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M. bovis AF2122 / 97 Mb1154c (bpoB)

annotation: peroxidase BpoB
coordinates: 1247515 - 1248423
length: 302

MTIWRVPSKVTSGPVSAVSSSPQAVAFSGARGITLVADEWNRGAAAADRPTILMLHGGGQNRFSWKNTGQ
ILADEGHHVVALDTRGPGDSDRAPGADYAVETPTTDVLHVVEAIGRRVVVVEASMGGLTGILVAERAGPQ
TVNGLVLVDVVPRYEKEGNARIRDFMLGNIDGFGSLEEAADAVAEYLPHRDKPRSPEGLKRNLRLRDGRW
HWHWDPAMMTAPGHDPQLRTENFERAAMGLTIPVLLIRGKLSDVVSSDGARDFLAKVPNAEFVELSNAGR
TAAGDDNDAFTDVVVDFVRRLS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1154cbpoB-100% (302)peroxidase BpoB
M. bovis AF2122 / 97Mb3502cbpoA4e-5238.67% (256) peroxidase BpoA
M. bovis AF2122 / 97Mb0046c-1e-1326.79% (280) hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2096-1e-10866.21% (290) alpha/beta hydrolase fold
M. tuberculosis H37RvRv1123cbpoB1e-175100.00% (302) peroxidase BpoB
M. leprae Br4923MLBr_02297-3e-0520.57% (282) putative hydrolase
M. abscessus ATCC 19977MAB_2045-1e-5442.23% (296) putative hydrolase (alpha/beta fold)
M. marinum MMMAR_4337bpoB1e-13480.07% (286) peroxidase BpoB
M. avium 104MAV_1254-1e-12175.72% (276) hydrolase, alpha/beta fold family protein
M. smegmatis MC2 155MSMEG_5209-1e-11167.25% (287) hydrolase, alpha/beta fold family protein
M. thermoresistible (build 8)TH_2112-1e-10066.42% (268) hydrolase, alpha/beta fold family protein
M. ulcerans Agy99MUL_0147bpoB1e-13279.02% (286) peroxidase BpoB
M. vanbaalenii PYR-1Mvan_4609-1e-10864.97% (294) alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


Mb1154c|M.bovis_AF2122/97           MTIWRVPSKVTSGPVSAVSSSPQAVAFSGARGITLVADEWNRGAAAAD--
Rv1123c|M.tuberculosis_H37Rv        MTIWRVPSKVTSGPVSAVSSSPQAVAFSGARGITLVADEWNRGAAAAD--
MMAR_4337|M.marinum_M               --------------MSAMSNNPRTVEFSGTEGITLVADEWNRDTAASG--
MUL_0147|M.ulcerans_Agy99           --------------MSAMSNNPRTVEFSGTEGITLVADEWNRDTAASG--
MAV_1254|M.avium_104                ------------------------MEFAGVDGITLVADEWNRGSDGAG--
Mflv_2096|M.gilvum_PYR-GCK          --------------MSIEHREPKTVTFRGADGLALVADEWNNPAQTEA--
Mvan_4609|M.vanbaalenii_PYR-1       --------------MSTVSSEPTTVTFRGAEDLALVADEWNNPAEAASSG
MSMEG_5209|M.smegmatis_MC2_155      --------------MSTAQTESQTVAFRGVDDLTLVGDEWNKGAERAA--
TH_2112|M.thermoresistible__bu      --------------LNSTHSKPQTVRFRGAQGLTLVADQWNRGSGPKD--
MAB_2045|M.abscessus_ATCC_1997      ----------MSAKRTGDSSAPVVERVPTADGLALAVDLYHCDAP-----
MLBr_02297|M.leprae_Br4923          MAMSNPSVTRIAGPWHHLDVHANGIRFHVVEAVPTQPAGQDCAPSATA--
                                                              .  .  :.      .  .      

Mb1154c|M.bovis_AF2122/97           ------RPTILMLHGGGQNRFSWKNTGQILADEGHHVVALDTRGPGDSDR
Rv1123c|M.tuberculosis_H37Rv        ------RPTILMLHGGGQNRFSWKNTGQILADEGHHVVALDTRGPGDSDR
MMAR_4337|M.marinum_M               ------RPTILMLHGGGQNRFSWKNTGQILADTGLHVIALDTRGHGDSDR
MUL_0147|M.ulcerans_Agy99           ------RPTILMLHGGCQNRFSWKNTGQILADTGLHVIALDTRGHGDSDR
MAV_1254|M.avium_104                ------RPSILMLHGGGQNRFSWKNTGQTLADEGLHVVALDSRGHGDSDR
Mflv_2096|M.gilvum_PYR-GCK          --FDRSRPSVLMMHGGGQNRFSWKKTGQILGEQGLHVVALDSRGHGDSDR
Mvan_4609|M.vanbaalenii_PYR-1       RDFDASRPSVLMLHGGGQNRFSWKKTGQTLASQGLHVVALDSRGHGDSDR
MSMEG_5209|M.smegmatis_MC2_155      -----DRPTVLLLHGGGQNRYSWKNTGQILADQGFHVIALDARGHGDSDR
TH_2112|M.thermoresistible__bu      ------RPTILLLHGGGQNRFSWKNTGQILADKGWHVVALDSRGHGDSDR
MAB_2045|M.abscessus_ATCC_1997      ------RAVVLLLHGGGQSRHAWDVTAQRLHQRGYTVAAYDTRGHGDSDW
MLBr_02297|M.leprae_Br4923          ------RPLVMLLHGFGSFWWSWRHQLRGLTEA--RLVAVDLRGYGGSDK
                                          *. ::::**  .   :*    : * .    : * * ** *.** 

Mb1154c|M.bovis_AF2122/97           APGADYAVETPTTDVLHV--VEAIGRRVVVVEASMGGLTGILVAERAGPQ
Rv1123c|M.tuberculosis_H37Rv        APGADYAVETPTTDVLHV--VEAIGRRVVVVEASMGGLTGILVAERAGPQ
MMAR_4337|M.marinum_M               APDADYAIETLTSDILHV--LDAIGRPVVLIGASMGGLTGILVADSAGPD
MUL_0147|M.ulcerans_Agy99           APDADYAIETLTSDIRHV--LDAIGRPVVLIGASMGGLTGILVADSAGPD
MAV_1254|M.avium_104                SPQADYQIETLTADVLRV--LDAIGRPVTIIGASMGGLTGILAAHRAGPA
Mflv_2096|M.gilvum_PYR-GCK          SPDARYTVEALCEDTLRV--LEQIGRPTVLIGASMGGLTGILAARRAGPE
Mvan_4609|M.vanbaalenii_PYR-1       SPDANYTVEALCADTLAV--LRQIGRPTVLIGASMGGLTGILASRQAGPE
MSMEG_5209|M.smegmatis_MC2_155      SPSANYSVDAMCGDVLAV--LYQISRPVALIGASMGGLTGLLAAHEAGPE
TH_2112|M.thermoresistible__bu      SPTADYQLDDLCADTLSV--VDQIGRPVSLIGASMGGLTGILVADRAGAD
MAB_2045|M.abscessus_ATCC_1997      DPDGRYDMDRLGSDLLAVRSYADSGRPVAAIGASLGGLTILGTHLLAPPD
MLBr_02297|M.leprae_Br4923          PPRG-YDGWTLAGDTAGL--IRALGHSSATLVGHAEGGLACWATALLHPR
                                     * . *       *   :      .:    : .   *     .     . 

Mb1154c|M.bovis_AF2122/97           TVNGLVLVDVVPRYEKEGNARIRDFMLGNIDGFGSLEEAADAVAEYLPHR
Rv1123c|M.tuberculosis_H37Rv        TVNGLVLVDVVPRYEKEGNARIRDFMLGNIDGFGSLEEAADAVAEYLPHR
MMAR_4337|M.marinum_M               RVTGLVLVDVVPKYEKDGSARIRDFMFTNLHGFATLEEAADAVATYLPHR
MUL_0147|M.ulcerans_Agy99           RVTGLVLVDVVPKYEKDGSARIRDFMFTNLHGFATLEEAADAVATYLPHR
MAV_1254|M.avium_104                KVTRLVLVDVVPRFEKDGSARIRDFMISGLDGFDSLEQAADAVAAYLPYR
Mflv_2096|M.gilvum_PYR-GCK          VVTRLVLVDVVPRYEKGGSARIRDFMFSHVHGFDSLEQAADAVAEYLPHR
Mvan_4609|M.vanbaalenii_PYR-1       LVTRLILVDVVPRYEKDGSARIREFMFSHVHGFESLEQAAEAVAAYLPHR
MSMEG_5209|M.smegmatis_MC2_155      RVTQLVLVDVVPNFEKSGSARIRDFMASNVDGFDTLEEAADAVAAYLPHR
TH_2112|M.thermoresistible__bu      KVTELVLVDVVPRVEQAGTDRIRDFMMTNVAGFETLEEAADAVAAYLPHR
MAB_2045|M.abscessus_ATCC_1997      LWQAVVLVDVTPRMEMDGARRVVAFMSAHPEGFDSLESAADVIAAYNPHR
MLBr_02297|M.leprae_Br4923          LVRAIALINSP-----HPAALRRSMLTHRNQGYALLPTLLRYQLPIWPER
                                        : *::               ::     *:  *           * *

Mb1154c|M.bovis_AF2122/97           DKPRS-PEGLKRNLRLR-DGRWHWHWDPAMMT----APGHDPQLRTENFE
Rv1123c|M.tuberculosis_H37Rv        DKPRS-PEGLKRNLRLR-DGRWHWHWDPAMMT----APGHDPQLRTENFE
MMAR_4337|M.marinum_M               TKPRS-PEGLKKNLRLR-DGRWYWHWDPAMMT----APGDDPELRTENFE
MUL_0147|M.ulcerans_Agy99           TKPRS-PEGLKKNLRLR-DGRWYWHWDPAMMT----APGDDPELRTENFE
MAV_1254|M.avium_104                SKPRS-PEGLKKNLRLR-DGRWYWHWDPAFMT----KPGDDPELRTESFE
Mflv_2096|M.gilvum_PYR-GCK          AKPRS-PEGLKKNLRRR-NGRWYWHWDPAFLT----KPSEDPFARVEQLE
Mvan_4609|M.vanbaalenii_PYR-1       TKPRS-PEGLKKNLRHR-HGRWYWHWDPAFLT----KPNEDPFVRVEQLE
MSMEG_5209|M.smegmatis_MC2_155      RRPRN-PEGLKKNLRLR-DGRWYWHWDPAFLG----KPHDDPFVRVERLE
TH_2112|M.thermoresistible__bu      RRPRS-PEGLKKNLRHR-DGRWHWHWDPAFVT----RVG-EQFVDVDVLE
MAB_2045|M.abscessus_ATCC_1997      PRPEN-LDGLRKVLARREDGRWSWRWDPAFVTSNFQFLQGDPDEGAEYFE
MLBr_02297|M.leprae_Br4923          LLTRNNAAEIERLVRSRSSAKWQACEDFAVTIDHLRIAIQIPAAAHCALE
                                      ...    :.: :  *  .:*    * *.                  :*

Mb1154c|M.bovis_AF2122/97           RA-------------------AMGLTIPVLLIRGKLSDVVSSDGARDFLA
Rv1123c|M.tuberculosis_H37Rv        RA-------------------AMGLTIPVLLIRGKLSDVVSSDGARDFLA
MMAR_4337|M.marinum_M               RA-------------------AMNLTIPILLIRGKLSDVVSSEGVQDFLD
MUL_0147|M.ulcerans_Agy99           RA-------------------AMNLTIPILLIRGKLSDVVTSEGVQDFLD
MAV_1254|M.avium_104                QA-------------------AKNLSIPVLLIRGKLSDVVSPEGVRHFLA
Mflv_2096|M.gilvum_PYR-GCK          QA-------------------ATELTVPILLIRGKLSDVVSEEAVQDFLA
Mvan_4609|M.vanbaalenii_PYR-1       QA-------------------AIELTIPILLIRGKLSDVVSEEAVQDFLT
MSMEG_5209|M.smegmatis_MC2_155      QA-------------------AVNLTVPILLIRGKLSDVVSPEGVAEFLE
TH_2112|M.thermoresistible__bu      RA-------------------ALRLTVPILLVRGKLSDVVSAEGVEEFLA
MAB_2045|M.abscessus_ATCC_1997      MMSAFL------------LDGARQVSAPTLLVRGLLSDIVSEETVRHFLT
MLBr_02297|M.leprae_Br4923          YQRWAVRSQLRNEGRKFMKSMSRPFSVPLLHVRGDADPYLLADSVDRTRR
                                                         :  .: * * :**  .  :  : .     

Mb1154c|M.bovis_AF2122/97           KVPNAEFVELSNAGRTAAGDDNDAFTDVVVDFVRRLS-------------
Rv1123c|M.tuberculosis_H37Rv        KVPNAEFVELSNAGRTAAGDDNDAFTDVVVDFVRRLS-------------
MMAR_4337|M.marinum_M               KVPHAEFVELSNAGHTAAGDDNDAFTEVVVDFVKRRAATG----------
MUL_0147|M.ulcerans_Agy99           KVPHAEFVELSNAGHTAAGDDNDAFTEVVVDFVKRRAATG----------
MAV_1254|M.avium_104                TVPRAEFVELSNAGHTAAGDDNDAFSDAVVAFVKRR--------------
Mflv_2096|M.gilvum_PYR-GCK          KVPGAEFAELSGAGHTAAGDDNDAFSEVVTRFVLR---------------
Mvan_4609|M.vanbaalenii_PYR-1       KVPNAEFVELPGAGHTAAGDDNDAFSEVVAQFVLR---------------
MSMEG_5209|M.smegmatis_MC2_155      KVPAAEFVELSDAGHTAAGDDNDAFTQVVVEFVNR---------------
TH_2112|M.thermoresistible__bu      KVPSAEFVELSAAXXXATIPARGSPRRCVTSPVCRRRPPTSRPAPSPRSA
MAB_2045|M.abscessus_ATCC_1997      VVPHAQTVDVSGAGHMIAGDNNDAFSTAVVEFLDRTI-------------
MLBr_02297|M.leprae_Br4923          YAPHGRYVSVSDAGHFSHEEAPEEINRYLTRFLKQVHGPRLS--------
                                     .* .. ..:. *               :.  : :               

Mb1154c|M.bovis_AF2122/97           ----------------
Rv1123c|M.tuberculosis_H37Rv        ----------------
MMAR_4337|M.marinum_M               ----------------
MUL_0147|M.ulcerans_Agy99           ----------------
MAV_1254|M.avium_104                ----------------
Mflv_2096|M.gilvum_PYR-GCK          ----------------
Mvan_4609|M.vanbaalenii_PYR-1       ----------------
MSMEG_5209|M.smegmatis_MC2_155      ----------------
TH_2112|M.thermoresistible__bu      PRHGNVAGPGANAVRR
MAB_2045|M.abscessus_ATCC_1997      ----------------
MLBr_02297|M.leprae_Br4923          ----------------