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MSGFGFPTLAIVVIVGMIGPLLALNTRLRIPVVIGELLAGIVIGRTGFGWIDAFDPTFKMFADVGFALVM FVAGTHVPVRDKTMRASLPQAALRAIVVGAVAAVLGVLLANVFHTGHAPLYAVLIASSSAALVLPVIDSL GLGGPKVLITTAQVAIADTASIILLPLVIDLKHAPRAAVGAVAVAACAGIVFVILHALDQAGKLDRFHDY SKQRRVAMELRISLAIVFGLAALAVETHVSIMLAGFALGLVVAGIGEPRRLAKQLFGFTEGFFSPLFFVW LGASLHVRELGENPKLILLGVGLGVAAVLAHLVVRIFGQPLPLGALAAAQLGVPIAAAAIGEQQQSLIHG EASALILGALVTIAAATVGGSLYAKTSQGNQPGVAKPERPVDDSEGSGAGGGAEGAGGGVAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0385 | - | - | 100% (412) | hypothetical protein MAB_0385 |
| M. abscessus ATCC 19977 | MAB_2285 | - | 1e-12 | 24.45% (409) | Na+/H+ antiporter |
| M. abscessus ATCC 19977 | MAB_4717c | - | 7e-09 | 23.60% (322) | potassium/proton antiporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3264c | - | 1e-11 | 26.99% (389) | integral membrane transport protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3236c | - | 1e-11 | 26.99% (389) | integral membrane transport protein |
| M. leprae Br4923 | MLBr_00782 | - | 5e-11 | 24.16% (356) | putative transmembrane transport protein |
| M. marinum M | MMAR_2583 | - | 1e-10 | 26.93% (323) | sodium/hydrogen exchanger (antiporter) |
| M. avium 104 | MAV_4118 | - | 1e-135 | 65.01% (383) | transporter, monovalent cation:proton antiporter-2 (CPA2) |
| M. smegmatis MC2 155 | MSMEG_6769 | - | 2e-11 | 23.99% (396) | transporter, monovalent cation:proton antiporter-2 (CPA2) |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2572 | - | 7e-11 | 27.60% (308) | membrane transporter |
| M. vanbaalenii PYR-1 | Mvan_1424 | - | 3e-16 | 25.65% (386) | sodium/hydrogen exchanger |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0385|M.abscessus_ATCC_1997 -----MSGFGFPTLAIVVIVGMIGPLLALNTRLRIPVVIGELLAGIVIGR
MAV_4118|M.avium_104 MQNERVQGFGFHTLALLTAVGFAGPLLASAKRFRIPVVIGELIAGLAIGR
Mb3264c|M.bovis_AF2122/97 --MEVSRALLFELGVLLAVLAVLG---AVARRFALSPIPVYLLAGLSLGN
Rv3236c|M.tuberculosis_H37Rv --MEVSRALLFELGVLLAVLAVLG---AVARRFALSPIPVYLLAGLSLGN
MLBr_00782|M.leprae_Br4923 --MEISGALLSQVGALLTTLAVLG---AGARRYSLSPIPVYLMAGLSLGK
MUL_2572|M.ulcerans_Agy99 --MEVSRALLFEVGALLTTLALLG---AIARRFALSPIPVYLLAGLSLGK
Mvan_1424|M.vanbaalenii_PYR-1 -----MDGHLFPTIAIILALATAAG--VVATRLRQPLIVAFIMVGVAVGP
MSMEG_6769|M.smegmatis_MC2_155 MPADTAIHFFLQLAVILMACRLAG---LVARRIGQAQVVGEMIAGVILGP
MMAR_2583|M.marinum_M -MSLQQLYLAMLIGGFVLLASIVG--TRLATRVGFPSMLLFLLVGVIVGE
:: . * . : ::.*: :*
MAB_0385|M.abscessus_ATCC_1997 TGFGWIDA-----------FDPTFKMFADVGFALVMFVAGTHVPVR--DK
MAV_4118|M.avium_104 TGFGVVDV-----------ADPTFQLLANIGFALVMFVVGTHVPLR--AR
Mb3264c|M.bovis_AF2122/97 GGILGVAA-----------AGEFIATGAPIGVVLLLLALGLEFSATEFAS
Rv3236c|M.tuberculosis_H37Rv GGILGVAA-----------AGEFIATGAPIGVVLLLLALGLEFSATEFAS
MLBr_00782|M.leprae_Br4923 GGIMPVSA-----------ADEFITTGAPIGIVLLLLTLGLEFSATEFAS
MUL_2572|M.ulcerans_Agy99 GGVLPVAA-----------ADDFVATGAPIGIVLLLLTLGLEFSATEFAS
Mvan_1424|M.vanbaalenii_PYR-1 VGAGWVS------------ADSTMELLARLGLAVLLFLVGLRLDLHMIRN
MSMEG_6769|M.smegmatis_MC2_155 SLLGRIAPDLQGLLFPPGITNVVLYTTAQIGLVLYMFIIGLNFDVNHVKQ
MMAR_2583|M.marinum_M DGFGLRFD-----------DVELARNMGTAALAVILVEGGLTTRFSDIRK
. ...: :. *
MAB_0385|M.abscessus_ATCC_1997 TMRASLPQAALRAIVVGAVAAVLGVLLAN---------VFHTGHAPLYAV
MAV_4118|M.avium_104 LMRSALPAALARAALAGGIAAVLGVALAV---------QFDTGHAALYAV
Mb3264c|M.bovis_AF2122/97 SLRHHLPSAGVDIVLNATPGAVAGWLLG----------LDGVAILGLAGV
Rv3236c|M.tuberculosis_H37Rv SLRHHLPSAGVDIVLNATPGAVAGWLLG----------LDGVAILGLAGV
MLBr_00782|M.leprae_Br4923 SLRRHLPSAGVDIILNATPGAVAGWLLG----------LDGVAVLALAGV
MUL_2572|M.ulcerans_Agy99 SLRHHMPSAMVDIVLNATPGAVAGWLLG----------LDGVAILALAGV
Mvan_1424|M.vanbaalenii_PYR-1 TGPVAVITGLGQVLVTFALGLLIALALG----------MDNVTALYVAVA
MSMEG_6769|M.smegmatis_MC2_155 RAGTAAAVSATGTLAPLALGGVAAIPLLAHGGFFGDGVNVGMAMMFLGAS
MMAR_2583|M.marinum_M VLAPAATLATVGVMVSMVVTAVGVHLVLG----------VSWQAALLLGA
. : : :
MAB_0385|M.abscessus_ATCC_1997 LIASSSAALVLPVIDSLGLGGPKVLITTAQVAIADTASIILLPLVIDLKH
MAV_4118|M.avium_104 LMASSSAALALPVIDSLRLRGPRVLSVTTQIAIADAACIVLLPLVIDIRR
Mb3264c|M.bovis_AF2122/97 TYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLAT
Rv3236c|M.tuberculosis_H37Rv TYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLAT
MLBr_00782|M.leprae_Br4923 TYISSSGVIARLLADLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLAA
MUL_2572|M.ulcerans_Agy99 TYISSSGVVARLLEDLRRLGNRETPAVLSVLVLEDFAMAGYLPLFTVLAL
Mvan_1424|M.vanbaalenii_PYR-1 LTFSSTIIIVKLLSDKRELEQLHGRIALGILIVQDIVVVVVMIALTASGR
MSMEG_6769|M.smegmatis_MC2_155 VAITAFPMLARIIFEKRLSGTSLGTLALACGATSDAISWCILAVVLAVYR
MMAR_2583|M.marinum_M IVSSTDAAAVFSVLRVLPLPRRVAGLLEAESGFNDAPAVILVLMFSEVPF
:: . : * : .
MAB_0385|M.abscessus_ATCC_1997 APRAAVGAVAVAACAGIVFVILHALDQAGKLD-RFHDYSKQRRVAMELRI
MAV_4118|M.avium_104 APTAALGALAVAGCAAALFVLLRAADRKGWRR-RLHAYSEQHRFALELRT
Mb3264c|M.bovis_AF2122/97 DGSWLEAVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRV--
Rv3236c|M.tuberculosis_H37Rv DGSWLEAVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRV--
MLBr_00782|M.leprae_Br4923 GGSWLDAVVGMIVAVCALFAAFAASYHWGHHVGRLVAHPDSEQLLLRV--
MUL_2572|M.ulcerans_Agy99 HGDWLHALGGTLAAIAALLGAFAASFYWGHHFGRLFAHPDSEQLLLRV--
Mvan_1424|M.vanbaalenii_PYR-1 GGEGSVGAGIAAVALKGIGLLATLWVLMRFVLPWLMPQIARSQELLVLFG
MSMEG_6769|M.smegmatis_MC2_155 NSPVMAVVAIVGGLVYTLVLLTLGRRAFAKLGDAAEARQAITAPMLST--
MMAR_2583|M.marinum_M AFRPAAALEALVFELLVGAAIGLAIGYLGAFTLRRIALPASGLYPIAT--
:
MAB_0385|M.abscessus_ATCC_1997 SLAIVFGLAALAVETHVSIMLAGFALGLVVAGIGEPRRLAKQLFGFTEGF
MAV_4118|M.avium_104 SLLVLFALAALAVATQVSIMLAGFAVGLVVGAVGEPHRLARQLFGITEGF
Mb3264c|M.bovis_AF2122/97 -LGITLIVAAVAESLHASAAVGAFLVGLTLT--GETADRARMVLTPLRDL
Rv3236c|M.tuberculosis_H37Rv -LGITLIVAAVAESLHASAAVGAFLVGLTLT--GETADRARMVLTPLRDL
MLBr_00782|M.leprae_Br4923 -LGVTLIVAAVAESLHASAAVGAFLVGLTLT--GDTAERARKVLGPLRDL
MUL_2572|M.ulcerans_Agy99 -LGITLMVAALAETLHASAAVGAFLVGLTLT--GETAERARRVLGPLRDL
Mvan_1424|M.vanbaalenii_PYR-1 -VAYAVSVASFSEWLGFSSEVGAFLAGVSLAG-TQFRDALGARLVSLRDF
MSMEG_6769|M.smegmatis_MC2_155 VLIVLMACAWLTDTIGIYAIFGAFILGAAMPSGFFAERLTGRLEPLTTTF
MMAR_2583|M.marinum_M -FGLGLVAFAAAGESHASGFIAAYLAAVVLANTGLPHRAATRSFAEGVGW
. . : ...: . :
MAB_0385|M.abscessus_ATCC_1997 FSPL-FFVWLGASLHV--RELG-ENPKLILLGVGLGVAAVLAHLVVRIFG
MAV_4118|M.avium_104 FSPL-FFVWLGASLQV--RELG-AHPQLILLGAGLGCGAVLAHCAGRLLG
Mb3264c|M.bovis_AF2122/97 FATI-FFLGIGLSVDP--GKLVSMLPVALALAAVTAATKVATGMFAARRE
Rv3236c|M.tuberculosis_H37Rv FATI-FFLGIGLSVDP--GKLVSMLPVALALAAVTAATKVATGMFAARRE
MLBr_00782|M.leprae_Br4923 FAAI-FFLAIGISVDP--HKLLPMFPTALILATVTAVTKVATGILAARYD
MUL_2572|M.ulcerans_Agy99 FAAI-FFLGIGLSVAP--KELIPALPVAILLAVVTAATKVLTGMFAARRD
Mvan_1424|M.vanbaalenii_PYR-1 LLFF-FFLNLGAGLDF--SEAAGQITAAIILSVFVLVAKPAIVIAIMSVM
MSMEG_6769|M.smegmatis_MC2_155 LLPL-FFVYSGLNTEIGLVNTPFLWAVTAGLLVVAVVGKGVACAVAARLS
MMAR_2583|M.marinum_M LAQIGLFVLLGLLVEP-IEVIHDLIAAIVVGLLLLLVARPLSVVLSLSGF
: : :*: * .
MAB_0385|M.abscessus_ATCC_1997 QPLPLGALAAAQLGVPIAAAAIGEQQQSLIHGEASALILGALVTIAAATV
MAV_4118|M.avium_104 QPLTLAVLSAAQLGVPVAAATIGTQQHLLAPGEASALMFGALLTIAAASI
Mb3264c|M.bovis_AF2122/97 GVARRGQLRAG--TALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAI
Rv3236c|M.tuberculosis_H37Rv GVARRGQLRAG--TALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAI
MLBr_00782|M.leprae_Br4923 GVARRGQLRAG--TALVARGEFSLIIIGLVGTSTPAVAALATAYVFIMAI
MUL_2572|M.ulcerans_Agy99 GVARRGQLRAG--TALIARGEFSLIIIGLVGASIPAVAALATAYVFIMAV
Mvan_1424|M.vanbaalenii_PYR-1 RYPVRVGFLVGLPLAQISEFSLILAALGLSLGHISNATVSLITVVGLITI
MSMEG_6769|M.smegmatis_MC2_155 RVPVRDSLALGSLMNARGLIELILLNIGLEAGVITPTLFTILVLVAIVTT
MMAR_2583|M.marinum_M RIPWRDQVFLS-WAGLRGAVPIVLATFPIVAGVPDSYRLLNIVFMLVVVF
. . . : : :
MAB_0385|M.abscessus_ATCC_1997 GG---------SLYAKTSQGNQPGVAKPERPVDDSEGSGAGGGAEGAGGG
MAV_4118|M.avium_104 AA---------GLAARRQGAPEPG--EPAR--------------------
Mb3264c|M.bovis_AF2122/97 VG---------PILARYTGGGLPAAAVASN--------------------
Rv3236c|M.tuberculosis_H37Rv VG---------PILARYTGGGLPAAAVASN--------------------
MLBr_00782|M.leprae_Br4923 AG---------PVLARYTPGSLPTSSGSAN--------------------
MUL_2572|M.ulcerans_Agy99 AG---------PVLARYTGG--PVATTA----------------------
Mvan_1424|M.vanbaalenii_PYR-1 AASTYMTMYSDGIFARSQRWLSHLERKHQRDHEVAGLSDGDFDIILFGLG
MSMEG_6769|M.smegmatis_MC2_155 LMAS-------PIFEFVYGRHRTDETGDTTQERVPQPSA-----------
MMAR_2583|M.marinum_M TLVQ------GPSLRPIAHLLGLISREATREIQVEAAPLDVLDAELVTMT
MAB_0385|M.abscessus_ATCC_1997 VAG-----------------------------------------------
MAV_4118|M.avium_104 --------------------------------------------------
Mb3264c|M.bovis_AF2122/97 --------------------------------------------------
Rv3236c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00782|M.leprae_Br4923 --------------------------------------------------
MUL_2572|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1424|M.vanbaalenii_PYR-1 RFGSHLADRLSGAGHRVLGVDFDPHGVRAHRRDGVTTTFGSAEDLDLLEA
MSMEG_6769|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2583|M.marinum_M VQPPSRLHNVTVLELRLPDPAVITLIIRKGHTFVPMPDTRIQRGDELLIV
MAB_0385|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4118|M.avium_104 --------------------------------------------------
Mb3264c|M.bovis_AF2122/97 --------------------------------------------------
Rv3236c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00782|M.leprae_Br4923 --------------------------------------------------
MUL_2572|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1424|M.vanbaalenii_PYR-1 LPLDRAKYVISAIPVLQTNLALLHGLRQHQFSGAVALTAHTRHDAERLRA
MSMEG_6769|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2583|M.marinum_M TTSTTRAAAESRLRAVSRRGKLAYWFDEYGEPD-----------------
MAB_0385|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4118|M.avium_104 --------------------------------------------------
Mb3264c|M.bovis_AF2122/97 --------------------------------------------------
Rv3236c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00782|M.leprae_Br4923 --------------------------------------------------
MUL_2572|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1424|M.vanbaalenii_PYR-1 TGVEIVIEPFSSAAHTTSNTLHDLLTTEFEDTDDEGYSDDEGGAQPRPSR
MSMEG_6769|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2583|M.marinum_M --------------------------------------------------