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MTIWRVPSKVTSGPVSAVSSSPQAVAFSGARGITLVADEWNRGAAAADRPTILMLHGGGQNRFSWKNTGQ ILADEGHHVVALDTRGPGDSDRAPGADYAVETPTTDVLHVVEAIGRRVVVVEASMGGLTGILVAERAGPQ TVNGLVLVDVVPRYEKEGNARIRDFMLGNIDGFGSLEEAADAVAEYLPHRDKPRSPEGLKRNLRLRDGRW HWHWDPAMMTAPGHDPQLRTENFERAAMGLTIPVLLIRGKLSDVVSSDGARDFLAKVPNAEFVELSNAGR TAAGDDNDAFTDVVVDFVRRLS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1154c | bpoB | - | 100% (302) | peroxidase BpoB |
M. bovis AF2122 / 97 | Mb3502c | bpoA | 4e-52 | 38.67% (256) | peroxidase BpoA |
M. bovis AF2122 / 97 | Mb0046c | - | 1e-13 | 26.79% (280) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_2096 | - | 1e-108 | 66.21% (290) | alpha/beta hydrolase fold |
M. tuberculosis H37Rv | Rv1123c | bpoB | 1e-175 | 100.00% (302) | peroxidase BpoB |
M. leprae Br4923 | MLBr_02297 | - | 3e-05 | 20.57% (282) | putative hydrolase |
M. abscessus ATCC 19977 | MAB_2045 | - | 1e-54 | 42.23% (296) | putative hydrolase (alpha/beta fold) |
M. marinum M | MMAR_4337 | bpoB | 1e-134 | 80.07% (286) | peroxidase BpoB |
M. avium 104 | MAV_1254 | - | 1e-121 | 75.72% (276) | hydrolase, alpha/beta fold family protein |
M. smegmatis MC2 155 | MSMEG_5209 | - | 1e-111 | 67.25% (287) | hydrolase, alpha/beta fold family protein |
M. thermoresistible (build 8) | TH_2112 | - | 1e-100 | 66.42% (268) | hydrolase, alpha/beta fold family protein |
M. ulcerans Agy99 | MUL_0147 | bpoB | 1e-132 | 79.02% (286) | peroxidase BpoB |
M. vanbaalenii PYR-1 | Mvan_4609 | - | 1e-108 | 64.97% (294) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment Mb1154c|M.bovis_AF2122/97 MTIWRVPSKVTSGPVSAVSSSPQAVAFSGARGITLVADEWNRGAAAAD-- Rv1123c|M.tuberculosis_H37Rv MTIWRVPSKVTSGPVSAVSSSPQAVAFSGARGITLVADEWNRGAAAAD-- MMAR_4337|M.marinum_M --------------MSAMSNNPRTVEFSGTEGITLVADEWNRDTAASG-- MUL_0147|M.ulcerans_Agy99 --------------MSAMSNNPRTVEFSGTEGITLVADEWNRDTAASG-- MAV_1254|M.avium_104 ------------------------MEFAGVDGITLVADEWNRGSDGAG-- Mflv_2096|M.gilvum_PYR-GCK --------------MSIEHREPKTVTFRGADGLALVADEWNNPAQTEA-- Mvan_4609|M.vanbaalenii_PYR-1 --------------MSTVSSEPTTVTFRGAEDLALVADEWNNPAEAASSG MSMEG_5209|M.smegmatis_MC2_155 --------------MSTAQTESQTVAFRGVDDLTLVGDEWNKGAERAA-- TH_2112|M.thermoresistible__bu --------------LNSTHSKPQTVRFRGAQGLTLVADQWNRGSGPKD-- MAB_2045|M.abscessus_ATCC_1997 ----------MSAKRTGDSSAPVVERVPTADGLALAVDLYHCDAP----- MLBr_02297|M.leprae_Br4923 MAMSNPSVTRIAGPWHHLDVHANGIRFHVVEAVPTQPAGQDCAPSATA-- . . :. . . Mb1154c|M.bovis_AF2122/97 ------RPTILMLHGGGQNRFSWKNTGQILADEGHHVVALDTRGPGDSDR Rv1123c|M.tuberculosis_H37Rv ------RPTILMLHGGGQNRFSWKNTGQILADEGHHVVALDTRGPGDSDR MMAR_4337|M.marinum_M ------RPTILMLHGGGQNRFSWKNTGQILADTGLHVIALDTRGHGDSDR MUL_0147|M.ulcerans_Agy99 ------RPTILMLHGGCQNRFSWKNTGQILADTGLHVIALDTRGHGDSDR MAV_1254|M.avium_104 ------RPSILMLHGGGQNRFSWKNTGQTLADEGLHVVALDSRGHGDSDR Mflv_2096|M.gilvum_PYR-GCK --FDRSRPSVLMMHGGGQNRFSWKKTGQILGEQGLHVVALDSRGHGDSDR Mvan_4609|M.vanbaalenii_PYR-1 RDFDASRPSVLMLHGGGQNRFSWKKTGQTLASQGLHVVALDSRGHGDSDR MSMEG_5209|M.smegmatis_MC2_155 -----DRPTVLLLHGGGQNRYSWKNTGQILADQGFHVIALDARGHGDSDR TH_2112|M.thermoresistible__bu ------RPTILLLHGGGQNRFSWKNTGQILADKGWHVVALDSRGHGDSDR MAB_2045|M.abscessus_ATCC_1997 ------RAVVLLLHGGGQSRHAWDVTAQRLHQRGYTVAAYDTRGHGDSDW MLBr_02297|M.leprae_Br4923 ------RPLVMLLHGFGSFWWSWRHQLRGLTEA--RLVAVDLRGYGGSDK *. ::::** . :* : * . : * * ** *.** Mb1154c|M.bovis_AF2122/97 APGADYAVETPTTDVLHV--VEAIGRRVVVVEASMGGLTGILVAERAGPQ Rv1123c|M.tuberculosis_H37Rv APGADYAVETPTTDVLHV--VEAIGRRVVVVEASMGGLTGILVAERAGPQ MMAR_4337|M.marinum_M APDADYAIETLTSDILHV--LDAIGRPVVLIGASMGGLTGILVADSAGPD MUL_0147|M.ulcerans_Agy99 APDADYAIETLTSDIRHV--LDAIGRPVVLIGASMGGLTGILVADSAGPD MAV_1254|M.avium_104 SPQADYQIETLTADVLRV--LDAIGRPVTIIGASMGGLTGILAAHRAGPA Mflv_2096|M.gilvum_PYR-GCK SPDARYTVEALCEDTLRV--LEQIGRPTVLIGASMGGLTGILAARRAGPE Mvan_4609|M.vanbaalenii_PYR-1 SPDANYTVEALCADTLAV--LRQIGRPTVLIGASMGGLTGILASRQAGPE MSMEG_5209|M.smegmatis_MC2_155 SPSANYSVDAMCGDVLAV--LYQISRPVALIGASMGGLTGLLAAHEAGPE TH_2112|M.thermoresistible__bu SPTADYQLDDLCADTLSV--VDQIGRPVSLIGASMGGLTGILVADRAGAD MAB_2045|M.abscessus_ATCC_1997 DPDGRYDMDRLGSDLLAVRSYADSGRPVAAIGASLGGLTILGTHLLAPPD MLBr_02297|M.leprae_Br4923 PPRG-YDGWTLAGDTAGL--IRALGHSSATLVGHAEGGLACWATALLHPR * . * * : .: : . * . . Mb1154c|M.bovis_AF2122/97 TVNGLVLVDVVPRYEKEGNARIRDFMLGNIDGFGSLEEAADAVAEYLPHR Rv1123c|M.tuberculosis_H37Rv TVNGLVLVDVVPRYEKEGNARIRDFMLGNIDGFGSLEEAADAVAEYLPHR MMAR_4337|M.marinum_M RVTGLVLVDVVPKYEKDGSARIRDFMFTNLHGFATLEEAADAVATYLPHR MUL_0147|M.ulcerans_Agy99 RVTGLVLVDVVPKYEKDGSARIRDFMFTNLHGFATLEEAADAVATYLPHR MAV_1254|M.avium_104 KVTRLVLVDVVPRFEKDGSARIRDFMISGLDGFDSLEQAADAVAAYLPYR Mflv_2096|M.gilvum_PYR-GCK VVTRLVLVDVVPRYEKGGSARIRDFMFSHVHGFDSLEQAADAVAEYLPHR Mvan_4609|M.vanbaalenii_PYR-1 LVTRLILVDVVPRYEKDGSARIREFMFSHVHGFESLEQAAEAVAAYLPHR MSMEG_5209|M.smegmatis_MC2_155 RVTQLVLVDVVPNFEKSGSARIRDFMASNVDGFDTLEEAADAVAAYLPHR TH_2112|M.thermoresistible__bu KVTELVLVDVVPRVEQAGTDRIRDFMMTNVAGFETLEEAADAVAAYLPHR MAB_2045|M.abscessus_ATCC_1997 LWQAVVLVDVTPRMEMDGARRVVAFMSAHPEGFDSLESAADVIAAYNPHR MLBr_02297|M.leprae_Br4923 LVRAIALINSP-----HPAALRRSMLTHRNQGYALLPTLLRYQLPIWPER : *:: :: *: * * * Mb1154c|M.bovis_AF2122/97 DKPRS-PEGLKRNLRLR-DGRWHWHWDPAMMT----APGHDPQLRTENFE Rv1123c|M.tuberculosis_H37Rv DKPRS-PEGLKRNLRLR-DGRWHWHWDPAMMT----APGHDPQLRTENFE MMAR_4337|M.marinum_M TKPRS-PEGLKKNLRLR-DGRWYWHWDPAMMT----APGDDPELRTENFE MUL_0147|M.ulcerans_Agy99 TKPRS-PEGLKKNLRLR-DGRWYWHWDPAMMT----APGDDPELRTENFE MAV_1254|M.avium_104 SKPRS-PEGLKKNLRLR-DGRWYWHWDPAFMT----KPGDDPELRTESFE Mflv_2096|M.gilvum_PYR-GCK AKPRS-PEGLKKNLRRR-NGRWYWHWDPAFLT----KPSEDPFARVEQLE Mvan_4609|M.vanbaalenii_PYR-1 TKPRS-PEGLKKNLRHR-HGRWYWHWDPAFLT----KPNEDPFVRVEQLE MSMEG_5209|M.smegmatis_MC2_155 RRPRN-PEGLKKNLRLR-DGRWYWHWDPAFLG----KPHDDPFVRVERLE TH_2112|M.thermoresistible__bu RRPRS-PEGLKKNLRHR-DGRWHWHWDPAFVT----RVG-EQFVDVDVLE MAB_2045|M.abscessus_ATCC_1997 PRPEN-LDGLRKVLARREDGRWSWRWDPAFVTSNFQFLQGDPDEGAEYFE MLBr_02297|M.leprae_Br4923 LLTRNNAAEIERLVRSRSSAKWQACEDFAVTIDHLRIAIQIPAAAHCALE ... :.: : * .:* * *. :* Mb1154c|M.bovis_AF2122/97 RA-------------------AMGLTIPVLLIRGKLSDVVSSDGARDFLA Rv1123c|M.tuberculosis_H37Rv RA-------------------AMGLTIPVLLIRGKLSDVVSSDGARDFLA MMAR_4337|M.marinum_M RA-------------------AMNLTIPILLIRGKLSDVVSSEGVQDFLD MUL_0147|M.ulcerans_Agy99 RA-------------------AMNLTIPILLIRGKLSDVVTSEGVQDFLD MAV_1254|M.avium_104 QA-------------------AKNLSIPVLLIRGKLSDVVSPEGVRHFLA Mflv_2096|M.gilvum_PYR-GCK QA-------------------ATELTVPILLIRGKLSDVVSEEAVQDFLA Mvan_4609|M.vanbaalenii_PYR-1 QA-------------------AIELTIPILLIRGKLSDVVSEEAVQDFLT MSMEG_5209|M.smegmatis_MC2_155 QA-------------------AVNLTVPILLIRGKLSDVVSPEGVAEFLE TH_2112|M.thermoresistible__bu RA-------------------ALRLTVPILLVRGKLSDVVSAEGVEEFLA MAB_2045|M.abscessus_ATCC_1997 MMSAFL------------LDGARQVSAPTLLVRGLLSDIVSEETVRHFLT MLBr_02297|M.leprae_Br4923 YQRWAVRSQLRNEGRKFMKSMSRPFSVPLLHVRGDADPYLLADSVDRTRR : .: * * :** . : : . Mb1154c|M.bovis_AF2122/97 KVPNAEFVELSNAGRTAAGDDNDAFTDVVVDFVRRLS------------- Rv1123c|M.tuberculosis_H37Rv KVPNAEFVELSNAGRTAAGDDNDAFTDVVVDFVRRLS------------- MMAR_4337|M.marinum_M KVPHAEFVELSNAGHTAAGDDNDAFTEVVVDFVKRRAATG---------- MUL_0147|M.ulcerans_Agy99 KVPHAEFVELSNAGHTAAGDDNDAFTEVVVDFVKRRAATG---------- MAV_1254|M.avium_104 TVPRAEFVELSNAGHTAAGDDNDAFSDAVVAFVKRR-------------- Mflv_2096|M.gilvum_PYR-GCK KVPGAEFAELSGAGHTAAGDDNDAFSEVVTRFVLR--------------- Mvan_4609|M.vanbaalenii_PYR-1 KVPNAEFVELPGAGHTAAGDDNDAFSEVVAQFVLR--------------- MSMEG_5209|M.smegmatis_MC2_155 KVPAAEFVELSDAGHTAAGDDNDAFTQVVVEFVNR--------------- TH_2112|M.thermoresistible__bu KVPSAEFVELSAAXXXATIPARGSPRRCVTSPVCRRRPPTSRPAPSPRSA MAB_2045|M.abscessus_ATCC_1997 VVPHAQTVDVSGAGHMIAGDNNDAFSTAVVEFLDRTI------------- MLBr_02297|M.leprae_Br4923 YAPHGRYVSVSDAGHFSHEEAPEEINRYLTRFLKQVHGPRLS-------- .* .. ..:. * :. : : Mb1154c|M.bovis_AF2122/97 ---------------- Rv1123c|M.tuberculosis_H37Rv ---------------- MMAR_4337|M.marinum_M ---------------- MUL_0147|M.ulcerans_Agy99 ---------------- MAV_1254|M.avium_104 ---------------- Mflv_2096|M.gilvum_PYR-GCK ---------------- Mvan_4609|M.vanbaalenii_PYR-1 ---------------- MSMEG_5209|M.smegmatis_MC2_155 ---------------- TH_2112|M.thermoresistible__bu PRHGNVAGPGANAVRR MAB_2045|M.abscessus_ATCC_1997 ---------------- MLBr_02297|M.leprae_Br4923 ----------------