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MATATRERFLTAATGLFRRQGYSGTGLKQIVAESRAPLGSLYHFFPGGKQDLAVQAIAHTAERYRELLDR VFAKSTDIGQATVTWFNWAARALQETDYADGCPIGTVACEVASSNEALRQATQAVLASWQSRVAAELIGA GVPTAQARRLATFAVASLEGAILLARAHRSTRPLRETGRVVADTLRAATDRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0149 | - | - | 100% (192) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4985 | - | 6e-22 | 31.89% (185) | regulatory protein, TetR |
| M. avium 104 | MAV_4948 | - | 3e-19 | 28.34% (187) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0202 | - | 4e-22 | 32.09% (187) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3237 | - | 2e-31 | 42.16% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0196 | - | 4e-22 | 32.09% (187) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2447c | - | 9e-37 | 44.44% (189) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0436 | - | 4e-22 | 30.73% (192) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_6764 | - | 2e-33 | 42.62% (183) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3160 | - | 7e-19 | 31.36% (169) | PUTATIVE putative regulatory protein, TetR |
| M. ulcerans Agy99 | MUL_2793 | - | 8e-21 | 36.36% (187) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5860 | - | 3e-32 | 42.16% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0202|M.bovis_AF2122/97 -----------MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
Rv0196|M.tuberculosis_H37Rv -----------MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
MMAR_0436|M.marinum_M -----------MPSPRERMVISAVLLIRERGARATAISDVLQHSGAPRGS
TH_3160|M.thermoresistible__bu MGVEVTRRRDPQSGPRAAMLRSAVALMRRQGVAATSFADVLADSGAPRGS
MUL_2793|M.ulcerans_Agy99 ------------MTARERLIESAIELLRRNGVAGTGLADLLEHSGTARRS
MSMEG_6764|M.smegmatis_MC2_155 ---------MAELGTRERILQATAELYRRQGMSATGLKQISGAAKAPFGS
Mvan_5860|M.vanbaalenii_PYR-1 ---------MADPSTRSRILDATAELYRRQGMPATGLKQISAAAQAPFGS
Mflv_3237|M.gilvum_PYR-GCK ---------MTEPTTRDRILDAAAELYRRQGMSATGLKQISAAARAPFGS
MAB_2447c|M.abscessus_ATCC_199 ----------MPANTRDRIVAATCELFRRQGMTGTGLKQIAQSAGAPFGS
MAV_0149|M.avium_104 ----------MATATRERFLTAATGLFRRQGYSGTGLKQIVAESRAPLGS
.* :: :: * *..* .*.: :: : :. *
Mb0202|M.bovis_AF2122/97 AYHYFPGGRTQLLCEAVDYAG----EHVAAMINEAEG-GLELLDALIDKY
Rv0196|M.tuberculosis_H37Rv AYHYFPGGRTQLLCEAVDYAG----EHVAAMINEAEG-GLELLDALIDKY
MMAR_0436|M.marinum_M AYHYFPGGRTQLLCEAVDYAG----AHVAKIIGSANR-SLDLLDTLIDQY
TH_3160|M.thermoresistible__bu IYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAAD-LPTALRELVGVW
MUL_2793|M.ulcerans_Agy99 VYVNFPGGKSELMTEATRTAG---RLMDSTLASIAAG-GGQPLVAFADSW
MSMEG_6764|M.smegmatis_MC2_155 IYHHFPGGKEAISVEVIRSEGIRYGEFVGAQLADTDP--ATGIPQLFESA
Mvan_5860|M.vanbaalenii_PYR-1 IYHHFPGGKEAISVEVIRREGIRYAELVGAQLADTDP--LTGIPQLFEKA
Mflv_3237|M.gilvum_PYR-GCK IYHHFPGGKEAISAEVIRSEGIRYAAFVGAQLADINP--ANGIEAVFASA
MAB_2447c|M.abscessus_ATCC_199 IYHFFPGGKAQLADEAIRAAGAMYRDLVLAVFDQNGPDLAATIRTAFAAA
MAV_0149|M.avium_104 LYHFFPGGKQDLAVQAIAHTAERYRELLDRVFAKSTD-IGQATVTWFNWA
* **.*: : :. .
Mb0202|M.bovis_AF2122/97 RQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTA
Rv0196|M.tuberculosis_H37Rv RQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTA
MMAR_0436|M.marinum_M REQLRATDFRAGCPVAAVSVEAGEPSDRERMAPVVEHAAAVFDRWSDLIA
TH_3160|M.thermoresistible__bu RDGLEAGDYAVGCPIVAAALGT------ERAARDVA--GVAFADLTGLIS
MUL_2793|M.ulcerans_Agy99 KQTLRASDYAAGCPIVAAALGR------TESPSAADVAGEVFGAWQTVLA
MSMEG_6764|M.smegmatis_MC2_155 GRLLQSQDYSEACSIETIALEVAS-----TNEVLRQESATVFENWLTGLA
Mvan_5860|M.vanbaalenii_PYR-1 GRDLEAQDYSEACSIETIALEVAS-----TNERLRVEAAEVFQSWLTGLA
Mflv_3237|M.gilvum_PYR-GCK AELLESQDYSEACSIETIALEVAS-----TNERLRGEAAEVFETWLHQLA
MAB_2447c|M.abscessus_ATCC_199 ADNLIATDYTDACPIATIALEVAS-----TDEDLRHATAEVFTDWIEQGT
MAV_0149|M.avium_104 ARALQETDYADGCPIGTVACEVAS-----SNEALRQATQAVLASWQSRVA
* *: .*.: : : .: :
Mb0202|M.bovis_AF2122/97 QRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNL
Rv0196|M.tuberculosis_H37Rv QRFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNL
MMAR_0436|M.marinum_M QRFVSDGIPLDSAHELAVTAMSTLEGALLLARVRRDLTPLDVVHRQLRSM
TH_3160|M.thermoresistible__bu DKLVSDGMARRRANSVAVLILTAMEGALVLAQARRDPAALDAVVDELT-L
MUL_2793|M.ulcerans_Agy99 GRFRAQGVGDDTAESLATTVVAAVEGAVILCLAARSTDPLDRTVPMLQQL
MSMEG_6764|M.smegmatis_MC2_155 RWFGQLDVDEATSRRLAVITLTALEGAFVLCRTLRSVEPIIAAGQGVQAA
Mvan_5860|M.vanbaalenii_PYR-1 AWFGRLALTEPECRRLAMITLTALEGAFVLCRTLRSIDPIIAAGHGVQAA
Mflv_3237|M.gilvum_PYR-GCK GWFGQLDIGDEQSRRLATVMLTALEGAFVLCRTLRSVEPMLIAGHGVQAA
MAB_2447c|M.abscessus_ATCC_199 ERIADTGLPPGTRRRLILGFITGLEGAFVLSRALRDPEPLFAAGETVAAA
MAV_0149|M.avium_104 AELIGAGVPTAQARRLATFAVASLEGAILLARAHRSTRPLRETGRVVADT
: : . : : :***.:*. . *. .: . :
Mb0202|M.bovis_AF2122/97 LLAELPERSR----
Rv0196|M.tuberculosis_H37Rv LLAELPERSR----
MMAR_0436|M.marinum_M LLAQLPEGNRNDHN
TH_3160|M.thermoresistible__bu LCSGSAD-------
MUL_2793|M.ulcerans_Agy99 IAQHTSRPSG----
MSMEG_6764|M.smegmatis_MC2_155 VTATLAEKR-----
Mvan_5860|M.vanbaalenii_PYR-1 VRAAATTRRS----
Mflv_3237|M.gilvum_PYR-GCK VHAVLASAQ-----
MAB_2447c|M.abscessus_ATCC_199 ATSALAALATHAE-
MAV_0149|M.avium_104 LRAATDRG------