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VAARGQGCYLYDETDREYLDFTAGIGVVSTGHCHPRVVEAAQRQVATLIHGQYTTVMHRPLQNLVRRLGE VLPPSLNSLFFANSGSEAVEAAVRLARQATGRPNIIVFQGGFHGRTLAAATMTTSGPRFSSGIGPLMAGV YSAPFPTAYRYGWSEAEATRFALQELDYLFATATAPGQVAAMVIEPVLGEGGYIPANTEFLTGIAERARE HGILLVLDEVQTGFGRTGQYFGHQHFGVTPDVLVMAKGIASGFPISGIAASAELMGRAWPGSQGGTYGAN AVACAAALATLDVIDEEGLVDNARARGQELLDGARKIAADRGIDGDVRGLGLMVGVEFSQDGRPAPQRAA RAQAAAAENGLLLLMCGPHMNVVRMIPPLVVTADQISDALGIWSSVVAGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4417c | - | - | 100% (401) | aminotransferase |
| M. abscessus ATCC 19977 | MAB_4207 | - | 6e-67 | 36.21% (406) | 4-aminobutyrate aminotransferase |
| M. abscessus ATCC 19977 | MAB_0821 | - | 2e-66 | 35.93% (398) | 4-aminobutyrate aminotransferase GabT |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2620 | gabT | 1e-66 | 35.19% (412) | 4-aminobutyrate aminotransferase |
| M. gilvum PYR-GCK | Mflv_3818 | - | 3e-61 | 34.53% (417) | 4-aminobutyrate aminotransferase |
| M. tuberculosis H37Rv | Rv2589 | gabT | 1e-66 | 35.19% (412) | 4-aminobutyrate aminotransferase |
| M. leprae Br4923 | MLBr_00485 | gabT | 1e-65 | 33.09% (405) | 4-aminobutyrate aminotransferase |
| M. marinum M | MMAR_2118 | gabT | 2e-65 | 34.07% (408) | 4-aminobutyrate aminotransferase GabT |
| M. avium 104 | MAV_3470 | gabT | 3e-63 | 33.25% (412) | 4-aminobutyrate aminotransferase |
| M. smegmatis MC2 155 | MSMEG_2487 | - | 1e-152 | 65.92% (402) | 4-aminobutyrate aminotransferase |
| M. thermoresistible (build 8) | TH_3529 | - | 1e-56 | 35.88% (393) | PUTATIVE aminotransferase |
| M. ulcerans Agy99 | MUL_1723 | gabT | 6e-66 | 34.07% (408) | 4-aminobutyrate aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_1858 | - | 5e-70 | 38.04% (397) | 4-aminobutyrate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2118|M.marinum_M MAS-------LDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVV
MUL_1723|M.ulcerans_Agy99 MAS-------LDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVV
MAV_3470|M.avium_104 MAR-------LEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPVFVA
Mb2620|M.bovis_AF2122/97 MAS-------LQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVA
Rv2589|M.tuberculosis_H37Rv MAS-------LQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVA
MLBr_00485|M.leprae_Br4923 MTS-------VEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVT
Mflv_3818|M.gilvum_PYR-GCK MSA-------LEQSRHLATAIPGPRSVELASRKNTAVSRGVGTTMPVYAA
Mvan_1858|M.vanbaalenii_PYR-1 MTTSLVGGPALPQARRMVTDIPGPRSAELAARRSAALPAGLASAAGVYVA
MAB_4417c|M.abscessus_ATCC_199 ----------------------------------------------MVAA
MSMEG_2487|M.smegmatis_MC2_155 ---------------------------------MTELSQALKQATGVIAA
TH_3529|M.thermoresistible__bu --------------------VSGSKGRHTLLDRWQGVMMNNYGTPPLALV
: .
MMAR_2118|M.marinum_M RAGGGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCF
MUL_1723|M.ulcerans_Agy99 RAGGGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCF
MAV_3470|M.avium_104 RAGGGIVEDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTHTCF
Mb2620|M.bovis_AF2122/97 RAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCF
Rv2589|M.tuberculosis_H37Rv RAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCF
MLBr_00485|M.leprae_Br4923 RAAGGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCF
Mflv_3818|M.gilvum_PYR-GCK RAFGGIVEDVDGNRLIDLGSGIAVTTVGNASPRVVAAVAEQAAEFTHTCF
Mvan_1858|M.vanbaalenii_PYR-1 AAGGGVAVDVDGNSFIDLGSGIAVTTVGNSAPAVVERATAQLARYTHTCF
MAB_4417c|M.abscessus_ATCC_199 RGQGCYLYDETDREYLDFTAGIGVVSTGHCHPRVVEAAQRQVATLIHGQY
MSMEG_2487|M.smegmatis_MC2_155 RGEGVLLYDEQDRRYLDFTAGIGVTSTGHCHPRVVEAAQRQVGTLIHGQY
TH_3529|M.thermoresistible__bu SGDGAVVTDADGKSYLDLLGGIAVNILGHRHPAVIEAVTRQLNTLGHTSN
. * * .. :*: .**.* *: * *: . * *
MMAR_2118|M.marinum_M MVTPYEQYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHTRK
MUL_1723|M.ulcerans_Agy99 MVIPYEHYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHTRK
MAV_3470|M.avium_104 MVTPYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAYTRK
Mb2620|M.bovis_AF2122/97 MVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGK
Rv2589|M.tuberculosis_H37Rv MVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGK
MLBr_00485|M.leprae_Br4923 IITPYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIKVARSYTRK
Mflv_3818|M.gilvum_PYR-GCK MVTPYEGYVAVAEALNRLTPGDGDKRSALFNSGSEAVENAVKIARTFTRK
Mvan_1858|M.vanbaalenii_PYR-1 LATPYEPYIEVAETLNRLTPGSHDKRTALFNTGSEAVENAVKYARAATGR
MAB_4417c|M.abscessus_ATCC_199 TTVMHRPLQNLVRRLGEVLPPS-LNSLFFANSGSEAVEAAVRLARQATGR
MSMEG_2487|M.smegmatis_MC2_155 TTVMHRPLLTLVERLGEVLPAG-LDRMFFANSGSEAIEAALRLSRQATGR
TH_3529|M.thermoresistible__bu LYATEPGVALAEALVGHLGAP---ARVFFCNSGAEANEVAFKIS-RLTGR
:..: . : *:*:** * :.: : * :
MMAR_2118|M.marinum_M QAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPYRDN
MUL_1723|M.ulcerans_Agy99 QAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPYRDN
MAV_3470|M.avium_104 PAVVAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPYRDG
Mb2620|M.bovis_AF2122/97 PAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDG
Rv2589|M.tuberculosis_H37Rv PAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDG
MLBr_00485|M.leprae_Br4923 PAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDG
Mflv_3818|M.gilvum_PYR-GCK QAVVSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPMSYPFRDA
Mvan_1858|M.vanbaalenii_PYR-1 SAVVVFDHAFHGRSLLTMTMTAKNQPYKHGFGPFAPEVYRAPMAYPYRWP
MAB_4417c|M.abscessus_ATCC_199 PNIIVFQGGFHGRTLAAATMTTSGPRFSSGIGPLMAGVYSAPFPTAYRYG
MSMEG_2487|M.smegmatis_MC2_155 PNVIVFHGGFHGRTVAAASMTTSGTKFRSGFSPLMAGVHVSPFPDPTHFG
TH_3529|M.thermoresistible__bu TKVVAAEGGFHGRTMGALALTGQPSKREP-FEPLPGDVIHVPYGDAGALE
:: . .:***: : ::* . : *: : * .
MMAR_2118|M.marinum_M LLD-KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVPAD
MUL_1723|M.ulcerans_Agy99 LLD-KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVPAD
MAV_3470|M.avium_104 LLD-KELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIVPAE
Mb2620|M.bovis_AF2122/97 LLD-KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAE
Rv2589|M.tuberculosis_H37Rv LLD-KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAE
MLBr_00485|M.leprae_Br4923 LLN-KDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIVPAE
Mflv_3818|M.gilvum_PYR-GCK EFGGKELATDGELAARRAITVIDKQVGAGNLAAVIIEPIQGEGGFIVPAE
Mvan_1858|M.vanbaalenii_PYR-1 SGP----QHCAEEAFAHFAQLVDAQIGADAVACVVVEPIQGEGGFIVPAD
MAB_4417c|M.abscessus_ATCC_199 WSE----AEATRFALQELDYLFATATAPGQVAAMVIEPVLGEGGYIPANT
MSMEG_2487|M.smegmatis_MC2_155 WPV----EQTTDFALSQLDYVLQTVSAPADTAAFFVEPVLGEGGYVPANE
TH_3529|M.thermoresistible__bu RAV----DDTT--------------------AAVFLEPIMGEGGVVVPPA
*...:**: **** : .
MMAR_2118|M.marinum_M GFLPALQRWCRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLIVT
MUL_1723|M.ulcerans_Agy99 GFLPALQRWSRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLIVT
MAV_3470|M.avium_104 GFLPTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDLICT
Mb2620|M.bovis_AF2122/97 GFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICT
Rv2589|M.tuberculosis_H37Rv GFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICT
MLBr_00485|M.leprae_Br4923 GFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDG---IVPDLICT
Mflv_3818|M.gilvum_PYR-GCK GFLPTLLDWCRANDVVFIADEVQTGFARTGAMFACEHEGPDGLVPDLIVT
Mvan_1858|M.vanbaalenii_PYR-1 GFLRAVAEFCRERGILLVADEVQTGIARTGAWFACEHDG---IVPDLITT
MAB_4417c|M.abscessus_ATCC_199 EFLTGIAERAREHGILLVLDEVQTGFGRTGQYFGHQHFG---VTPDVLVM
MSMEG_2487|M.smegmatis_MC2_155 RFLAGLRERADAHGILLVLDEVQTGYGRTGKFWGGEHFD---AKPDILVT
TH_3529|M.thermoresistible__bu GYLAAAREVTARHGALLVLDEVQTGIGRTGTFFAHQHDG---ITPDVVTL
:* . ::: ****** .*:* :. :* . **::
MMAR_2118|M.marinum_M AKGIADGFPLSAVTGRAEIMDAPHTSGLGGTFGGNPVACAAALATIETIE
MUL_1723|M.ulcerans_Agy99 AKGIADGFPLSAVTGRAEIMDAPHTSGLGGTFGGNPVACAAALATIETIE
MAV_3470|M.avium_104 AKAIADGLPLSAVTGRAQIMDAPHVGGLGGTFGGNPLACAAALATIETIE
Mb2620|M.bovis_AF2122/97 AKGIADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIE
Rv2589|M.tuberculosis_H37Rv AKGIADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIE
MLBr_00485|M.leprae_Br4923 AKGIADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATITTIE
Mflv_3818|M.gilvum_PYR-GCK AKGIAGGMPLSAVTGRADIMDAPHVSGLGGTYGGNPVACAAALATIETIE
Mvan_1858|M.vanbaalenii_PYR-1 AKGLAGGLPLAAVTGRADVMDAAHPGGIGGTYSGNPVACAAALGVFEEIE
MAB_4417c|M.abscessus_ATCC_199 AKGIASGFPISGIAASAELMGRAWPGSQGGTYGANAVACAAALATLDVID
MSMEG_2487|M.smegmatis_MC2_155 AKGLASGFPLSGIAASSELMAKAWPGSQGGTYGANAVACAAAIATLDVIA
TH_3529|M.thermoresistible__bu AKGLGGGLPIGACLAVGPAGDLLTPGMHGSTFGGNPVCTAAAVAVLGALA
**.:..*:*:.. . . . *.*:..*.:. ***:..: :
MMAR_2118|M.marinum_M RDGMVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAMELVKSGTAE
MUL_1723|M.ulcerans_Agy99 RDGMVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAMELVKSGTAE
MAV_3470|M.avium_104 SDGLIERARQLERLITEPLLRLQARDDRIGDVRGRGAMIAIELVKSGTAE
Mb2620|M.bovis_AF2122/97 SDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTE
Rv2589|M.tuberculosis_H37Rv SDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTE
MLBr_00485|M.leprae_Br4923 NDGLIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVELVKSGTAE
Mflv_3818|M.gilvum_PYR-GCK SDNLVARAAQIEALMKDRLGRMQAEDDRIGDVRGRGAMIAVELVKSGTLE
Mvan_1858|M.vanbaalenii_PYR-1 SGRLVERARTIGEAMVTALEDIAAGTDVIGEIRGRGAMIAAELVVPGTRE
MAB_4417c|M.abscessus_ATCC_199 EEGLVDNARARGQELLDGARKIAADRGIDGDVRGLGLMVGVEFS--QDGR
MSMEG_2487|M.smegmatis_MC2_155 DENLVANAAERGAQLKQALQTVADKHEQITDVRGLGLMIGNEFRD-ADGK
TH_3529|M.thermoresistible__bu EGDLINRADVLGKKLSHGIEELR--HPLVDHVRGRGLLCGVVLN------
:: .* : : .:** * : . :
MMAR_2118|M.marinum_M PDAALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPLTISDELLSEGLDIL
MUL_1723|M.ulcerans_Agy99 PDAALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPLTISDELLSEGLDIL
MAV_3470|M.avium_104 PDKDLTQRLSVAAHAAGVIVLTCGMFGNIIRLLPPLTISDELLAEGIDIL
Mb2620|M.bovis_AF2122/97 PDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIV
Rv2589|M.tuberculosis_H37Rv PDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIV
MLBr_00485|M.leprae_Br4923 PDPELTEKVATAAHATGVIILTCGMFGNIIRLLPPLTISDELLAEGLDIL
Mflv_3818|M.gilvum_PYR-GCK PDPELTRKLLTAAHAAGVIVLSCGTFGNVLRFLPPLAISDDLLLEGLDIL
Mvan_1858|M.vanbaalenii_PYR-1 PNRDAVAAISRHCHLNGVLTLTAGTFGNVMRFLPPLSISDELLTEAFDVV
MAB_4417c|M.abscessus_ATCC_199 PAPQRAARAQAAAAENGLLLLMCGPHMNVVRMIPPLVVTADQISDALGIW
MSMEG_2487|M.smegmatis_MC2_155 PDGTTAAAVQQEAARRGLLLLTCGAWGQVVRFIPALVVSADEVEEAAGIW
TH_3529|M.thermoresistible__bu ----APQAKAAEAAARDAGFLVNAAAPEVIRLAPPLIITETQIDEFLAAL
. . * . :::*: *.* : : :
MMAR_2118|M.marinum_M CQILADL----
MUL_1723|M.ulcerans_Agy99 CQILADL----
MAV_3470|M.avium_104 GGLLADL----
Mb2620|M.bovis_AF2122/97 CAILADL----
Rv2589|M.tuberculosis_H37Rv CAILADL----
MLBr_00485|M.leprae_Br4923 SRILGDF----
Mflv_3818|M.gilvum_PYR-GCK ELILRDL----
Mvan_1858|M.vanbaalenii_PYR-1 RDGFASL----
MAB_4417c|M.abscessus_ATCC_199 SSVVAGL----
MSMEG_2487|M.smegmatis_MC2_155 ADAVSAVVS--
TH_3529|M.thermoresistible__bu PGVLDTAKEAS
.