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MSAKRTGDSSAPVVERVPTADGLALAVDLYHCDAPRAVVLLLHGGGQSRHAWDVTAQRLHQRGYTVAAYD TRGHGDSDWDPDGRYDMDRLGSDLLAVRSYADSGRPVAAIGASLGGLTILGTHLLAPPDLWQAVVLVDVT PRMEMDGARRVVAFMSAHPEGFDSLESAADVIAAYNPHRPRPENLDGLRKVLARREDGRWSWRWDPAFVT SNFQFLQGDPDEGAEYFEMMSAFLLDGARQVSAPTLLVRGLLSDIVSEETVRHFLTVVPHAQTVDVSGAG HMIAGDNNDAFSTAVVEFLDRTI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2045 | - | - | 100% (303) | putative hydrolase (alpha/beta fold) |
| M. abscessus ATCC 19977 | MAB_4337 | - | 3e-10 | 37.65% (85) | putative hydrolase, alpha/beta fold |
| M. abscessus ATCC 19977 | MAB_4551c | - | 2e-07 | 34.95% (103) | lysophospholipase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1154c | bpoB | 1e-54 | 42.23% (296) | peroxidase BpoB |
| M. gilvum PYR-GCK | Mflv_4622 | - | 1e-123 | 69.20% (289) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv1123c | bpoB | 1e-54 | 42.23% (296) | peroxidase BpoB |
| M. leprae Br4923 | MLBr_02297 | - | 1e-08 | 26.05% (311) | putative hydrolase |
| M. marinum M | MMAR_3159 | - | 1e-156 | 87.13% (303) | hydrolase |
| M. avium 104 | MAV_1254 | - | 7e-65 | 48.77% (285) | hydrolase, alpha/beta fold family protein |
| M. smegmatis MC2 155 | MSMEG_5209 | - | 7e-62 | 47.90% (286) | hydrolase, alpha/beta fold family protein |
| M. thermoresistible (build 8) | TH_2112 | - | 2e-53 | 45.62% (274) | hydrolase, alpha/beta fold family protein |
| M. ulcerans Agy99 | MUL_0147 | bpoB | 7e-60 | 44.44% (297) | peroxidase BpoB |
| M. vanbaalenii PYR-1 | Mvan_0315 | - | 1e-113 | 65.99% (294) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2045|M.abscessus_ATCC_1997 ----------MSAKRTGDSSAPVVERVPTADGLALAVDLYHCDAP----R
MMAR_3159|M.marinum_M ----------MSANRAHDSSAPVVERVPTVDGLSLAVDFYRCDGP----R
Mflv_4622|M.gilvum_PYR-GCK ------------------MTSTFER-VRNEDGTALAADVYRHESA----R
Mvan_0315|M.vanbaalenii_PYR-1 ------------------MTSAVQHRVRTQDGITLAADCYDHEDA----R
Mb1154c|M.bovis_AF2122/97 MTIWRVPSKVTSGPVSAVSSSPQAVAFSGARGITLVADEWNRGAA-AADR
Rv1123c|M.tuberculosis_H37Rv MTIWRVPSKVTSGPVSAVSSSPQAVAFSGARGITLVADEWNRGAA-AADR
MUL_0147|M.ulcerans_Agy99 --------------MSAMSNNPRTVEFSGTEGITLVADEWNRDTA-ASGR
MAV_1254|M.avium_104 ------------------------MEFAGVDGITLVADEWNRGSD-GAGR
MSMEG_5209|M.smegmatis_MC2_155 --------------MSTAQTESQTVAFRGVDDLTLVGDEWNKGAERAADR
TH_2112|M.thermoresistible__bu --------------LNSTHSKPQTVRFRGAQGLTLVADQWNRGSG-PKDR
MLBr_02297|M.leprae_Br4923 MAMSNPSVTRIAGPWHHLDVHANGIRFHVVEAVPTQPAGQDCAPS-ATAR
. . *
MAB_2045|M.abscessus_ATCC_1997 AVVLLLHGGGQSRHAWDVTAQRLHQRGYTVAAYDTRGHGDSDWDPDGRYD
MMAR_3159|M.marinum_M AVVLLLHGGGQSRHAWDVTAQRLHQRGYTVAAYDARGHGDSDWDPDGRYD
Mflv_4622|M.gilvum_PYR-GCK AVVILLHGGGQNRHAWATTARRLHARGYTVVAYDARGHGDSEWDPDGRYD
Mvan_0315|M.vanbaalenii_PYR-1 PVVLLLHGGGQNRHAWSASARRLHACGYTVVAYDTRGHGDSDWDPAGRYD
Mb1154c|M.bovis_AF2122/97 PTILMLHGGGQNRFSWKNTGQILADEGHHVVALDTRGPGDSDRAPGADYA
Rv1123c|M.tuberculosis_H37Rv PTILMLHGGGQNRFSWKNTGQILADEGHHVVALDTRGPGDSDRAPGADYA
MUL_0147|M.ulcerans_Agy99 PTILMLHGGCQNRFSWKNTGQILADTGLHVIALDTRGHGDSDRAPDADYA
MAV_1254|M.avium_104 PSILMLHGGGQNRFSWKNTGQTLADEGLHVVALDSRGHGDSDRSPQADYQ
MSMEG_5209|M.smegmatis_MC2_155 PTVLLLHGGGQNRYSWKNTGQILADQGFHVIALDARGHGDSDRSPSANYS
TH_2112|M.thermoresistible__bu PTILLLHGGGQNRFSWKNTGQILADKGWHVVALDSRGHGDSDRSPTADYQ
MLBr_02297|M.leprae_Br4923 PLVMLLHGFGSFWWSWRHQLRGLTEA--RLVAVDLRGYGGSDKPPRG-YD
. :::*** . :* : * : * * ** *.*: * . *
MAB_2045|M.abscessus_ATCC_1997 MDRLGSDLLAVRSYADSGRPVAAIGASLGGLTILGTHLLAPPDLWQAVVL
MMAR_3159|M.marinum_M IERLGSDLLAVRAYAGSARPVAAIGASLGGLTILGTHLLAPSELWQAVVL
Mflv_4622|M.gilvum_PYR-GCK LDRLASDLLSIRRYASDGRPPAVVGASLGGMTVLGTHLVAPADLWGAVVL
Mvan_0315|M.vanbaalenii_PYR-1 LERLATDLLAVREHFSAATAPAVVGASLGGMTVLGTHLLTSGASWAAVVL
Mb1154c|M.bovis_AF2122/97 VETPTTDVLHVVEAIG--RRVVVVEASMGGLTGILVAERAGPQTVNGLVL
Rv1123c|M.tuberculosis_H37Rv VETPTTDVLHVVEAIG--RRVVVVEASMGGLTGILVAERAGPQTVNGLVL
MUL_0147|M.ulcerans_Agy99 IETLTSDIRHVLDAIG--RPVVLIGASMGGLTGILVADSAGPDRVTGLVL
MAV_1254|M.avium_104 IETLTADVLRVLDAIG--RPVTIIGASMGGLTGILAAHRAGPAKVTRLVL
MSMEG_5209|M.smegmatis_MC2_155 VDAMCGDVLAVLYQIS--RPVALIGASMGGLTGLLAAHEAGPERVTQLVL
TH_2112|M.thermoresistible__bu LDDLCADTLSVVDQIG--RPVSLIGASMGGLTGILVADRAGADKVTELVL
MLBr_02297|M.leprae_Br4923 GWTLAGDTAGLIRALG-HSSATLVGHAEGGLACWATALLHP-RLVRAIAL
* : . : : **:: . :.*
MAB_2045|M.abscessus_ATCC_1997 VDVTPRMEMDGARRVVAFMSAHPEGFDSLESAADVIAAYNPHRPRPEN-L
MMAR_3159|M.marinum_M VDITPRMQMHGARRVLSFMSAHPEGFDSLESAADVIAAYNPHRPRPEN-V
Mflv_4622|M.gilvum_PYR-GCK VDITPRMEFHGARRVVSFMGAHPDGFDTLDAAADVIAQYNRHRARPKN-L
Mvan_0315|M.vanbaalenii_PYR-1 VDVTPRLEFQGARRVVTFMAAHPDGFGTLTDAAEVIAAYNPHRSRPAN-V
Mb1154c|M.bovis_AF2122/97 VDVVPRYEKEGNARIRDFMLGNIDGFGSLEEAADAVAEYLPHRDKPRS-P
Rv1123c|M.tuberculosis_H37Rv VDVVPRYEKEGNARIRDFMLGNIDGFGSLEEAADAVAEYLPHRDKPRS-P
MUL_0147|M.ulcerans_Agy99 VDVVPKYEKDGSARIRDFMFTNLHGFATLEEAADAVATYLPHRTKPRS-P
MAV_1254|M.avium_104 VDVVPRFEKDGSARIRDFMISGLDGFDSLEQAADAVAAYLPYRSKPRS-P
MSMEG_5209|M.smegmatis_MC2_155 VDVVPNFEKSGSARIRDFMASNVDGFDTLEEAADAVAAYLPHRRRPRN-P
TH_2112|M.thermoresistible__bu VDVVPRVEQAGTDRIRDFMMTNVAGFETLEEAADAVAAYLPHRRRPRS-P
MLBr_02297|M.leprae_Br4923 INSP-----HPAALRRSMLTHRNQGYALLPTLLRYQLPIWPERLLTRNNA
:: :: *: * * . .
MAB_2045|M.abscessus_ATCC_1997 DGLRKVLARREDGRWSWRWDPAFVTSNFQFLQGDPDEGAEYFEMMSAFL-
MMAR_3159|M.marinum_M DGLQKVLRRRGDGRWAWRWDPAFATSNFQFLQSDSDDGAEEFEMMSAFL-
Mflv_4622|M.gilvum_PYR-GCK DGLRKVLQQRDDGRWIWRWDPAFIASNFEFLQGDPATGAKEFGAISDLL-
Mvan_0315|M.vanbaalenii_PYR-1 DGLRKVLRQRHDGRWIWRWDPAFIHSNFDFLRDESTTGTEQFDAISHLL-
Mb1154c|M.bovis_AF2122/97 EGLKRNLRLR-DGRWHWHWDPAMMT----APGHDPQLRTENFERA-----
Rv1123c|M.tuberculosis_H37Rv EGLKRNLRLR-DGRWHWHWDPAMMT----APGHDPQLRTENFERA-----
MUL_0147|M.ulcerans_Agy99 EGLKKNLRLR-DGRWYWHWDPAMMT----APGDDPELRTENFERA-----
MAV_1254|M.avium_104 EGLKKNLRLR-DGRWYWHWDPAFMT----KPGDDPELRTESFEQA-----
MSMEG_5209|M.smegmatis_MC2_155 EGLKKNLRLR-DGRWYWHWDPAFLG----KPHDDPFVRVERLEQA-----
TH_2112|M.thermoresistible__bu EGLKKNLRHR-DGRWHWHWDPAFVT----RVG-EQFVDVDVLERA-----
MLBr_02297|M.leprae_Br4923 AEIERLVRSRSSAKWQACEDFAVTIDHLRIAIQIPAAAHCALEYQRWAVR
:.: : * ..:* * *. :
MAB_2045|M.abscessus_ATCC_1997 -----------LDGARQVSAPTLLVRGLLSDIVSEETVRHFLTVVPHAQT
MMAR_3159|M.marinum_M -----------VDGARQVSAPALLVRGLLSDIVSEETVKDFLTLVPHAQT
Mflv_4622|M.gilvum_PYR-GCK -----------IEGARRVRAPTLLIRGVHSDVTSQQSVEEFLEVVPHAEA
Mvan_0315|M.vanbaalenii_PYR-1 -----------IDGARRVSAPTLLVRGLLSDVVSQATVDEFQQLVPHAET
Mb1154c|M.bovis_AF2122/97 --------------AMGLTIPVLLIRGKLSDVVSSDGARDFLAKVPNAEF
Rv1123c|M.tuberculosis_H37Rv --------------AMGLTIPVLLIRGKLSDVVSSDGARDFLAKVPNAEF
MUL_0147|M.ulcerans_Agy99 --------------AMNLTIPILLIRGKLSDVVTSEGVQDFLDKVPHAEF
MAV_1254|M.avium_104 --------------AKNLSIPVLLIRGKLSDVVSPEGVRHFLATVPRAEF
MSMEG_5209|M.smegmatis_MC2_155 --------------AVNLTVPILLIRGKLSDVVSPEGVAEFLEKVPAAEF
TH_2112|M.thermoresistible__bu --------------ALRLTVPILLVRGKLSDVVSAEGVEEFLAKVPSAEF
MLBr_02297|M.leprae_Br4923 SQLRNEGRKFMKSMSRPFSVPLLHVRGDADPYLLADSVDRTRRYAPHGRY
: . * * :** . . .* ..
MAB_2045|M.abscessus_ATCC_1997 VDVSGAGHMIAGDNNDAFSTAVVEFLDRTI--------------------
MMAR_3159|M.marinum_M VDVSGAGHMVAGDNNDAFSTAVVDFLDRTV--------------------
Mflv_4622|M.gilvum_PYR-GCK VDVSGTGHMVAGDDNDAFTSAVADFLDRTLNDSSD---------------
Mvan_0315|M.vanbaalenii_PYR-1 VDVSGTGHMIAGDDNDAFSSAVTEFLGRSILQPPP---------------
Mb1154c|M.bovis_AF2122/97 VELSNAGRTAAGDDNDAFTDVVVDFVRRLS--------------------
Rv1123c|M.tuberculosis_H37Rv VELSNAGRTAAGDDNDAFTDVVVDFVRRLS--------------------
MUL_0147|M.ulcerans_Agy99 VELSNAGHTAAGDDNDAFTEVVVDFVKRRAATG-----------------
MAV_1254|M.avium_104 VELSNAGHTAAGDDNDAFSDAVVAFVKRR---------------------
MSMEG_5209|M.smegmatis_MC2_155 VELSDAGHTAAGDDNDAFTQVVVEFVNR----------------------
TH_2112|M.thermoresistible__bu VELSAAXXXATIPARGSPRRCVTSPVCRRRPPTSRPAPSPRSAPRHGNVA
MLBr_02297|M.leprae_Br4923 VSVSDAGHFSHEEAPEEINRYLTRFLKQVHGPRLS---------------
*.:* : :. : :
MAB_2045|M.abscessus_ATCC_1997 ---------
MMAR_3159|M.marinum_M ---------
Mflv_4622|M.gilvum_PYR-GCK ---------
Mvan_0315|M.vanbaalenii_PYR-1 ---------
Mb1154c|M.bovis_AF2122/97 ---------
Rv1123c|M.tuberculosis_H37Rv ---------
MUL_0147|M.ulcerans_Agy99 ---------
MAV_1254|M.avium_104 ---------
MSMEG_5209|M.smegmatis_MC2_155 ---------
TH_2112|M.thermoresistible__bu GPGANAVRR
MLBr_02297|M.leprae_Br4923 ---------