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MDSQVHKLTVKGRATRDRIVEGAAAEIRERGVAATTLDDIRARTQTSKSQLFHYFPDGKDQLLLAVAEHE AHMVLEDQQPHLGELTSWAAWRRWRDAVVDRYRRQGQHCPLAVLMSEIGRTTPGAEAVSAALVTKWHGEI ATGIRDMQAQGKIADRVDADRTAAALLAGIQGGVGIMLSTGDLGFLEAALDVGIAALRD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4594 | - | - | 100% (199) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3009 | - | 8e-11 | 26.77% (198) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0275 | - | 6e-09 | 25.61% (164) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0202 | - | 3e-11 | 32.72% (162) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3287 | - | 3e-11 | 29.51% (183) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0196 | - | 3e-11 | 32.72% (162) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1881c | - | 7e-26 | 35.42% (192) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2960 | - | 2e-09 | 27.27% (165) | transcriptional regulatory protein |
| M. avium 104 | MAV_4985 | - | 9e-11 | 28.14% (199) | regulatory protein, TetR |
| M. smegmatis MC2 155 | MSMEG_5206 | - | 2e-83 | 75.76% (198) | regulatory protein |
| M. thermoresistible (build 8) | TH_3160 | - | 6e-08 | 24.34% (189) | PUTATIVE putative regulatory protein, TetR |
| M. ulcerans Agy99 | MUL_1119 | - | 4e-08 | 24.86% (181) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0202|M.bovis_AF2122/97 ------------MQGP----------RERMVVSAALLIRERGAHATAISD
Rv0196|M.tuberculosis_H37Rv ------------MQGP----------RERMVVSAALLIRERGAHATAISD
MAV_4985|M.avium_104 ------------MRSP----------REKMVVSAALLIRERGAHATAISD
Mflv_3287|M.gilvum_PYR-GCK ------------MTTP----------RERMVVSAALLIRERGAHPTAIAD
MUL_1119|M.ulcerans_Agy99 ------------MTPPSTSTPKRGGTREKMLISAAQVMRERGAAGVTIDS
TH_3160|M.thermoresistible__bu -MGVEVTRRRDPQSGP----------RAAMLRSAVALMRRQGVAATSFAD
MMAR_2960|M.marinum_M ------------MAEDSG--------RQRMVAGAAEMISRRGLNATSVRE
Mvan_4594|M.vanbaalenii_PYR-1 -----------MDSQVHKLTVKGRATRDRIVEGAAAEIRERGVAATTLDD
MSMEG_5206|M.smegmatis_MC2_155 -----------MDQQVQKLTPKGAATRRRIIEGAAAEIHSRGVADTTLDD
MAB_1881c|M.abscessus_ATCC_199 MLSGMVGKSSPPSAAKLPATAHGRRTRAAIIDAAAQMMYQKGVAATSLDD
* :: .*. : :* .:. .
Mb0202|M.bovis_AF2122/97 VLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVAAMINEAEGG----L
Rv0196|M.tuberculosis_H37Rv VLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVAAMINEAEGG----L
MAV_4985|M.avium_104 VLEHSGAPRGSAYHYFPGGRTQLLCEAVDFAGEYVAAVIAGAESG----A
Mflv_3287|M.gilvum_PYR-GCK VLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAAEFMAERLSRASSS----L
MUL_1119|M.ulcerans_Agy99 VLARSGAPRGSVYYHFPDGRNQILIEALRYAGDSITAVIDKAADKGA--R
TH_3160|M.thermoresistible__bu VLADSGAPRGSIYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAADLP
MMAR_2960|M.marinum_M LAKHTQAPLGSTYHYFPGGKYDLATEAVRWADDLTVGVLARELAAGP--Q
Mvan_4594|M.vanbaalenii_PYR-1 IRARTQTSKSQLFHYFPDGKDQLLLAVAEHEAHMVLEDQQPHLGELTS-W
MSMEG_5206|M.smegmatis_MC2_155 IRARTGTSKSQLFHYFPGGKDQLMLAVAEHEAQQVLADQQPYLGDLTS-W
MAB_1881c|M.abscessus_ATCC_199 ILAASSTGKSQLYHYFKD-RSELVKAVVERQTELVLAAQ-PTLTQIDS-M
: : : .. :::* : :: .
Mb0202|M.bovis_AF2122/97 ELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAA
Rv0196|M.tuberculosis_H37Rv ELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAA
MAV_4985|M.avium_104 RLLDTLIDTYREQLRDSDFRAGCPVVAVAVEAGEQSDAER--PVIERAAA
Mflv_3287|M.gilvum_PYR-GCK RVLDDLFGYYRTQLQDSDFRAGCPVVAVAVESGDPDKPEQSAPVIERAAA
MUL_1119|M.ulcerans_Agy99 ALLREFVRLWEHLLTDGGFAAGCPVVAAALGPADDE-----VELAAEAGT
TH_3160|M.thermoresistible__bu TALRELVGVWRDGLEAGDYAVGCPIVAAALGTERAAR--------DVAGV
MMAR_2960|M.marinum_M AGLSAFLAMWRKIVIDSNFHAGCPVLAVSVEDLPEEHHAP----RRAAAT
Mvan_4594|M.vanbaalenii_PYR-1 AAWRRWRDAVVDRYRRQGQ--HCPLAVLMSEIGRTTPGAE-----AVSAA
MSMEG_5206|M.smegmatis_MC2_155 TSWQRWRDAVVDRYRRQGQ--HCPLSTLMSELGRSTPGAQ-----AVSRA
MAB_1881c|M.abscessus_ATCC_199 DGVEQWAQAILANHDVPGGPFGCPLGSMAAELK-NDPAYQ-----PALAA
. **: .
Mb0202|M.bovis_AF2122/97 VFDRWSDLTAQRFIADG-----IPPDRAHELAVLATSTLEGAILLARVRR
Rv0196|M.tuberculosis_H37Rv VFDRWSDLTAQRFIADG-----IPPDRAHELAVLATSTLEGAILLARVRR
MAV_4985|M.avium_104 AFDRWTDLIAQRFIADG-----IRRRRAAELAVLATSALEGAIVLARARR
Mflv_3287|M.gilvum_PYR-GCK ALTRWSDIIEQRLIADG-----VPRADAAALAMLVLTSFEGAIVVARATR
MUL_1119|M.ulcerans_Agy99 ILDSWCAALGRAFVADG-----FDESTAASLAVTSIAALEGAIMLCRSTR
TH_3160|M.thermoresistible__bu AFADLTGLISDKLVSDG-----MARRRANSVAVLILTAMEGALVLAQARR
MMAR_2960|M.marinum_M AFQRWTSMLADSLRDAG-----AAEQDAQQVATLIVASVEGTVAMCRAQQ
Mvan_4594|M.vanbaalenii_PYR-1 LVTKWHGEIATGIRDMQAQGKIADRVDADRTAAALLAGIQGGVGIMLSTG
MSMEG_5206|M.smegmatis_MC2_155 LLRQWHDEITTGIRHMQGHGEITADLDAERMAAALLAGIQGGVNVMLVTG
MAB_1881c|M.abscessus_ATCC_199 AFGQWQSLLADGLIRMQDRGHLDPHEDPQRLAAAVLATLQGGMLMGRATM
. : . * : .:* : :
Mb0202|M.bovis_AF2122/97 DLTPLDLVHRQLRNLLLAELP------ERSR----
Rv0196|M.tuberculosis_H37Rv DLTPLDLVHRQLRNLLLAELP------ERSR----
MAV_4985|M.avium_104 DPAPLDVVHRQLRDLLAAELAGETAAGRKSRHDR-
Mflv_3287|M.gilvum_PYR-GCK DLKPLDLVAGQLASLIDARTV------TRRK----
MUL_1119|M.ulcerans_Agy99 SVEPLRQVGEQLEFLVKARGF-----VAQSRLDSE
TH_3160|M.thermoresistible__bu DPAALDAVVDELTLLCSGSAD--------------
MMAR_2960|M.marinum_M SIAPLDLVTAQLGRAIDAVLPGATSPDAHS-----
Mvan_4594|M.vanbaalenii_PYR-1 DLGFLEAALDVGIAALRD-----------------
MSMEG_5206|M.smegmatis_MC2_155 DLTYLEAALDSGIAALQRG----------------
MAB_1881c|M.abscessus_ATCC_199 DITVLRDSLEMALDSIRRALRD-------------
. *