For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PDTVGPQPQYETFADEFLDHARDGFYNAHYDRPACLALIGDVAGRTILDAACGPGLYAEELAKRGASLIG FDQSPRMVELARARVPSGDFRVHDLAGPLDWLPSQSVDAVLLALALEYVDDRTAMLREFHRVLRPAGALV LSRMHPTGDWLRHGGNYFETRVVEETWSRGWNVRYWLAPLERTCSELRDAGFLIEELREPRPTEEAARRD PQAYQRLAQAPEGFMTIRAVPDFRLRRPAAGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3286 | - | - | 100% (243) | methyltransferase |
| M. smegmatis MC2 155 | MSMEG_6572 | - | 9e-14 | 34.67% (150) | methyltransferase |
| M. smegmatis MC2 155 | MSMEG_2350 | - | 3e-10 | 38.61% (101) | hypothetical protein MSMEG_2350 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3374 | - | 3e-09 | 35.14% (111) | methyltransferase (methylase) |
| M. gilvum PYR-GCK | Mflv_3090 | - | 2e-09 | 34.40% (125) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3342 | - | 3e-09 | 35.14% (111) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_02273 | ubiE | 5e-08 | 36.00% (100) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. abscessus ATCC 19977 | MAB_1977 | - | 6e-31 | 38.53% (218) | putative methyltransferase |
| M. marinum M | MMAR_3525 | - | 1e-09 | 29.15% (199) | methylase |
| M. avium 104 | MAV_2111 | - | 3e-10 | 31.98% (172) | methyltransferase, UbiE/COQ5 family protein |
| M. thermoresistible (build 8) | TH_2193 | - | 2e-10 | 39.60% (101) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1436 | - | 1e-09 | 36.04% (111) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2098 | - | 1e-11 | 39.62% (106) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3286|M.smegmatis_MC2_155 -----------MPDTVGPQPQ---YETFADEFLDHARDGFYNAHYDRPAC
MAB_1977|M.abscessus_ATCC_1997 --------MDPAEHARHTRDV---YDRLAPVWSATTDDGPFNGLLERPAL
Mb3374|M.bovis_AF2122/97 -------------MTCSRRDM---SLSFGSAVGAYERGRPS---YPPEAI
Rv3342|M.tuberculosis_H37Rv -------------MTCSRRDM---SLSFGSAVGAYERGRPS---YPPEAI
MUL_1436|M.ulcerans_Agy99 ------------MVSGSAQDP---SLSFGSAAAAYERGRPS---YPPEAI
TH_2193|M.thermoresistible__bu --------MSAFSTAGSDADGPISVLPLTGERTVPGLERENYWFRRHEVV
Mvan_2098|M.vanbaalenii_PYR-1 --------MSASVTDGPTEDP--APMALTGERTVPGVAEENYWFRRHEVV
Mflv_3090|M.gilvum_PYR-GCK ---------MSTRWQQSDRPR---GEDYDARWKRLAASGAS--VHGEADL
MAV_2111|M.avium_104 ---------MTAPQRRGLNDVVTRMWSFLAPAYDLPFLQQWVYRPPHNEV
MLBr_02273|M.leprae_Br4923 MPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYDLTNTVLSLGQDRYWRRA
MMAR_3525|M.marinum_M ------------MVTDYNQGE-------IAERYKKTKAIPVRTRIEAYSF
MSMEG_3286|M.smegmatis_MC2_155 LALIG-DVAGRTILDAACGPGLYAEELAKRG--ASLIGFDQSPRMVELAR
MAB_1977|M.abscessus_ATCC_1997 RSLIPRPLAGRSVLDAGCGSGAQCAWLLGEG--ADVTGLDLSPAMVDQAR
Mb3374|M.bovis_AF2122/97 DWLLP--AAARRVLDLGAGTGKLTTRLVERG--LDVVAVDPIPEMLDVLR
Rv3342|M.tuberculosis_H37Rv DWLLP--AAARRVLDLGAGTGKLTTRLVERG--LDVVAVDPIPEMLDVLR
MUL_1436|M.ulcerans_Agy99 DWLLP--AGARDVLDLGAGTGKLTTRLVERG--LDVVAVDPIPEMLEVLR
TH_2193|M.thermoresistible__bu YQRLAHRCAGRVVLEAGCGEGYGADLLAEVA--AHVIGLDYDAATVAHVR
Mvan_2098|M.vanbaalenii_PYR-1 YRRLVDRCAGRDVLEAGCGEGYGAALIAEVA--RSVIGLDYDESAVAHVR
Mflv_3090|M.gilvum_PYR-GCK IEALLREGGGTRVLDAGCGTGRVAIELAARG--FDVVGLDADPTMLETAR
MAV_2111|M.avium_104 IAQLR-NHGSRRIADIACGTGILSERIQRELNPDEIYGVDMSDGMLNQAR
MLBr_02273|M.leprae_Br4923 TRSALRIGPGQKVLDLAAGTAVSTAELSKSG--AWCVAADFSVRMLATGG
MMAR_3525|M.marinum_M LKHIG-DVTGEKVVDIACGAGDYARVMRRAG-AARVVGFDISEKMIGLAR
. : : ..* . : . * :
MSMEG_3286|M.smegmatis_MC2_155 ARVP-SGDFRVHDLAGPLDWLPSQSVDAVLLALALEYVDDR---TAMLRE
MAB_1977|M.abscessus_ATCC_1997 QRCGSAAKLMVADLADDLPLEP-RSFDGVTCSLALHYLRDW---QVPLAS
Mb3374|M.bovis_AF2122/97 AALP--QTVALLGTAEEIPLDD-NSVDAVLVAQAWHWVDP----ARAIPE
Rv3342|M.tuberculosis_H37Rv AALP--QTVALLGTAEEIPLDD-NSVDAVLVAQAWHWVDP----ARAIPE
MUL_1436|M.ulcerans_Agy99 ASLP--RTLALLGTAEEIPLED-NSVDAVLVAQAWHWVDP----ARAIPE
TH_2193|M.thermoresistible__bu ARYP--RVDIRHGNLVDLPLAD-ASVDVVVNFQVIEHLWDQ---EKFIAE
Mvan_2098|M.vanbaalenii_PYR-1 ARYP--RVDMRHGNLAALPLPT-ASVDVVVNFQVIEHLWDQ---GQFVAE
Mflv_3090|M.gilvum_PYR-GCK AKAP--RLRWIEADLVDTDDHLDETFDVVALPGNVMIFLDRGTEAAVVAA
MAV_2111|M.avium_104 AKSD--RVQWLRAPAEQLPFDD-GALDAVVTTSAFHFFDQP----AALRE
MLBr_02273|M.leprae_Br4923 ARKVP----KVAADATQLPFSD-GVFDAVTISFGLRNIADY---QAALRE
MMAR_3525|M.marinum_M EQEAHEPLGIEYFVADASQEVAQQDYDLAISAYLLVYARDRDELARMCRG
* .
MSMEG_3286|M.smegmatis_MC2_155 FHRVLRPAGALVLSRMHP---------TGDWLR-HGGNYFETRVVEETWS
MAB_1977|M.abscessus_ATCC_1997 FARILRPGGWVVISLDHP---------FGAPLPDQRGGYFQHQLVSDTWN
Mb3374|M.bovis_AF2122/97 VARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRVTLPEPFT
Rv3342|M.tuberculosis_H37Rv VARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRVTLPEPFT
MUL_1436|M.ulcerans_Agy99 VARVLRPGGRLGLVWNTRDERLGWVRELGRIIGRDSDPVRDKVTLPEPFT
TH_2193|M.thermoresistible__bu CLRVLRPGGQLLVSTPNR---ITFTPGSDTPVNPFHTRELNAAELTELLT
Mvan_2098|M.vanbaalenii_PYR-1 CARVLRPGGVLLMSTPNR---ITFSPGRDTPVNPFHTRELNAAELTELIE
Mflv_3090|M.gilvum_PYR-GCK LARRLAPGGLLVAGFQLG--------------------------------
MAV_2111|M.avium_104 FHRVLAPGGLVAVSALST--------------------------RRPLLQ
MLBr_02273|M.leprae_Br4923 MARVTRPGGQLVVCEFST--------------------------PTNALV
MMAR_3525|M.marinum_M VACRVRPGGRFVTLTTNP-------------------GLYTFGRVPDYRK
*.* .
MSMEG_3286|M.smegmatis_MC2_155 RG---WNVRYWLAPLERTCSELRDAGFLIEELREPRP-TEEAARRDPQAY
MAB_1977|M.abscessus_ATCC_1997 KADVEVTQHFWRRPLGQVADAFADAGLLIERISEPRP-SAEAIRRFPAEL
Mb3374|M.bovis_AF2122/97 TVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATH
Rv3342|M.tuberculosis_H37Rv TVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATH
MUL_1436|M.ulcerans_Agy99 GVARHHVEWTNYLTPQALIDLVASRSYCITSPAEVRTKTLDQVRELLATH
TH_2193|M.thermoresistible__bu DGGFGLSAMYGVFHGPRLAELDARHGGSIIDAQISRALADEPWPAELLAD
Mvan_2098|M.vanbaalenii_PYR-1 SADFAMEAMLGVFHGRRLAEIDARHGGSVIDAQIARALADAPWPAELLAD
Mflv_3090|M.gilvum_PYR-GCK ---------TGRLTLDRYDEITATAALELVDRWATWDRQPYDGGDYAVSL
MAV_2111|M.avium_104 ASADSRWKPQHNASAPEMRKLFEDAGFVIGDQYRIPRPAWTRLVSDLLTV
MLBr_02273|M.leprae_Br4923 ANVYTEYLMRALPQVARLVSSNPDAYIYLAESIRAWPDQVTLACQLSRTG
MMAR_3525|M.marinum_M YGFQIKLADAAFEGAPIELTAFVDGAPLVIENYYLPIAAYEAALRQAGFH
:
MSMEG_3286|M.smegmatis_MC2_155 QRLAQAPEGFMT-----------IRAVPDFRLRRPAAGR-
MAB_1977|M.abscessus_ATCC_1997 RNVVDSPS------------------FIVYRLRYWGAPA-
Mb3374|M.bovis_AF2122/97 PALANSNG----------------LALPYVTVCVRATLA-
Rv3342|M.tuberculosis_H37Rv PALANSNG----------------LALPYVTVCVRATLA-
MUL_1436|M.ulcerans_Agy99 PALANSAG----------------LALPYVTVCVSATLAA
TH_2193|M.thermoresistible__bu VASVRTEDFDLIRCDEDDRDRDGHNIDDSLDLVAIAVRP-
Mvan_2098|M.vanbaalenii_PYR-1 IESVTIEDFDLVPADGTHRD-----IDDSLDLVAIAVRT-
Mflv_3090|M.gilvum_PYR-GCK HRLT------------------------------------
MAV_2111|M.avium_104 GTKRD-----------------------------------
MLBr_02273|M.leprae_Br4923 WASPRWRN----------------LTGGIVALHAADKPVR
MMAR_3525|M.marinum_M DFVVHVPELAAAPQGEDEGDFWDDYLNYPPAIVIECVRD-