTY---------NKGDYGFFWITAVTT MAV_4817|M.avium_104 YTVLHHTQLLNRLIRDNKLVPVTPVS----QDITYHDPCYLGRHNKVYEA MUL_0574|M.ulcerans_Agy99 YSVLHHTQLLNRLIRDKKLVPVTPVS----QDVTYHDPCYLGRHNKVYEA MSMEG_0690|M.smegmatis_MC2_155 YSVVHHTQLLNRLVRDKKLVPVKSVSEQNGQPVTYHDPCFLGRHNKVYEA Mvan_0619|M.vanbaalenii_PYR-1 YTVLHHTQLLNRLVRDKKLVPVKSTD--NGQDITYHDPCYLGRHNKEYSA TH_3373|M.thermoresistible__bu -------------------------------------------------- MAB_0978|M.abscessus_ATCC_1997 APTSILSALSKTSTTAAKTATAEQKT------AVEGTKAAESKATTSKSS Mflv_3378|M.gilvum_PYR-GCK PEDWKVGLDVYPGAYIPPSVKDQYDP---------ETGKYIGDPVDGLTD MLBr_01022|M.leprae_Br4923 RIPVHMVEVINKLGRIQRELLQDLGR------------------------ Mb3909c|M.bovis_AF2122/97 DGSIVVANSYGLAYIP-----------------DGMELPNKVYLASADHA Rv3879c|M.tuberculosis_H37Rv DGSIVVANSYGLAYIP-----------------DGMELPNKVYLASADHA MMAR_5455|M.marinum_M DGDIVVANSYGLAYIP-----------------ENVELPHKVYMASADHA MAV_4817|M.avium_104 PRELIGAAGANLTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEA MUL_0574|M.ulcerans_Agy99 PRELIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEA MSMEG_0690|M.smegmatis_MC2_155 PRELVEASGVTLKEMPRHADRGLCCGAGGARMWMEEHIGKRVNVERTEEA Mvan_0619|M.vanbaalenii_PYR-1 PRELIGASGATLTEMPRHADRGLCCGAGGARMWMEEHIGKRVNTERTEEA TH_3373|M.thermoresistible__bu -------------------------------------------------- MAB_0978|M.abscessus_ATCC_1997 PEAEPAKAGATKPATP-------------AEAVTPAEPAKPAEPAKSATP Mflv_3378|M.gilvum_PYR-GCK AEIAEWNEKAGLNDIVDETTDG--------TEETEESGDVSEDPADADTS MLBr_01022|M.leprae_Br4923 -----------------------------------EPTPEELAKEMDITP Mb3909c|M.bovis_AF2122/97 IPVDEIARCATYPVLAVQAWAAFHDMTLRAVIGTAEQLASSDPGVAKIVL Rv3879c|M.tuberculosis_H37Rv IPVDEIARCATYPVLAVQAWAAFHDMTLRAVIGTAEQLASSDPGVAKIVL MMAR_5455|M.marinum_M IPADEQARFATYPVLAVQGWAAFHDLKLRAVIGTAEQLANSDAGAAKIIL MAV_4817|M.avium_104 LATGAATVATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQILLGSLEY MUL_0574|M.ulcerans_Agy99 VATNASTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGSLDR MSMEG_0690|M.smegmatis_MC2_155 MDT-ASTIATGCPFCRVMITDGVDDVAASRNVEKAEVLDVAQLLLNSLDT Mvan_0619|M.vanbaalenii_PYR-1 IDTGASAIATGCPFCRVMMTDGVDDVSAAREIEKVEVLDVAQLLLGSLDQ TH_3373|M.thermoresistible__bu -------------------------------------------------- MAB_0978|M.abscessus_ATCC_1997 AEPVKAAEPAKPATPADAATPAEPAKPATAADAAAKPVDAAKPAEPKVNV Mflv_3378|M.gilvum_PYR-GCK LLSARSMATVDESSEDTGASDKKTDVISAAVQDLVDTFDKTPAAEDTEQG MLBr_01022|M.leprae_Br4923 EKVLEIQQYAREPISLDQTIGDEGDSQLGDFIEDSEAVVAVDAVSFTLLQ Mb3909c|M.bovis_AF2122/97 EPDDIPESGKMTGRSRLEVV--------DPSAAAQLADTTDQRLLDLLPP Rv3879c|M.tuberculosis_H37Rv EPDDIPESGKMTGRSRLEVV--------DPSAAAQLADTTDQRLLDLLPP MMAR_5455|M.marinum_M EADDIPESGKMTGRPRLEVV--------DPSAAAQLAETEDLRLLELLPP MAV_4817|M.avium_104 DKATLPEKGTAAKEAEKRAA-----QAPKATATVEAPAKETTKEPAEAAP MUL_0574|M.ulcerans_Agy99 EKATLPEKGTAAKEAEKRAK-----TAPKAAAP-AAPAPAPAEAPAKAAE MSMEG_0690|M.smegmatis_MC2_155 SKVTLPEKGTAAKESEKRAA-----ARAEAEAKAEAAAPPVEEAAPEAEA Mvan_0619|M.vanbaalenii_PYR-1 SSFTLPEKGTAAKEAEERAARVAAQAPAKAEESAIETEAEAKTAAEPAEA TH_3373|M.thermoresistible__bu -------------------------------------------------- MAB_0978|M.abscessus_ATCC_1997 PKVKLPTPVTKVGEVSGGVAP------KTDDSAKADKSEKTDSKTDKADK Mflv_3378|M.gilvum_PYR-GCK AETPAGSEEPTQPQDETPAADADDDAGVDAEPVTTPRKPSSTTKSDVDAS MLBr_01022|M.leprae_Br4923 DQLQSVLETLSEREAG----------------VVRLRFGLTDGQPRTLDE Mb3909c|M.bovis_AF2122/97 APVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAY-------AA Rv3879c|M.tuberculosis_H37Rv APVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAY-------AA MMAR_5455|M.marinum_M APADANPPDDERHMFWFDLMKPMTSNATGREVAHLRAFRAY-------AE MAV_4817|M.avium_104 KAEAAPAA-PAAPVKGLGIAGGAKRPGAKKSAPAAEAKTEAPAEAKTEAP MUL_0574|M.ulcerans_Agy99 ASAAATAASPAAPAKGLGMAGGAKRPGAKKAAPAPAAETAA-----AEAP MSMEG_0690|M.smegmatis_MC2_155 PAAPAAGGAEAKPVTGLGMAGAAKRPGAKKAAPAAEASAAPA------AA Mvan_0619|M.vanbaalenii_PYR-1 AKSTAAADTESKPVTGLGLAGGAKRPGAKKPAAAEPAEDKP--------A TH_3373|M.thermoresistible__bu -------------------------------------------------- MAB_0978|M.abscessus_ATCC_1997 GSTPKKPEKDSSPAKKPEAAASSSTKSESGSSSSSSDSHAG-------SS Mflv_3378|M.gilvum_PYR-GCK ESADADATTSGTAGTSESSESEKSDTSSDSSASDSSASDSAS------SS MLBr_01022|M.leprae_Br4923 IGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD------------- Mb3909c|M.bovis_AF2122/97 HSQEIALHQAHTATDAAVQRVAVA-------------------------- Rv3879c|M.tuberculosis_H37Rv HSQEIALHQAHTATDAAVQRVAVA-------------------------- MMAR_5455|M.marinum_M HCQEIALHQAYSAADAEAQRPAVA-------------------------- MAV_4817|M.avium_104 AAPAKGLGIAAGAKRPGAKKSAP--------------------------- MUL_0574|M.ulcerans_Agy99 AAPAKGLGMAAGAKKPGAKKAAAP--------TGETKPAEAAAPAAPVKG MSMEG_0690|M.smegmatis_MC2_155 PAPAKGLGLAGGAKRPGAKKAA-------APAAE--APAAPASDAPPVKG Mvan_0619|M.vanbaalenii_PYR-1 PAPAKGLGIAGGAKRPGAKKAAPAAGTTPAPAAESAAAAEPAKAEPEVKG TH_3373|M.thermoresistible__bu -------------------------------------------------- MAB_0978|M.abscessus_ATCC_1997 NGSSSSGSSSSGSSHSDSHKASRN-------------------------- Mflv_3378|M.gilvum_PYR-GCK DSSGSGAGSSGSGGSAGSGGGSDD-------------------------- MLBr_01022|M.leprae_Br4923 -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 -DWLYWQYVTGLLDRALAAAS----------------------------- Rv3879c|M.tuberculosis_H37Rv -DWLYWQYVTGLLDRALAAAC----------------------------- MMAR_5455|M.marinum_M -DWLYWRYVAGLLANALADAS----------------------------- MAV_4817|M.avium_104 --AAQAPKTEAPKTEAPKTEAKTEAAG-------EAKTEAPAAPAAP--- MUL_0574|M.ulcerans_Agy99 LGMASGAKRPGAKKAAPPAAAAPEAAATAPAPEAAAAPAEPAAPAAP--- MSMEG_0690|M.smegmatis_MC2_155 LGLAGGAKRPGAKKTAAAAP--AEKPAATEAPEASATPAAPAAP------ Mvan_0619|M.vanbaalenii_PYR-1 LGIAGGAKRPGAKKQAAPAAPAAAAPAATPAPEAPAQPEAAAAAPAKPEP TH_3373|M.thermoresistible__bu -------------------------------------------------- MAB_0978|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_3378|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01022|M.leprae_Br4923 -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 -------------------------------------------------- Rv3879c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5455|M.marinum_M -------------------------------------------------- MAV_4817|M.avium_104 -VKGLGIAAGAKRPGAKKAAPKAEAPKAEAEAAKAEAPKPEAPKAEAESK MUL_0574|M.ulcerans_Agy99 -VKGLGIATGAKRPGAKKAPARAEAPSAAAPAQ---------PEPEATPE MSMEG_0690|M.smegmatis_MC2_155 -VKGLGLAAGAKRPGAKKTAAAPAEKPAAAETEAPAPAETAAPAEPAKPE Mvan_0619|M.vanbaalenii_PYR-1 EVKGLGIAAGARRPGAKKAPAAPAAESTSAPAESAPAPAESAPAPAATPE TH_3373|M.thermoresistible__bu -------------------------------------------------- MAB_0978|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_3378|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01022|M.leprae_Br4923 -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 -------------------------------------------------- Rv3879c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5455|M.marinum_M -------------------------------------------------- MAV_4817|M.avium_104 P---------------------------EPAKPSNGEGGSS--------- MUL_0574|M.ulcerans_Agy99 P---------------------------EPASKQDGEPTPP--------- MSMEG_0690|M.smegmatis_MC2_155 PPVVGLGIAAGARRPGAKKAAAKPAAAPAPAAEKPAEQAAEPEKPAEKPA Mvan_0619|M.vanbaalenii_PYR-1 P---------------------------EPAPEAPSSGASD-----NGDT TH_3373|M.thermoresistible__bu -------------------------------------------------- MAB_0978|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_3378|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_01022|M.leprae_Br4923 -------------------------------------------------- Mb3909c|M.bovis_AF2122/97 ------------------------ Rv3879c|M.tuberculosis_H37Rv ------------------------ MMAR_5455|M.marinum_M ------------------------ MAV_4817|M.avium_104 --KPSQPPVKGLGIARGARPPGKR MUL_0574|M.ulcerans_Agy99 --AAPAAPVKGLGMARGARPPGKR MSMEG_0690|M.smegmatis_MC2_155 EPEKPEPPVVGLGIKPGAKRPGKR Mvan_0619|M.vanbaalenii_PYR-1 RVVGDEPPVKGLGIAKGARRPGKR TH_3373|M.thermoresistible__bu ------------------------ MAB_0978|M.abscessus_ATCC_1997 ------------------------ Mflv_3378|M.gilvum_PYR-GCK ------------------------ MLBr_01022|M.leprae_Br4923 ------------------------