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VSNTAVTAAAALSKDVSLIFFADLVILLVAALACGAVAGKIGLPKMVGEIAAGVLLGPTVFGRLFPETKD ALFPSAGTGSEIISGLCLLAVVLLVGVAGMHVDVDKLKQRLAGIATISVLGLAVPLAGGMAVGYLVPEPL RPAAVDRTVFALFLGTAVAVSAIPVIARILMDLGLASHEIAQVILAAAIVDDVAGWLLLSAVTGMASDSG TGGVAVLKMAVAAIVAVVALTALTRPALRNRLARRCSRWSAPTSTTVTVATIIVCATAGQLLGFEPVIGA FFAGILVIAATPAGSRVHKPLHAMAVAFFGPIFFATIGLQLDLGRLLSGPVLALTASICVVAVFSKFLGA GMGARISGFSWPESVAVGAGLNTRGVIQIVIAMVGVRCGVFSPEVFTALVVTTIATTAIAGPVLKRTLTP RRQLPAVISKPPQEPALNR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2285 | - | - | 100% (439) | Na+/H+ antiporter |
| M. abscessus ATCC 19977 | MAB_0385 | - | 1e-12 | 24.45% (409) | hypothetical protein MAB_0385 |
| M. abscessus ATCC 19977 | MAB_4717c | - | 1e-05 | 23.46% (422) | potassium/proton antiporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3264c | - | 1e-15 | 24.81% (403) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_0160 | - | 4e-07 | 23.70% (405) | potassium/proton antiporter |
| M. tuberculosis H37Rv | Rv3236c | - | 1e-15 | 24.81% (403) | integral membrane transport protein |
| M. leprae Br4923 | MLBr_00782 | - | 1e-14 | 24.02% (408) | putative transmembrane transport protein |
| M. marinum M | MMAR_3635 | - | 5e-70 | 39.80% (407) | integral membrane ion antiporter |
| M. avium 104 | MAV_4198 | - | 4e-17 | 26.86% (417) | transporter, monovalent cation:proton antiporter-2 (CPA2) |
| M. smegmatis MC2 155 | MSMEG_6769 | - | 9e-51 | 30.88% (408) | transporter, monovalent cation:proton antiporter-2 (CPA2) |
| M. thermoresistible (build 8) | TH_2104 | - | 6e-05 | 26.99% (289) | sulfate permease |
| M. ulcerans Agy99 | MUL_2572 | - | 7e-14 | 24.75% (408) | membrane transporter |
| M. vanbaalenii PYR-1 | Mvan_1424 | - | 9e-16 | 24.69% (405) | sodium/hydrogen exchanger |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2285|M.abscessus_ATCC_1997 MSNTAVTAAAALSKDVSLIFFADLVILLVAALACGAVAGKIGLPKMVGEI
MMAR_3635|M.marinum_M -----------MLADELLEFFLQFGLLLLAATILGRVAIRLGMPAIAGEL
Mb3264c|M.bovis_AF2122/97 -------------MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYL
Rv3236c|M.tuberculosis_H37Rv -------------MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYL
MUL_2572|M.ulcerans_Agy99 -------------MEVSRALLFEVGALLTTLALLGAIARRFALSPIPVYL
MLBr_00782|M.leprae_Br4923 -------------MEISGALLSQVGALLTTLAVLGAGARRYSLSPIPVYL
MAV_4198|M.avium_104 -------------MQISGTLLLQLGALLATLAVLGAAARRFALSPIPVYL
MSMEG_6769|M.smegmatis_MC2_155 -----------MPADTAIHFFLQLAVILMACRLAGLVARRIGQAQVVGEM
Mvan_1424|M.vanbaalenii_PYR-1 ---------------MDGHLFPTIAIILALATAAGVVATRLRQPLIVAFI
Mflv_0160|M.gilvum_PYR-GCK -----------MTLHQLYVALFLGGLVLLASIAATRLATGVGLPSLLLFL
TH_2104|M.thermoresistible__bu -----VIATAKENLIRLLPSRRDYAELPRSWRRDILAGITVGVVALPLAL
: . : :
MAB_2285|M.abscessus_ATCC_1997 AAGVLLGPTVFGRLFPETKDALFPSAGTGSEIISGLCLLAVVLLVGVAGM
MMAR_3635|M.marinum_M CAGVLLGPSILGQVAPGLSSWLLPEQVSERLGLDAVGTFGVLLLMGLTGM
Mb3264c|M.bovis_AF2122/97 LAGLSLG-----------NGGILGVAAAG-EFIATGAPIGVVLLLLALGL
Rv3236c|M.tuberculosis_H37Rv LAGLSLG-----------NGGILGVAAAG-EFIATGAPIGVVLLLLALGL
MUL_2572|M.ulcerans_Agy99 LAGLSLG-----------KGGVLPVAAAD-DFVATGAPIGIVLLLLTLGL
MLBr_00782|M.leprae_Br4923 MAGLSLG-----------KGGIMPVSAAD-EFITTGAPIGIVLLLLTLGL
MAV_4198|M.avium_104 LAGLALG-----------KGGLLPLATGG-QFITTSAPIGVVLLLLTLGC
MSMEG_6769|M.smegmatis_MC2_155 IAGVILGPSLLGRIAPDLQGLLFPPGITN-VVLYTTAQIGLVLYMFIIGL
Mvan_1424|M.vanbaalenii_PYR-1 MVGVAVG-------------PVGAGWVSADSTMELLARLGLAVLLFLVGL
Mflv_0160|M.gilvum_PYR-GCK GVGVLVG------------EGGLGLQFDNAQLGQDLGTAALAVILVEGGL
TH_2104|M.thermoresistible__bu AFGISSGVGAAAGLITAVVAGLVAAVFGGSHIQVSGPTGAMAVILAPIVA
*: * .: : :
MAB_2285|M.abscessus_ATCC_1997 HVDVDKLKQRLAGIATISVLGLAVPLAGG-------MAVGYLVPEPLRPA
MMAR_3635|M.marinum_M QVDLNLLKSNRLAITKISAACLLVPVVFG-------LGIGFLMPSVLT-G
Mb3264c|M.bovis_AF2122/97 EFSATEFASSLRHHLPSAGVDIVLNATPG-------AVAGWLLG------
Rv3236c|M.tuberculosis_H37Rv EFSATEFASSLRHHLPSAGVDIVLNATPG-------AVAGWLLG------
MUL_2572|M.ulcerans_Agy99 EFSATEFASSLRHHMPSAMVDIVLNATPG-------AVAGWLLG------
MLBr_00782|M.leprae_Br4923 EFSATEFASSLRRHLPSAGVDIILNATPG-------AVAGWLLG------
MAV_4198|M.avium_104 EFSVAEFSSSMRHHLPSAAVDVVLNAAPG-------AIAGWLLG------
MSMEG_6769|M.smegmatis_MC2_155 NFDVNHVKQRAGTAAAVSATGTLAPLALGG-----VAAIPLLAHGGFFGD
Mvan_1424|M.vanbaalenii_PYR-1 RLDLHMIRNTGPVAVITGLGQVLVTFALG-------LLIALALG------
Mflv_0160|M.gilvum_PYR-GCK TTRFSDIRKVLAPAAVLATLGVAVSTLVT------AAAVHWLLG------
TH_2104|M.thermoresistible__bu QHGLTSIALVTVLAGLIVLAAGITGLGRAVTFIPWPVIEGFTLG------
.
MAB_2285|M.abscessus_ATCC_1997 AVDRTVFALFLGTAVAVSAIPVIARILMDLGLASHEIAQVILAAAIVDDV
MMAR_3635|M.marinum_M GSNRLVFALFLAVALSVSAIAVIVKTLSDLGLMHRDIAQLILATAVIDNV
Mb3264c|M.bovis_AF2122/97 --LDGVAILGLAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDF
Rv3236c|M.tuberculosis_H37Rv --LDGVAILGLAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDF
MUL_2572|M.ulcerans_Agy99 --LDGVAILALAGVTYISSSGVVARLLEDLRRLGNRETPAVLSVLVLEDF
MLBr_00782|M.leprae_Br4923 --LDGVAVLALAGVTYISSSGVIARLLADLRRLGNRETPAVLSVLVLEDF
MAV_4198|M.avium_104 --LDGVAILCLAGVTYISSSGVVARLLEDLRRLGNRETPAVLSVLVLEDF
MSMEG_6769|M.smegmatis_MC2_155 GVNVGMAMMFLGASVAITAFPMLARIIFEKRLSGTSLGTLALACGATSDA
Mvan_1424|M.vanbaalenii_PYR-1 --MDNVTALYVAVALTFSSTIIIVKLLSDKRELEQLHGRIALGILIVQDI
Mflv_0160|M.gilvum_PYR-GCK --MNWQLALLLGAVISSTDAAAVFSVLR-VVPLPRRLSGLLEAESGFNDA
TH_2104|M.thermoresistible__bu -IAAIIFLQQVPAAFATEAPAGQRTLVAAWHVVTHADWTAAVKTLSVVSL
: : .
MAB_2285|M.abscessus_ATCC_1997 AGWLLLSAVTGMASDSGTGGVAVLKMAVAAIVAVVALTALTRPALRNRLA
MMAR_3635|M.marinum_M IAWVLLSVVCAMALAHLS--LGTVLLTVFLIISVVAATIIGRKIVEVFVN
Mb3264c|M.bovis_AF2122/97 AMAAYLPLFAVLAT------DGSWLEAVVGMTVAIAALLGAFAASYRWGH
Rv3236c|M.tuberculosis_H37Rv AMAAYLPLFAVLAT------DGSWLEAVVGMTVAIAALLGAFAASYRWGH
MUL_2572|M.ulcerans_Agy99 AMAGYLPLFTVLAL------HGDWLHALGGTLAAIAALLGAFAASFYWGH
MLBr_00782|M.leprae_Br4923 AMAAYLPLFAVLAA------GGSWLDAVVGMIVAVCALFAAFAASYHWGH
MAV_4198|M.avium_104 AMAAYLPLFAVLAS------GGGWLHAVVGMVVAVSALVAAFAASYRWGH
MSMEG_6769|M.smegmatis_MC2_155 ISWCILAVVLAVYR-------NSPVMAVVAIVGGLVYTLVLLTLGRRAFA
Mvan_1424|M.vanbaalenii_PYR-1 VVVVVMIALTASGRGG----EGSVGAGIAAVALKGIGLLATLWVLMRFVL
Mflv_0160|M.gilvum_PYR-GCK PAVILVMLFSVVPMELN-------AVDIVGTLVYELGIGTVLGLGFGVLG
TH_2104|M.thermoresistible__bu VALLMVVLPRLHRSIPESLTAVVAATVIVTVFGISVATIGELPSQLPTPV
: :
MAB_2285|M.abscessus_ATCC_1997 RRCSRWSAPTST------TVTVATIIVCATAGQLLGFEPVIGAFFAGILV
MMAR_3635|M.marinum_M SRQQPAAAEHSAGPRPILAYAVGLVMLAAAATHALKLEPVLGAFAAGIML
Mb3264c|M.bovis_AF2122/97 HVGRLVTHPDSE---QLLLRVLGITLIVAAVAESLHASAAVGAFLVGLTL
Rv3236c|M.tuberculosis_H37Rv HVGRLVTHPDSE---QLLLRVLGITLIVAAVAESLHASAAVGAFLVGLTL
MUL_2572|M.ulcerans_Agy99 HFGRLFAHPDSE---QLLLRVLGITLMVAALAETLHASAAVGAFLVGLTL
MLBr_00782|M.leprae_Br4923 HVGRLVAHPDSE---QLLLRVLGVTLIVAAVAESLHASAAVGAFLVGLTL
MAV_4198|M.avium_104 HVQRLVEHPDSE---QLMLRVLGITLIVAAMAESLHASAAVGAFLVGLTL
MSMEG_6769|M.smegmatis_MC2_155 KLGDAAEARQAIT-APMLSTVLIVLMACAWLTDTIGIYAIFGAFILGAAM
Mvan_1424|M.vanbaalenii_PYR-1 PWLMPQIARSQE---LLVLFGVAYAVSVASFSEWLGFSSEVGAFLAGVSL
Mflv_0160|M.gilvum_PYR-GCK AMTLRRIALPAAG--LYPLATFGLGMLAFAAAGTAHGSGFLAAYLASVVL
TH_2104|M.thermoresistible__bu LPQADMGAMQTLLGAALAIAALAAIESLLSARVAATMSATGPYHPDRELV
. . :
MAB_2285|M.abscessus_ATCC_1997 IAATPAGSRVHKPLHAMAVAFFGPIFFATIGLQLDLGRLLSGPVLALTAS
MMAR_3635|M.marinum_M AALPPDRRSGLDSLHPVVNNVLAPLYFATAGLQADLTGLADRTTLAAALV
Mb3264c|M.bovis_AF2122/97 TGETADRAR---MVLTPLRDLFATIFFLGIGLSVDPGKLVS--MLPVALA
Rv3236c|M.tuberculosis_H37Rv TGETADRAR---MVLTPLRDLFATIFFLGIGLSVDPGKLVS--MLPVALA
MUL_2572|M.ulcerans_Agy99 TGETAERAR---RVLGPLRDLFAAIFFLGIGLSVAPKELIP--ALPVAIL
MLBr_00782|M.leprae_Br4923 TGDTAERAR---KVLGPLRDLFAAIFFLAIGISVDPHKLLP--MFPTALI
MAV_4198|M.avium_104 TGETATRTR---QVLAPLRDLFAAIFFLAIGYSVDPHELIP--MLPAALI
MSMEG_6769|M.smegmatis_MC2_155 PSGFFAERLTG-RLEPLTTTFLLPLFFVYSGLNTEIGLVNTPFLWAVTAG
Mvan_1424|M.vanbaalenii_PYR-1 AGTQFRDALG--ARLVSLRDFLLFFFFLNLGAGLDFSEAAG--QITAAII
Mflv_0160|M.gilvum_PYR-GCK ANSGLPHRSATRSFAEGAGWLAQIGVFVILGLLVSPDQLLD-EVVPAIVA
TH_2104|M.thermoresistible__bu GQGMASVASGLFGGMPATGAIARTAVNVRSGARTRLAAIVHSLVLLAVVY
. *
MAB_2285|M.abscessus_ATCC_1997 ICVVAVFSKFLGAGMGARISGFSWPESVAVGAGLNTRGVIQIVIAMVGVR
MMAR_3635|M.marinum_M VLAAAVASKFLGAYIGAKSSGRSGAEAVALGAGLNARGVIQIIIADTAYD
Mb3264c|M.bovis_AF2122/97 LAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAG-
Rv3236c|M.tuberculosis_H37Rv LAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAG-
MUL_2572|M.ulcerans_Agy99 LAVVTAATKVLTGMFAARRDGVARRGQLRAGTALIARGEFSLIIIGLVG-
MLBr_00782|M.leprae_Br4923 LATVTAVTKVATGILAARYDGVARRGQLRAGTALVARGEFSLIIIGLVG-
MAV_4198|M.avium_104 LAAATAATKVATGIFAARHDGVARRGQLRAGTALIARGEFSLIIIGLAG-
MSMEG_6769|M.smegmatis_MC2_155 LLVVAVVGKGVACAVAARLSRVPVRDSLALGSLMNARGLIELILLNIGLE
Mvan_1424|M.vanbaalenii_PYR-1 LSVFVLVAKPAIVIAIMSVMRYPVRVGFLVGLPLAQISEFSLILAALGLS
Mflv_0160|M.gilvum_PYR-GCK GLALLLLARPISVFLSLIGFRVPWREKMFLSWAGLRGAVPIVLCTYPIVA
TH_2104|M.thermoresistible__bu LATGPVSAIPLSALAGVLMVTSFRMVSLHTARRILRSTRSDALTFVLTAL
. . . :
MAB_2285|M.abscessus_ATCC_1997 CGVFSPEVFTALVVTTIATTAIAGPVLKRTLTPRRQLP-AVISKPPQEPA
MMAR_3635|M.marinum_M LGIFNDSFYTIVLLTAIATSVMAAPILRIAAARIAIDPDDEIRRQDALPE
Mb3264c|M.bovis_AF2122/97 ---ASIPGVAALATAYVFVMAIVGPILARYTGGGLPAAAVASN-------
Rv3236c|M.tuberculosis_H37Rv ---ASIPGVAALATAYVFVMAIVGPILARYTGGGLPAAAVASN-------
MUL_2572|M.ulcerans_Agy99 ---ASIPAVAALATAYVFIMAVAGPVLARYTGG--PVATTA---------
MLBr_00782|M.leprae_Br4923 ---TSTPAVAALATAYVFIMAIAGPVLARYTPGSLPTSSGSAN-------
MAV_4198|M.avium_104 ---SSLPAVAALATSYVFIMAIAGPVLARYTGPR-PAAPAT---------
MSMEG_6769|M.smegmatis_MC2_155 AGVITPTLFTILVLVAIVTTLMASPIFEFVYGRHRTDETGDTTQERVPQP
Mvan_1424|M.vanbaalenii_PYR-1 LGHISNATVSLITVVGLITIAASTYMTMYSDGIFARSQRWLSHLERKHQR
Mflv_0160|M.gilvum_PYR-GCK GVPDSWRLLHIVFILVVLYTAIQGPSLRRVAEWLNLIPRDTTREIQVDAA
TH_2104|M.thermoresistible__bu VT-ITFDLIEAVQIGVLVAAFFALRNVARRSGVTREELPGEPQPGDERIA
. : :
MAB_2285|M.abscessus_ATCC_1997 LNR-----------------------------------------------
MMAR_3635|M.marinum_M AH------------------------------------------------
Mb3264c|M.bovis_AF2122/97 --------------------------------------------------
Rv3236c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2572|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00782|M.leprae_Br4923 --------------------------------------------------
MAV_4198|M.avium_104 --------------------------------------------------
MSMEG_6769|M.smegmatis_MC2_155 SA------------------------------------------------
Mvan_1424|M.vanbaalenii_PYR-1 DHEVAGLSDGDFDIILFGLGRFGSHLADRLSGAGHRVLGVDFDPHGVRAH
Mflv_0160|M.gilvum_PYR-GCK PLDVLGAELLTMTVLPGSRLHNVTVLELRLPDPSVITLIIRDG----QSF
TH_2104|M.thermoresistible__bu LLRLEGSMFFGVAERMSSTISEIEADDISVVIIRLSQLG-TLDATGANSL
MAB_2285|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3635|M.marinum_M --------------------------------------------------
Mb3264c|M.bovis_AF2122/97 --------------------------------------------------
Rv3236c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2572|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00782|M.leprae_Br4923 --------------------------------------------------
MAV_4198|M.avium_104 --------------------------------------------------
MSMEG_6769|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1424|M.vanbaalenii_PYR-1 RRDGVTTTFGSAEDLDLLEALPLDRAKYVISAIPVLQTNLALLHGLRQHQ
Mflv_0160|M.gilvum_PYR-GCK VPQPVTRLQIGDELLIVTTSVTRDQAERRLRAVSRRGKLAYWFDEYGDPA
TH_2104|M.thermoresistible__bu AQIATELERRGITVIIKGVQPEHSKLLSNVGVFESLRHEKHLIDSLEDAI
MAB_2285|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3635|M.marinum_M --------------------------------------------------
Mb3264c|M.bovis_AF2122/97 --------------------------------------------------
Rv3236c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2572|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00782|M.leprae_Br4923 --------------------------------------------------
MAV_4198|M.avium_104 --------------------------------------------------
MSMEG_6769|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1424|M.vanbaalenii_PYR-1 FSGAVALTAHTRHDAERLRATGVEIVIEPFSSAAHTTSNTLHDLLTTEFE
Mflv_0160|M.gilvum_PYR-GCK --------------------------------------------------
TH_2104|M.thermoresistible__bu EHARSHVARQQTARTTS---------------------------------
MAB_2285|M.abscessus_ATCC_1997 --------------------
MMAR_3635|M.marinum_M --------------------
Mb3264c|M.bovis_AF2122/97 --------------------
Rv3236c|M.tuberculosis_H37Rv --------------------
MUL_2572|M.ulcerans_Agy99 --------------------
MLBr_00782|M.leprae_Br4923 --------------------
MAV_4198|M.avium_104 --------------------
MSMEG_6769|M.smegmatis_MC2_155 --------------------
Mvan_1424|M.vanbaalenii_PYR-1 DTDDEGYSDDEGGAQPRPSR
Mflv_0160|M.gilvum_PYR-GCK --------------------
TH_2104|M.thermoresistible__bu --------------------