For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSTVLAGLRLPVVGAPMAGGITVPALARGVSAAGGFGLLPAGYRTITQLEQDREAMGELPFGFNVFVPTP DQGADLREYLDKLKVWADKLEVAPGDPVWHDDAYADKIEYLVANPVPVVSFTFGVPTAPDAHRLREAGSE VWITVTSAAEAKIAEGIGADALVVQGPEAGGHRSSFDAGAPDEPLLDLIASVRSVTALPVVAAGGIMDGA DIARVLAAGAAAAQLGTALVVTDESGAKQVYKDALLQPADTVVTRVFSGRPARSISNAFQRDMEAVAPVS FPALNSATKELRASGDPDVMSLWAGTEHHRARALPVAELMATLATELSAAQG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1641 | - | - | 100% (332) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0603c | - | 7e-20 | 28.48% (302) | 2-nitropropane dioxygenase |
| M. abscessus ATCC 19977 | MAB_0354c | - | 1e-18 | 27.14% (269) | 2-nitropropane dioxygenase family oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2804c | - | 3e-62 | 42.65% (340) | alanine rich oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2277 | - | 9e-67 | 46.69% (332) | 2-nitropropane dioxygenase, NPD |
| M. tuberculosis H37Rv | Rv2781c | - | 3e-62 | 42.65% (340) | alanine rich oxidoreductase |
| M. leprae Br4923 | MLBr_00387 | guaB2 | 1e-05 | 35.35% (99) | inosine 5'-monophosphate dehydrogenase |
| M. marinum M | MMAR_1927 | - | 2e-61 | 42.22% (334) | hypothetical protein MMAR_1927 |
| M. avium 104 | MAV_2990 | - | 1e-59 | 40.42% (334) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4971 | - | 2e-65 | 45.18% (332) | oxidoreductase |
| M. thermoresistible (build 8) | TH_1758 | - | 2e-22 | 27.60% (337) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_2153 | - | 6e-61 | 42.30% (331) | hypothetical protein MUL_2153 |
| M. vanbaalenii PYR-1 | Mvan_4389 | - | 6e-62 | 42.86% (329) | 2-nitropropane dioxygenase, NPD |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2804c|M.bovis_AF2122/97 --------------------------------------------------
Rv2781c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1927|M.marinum_M --------------------------------------------------
MUL_2153|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2277|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4389|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4971|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2990|M.avium_104 --------------------------------------------------
MAB_1641|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1758|M.thermoresistible__bu --------------------------------------------------
MLBr_00387|M.leprae_Br4923 MIRGMSNLKESSDFVASSYVRLGGLMDDPAATGGDNPHKVAMLGLTFDDV
Mb2804c|M.bovis_AF2122/97 ----------------MV--LGFWDIAVPIVGAPMAGGPSTPALAAAVSN
Rv2781c|M.tuberculosis_H37Rv ----------------MV--LGFWDIAVPIVGAPMAGGPSTPALAAAVSN
MMAR_1927|M.marinum_M ----------------MV--LGFWDIAVPIVGAPMAGGPGTPALAAAVSN
MUL_2153|M.ulcerans_Agy99 ----------------MV--LGFWDIAVPIVGAPMAGGPGTPALAAAVSN
Mflv_2277|M.gilvum_PYR-GCK ----------------MP--FDLRELTVPVLVAPMAGGPSTPELAAAGSA
Mvan_4389|M.vanbaalenii_PYR-1 ----------------MS--FDVRDLSVPVLVAPMAGGPSTPELAAAGTN
MSMEG_4971|M.smegmatis_MC2_155 ----------------MMGDFDLRGLTRPVIVAPMAGGPSTPALAAAGSN
MAV_2990|M.avium_104 -------------------MLAQFGMSIPLVAAPMSGGPTTPAMVSAAAR
MAB_1641|M.abscessus_ATCC_1997 ----------------MS--TVLAGLRLPVVGAPMAGGITVPALARGVSA
TH_1758|M.thermoresistible__bu ------------LSRIRTPLTDLVGIEHPVVQTGMG-WVAGARLVAATAN
MLBr_00387|M.leprae_Br4923 LLLPAASDVVPATADISSQLTKKIRLKVPLVSSAMD-TVTEARMAIAMAR
: *:: : * . :. . :
Mb2804c|M.bovis_AF2122/97 AGGLGFVAGGYLSADRLADDIAAARAATTGPIGANLFVPQPSVADW----
Rv2781c|M.tuberculosis_H37Rv AGGLGFVAGGYLSADRLADDIAAARAATTGPIGANLFVPQPSVADW----
MMAR_1927|M.marinum_M AGGLGFVAGGYRTADQFADDISAARAATTGPIGANIFVPQPSVADW----
MUL_2153|M.ulcerans_Agy99 AGGLGFVAGGYRTADQFADDISAARAATTGPIGANIFVPQPSVADW----
Mflv_2277|M.gilvum_PYR-GCK AGGLGFVAAGYLTADMFAEKLSAAMTLTREPVGANLFVPQPSAAMP----
Mvan_4389|M.vanbaalenii_PYR-1 AGGLGFVAAGYLTADVFAERVRAAQRLTSGPLGVNLFVPQPSAGTP----
MSMEG_4971|M.smegmatis_MC2_155 AGGLGFIAAGYLTADALAERIKATRELTSEPIGVNLFAPQPSAGTP----
MAV_2990|M.avium_104 AGALGILAAGYKTVQGIEAEIKAVRAES-IPFGVNLFAPNPVPVDP----
MAB_1641|M.abscessus_ATCC_1997 AGGFGLLPAGYRTITQLEQDR---EAMGELPFGFNVFVPTPDQG------
TH_1758|M.thermoresistible__bu AGGLGILASATMTLDELQTAVDKVKAATDKPFGINIRA------------
MLBr_00387|M.leprae_Br4923 AGGMGVLHRNLPVGEQAGQVETVKRSEAGMVTDPVTCRPDNTLAQVGALC
**.:*.: .
Mb2804c|M.bovis_AF2122/97 -------AQLEYYADELEEVAEYYHTEVGQPVYGDDDDWVRKLEVVADVR
Rv2781c|M.tuberculosis_H37Rv -------AQLEYYADELEEVAEYYHTEVGQPVYGDDDDWVRKLEVVADVR
MMAR_1927|M.marinum_M -------LQLEYYAEELAEVAEYYHVEVGQPIHGDDDEWERKLEVVADIR
MUL_2153|M.ulcerans_Agy99 -------LQLEYYAEELAEVAEYYHVEVGQPIHGDDDEWERKLEVVADIR
Mflv_2277|M.gilvum_PYR-GCK -------DEIAAYARALAPEAQRYGVAVGEPKF-DDDDWAAKIEVLLDLR
Mvan_4389|M.vanbaalenii_PYR-1 -------AAVAAYAERLAEEARRYGTELGAPRF-DDDHWNAKLEVVLDLR
MSMEG_4971|M.smegmatis_MC2_155 -------EQIAAYAQALAGEAERYGVALGEPRY-DDDAWAAKLDVVADLR
MAV_2990|M.avium_104 -------QRYRDYHGIIQREADQFGLTLPPQPVEDDDAFDEKIALLLDDP
MAB_1641|M.abscessus_ATCC_1997 -------ADLREYLDKLKVWADKLEVAPGDPVW-HDDAYADKIEYLVANP
TH_1758|M.thermoresistible__bu ----------------------------------DAGDANERVDLLIREG
MLBr_00387|M.leprae_Br4923 ARFRISGLPVVDDSGALAGIITNRDMRFEVDQSKQVAEVMTKTPLITAAE
. : :
Mb2804c|M.bovis_AF2122/97 PEVVSFTFGAPPPDVVQRLSALG---------------------------
Rv2781c|M.tuberculosis_H37Rv PEVVSFTFGAPPPDVVQRLSALG---------------------------
MMAR_1927|M.marinum_M PELVSFTFGAPPPDVVRQLSALG---------------------------
MUL_2153|M.ulcerans_Agy99 PELVSFTFGAPPPDVVRQLSALG---------------------------
Mflv_2277|M.gilvum_PYR-GCK PAVVSFTFGLPSAEERRRLTGAG---------------------------
Mvan_4389|M.vanbaalenii_PYR-1 PALASFTFGLPTVEERRRLSAAG---------------------------
MSMEG_4971|M.smegmatis_MC2_155 PEVVSFTFGLPDDDEVKRLRQAG---------------------------
MAV_2990|M.avium_104 VPLVSFTFGIPPREVIAALRRAE---------------------------
MAB_1641|M.abscessus_ATCC_1997 VPVVSFTFGVPTAPDAHRLREAG---------------------------
TH_1758|M.thermoresistible__bu VKVASFAL-APKPELIARLKDAG---------------------------
MLBr_00387|M.leprae_Br4923 GVSADAALGLLRRNKIEKLPVVDGHGRLTGLITVKDFVKTEQHPLATKDN
.. :: *
Mb2804c|M.bovis_AF2122/97 --------------------------------------------------
Rv2781c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1927|M.marinum_M --------------------------------------------------
MUL_2153|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2277|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4389|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4971|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2990|M.avium_104 --------------------------------------------------
MAB_1641|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1758|M.thermoresistible__bu --------------------------------------------------
MLBr_00387|M.leprae_Br4923 DGRLLVGAAVGVGGDAWVRAMMLVDAGVDVLIVDTAHAHNRLVLDMVGKL
Mb2804c|M.bovis_AF2122/97 --------LLVSITVTSVYEAGVAIAAGADSLVVQGPAAGGHRGTFAPDM
Rv2781c|M.tuberculosis_H37Rv --------LLVSITVTSVYEAGVAIAAGADSLVVQGPAAGGHRGTFAPDM
MMAR_1927|M.marinum_M --------LLVSVTVTSAYEAGVAIAAGADNLVVQGPGAGGHRGTFAPDT
MUL_2153|M.ulcerans_Agy99 --------LLVSVTVTSAYEAGVAIAAGADNLVVQGPGAGGHRGTFAPDT
Mflv_2277|M.gilvum_PYR-GCK --------ITTVGTVTTVAEARAAADVGVDVLTVQGPSAGGHRGTFDATA
Mvan_4389|M.vanbaalenii_PYR-1 --------IATAATVTTPAEARLAADCGVDILVAQGPSAGGHRGTFDPTA
MSMEG_4971|M.smegmatis_MC2_155 --------ITTVATVTSYDEAEQADGRGVDALAVQGPNAGGHRGTFDPAA
MAV_2990|M.avium_104 --------TVVAQTVTTADEAAQAHDAGVDMLVVQATAAGGHSATLSPQR
MAB_1641|M.abscessus_ATCC_1997 --------SEVWITVTSAAEAKIAEGIGADALVVQGPEAGGHRSSFDAGA
TH_1758|M.thermoresistible__bu --------VVVIPSVGAARHAEKVAGWGADAVIVQGGEGGGHTGPVP---
MLBr_00387|M.leprae_Br4923 KVEIGDRVQVIGGNVATRSAAAALVEAGADAVKVGVGPGSTCTTRVVAGV
.* : * *.* : . .. .
Mb2804c|M.bovis_AF2122/97 EPGTESLHQLLDRIGSAHDVPLVAAGGLGTAEDVAAVLRRGAIAAQVGTA
Rv2781c|M.tuberculosis_H37Rv EPGTESLHQLLDRIGSAHDVPLVAAGGLGTAEDVAAVLRRGAIAAQVGTA
MMAR_1927|M.marinum_M EPGEESLHQLLDHIGHTHDVPLIAAGGLGTADEVAAVLRRGAVAAQVGTA
MUL_2153|M.ulcerans_Agy99 EPGEESLHQLLDHIGHTHDVPLIGAGGLGTADEVAAVLRRGAVAAQVGTA
Mflv_2277|M.gilvum_PYR-GCK RPSDIALDDLIARVTAAVGLPVVAAGGIMDAADIRRVRDAGAVAAQLGTA
Mvan_4389|M.vanbaalenii_PYR-1 TPSGQPLDELLAAVTADHAIPVVAAGGLMTATDIRRVRQAGAAAAQLGTA
MSMEG_4971|M.smegmatis_MC2_155 APATQSLEELLDDVVAAMDMPVIAAGGLVTADDVAGVLAAGAVAAQLGTA
MAV_2990|M.avium_104 PVPSVPITDLVRQVTARVPLQVIATGGLATPAAVAEVIRAGAHAAAVGTV
MAB_1641|M.abscessus_ATCC_1997 P--DEPLLDLIASVRSVTALPVVAAGGIMDGADIARVLAAGAAAAQLGTA
TH_1758|M.thermoresistible__bu ---TTLLLPSVLDAVRDTGMPVVAAGGFFDGRGLAAALAYGAAGVAMGTR
MLBr_00387|M.leprae_Br4923 GAPQITAILEAVAACGPAGVPVIADGGLQYSGDIAKALAAGASTTMLGSL
: ::. **: : . ** . :*:
Mb2804c|M.bovis_AF2122/97 LLLADEAGTNAAHRAALKNPEFDATLVTRAFSGR--------------YA
Rv2781c|M.tuberculosis_H37Rv LLLADEAGTNAAHRAALKNPEFDATLVTRAFSGR--------------YA
MMAR_1927|M.marinum_M LLLADEAGTSSVHRVALKNPEFDSTLVTRAFSGR--------------YA
MUL_2153|M.ulcerans_Agy99 LLLADEAGTSSVHRVALKNPEFDSTLVTRAFSGR--------------YA
Mflv_2277|M.gilvum_PYR-GCK FLLADEAGSTPVHRAALQSSQFTETVVTRAFSGR--------------YA
Mvan_4389|M.vanbaalenii_PYR-1 FLLSDEAGSSPVHRAALIDPQFTETAVTKAFSGR--------------YA
MSMEG_4971|M.smegmatis_MC2_155 FLLAEEAGSSDVHRAALQNPEFTETVVTRAFSGR--------------YA
MAV_2990|M.avium_104 LLRATESGASATHQAALADPAYTETVLTRAFTGR--------------PA
MAB_1641|M.abscessus_ATCC_1997 LVVTDESGAKQVYKDALLQP--ADTVVTRVFSGR--------------PA
TH_1758|M.thermoresistible__bu FLLTKDSTVPDAVKRRYLEAGLDGTVVSTRVDGM--------------PH
MLBr_00387|M.leprae_Br4923 LAGTAEAPGELIFVNGKQFKSYRGMGSLGAMQGRGGDKSYSKDRYFADDA
: : :: . *
Mb2804c|M.bovis_AF2122/97 RGLANNFTRLLDHVAPLG-----------YPEVHQMTKP-----------
Rv2781c|M.tuberculosis_H37Rv RGLANNFTRLLDHVAPLG-----------YPEVHQMTKP-----------
MMAR_1927|M.marinum_M RGLANNFTRLLDRVAPLG-----------YPEVNQMTKP-----------
MUL_2153|M.ulcerans_Agy99 RGLANNFTRLLDRVAPLG-----------YPEVNQMTKP-----------
Mflv_2277|M.gilvum_PYR-GCK RGLRNRFIIEHESQAPFG-----------YPEVHYLTSP-----------
Mvan_4389|M.vanbaalenii_PYR-1 RGLRNRFIVEHEAEAPFG-----------YPEVHYLTSP-----------
MSMEG_4971|M.smegmatis_MC2_155 RGLRNRFVVDHEAQAPFG-----------YPEVHYLTSP-----------
MAV_2990|M.avium_104 RGLRNAFIDAHEAGAPLG-----------YPAIHHLTSP-----------
MAB_1641|M.abscessus_ATCC_1997 RSISNAFQRDMEAVAPVS-----------FPALNSATKE-----------
TH_1758|M.thermoresistible__bu RVLRTGLVEKLESGSPIRGFTAAVRNAQKFKKMTGMTWRSMIRDGLEMRR
MLBr_00387|M.leprae_Br4923 LSEDKLVPEGIEGRVPFRG--------PLSSVIHQLVGG-----------
. . : *. : .
Mb2804c|M.bovis_AF2122/97 -----------------IRAAAVQADDPHGTNLWAGSAHRKTRPGP-AAD
Rv2781c|M.tuberculosis_H37Rv -----------------IRAAAVQADDPHGTNLWAGSAHRKTRPGP-AAD
MMAR_1927|M.marinum_M -----------------IRAAAIEADDPHGTNLWAGTAYRAAQAGP-AAD
MUL_2153|M.ulcerans_Agy99 -----------------IRAAAIEADDPHGTNLWAGTAYRAAQAGP-AAD
Mflv_2277|M.gilvum_PYR-GCK -----------------LRKASANAGDPGAVNIWAGTGFRRARTGS-VAD
Mvan_4389|M.vanbaalenii_PYR-1 -----------------LRAAAVRAGDPQAVNIWAGTGFRQAGGGS-VRD
MSMEG_4971|M.smegmatis_MC2_155 -----------------VRKASVAAGDPHATNIWAGTGFRAIGPGT-VAE
MAV_2990|M.avium_104 -----------------LRKAAAAAARPEYVHLWAGSGYRHATAEP-AAD
MAB_1641|M.abscessus_ATCC_1997 -----------------LRAS----GDPDVMSLWAGTEHHRARALP-VAE
TH_1758|M.thermoresistible__bu GKDLTWAQVIMAANTPMLLKAGLVEGNTEAGVLASGQVAGILDDLPSCAE
MLBr_00387|M.leprae_Br4923 -----------------LRAAMGYTGSPTIEVLQQAQFVRITPAGLKESH
: : . : . .
Mb2804c|M.bovis_AF2122/97 IIASLTPDVCSA----------
Rv2781c|M.tuberculosis_H37Rv IIASLTPDVCSA----------
MMAR_1927|M.marinum_M IVAALAPDVWSL----------
MUL_2153|M.ulcerans_Agy99 IVAALAPNVWSL----------
Mflv_2277|M.gilvum_PYR-GCK IVGSLVGDG-------------
Mvan_4389|M.vanbaalenii_PYR-1 IMDTLIGRD-------------
MSMEG_4971|M.smegmatis_MC2_155 IMGRLVP---------------
MAV_2990|M.avium_104 ILRRLTSAL-------------
MAB_1641|M.abscessus_ATCC_1997 LMATLATELSAAQG--------
TH_1758|M.thermoresistible__bu LIEQIVADAVRHLKGAVALVEE
MLBr_00387|M.leprae_Br4923 PHDVAMTVEAPNYYPR------