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MTVSQFTSTARESAAATYSRRLPIRPVEARGARVRAEDGRWYVDCLAAAGAMSLGWNHPAVNEAVMKTVS SGEPLLSLDFHTPSRDRFVEELLSILPVRLATDASIHLCSPSGASAVEAALMLAEIATGGREHIGVQGGF HGCTRAARAASSGGGLRRQPVVLSPQASFLPYPQEYRSPFGVSGERGVELAIAAAEAVARPHSGVTAPAS LIAEFVLGEGGVIPAPARWGQALRRTASTLGVPLIADEVQAGMYRTGPAWAFQHSGIEPDMMVISKGLGS GIPIAVLVVRKEFDVWEPGAFTGTFRGNAMAFAAASAVIRFARENGLRGQVTARGKIFLDGLNAVASDSA LVGDVRGVGLMLGVEIVDPDMPWPDDAGAPAPELAARIQQACLQHGLIVETGGQYGNVVRFLPPLTIDEP DIAAALNAFDAALSAVERTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1684 | - | - | 100% (440) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. abscessus ATCC 19977 | MAB_4417c | - | 5e-54 | 34.88% (410) | aminotransferase |
| M. abscessus ATCC 19977 | MAB_2266c | - | 5e-51 | 31.79% (431) | diaminobutyrate--2-oxoglutarate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1683 | argD | 8e-40 | 33.73% (415) | acetylornithine aminotransferase |
| M. gilvum PYR-GCK | Mflv_4833 | - | 2e-48 | 31.22% (426) | diaminobutyrate--2-oxoglutarate aminotransferase |
| M. tuberculosis H37Rv | Rv1655 | argD | 8e-40 | 33.73% (415) | acetylornithine aminotransferase |
| M. leprae Br4923 | MLBr_00485 | gabT | 2e-36 | 28.84% (423) | 4-aminobutyrate aminotransferase |
| M. marinum M | MMAR_0166 | gabT_2 | 0.0 | 72.33% (430) | 4-aminobutyrate aminotransferase, GabT_2 |
| M. avium 104 | MAV_3115 | argD | 6e-37 | 32.48% (428) | acetylornithine aminotransferase |
| M. smegmatis MC2 155 | MSMEG_2487 | - | 4e-50 | 34.43% (427) | 4-aminobutyrate aminotransferase |
| M. thermoresistible (build 8) | TH_3246 | - | 9e-54 | 32.48% (431) | PUTATIVE diaminobutyrate--2-oxoglutarate aminotransferase |
| M. ulcerans Agy99 | MUL_4930 | gabT_2 | 0.0 | 72.09% (430) | 4-aminobutyrate aminotransferase, GabT_2 |
| M. vanbaalenii PYR-1 | Mvan_5273 | - | 9e-50 | 32.86% (426) | diaminobutyrate--2-oxoglutarate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1683|M.bovis_AF2122/97 -----------MTGASTTTATMRQRWQAVMMNNYG-TPPIALASGDGAVV
Rv1655|M.tuberculosis_H37Rv -----------MTGASTTTATMRQRWQAVMMNNYG-TPPIALASGDGAVV
MAV_3115|M.avium_104 --------------MVTNTDALRRRWEAVMMHNYG-TPPVALASGEGAVV
MLBr_00485|M.leprae_Br4923 MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVTRAAGGVI
MSMEG_2487|M.smegmatis_MC2_155 ----------------------MTELSQALKQATG----VIAARGEGVLL
MMAR_0166|M.marinum_M -----------------MLAKNPPPMRESNAATYSRRLPIRLVEARGTRV
MUL_4930|M.ulcerans_Agy99 -----------------MLAKNPPPMRESNAATYSRRLPIRLVEARGTRV
MAB_1684|M.abscessus_ATCC_1997 ----------------MTVSQFTSTARESAAATYSRRLPIRPVEARGARV
Mflv_4833|M.gilvum_PYR-GCK -MTATVVTPPTTDPVRENALPDVYDRVESEVRSYCRNWPATMASARGSWM
Mvan_5273|M.vanbaalenii_PYR-1 -----MSTPATIVRPGEPDLPAVYSSVESEVRSYCRNWPATMAHAQGSWV
TH_3246|M.thermoresistible__bu -----MSLLATTS---ETELPEVFSTIESEVRSYCRGWPAVMESARGSWI
. * :
Mb1683|M.bovis_AF2122/97 TDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYATEPG
Rv1655|M.tuberculosis_H37Rv TDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYATEPG
MAV_3115|M.avium_104 TDVDGNTYLDLLGGIAVNVLGHRHPAIIEAVTKQLSTLGHTSNLYATEPS
MLBr_00485|M.leprae_Br4923 EDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIITPYEE
MSMEG_2487|M.smegmatis_MC2_155 YDEQDRRYLDFTAGIGVTSTGHCHPRVVEAAQRQVGTLIHGQYTTVMHRP
MMAR_0166|M.marinum_M RDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIRTVDSGEPWLSLDFHTPA
MUL_4930|M.ulcerans_Agy99 RDSSGRWYIDCLAAAGAMSLGWNHPVVSEAVIETVDSGEPWLSLDFHTPA
MAB_1684|M.abscessus_ATCC_1997 RAEDGRWYVDCLAAAGAMSLGWNHPAVNEAVMKTVSSGEPLLSLDFHTPS
Mflv_4833|M.gilvum_PYR-GCK TDTSGRQYLDFFAGAGALNYGHNNPVLKAPLIDYLSQDSIVHSLDMATAA
Mvan_5273|M.vanbaalenii_PYR-1 TDVSGRRYLDFFAGAGALNYGHNNPILKQPLLDYLSSDMIVHSLDMATEA
TH_3246|M.thermoresistible__bu TDVSGQRYLDFFAGAGALNYGHNNPKLKEPLLKYLMSDNIVHSLDMATAA
... :* .. .. * * : . :
Mb1683|M.bovis_AF2122/97 IALAEELVALLGADQR--------------TRVFFCNSGAEANEAAFKLS
Rv1655|M.tuberculosis_H37Rv IALAEELVALLGADQR--------------TRVFFCNSGAEANEAAFKLS
MAV_3115|M.avium_104 LALAEELVALLGAGHEPAGHESGGTESAGTARVFFCNSGTEANEVAFKLS
MLBr_00485|M.leprae_Br4923 YVAVTEQLNRITPGSG-------------EKRSVLFNSGAEAVENSIKVA
MSMEG_2487|M.smegmatis_MC2_155 LLTLVERLGEVLPAGL--------------DRMFFANSGSEAIEAALRLS
MMAR_0166|M.marinum_M REQFVEDLLSILPPGL----------AADGRVHLCSPSGASAVEAALTLA
MUL_4930|M.ulcerans_Agy99 REQFVEDLLSILPPGL----------AADGRVHLCSPSGASAVEAALTLA
MAB_1684|M.abscessus_ATCC_1997 RDRFVEELLSILPVRL----------ATDASIHLCSPSGASAVEAALMLA
Mflv_4833|M.gilvum_PYR-GCK KTEFLETFERLILRPR----------SLDYKVQFPGPTGANAVESALKLA
Mvan_5273|M.vanbaalenii_PYR-1 KTRFLETFERLILRPR----------GLDYKVQFPGPTGANTVEAALKLA
TH_3246|M.thermoresistible__bu KQEFLETFSELILKPR----------GLDYKVQFPGPTGANAVESALKLA
* . : . :*:.: * :: ::
Mb1683|M.bovis_AF2122/97 R-LTGRTKLVAAHDAFHGRTMGSLALTGQPA-KQTPFAPLPGDVTHVGYG
Rv1655|M.tuberculosis_H37Rv R-LTGRTKLVAAHDAFHGRTMGSLALTGQPA-KQTPFAPLPGDVTHVGYG
MAV_3115|M.avium_104 R-LTGRTKLVAAQEAFHGRTMGSLALTGQPS-KQAPFAPLPGDVTHVPYG
MLBr_00485|M.leprae_Br4923 RSYTRKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLS
MSMEG_2487|M.smegmatis_MC2_155 RQATGRPNVIVFHGGFHGRTVAAASMTTSGTKFRSGFSPLMAGVHVSPFP
MMAR_0166|M.marinum_M EIATGGREHVGVQGGFHGCTRAARAASSGGG-LRQQPVVMAPRTTFLPFP
MUL_4930|M.ulcerans_Agy99 EIATGGREHVGVQGGFHGCTRAARAASSGGG-LRQQPVVMAPRTTFLPFP
MAB_1684|M.abscessus_ATCC_1997 EIATGGREHIGVQGGFHGCTRAARAASSGGG-LRRQPVVLSPQASFLPYP
Mflv_4833|M.gilvum_PYR-GCK RKVTGRESIINFTNAFHGMTLGALSVTGNSM-KRAGAGIPLVHATPMPYD
Mvan_5273|M.vanbaalenii_PYR-1 RKVTGRESIISFTNAFHGMTLGALSVTGNSM-KRAGAGIPLVHATPMPYD
TH_3246|M.thermoresistible__bu RKVTGRESIVSFTNAFHGMTLGALSVTGNSM-KRAGAGVPLVHSTPMPYD
. * : .:** * : : : :
Mb1683|M.bovis_AF2122/97 ----------------------DVDALAAAV-DDHTAAVFLEPIMGESGV
Rv1655|M.tuberculosis_H37Rv ----------------------DVDALAAAV-DDHTAAVFLEPIMGESGV
MAV_3115|M.avium_104 ----------------------DTEALAAAV-DDGTAAVFLEPIMGESGV
MLBr_00485|M.leprae_Br4923 YPYRDGLLNKDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGF
MSMEG_2487|M.smegmatis_MC2_155 DPTHFG---WPVEQTTDFALSQLDYVLQTVSAPADTAAFFVEPVLGEGGY
MMAR_0166|M.marinum_M QNYRCPF-GVGGERGVDLAVTAVEQLAAPHAGISAPASIISEFVLGEGGV
MUL_4930|M.ulcerans_Agy99 QNYRCPF-GVGGERGVDLAVTAVEQLAAPHAGISAPASIISEFVLGEGGV
MAB_1684|M.abscessus_ATCC_1997 QEYRSPF-GVSGERGVELAIAAAEAVARPHSGVTAPASLIAEFVLGEGGV
Mflv_4833|M.gilvum_PYR-GCK NYFGG---------ITEDFHWFERVLDDSGGGLNHPAAVIVETVQGEGGL
Mvan_5273|M.vanbaalenii_PYR-1 NYFGG---------VTEDFHWFERVLDDSGSGLNRPAAVIVETVQGEGGL
TH_3246|M.thermoresistible__bu NYFGG---------VTEDFQWFEKVLDDEGSGLNRPAAVIVETVQGEGGL
*:.: * : **.*
Mb1683|M.bovis_AF2122/97 VVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVV
Rv1655|M.tuberculosis_H37Rv VVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVV
MAV_3115|M.avium_104 VVPPEGYLAAARDITARHGALLVLDEVQTGMGRTGTFFAHQHDGITPDVV
MLBr_00485|M.leprae_Br4923 IVPAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDGIVPDLI
MSMEG_2487|M.smegmatis_MC2_155 VPANERFLAGLRERADAHGILLVLDEVQTGYGRTGKFWGGEHFDAKPDIL
MMAR_0166|M.marinum_M LPAHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMV
MUL_4930|M.ulcerans_Agy99 LPAHPRWAKALRNLANRFEVPLIADEVQAGMFRTGRAWGFEHCDIEPDMV
MAB_1684|M.abscessus_ATCC_1997 IPAPARWGQALRRTASTLGVPLIADEVQAGMYRTGPAWAFQHSGIEPDMM
Mflv_4833|M.gilvum_PYR-GCK NVARMEWLRALAELCQRRDILLIVDDVQMGCGRTGAFFSFEEAGIVPDIV
Mvan_5273|M.vanbaalenii_PYR-1 NVARVEWLRGLAELCQRREILLIVDDVQMGCGRTGPFFSFEEAGIVPDIV
TH_3246|M.thermoresistible__bu NVARAEWLRALAELCHTRDILLIVDDVQMGCGRTGAFFSFEEAGITPDIV
. : :: *:** * *** :. :. . **::
Mb1683|M.bovis_AF2122/97 TLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLR-
Rv1655|M.tuberculosis_H37Rv TLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLR-
MAV_3115|M.avium_104 TLAKGLGGGLPIGACLAVGPAADLLTPGLHGSTFGGNPVCAAAALAVLR-
MLBr_00485|M.leprae_Br4923 CTAKGIADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATIT-
MSMEG_2487|M.smegmatis_MC2_155 VTAKGLASGFPLSGIAASSELMAKAWPGSQGGTYGANAVACAAAIATLD-
MMAR_0166|M.marinum_M VMSKGLG-SGVPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIR-
MUL_4930|M.ulcerans_Agy99 VMSKGLG-SGVPIAVIVVREGYDVWEPGAFTGTFRGNAMAFAAASAVIR-
MAB_1684|M.abscessus_ATCC_1997 VISKGLG-SGIPIAVLVVRKEFDVWEPGAFTGTFRGNAMAFAAASAVIR-
Mflv_4833|M.gilvum_PYR-GCK TLSKSISGYGLPMALTLFRRDLDVWAPGEHNGTFRGHNPAFVTATKALET
Mvan_5273|M.vanbaalenii_PYR-1 TLSKSISGYGLPMALTLFRRQLDVWTPGEHNGTFRGHNPAFVTAAKALET
TH_3246|M.thermoresistible__bu TLSKSISGYGLPMALTLFRRELDVWAPGEHNGTFRGHNPAFVTATAALKT
:*.:. . . .*: .: . .:* .:
Mb1683|M.bovis_AF2122/97 VLASDGLVRRAEVLGKSLRHGIEALG--HPLIDHVRGRGLLLGIALTAP-
Rv1655|M.tuberculosis_H37Rv VLASDGLVRRAEVLGKSLRHGIEALG--HPLIDHVRGRGLLLGIALTAP-
MAV_3115|M.avium_104 VLASENLVRHAEVLGKSLHQGIEGLG--HPLVDHVRGRGLLCGVVLTAP-
MLBr_00485|M.leprae_Br4923 TIENDGLIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVELVKSG
MSMEG_2487|M.smegmatis_MC2_155 VIADENLVANAAERGAQLKQALQTVADKHEQITDVRGLGLMIGNEFRDAD
MMAR_0166|M.marinum_M YAREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQ
MUL_4930|M.ulcerans_Agy99 YAREAALAEHVTRMGEYFRTGLQRILEECEIVGDVRGRGLMLAAEIVDPQ
MAB_1684|M.abscessus_ATCC_1997 FARENGLRGQVTARGKIFLDGLNAVASDSALVGDVRGVGLMLGVEIVDPD
Mflv_4833|M.gilvum_PYR-GCK YWKSATFAENTAAKGQHVRDRLESIAAAHEGIS-ARGRGMAQGLKCEE--
Mvan_5273|M.vanbaalenii_PYR-1 YWETETFVEDTLAKGRRVRERLVGIAGNHPGVT-ARGRGMAQGLKFED--
TH_3246|M.thermoresistible__bu YWQDDSFTAQTVRKGEFLRNELESIAARHEGVS-ARGRGMAQGLKFEQ--
: . . : : : .** * .
Mb1683|M.bovis_AF2122/97 ------------HAKDAEATARDAG---YLVNAAAPDVIRLAPPLIIAEA
Rv1655|M.tuberculosis_H37Rv ------------HAKDAEATARDAG---YLVNAAAPDVIRLAPPLIIAEA
MAV_3115|M.avium_104 ------------RAKDAEAAAREAG---FLVNAAAPGVIRLAPPLIVTEA
MLBr_00485|M.leprae_Br4923 TA------EPDPELTEKVATAAHATGVIILTCGMFGNIIRLLPPLTISDE
MSMEG_2487|M.smegmatis_MC2_155 GK------PDGTTAAAVQQEAARRG-LLLLTCGAWGQVVRFIPALVVSAD
MMAR_0166|M.marinum_M LPWPSGV-APAPELARQIQRASLSNGLIIESGGQYGNVIRFLPPLTIEEA
MUL_4930|M.ulcerans_Agy99 LPWPSGV-APAPELARQIERASLSNGLIIESGGQYGNVIRFLPPLTIEEA
MAB_1684|M.abscessus_ATCC_1997 MPWPDDAGAPAPELAARIQQACLQHGLIVETGGQYGNVVRFLPPLTIDEP
Mflv_4833|M.gilvum_PYR-GCK -----------KDLAAAICATAFERGVLMETSGPSDEVIKLLPPLTTSTE
Mvan_5273|M.vanbaalenii_PYR-1 -----------AAVAGAAAGAAFERGLLVETSGPADEVIKLLPPLTTSEE
TH_3246|M.thermoresistible__bu -----------EDLAGAVCRAAFDRGLLMETSGPSDEVVKLLPPLTMSQE
: . :::: *.*
Mb1683|M.bovis_AF2122/97 QLDGFVAALPAILDRAVGAP-----------
Rv1655|M.tuberculosis_H37Rv QLDGFVAALPAILDRAVGAP-----------
MAV_3115|M.avium_104 QIDGFIAALPGILDRAAA-------------
MLBr_00485|M.leprae_Br4923 LLAEGLDILSRILGDF---------------
MSMEG_2487|M.smegmatis_MC2_155 EVEEAAGIWADAVSAVVS-------------
MMAR_0166|M.marinum_M DISAALTAFEAAVKQVERHRTKAVDLRADQR
MUL_4930|M.ulcerans_Agy99 DISAALTAFEAAVKQVERHRTKAVDLRADQR
MAB_1684|M.abscessus_ATCC_1997 DIAAALNAFDAALSAVERTR-----------
Mflv_4833|M.gilvum_PYR-GCK DLDAGLDILAEAVATTVS-------------
Mvan_5273|M.vanbaalenii_PYR-1 DLDSGIDILAEAIAVTVA-------------
TH_3246|M.thermoresistible__bu ELEAGLGILADAVAATVD-------------
: :