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MLAQFGMSIPLVAAPMSGGPTTPAMVSAAARAGALGILAAGYKTVQGIEAEIKAVRAESIPFGVNLFAPN PVPVDPQRYRDYHGIIQREADQFGLTLPPQPVEDDDAFDEKIALLLDDPVPLVSFTFGIPPREVIAALRR AETVVAQTVTTADEAAQAHDAGVDMLVVQATAAGGHSATLSPQRPVPSVPITDLVRQVTARVPLQVIATG GLATPAAVAEVIRAGAHAAAVGTVLLRATESGASATHQAALADPAYTETVLTRAFTGRPARGLRNAFIDA HEAGAPLGYPAIHHLTSPLRKAAAAAARPEYVHLWAGSGYRHATAEPAADILRRLTSAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2990 | - | - | 100% (339) | oxidoreductase |
| M. avium 104 | MAV_3673 | - | 1e-60 | 38.76% (338) | dioxygenase |
| M. avium 104 | MAV_2807 | - | 4e-23 | 29.63% (297) | oxidoreductase, 2-nitropropane dioxygenase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2804c | - | 1e-66 | 40.95% (337) | alanine rich oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2277 | - | 5e-71 | 44.24% (330) | 2-nitropropane dioxygenase, NPD |
| M. tuberculosis H37Rv | Rv2781c | - | 1e-66 | 40.95% (337) | alanine rich oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1641 | - | 1e-59 | 40.42% (334) | putative oxidoreductase |
| M. marinum M | MMAR_1927 | - | 5e-66 | 41.84% (337) | hypothetical protein MMAR_1927 |
| M. smegmatis MC2 155 | MSMEG_4971 | - | 3e-77 | 46.22% (331) | oxidoreductase |
| M. thermoresistible (build 8) | TH_1530 | - | 5e-36 | 58.59% (128) | POSSIBLE ALANINE RICH OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_2153 | - | 1e-65 | 41.54% (337) | hypothetical protein MUL_2153 |
| M. vanbaalenii PYR-1 | Mvan_4389 | - | 1e-72 | 45.15% (330) | 2-nitropropane dioxygenase, NPD |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2804c|M.bovis_AF2122/97 MV--LGFWDIAVPIVGAPMAGGPSTPALAAAVSNAGGLGFVAGGYLSADR
Rv2781c|M.tuberculosis_H37Rv MV--LGFWDIAVPIVGAPMAGGPSTPALAAAVSNAGGLGFVAGGYLSADR
MMAR_1927|M.marinum_M MV--LGFWDIAVPIVGAPMAGGPGTPALAAAVSNAGGLGFVAGGYRTADQ
MUL_2153|M.ulcerans_Agy99 MV--LGFWDIAVPIVGAPMAGGPGTPALAAAVSNAGGLGFVAGGYRTADQ
MAB_1641|M.abscessus_ATCC_1997 MS--TVLAGLRLPVVGAPMAGGITVPALARGVSAAGGFGLLPAGYRTITQ
Mflv_2277|M.gilvum_PYR-GCK MP--FDLRELTVPVLVAPMAGGPSTPELAAAGSAAGGLGFVAAGYLTADM
Mvan_4389|M.vanbaalenii_PYR-1 MS--FDVRDLSVPVLVAPMAGGPSTPELAAAGTNAGGLGFVAAGYLTADV
MSMEG_4971|M.smegmatis_MC2_155 MMGDFDLRGLTRPVIVAPMAGGPSTPALAAAGSNAGGLGFIAAGYLTADA
MAV_2990|M.avium_104 ML---AQFGMSIPLVAAPMSGGPTTPAMVSAAARAGALGILAAGYKTVQG
TH_1530|M.thermoresistible__bu --------------------------------------------------
Mb2804c|M.bovis_AF2122/97 LADDIAAARAATTGPIGANLFVPQPSVADWAQLEYYADELEEVAEYYHTE
Rv2781c|M.tuberculosis_H37Rv LADDIAAARAATTGPIGANLFVPQPSVADWAQLEYYADELEEVAEYYHTE
MMAR_1927|M.marinum_M FADDISAARAATTGPIGANIFVPQPSVADWLQLEYYAEELAEVAEYYHVE
MUL_2153|M.ulcerans_Agy99 FADDISAARAATTGPIGANIFVPQPSVADWLQLEYYAEELAEVAEYYHVE
MAB_1641|M.abscessus_ATCC_1997 LEQDREAMGEL---PFGFNVFVPTPDQG--ADLREYLDKLKVWADKLEVA
Mflv_2277|M.gilvum_PYR-GCK FAEKLSAAMTLTREPVGANLFVPQPSAAMPDEIAAYARALAPEAQRYGVA
Mvan_4389|M.vanbaalenii_PYR-1 FAERVRAAQRLTSGPLGVNLFVPQPSAGTPAAVAAYAERLAEEARRYGTE
MSMEG_4971|M.smegmatis_MC2_155 LAERIKATRELTSEPIGVNLFAPQPSAGTPEQIAAYAQALAGEAERYGVA
MAV_2990|M.avium_104 IEAEIKAVRAES-IPFGVNLFAPNPVPVDPQRYRDYHGIIQREADQFGLT
TH_1530|M.thermoresistible__bu --------------------------------------------------
Mb2804c|M.bovis_AF2122/97 VGQPVYGDDDDWVRKLEVVADVRPEVVSFTFGAPPPDVVQRLSALGLLVS
Rv2781c|M.tuberculosis_H37Rv VGQPVYGDDDDWVRKLEVVADVRPEVVSFTFGAPPPDVVQRLSALGLLVS
MMAR_1927|M.marinum_M VGQPIHGDDDEWERKLEVVADIRPELVSFTFGAPPPDVVRQLSALGLLVS
MUL_2153|M.ulcerans_Agy99 VGQPIHGDDDEWERKLEVVADIRPELVSFTFGAPPPDVVRQLSALGLLVS
MAB_1641|M.abscessus_ATCC_1997 PGDPVWHDD-AYADKIEYLVANPVPVVSFTFGVPTAPDAHRLREAGSEVW
Mflv_2277|M.gilvum_PYR-GCK VGEPKFDDD-DWAAKIEVLLDLRPAVVSFTFGLPSAEERRRLTGAGITTV
Mvan_4389|M.vanbaalenii_PYR-1 LGAPRFDDD-HWNAKLEVVLDLRPALASFTFGLPTVEERRRLSAAGIATA
MSMEG_4971|M.smegmatis_MC2_155 LGEPRYDDD-AWAAKLDVVADLRPEVVSFTFGLPDDDEVKRLRQAGITTV
MAV_2990|M.avium_104 LPPQPVEDDDAFDEKIALLLDDPVPLVSFTFGIPPREVIAALRRAETVVA
TH_1530|M.thermoresistible__bu --------------------------------------------------
Mb2804c|M.bovis_AF2122/97 ITVTSVYEAGVAIAAGADSLVVQGPAAGGHRGTFAPDMEPGTESLHQLLD
Rv2781c|M.tuberculosis_H37Rv ITVTSVYEAGVAIAAGADSLVVQGPAAGGHRGTFAPDMEPGTESLHQLLD
MMAR_1927|M.marinum_M VTVTSAYEAGVAIAAGADNLVVQGPGAGGHRGTFAPDTEPGEESLHQLLD
MUL_2153|M.ulcerans_Agy99 VTVTSAYEAGVAIAAGADNLVVQGPGAGGHRGTFAPDTEPGEESLHQLLD
MAB_1641|M.abscessus_ATCC_1997 ITVTSAAEAKIAEGIGADALVVQGPEAGGHRSSFDAGAP--DEPLLDLIA
Mflv_2277|M.gilvum_PYR-GCK GTVTTVAEARAAADVGVDVLTVQGPSAGGHRGTFDATARPSDIALDDLIA
Mvan_4389|M.vanbaalenii_PYR-1 ATVTTPAEARLAADCGVDILVAQGPSAGGHRGTFDPTATPSGQPLDELLA
MSMEG_4971|M.smegmatis_MC2_155 ATVTSYDEAEQADGRGVDALAVQGPNAGGHRGTFDPAAAPATQSLEELLD
MAV_2990|M.avium_104 QTVTTADEAAQAHDAGVDMLVVQATAAGGHSATLSPQRPVPSVPITDLVR
TH_1530|M.thermoresistible__bu --------------------------------------------------
Mb2804c|M.bovis_AF2122/97 RIGSAHDVPLVAAGGLGTAEDVAAVLRRGAIAAQVGTALLLADEAGTNAA
Rv2781c|M.tuberculosis_H37Rv RIGSAHDVPLVAAGGLGTAEDVAAVLRRGAIAAQVGTALLLADEAGTNAA
MMAR_1927|M.marinum_M HIGHTHDVPLIAAGGLGTADEVAAVLRRGAVAAQVGTALLLADEAGTSSV
MUL_2153|M.ulcerans_Agy99 HIGHTHDVPLIGAGGLGTADEVAAVLRRGAVAAQVGTALLLADEAGTSSV
MAB_1641|M.abscessus_ATCC_1997 SVRSVTALPVVAAGGIMDGADIARVLAAGAAAAQLGTALVVTDESGAKQV
Mflv_2277|M.gilvum_PYR-GCK RVTAAVGLPVVAAGGIMDAADIRRVRDAGAVAAQLGTAFLLADEAGSTPV
Mvan_4389|M.vanbaalenii_PYR-1 AVTADHAIPVVAAGGLMTATDIRRVRQAGAAAAQLGTAFLLSDEAGSSPV
MSMEG_4971|M.smegmatis_MC2_155 DVVAAMDMPVIAAGGLVTADDVAGVLAAGAVAAQLGTAFLLAEEAGSSDV
MAV_2990|M.avium_104 QVTARVPLQVIATGGLATPAAVAEVIRAGAHAAAVGTVLLRATESGASAT
TH_1530|M.thermoresistible__bu ---------------LVTAXGVAGAISAGAVAVQAGTAFLLADEAGTGPT
: : . ** *. **.:: : *:*: .
Mb2804c|M.bovis_AF2122/97 HRAALKNPEFDATLVTRAFSGRYARGLANNFTRLLDHVAPLGYPEVHQMT
Rv2781c|M.tuberculosis_H37Rv HRAALKNPEFDATLVTRAFSGRYARGLANNFTRLLDHVAPLGYPEVHQMT
MMAR_1927|M.marinum_M HRVALKNPEFDSTLVTRAFSGRYARGLANNFTRLLDRVAPLGYPEVNQMT
MUL_2153|M.ulcerans_Agy99 HRVALKNPEFDSTLVTRAFSGRYARGLANNFTRLLDRVAPLGYPEVNQMT
MAB_1641|M.abscessus_ATCC_1997 YKDALLQP--ADTVVTRVFSGRPARSISNAFQRDMEAVAPVSFPALNSAT
Mflv_2277|M.gilvum_PYR-GCK HRAALQSSQFTETVVTRAFSGRYARGLRNRFIIEHESQAPFGYPEVHYLT
Mvan_4389|M.vanbaalenii_PYR-1 HRAALIDPQFTETAVTKAFSGRYARGLRNRFIVEHEAEAPFGYPEVHYLT
MSMEG_4971|M.smegmatis_MC2_155 HRAALQNPEFTETVVTRAFSGRYARGLRNRFVVDHEAQAPFGYPEVHYLT
MAV_2990|M.avium_104 HQAALADPAYTETVLTRAFTGRPARGLRNAFIDAHEAGAPLGYPAIHHLT
TH_1530|M.thermoresistible__bu QRAALRDPQFTETALTRAFSGRYARGLRNRFIDEHEDAAPFGYPQVHHLT
: ** .. * :*:.*:** **.: * * : **..:* :: *
Mb2804c|M.bovis_AF2122/97 KPIRAAAVQADDPHGTNLWAGSAHRKTRPGPAADIIASLTPDVCSA--
Rv2781c|M.tuberculosis_H37Rv KPIRAAAVQADDPHGTNLWAGSAHRKTRPGPAADIIASLTPDVCSA--
MMAR_1927|M.marinum_M KPIRAAAIEADDPHGTNLWAGTAYRAAQAGPAADIVAALAPDVWSL--
MUL_2153|M.ulcerans_Agy99 KPIRAAAIEADDPHGTNLWAGTAYRAAQAGPAADIVAALAPNVWSL--
MAB_1641|M.abscessus_ATCC_1997 KELRAS----GDPDVMSLWAGTEHHRARALPVAELMATLATELSAAQG
Mflv_2277|M.gilvum_PYR-GCK SPLRKASANAGDPGAVNIWAGTGFRRARTGSVADIVGSLVGDG-----
Mvan_4389|M.vanbaalenii_PYR-1 SPLRAAAVRAGDPQAVNIWAGTGFRQAGGGSVRDIMDTLIGRD-----
MSMEG_4971|M.smegmatis_MC2_155 SPVRKASVAAGDPHATNIWAGTGFRAIGPGTVAEIMGRLVP-------
MAV_2990|M.avium_104 SPLRKAAAAAARPEYVHLWAGSGYRHATAEPAADILRRLTSAL-----
TH_1530|M.thermoresistible__bu SPVRAAAARAGDPHGTNVWAGTGYRSITAGPAADILTGLAAELPARS-
. :* : * :***: .: .. ::: *