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MPAPLQIRHFRESDVPDQTGKTHVITGANNGLGLVAAEALARAGARVVLACRNQQTGRAALDKVRALGPN ADHALVELDLTSLASVRSAADAIRTQAPTIDVLLNNAGVMAIPLQRTAEGFEMQIGVNHLGHFVLTDALL PSLLAADAPRVISLGSVAHAQGRNNLKVDDLNFTQRRYNRMTAYRASKLACMLFGSELARKAAAAGSSLV SVNVHPGVAATNLFDSMIPKLPGLHKAFYFGMGLVLQDERQGAESELYAASMPDVQPDDYLGPTQLTGAR GPVARAPRSKEARDPKLAAQLWQKSVELTGADYSRLSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2325 | - | - | 100% (318) | putative short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0643 | - | 2e-55 | 42.62% (305) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1144c | - | 7e-54 | 43.81% (299) | short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0069 | - | 2e-58 | 44.85% (301) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0151 | - | 1e-58 | 43.38% (302) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0068 | - | 4e-58 | 44.52% (301) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00315 | - | 8e-49 | 41.72% (302) | short chain dehydrogenase |
| M. marinum M | MMAR_0757 | - | 3e-59 | 46.08% (306) | dehydrogenase/reductase |
| M. avium 104 | MAV_4710 | - | 2e-60 | 45.71% (315) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0863 | - | 2e-62 | 45.72% (304) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_4179 | - | 8e-62 | 44.70% (302) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_1391 | - | 2e-58 | 45.42% (306) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0753 | - | 1e-62 | 45.54% (303) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0151|M.gilvum_PYR-GCK MTS------KWTAADVPDQSGRVAVVTGANTGIGYETAEVLAGKGARVVI
Mvan_0753|M.vanbaalenii_PYR-1 MSS------KWTAADVPDQSGRVAVVTGANSGIGYEAAAVLAGRGARVVV
TH_4179|M.thermoresistible__bu MTG------KWTARDVPDQTGRTAVITGANTGLGFETAKVLAEKGAHVVL
MSMEG_0863|M.smegmatis_MC2_155 MSAD----TKWTEADVPDQSGRVAIVTGSNTGLGYETARALAAKGAHVVI
Mb0069|M.bovis_AF2122/97 -------MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVL
Rv0068|M.tuberculosis_H37Rv -------MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVL
MLBr_00315|M.leprae_Br4923 -------MAKWTTADIPDQTGRVAVITGANTGLGYQTALALAEHGAHVVL
MMAR_0757|M.marinum_M MSANGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALAGRGAHVVL
MUL_1391|M.ulcerans_Agy99 MSAKGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAHVVL
MAV_4710|M.avium_104 MAPHDKRHRDWSEADVGDQSGRVVVITGANTGIGYETAAVLAHRGAHVVL
MAB_2325|M.abscessus_ATCC_1997 MPAP-LQIRHFRESDVPDQTGKTHVITGANNGLGLVAAEALARAGARVVL
.: *: **:*:. ::**:*.*:* :* .** **:**:
Mflv_0151|M.gilvum_PYR-GCK AVRDAGKGQKALDAITRKHPGAAVSLQELDLSSLGSVRRATDALRSAHPR
Mvan_0753|M.vanbaalenii_PYR-1 AVRNLDKGRQAVSRIRQLHPGADVMLQELDLSSLASVRAAADDLRAAHPR
TH_4179|M.thermoresistible__bu AVRDPDKGRRAADRITAAAPHADVTVRQLDLTSLDNIRRAADDLRAGYPR
MSMEG_0863|M.smegmatis_MC2_155 AVRNLDKGRDAVDRIMASTPKADLKLQKLDVGSLDSVRTAADELKGAYPH
Mb0069|M.bovis_AF2122/97 AVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQR
Rv0068|M.tuberculosis_H37Rv AVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQR
MLBr_00315|M.leprae_Br4923 AVRNLDKGKDAAARITATSAQNNVALQELDLASLESVRAAAKQLRSDYDH
MMAR_0757|M.marinum_M AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MUL_1391|M.ulcerans_Agy99 AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MAV_4710|M.avium_104 AVRDLEKGNAALSRIVAASPNADVTLQQLDLASLASVRSAAEALRAAYPR
MAB_2325|M.abscessus_ATCC_1997 ACRNQQTGRAALDKVRALGPNADHALVELDLTSLASVRSAADAIRTQAPT
* *: .*. * : . : **: ** .:* *: ::
Mflv_0151|M.gilvum_PYR-GCK IDLLINNAGVMYPPKQVTRDGFELQFGTNHLGHFAFTGLLLDNLLDVPGS
Mvan_0753|M.vanbaalenii_PYR-1 IDLLINNAGVMYPPKQTTSDGFELQFGTNHLGHFALTGLLLDRLLPVEGS
TH_4179|M.thermoresistible__bu IDLLINNAGVMYPPRQTTRDGFELQFGTNHLGHFALTGQLLDNILPVDGS
MSMEG_0863|M.smegmatis_MC2_155 IDLLINNAGVMYPPKQTTVDGFELQFGTNHLGPFALTGLLIDHLLPVEGS
Mb0069|M.bovis_AF2122/97 IDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGS
Rv0068|M.tuberculosis_H37Rv IDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGS
MLBr_00315|M.leprae_Br4923 IDLLINNAGVMWTPKSTTKDGFELQFGTNHLGHFAFTGLLLDRLLPIVGS
MMAR_0757|M.marinum_M IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MUL_1391|M.ulcerans_Agy99 IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MAV_4710|M.avium_104 IDLLINNAGVMWTPKQVTEDGFELQFGTNHLGHFALTGLLLDHLLGVRDS
MAB_2325|M.abscessus_ATCC_1997 IDVLLNNAGVMAIPLQRTAEGFEMQIGVNHLGHFVLTDALLPSLLAADAP
**:*:****** * . * :***:*:*.**** *.:*. *: :* .
Mflv_0151|M.gilvum_PYR-GCK RVVTVASLAHK-NLADIHFDDLQW-ERKYNRVAAYGQSKLANLMFTYELQ
Mvan_0753|M.vanbaalenii_PYR-1 RVVSVASIAHN-IQADIHFDDLQW-ERSYNRVAAYGQSKLANLMFTYTLA
TH_4179|M.thermoresistible__bu RVVTVASIAHR-NMADIHFDDLQW-ERGYHRVAAYGQSKLANLMFAYELQ
MSMEG_0863|M.smegmatis_MC2_155 RVVAVASVAHR-IRAKIHFEDLQW-ERRYNRVEAYGQSKLANLLFAYELQ
Mb0069|M.bovis_AF2122/97 RVVTISSVGHR-IRAAIHFDDLQW-ERRYRRVAAYGQAKLANLLFTYELQ
Rv0068|M.tuberculosis_H37Rv RVVTISSVGHR-IRAAIHFDDLQW-ERRYRRVAAYGQAKLANLLFTYELQ
MLBr_00315|M.leprae_Br4923 RVITVSSLSHR-LFADIHFNDLQW-ECNYNRVAAYGQSKLANLLFTYELQ
MMAR_0757|M.marinum_M RVITVSSLGHR-IRAAIHFDDLQW-ERSYNRVAAYGQSKLANLLFTYELQ
MUL_1391|M.ulcerans_Agy99 RVITVSSLGHR-IRAAIHFDDLQW-ERSYNRVAAYGQSKLANLLFTYELQ
MAV_4710|M.avium_104 RVVTVSSLGHR-LRAAIHFDDLHW-ERRYDRVAAYGQSKLANLLFTYELQ
MAB_2325|M.abscessus_ATCC_1997 RVISLGSVAHAQGRNNLKVDDLNFTQRRYNRMTAYRASKLACMLFGSELA
**:::.*:.* ::.:**:: : * *: ** :*** ::* *
Mflv_0151|M.gilvum_PYR-GCK RRLAARG-APTIAVAAHPGISNTELMR-HVPGT--SLPGVMKLAGLVTNT
Mvan_0753|M.vanbaalenii_PYR-1 RRLAAKG-APTIAVAAHPGISNTELMR-HIPGS--QLPGFAWLAGLVTNS
TH_4179|M.thermoresistible__bu RRLSAKN-APTISVAAHPGVSNTELTR-YIPGA--RLPGVSLLAGLLTNS
MSMEG_0863|M.smegmatis_MC2_155 RRLAAAG-KPTISVAAHPGLSNTELMR-HIPGT--GLPGYHQIASLFSNS
Mb0069|M.bovis_AF2122/97 RRLAPG--GTTIAVASHPGVSNTELVR-NMPRP--LVAVAAILAP-LMQD
Rv0068|M.tuberculosis_H37Rv RRLAPG--GTTIAVASHPGVSNTEVVR-NMPRP--LVAVAAILAP-LMQD
MLBr_00315|M.leprae_Br4923 RRLATR--QTTIAVAAHPGGSRTELTR-TLPAL--IAPIFSVAELFLTQD
MMAR_0757|M.marinum_M RRLAADSQAATIAVAAHPGGSNTELAR-NLPRM--LVPLANILGPALFQS
MUL_1391|M.ulcerans_Agy99 RRLAADSQAATIAVAAHPGDSNTELAR-NLPRM--LVPLANILGPALFQS
MAV_4710|M.avium_104 RRLAAAPDAKTIAVAAHPGGSNTELAR-HLPGI--FRPVQAVLGPVLFQS
MAB_2325|M.abscessus_ATCC_1997 RKAAAAG-SSLVSVNVHPGVAATNLFDSMIPKLPGLHKAFYFGMGLVLQD
*: :. ::* *** : *:: :* . :
Mflv_0151|M.gilvum_PYR-GCK PAVGALPTVRAATDPGVTGGQYYGPSGFNEMVGHPVLVTSNKKSHDVAVQ
Mvan_0753|M.vanbaalenii_PYR-1 PAVGSLATLRAATDPGVRGGQYYGPSGVRELVGHPVLVQSNRKSHDVDVQ
TH_4179|M.thermoresistible__bu PAVGALATLRAATDPEVKGGQYYGPDGFQEIRGHPVLVGSSAKSRDEDIQ
MSMEG_0863|M.smegmatis_MC2_155 PLMGALATLRAATDPGVKGGQYYGPDGFREVRGHPELVKSSSQSRDPELQ
Mb0069|M.bovis_AF2122/97 AELGALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQ
Rv0068|M.tuberculosis_H37Rv AELGALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQ
MLBr_00315|M.leprae_Br4923 AATGALPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSHDVDRQ
MMAR_0757|M.marinum_M AQMGALPTLRAATDPSVAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQ
MUL_1391|M.ulcerans_Agy99 AQMGALPTLRTATDPSAAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQ
MAV_4710|M.avium_104 PAMGALPTLRAATDPAVQGAQYYGPDGFLEQRGRPKLVESSAQSHDEQLQ
MAB_2325|M.abscessus_ATCC_1997 ERQGAESELYAASMPDVQPDDYLGPTQLTGARGPVARAPRSKEARDPKLA
*: . : :*: . . :* ** . * . . :::*
Mflv_0151|M.gilvum_PYR-GCK QRLWTVSEELTGVKYGV---
Mvan_0753|M.vanbaalenii_PYR-1 ERLWTVSEELTGVSYDL---
TH_4179|M.thermoresistible__bu RRLWTVSEELTGVTFPV---
MSMEG_0863|M.smegmatis_MC2_155 RRLWAVSEELTGVSYPV---
Mb0069|M.bovis_AF2122/97 RRLWAVSEELTGVVYPVG--
Rv0068|M.tuberculosis_H37Rv RRLWAVSEELTGVVYPVG--
MLBr_00315|M.leprae_Br4923 LRLWAVSEELTGVVYPVG--
MMAR_0757|M.marinum_M RRLWTVSEELTGVSFPV---
MUL_1391|M.ulcerans_Agy99 RRLWTVSEELTGVSFPV---
MAV_4710|M.avium_104 RRLWAVSEELTGVHFPV---
MAB_2325|M.abscessus_ATCC_1997 AQLWQKSVELTGADYSRLSG
:** * ****. :