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SFDVRDLSVPVLVAPMAGGPSTPELAAAGTNAGGLGFVAAGYLTADVFAERVRAAQRLTSGPLGVNLFVP QPSAGTPAAVAAYAERLAEEARRYGTELGAPRFDDDHWNAKLEVVLDLRPALASFTFGLPTVEERRRLSA AGIATAATVTTPAEARLAADCGVDILVAQGPSAGGHRGTFDPTATPSGQPLDELLAAVTADHAIPVVAAG GLMTATDIRRVRQAGAAAAQLGTAFLLSDEAGSSPVHRAALIDPQFTETAVTKAFSGRYARGLRNRFIVE HEAEAPFGYPEVHYLTSPLRAAAVRAGDPQAVNIWAGTGFRQAGGGSVRDIMDTLIGRD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4389 | - | - | 100% (340) | 2-nitropropane dioxygenase, NPD |
| M. vanbaalenii PYR-1 | Mvan_4537 | - | 1e-19 | 31.94% (263) | 2-nitropropane dioxygenase, NPD |
| M. vanbaalenii PYR-1 | Mvan_3005 | - | 4e-19 | 26.02% (319) | 2-nitropropane dioxygenase, NPD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2804c | - | 5e-97 | 54.68% (331) | alanine rich oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2277 | - | 1e-141 | 73.81% (336) | 2-nitropropane dioxygenase, NPD |
| M. tuberculosis H37Rv | Rv2781c | - | 5e-97 | 54.68% (331) | alanine rich oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1641 | - | 5e-62 | 42.86% (329) | putative oxidoreductase |
| M. marinum M | MMAR_1927 | - | 3e-97 | 54.38% (331) | hypothetical protein MMAR_1927 |
| M. avium 104 | MAV_3673 | - | 5e-85 | 49.39% (328) | dioxygenase |
| M. smegmatis MC2 155 | MSMEG_4971 | - | 1e-130 | 68.66% (335) | oxidoreductase |
| M. thermoresistible (build 8) | TH_1530 | - | 3e-43 | 66.13% (124) | POSSIBLE ALANINE RICH OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_2153 | - | 7e-97 | 54.08% (331) | hypothetical protein MUL_2153 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2804c|M.bovis_AF2122/97 --MVLGFWDIAVPIVGAPMAGGPSTPALAAAVSNAGGLGFVAGGYLSADR
Rv2781c|M.tuberculosis_H37Rv --MVLGFWDIAVPIVGAPMAGGPSTPALAAAVSNAGGLGFVAGGYLSADR
MMAR_1927|M.marinum_M --MVLGFWDIAVPIVGAPMAGGPGTPALAAAVSNAGGLGFVAGGYRTADQ
MUL_2153|M.ulcerans_Agy99 --MVLGFWDIAVPIVGAPMAGGPGTPALAAAVSNAGGLGFVAGGYRTADQ
MAV_3673|M.avium_104 --MVLGFWDITVPIVGAPMAGGPGTPALAAAVSNAGGLGFVPGGYVSAEQ
Mvan_4389|M.vanbaalenii_PYR-1 MS--FDVRDLSVPVLVAPMAGGPSTPELAAAGTNAGGLGFVAAGYLTADV
Mflv_2277|M.gilvum_PYR-GCK MP--FDLRELTVPVLVAPMAGGPSTPELAAAGSAAGGLGFVAAGYLTADM
MSMEG_4971|M.smegmatis_MC2_155 MMGDFDLRGLTRPVIVAPMAGGPSTPALAAAGSNAGGLGFIAAGYLTADA
TH_1530|M.thermoresistible__bu --------------------------------------------------
MAB_1641|M.abscessus_ATCC_1997 --MSTVLAGLRLPVVGAPMAGGITVPALARGVSAAGGFGLLPAGYRTITQ
Mb2804c|M.bovis_AF2122/97 LADDIAAARAATTGPIGANLFVPQPSVADWAQLEYYADELEEVAEYYHTE
Rv2781c|M.tuberculosis_H37Rv LADDIAAARAATTGPIGANLFVPQPSVADWAQLEYYADELEEVAEYYHTE
MMAR_1927|M.marinum_M FADDISAARAATTGPIGANIFVPQPSVADWLQLEYYAEELAEVAEYYHVE
MUL_2153|M.ulcerans_Agy99 FADDISAARAATTGPIGANIFVPQPSVADWLQLEYYAEELAEVAEYYHVE
MAV_3673|M.avium_104 FADDIAAARKATTGPLGVNLFVPQPSVADWVALDYYAAELEEIAEHYQVE
Mvan_4389|M.vanbaalenii_PYR-1 FAERVRAAQRLTSGPLGVNLFVPQPSAGTPAAVAAYAERLAEEARRYGTE
Mflv_2277|M.gilvum_PYR-GCK FAEKLSAAMTLTREPVGANLFVPQPSAAMPDEIAAYARALAPEAQRYGVA
MSMEG_4971|M.smegmatis_MC2_155 LAERIKATRELTSEPIGVNLFAPQPSAGTPEQIAAYAQALAGEAERYGVA
TH_1530|M.thermoresistible__bu --------------------------------------------------
MAB_1641|M.abscessus_ATCC_1997 LEQDREAMGEL---PFGFNVFVPTPDQG--ADLREYLDKLKVWADKLEVA
Mb2804c|M.bovis_AF2122/97 VGQPVYGDDDDWVRKLEVVADVRPEVVSFTFGAPPPDVVQRLSALGLLVS
Rv2781c|M.tuberculosis_H37Rv VGQPVYGDDDDWVRKLEVVADVRPEVVSFTFGAPPPDVVQRLSALGLLVS
MMAR_1927|M.marinum_M VGQPIHGDDDEWERKLEVVADIRPELVSFTFGAPPPDVVRQLSALGLLVS
MUL_2153|M.ulcerans_Agy99 VGQPIHGDDDEWERKLEVVADIRPELVSFTFGAPPPDVVRQLSALGLLVS
MAV_3673|M.avium_104 VGHPRYGDDDGWEQKLEVVADVRPELVSFTFGVPPPDVIRRLGALGLLVM
Mvan_4389|M.vanbaalenii_PYR-1 LGAPRF-DDDHWNAKLEVVLDLRPALASFTFGLPTVEERRRLSAAGIATA
Mflv_2277|M.gilvum_PYR-GCK VGEPKF-DDDDWAAKIEVLLDLRPAVVSFTFGLPSAEERRRLTGAGITTV
MSMEG_4971|M.smegmatis_MC2_155 LGEPRY-DDDAWAAKLDVVADLRPEVVSFTFGLPDDDEVKRLRQAGITTV
TH_1530|M.thermoresistible__bu --------------------------------------------------
MAB_1641|M.abscessus_ATCC_1997 PGDPVW-HDDAYADKIEYLVANPVPVVSFTFGVPTAPDAHRLREAGSEVW
Mb2804c|M.bovis_AF2122/97 ITVTSVYEAGVAIAAGADSLVVQGPAAGGHRGTFAPDMEPGTESLHQLLD
Rv2781c|M.tuberculosis_H37Rv ITVTSVYEAGVAIAAGADSLVVQGPAAGGHRGTFAPDMEPGTESLHQLLD
MMAR_1927|M.marinum_M VTVTSAYEAGVAIAAGADNLVVQGPGAGGHRGTFAPDTEPGEESLHQLLD
MUL_2153|M.ulcerans_Agy99 VTVTSAYEAGVAIAAGADNLVVQGPGAGGHRGTFAPDTEPGEESLHQLLD
MAV_3673|M.avium_104 VTVTSAYEAGVAVAAGADSLVVQGPAAGGHRGTFAPDMEPANESLHQLID
Mvan_4389|M.vanbaalenii_PYR-1 ATVTTPAEARLAADCGVDILVAQGPSAGGHRGTFDPTATPSGQPLDELLA
Mflv_2277|M.gilvum_PYR-GCK GTVTTVAEARAAADVGVDVLTVQGPSAGGHRGTFDATARPSDIALDDLIA
MSMEG_4971|M.smegmatis_MC2_155 ATVTSYDEAEQADGRGVDALAVQGPNAGGHRGTFDPAAAPATQSLEELLD
TH_1530|M.thermoresistible__bu --------------------------------------------------
MAB_1641|M.abscessus_ATCC_1997 ITVTSAAEAKIAEGIGADALVVQGPEAGGHRSSFDAGAP--DEPLLDLIA
Mb2804c|M.bovis_AF2122/97 RIGSAHDVPLVAAGGLGTAEDVAAVLRRGAIAAQVGTALLLADEAGTNAA
Rv2781c|M.tuberculosis_H37Rv RIGSAHDVPLVAAGGLGTAEDVAAVLRRGAIAAQVGTALLLADEAGTNAA
MMAR_1927|M.marinum_M HIGHTHDVPLIAAGGLGTADEVAAVLRRGAVAAQVGTALLLADEAGTSSV
MUL_2153|M.ulcerans_Agy99 HIGHTHDVPLIGAGGLGTADEVAAVLRRGAVAAQVGTALLLADEAGTSSV
MAV_3673|M.avium_104 RIRHTHDIPIIAAGGLGTADEVGAALRRGAVAAQVGTALLLADEAGTNAA
Mvan_4389|M.vanbaalenii_PYR-1 AVTADHAIPVVAAGGLMTATDIRRVRQAGAAAAQLGTAFLLSDEAGSSPV
Mflv_2277|M.gilvum_PYR-GCK RVTAAVGLPVVAAGGIMDAADIRRVRDAGAVAAQLGTAFLLADEAGSTPV
MSMEG_4971|M.smegmatis_MC2_155 DVVAAMDMPVIAAGGLVTADDVAGVLAAGAVAAQLGTAFLLAEEAGSSDV
TH_1530|M.thermoresistible__bu ---------------LVTAXGVAGAISAGAVAVQAGTAFLLADEAGTGPT
MAB_1641|M.abscessus_ATCC_1997 SVRSVTALPVVAAGGIMDGADIARVLAAGAAAAQLGTALVVTDESGAKQV
: . : . ** *.* ***:::::*:*: .
Mb2804c|M.bovis_AF2122/97 HRAALKNPEFDATLVTRAFSGRYARGLANNFTRLLDHVAPLGYPEVHQMT
Rv2781c|M.tuberculosis_H37Rv HRAALKNPEFDATLVTRAFSGRYARGLANNFTRLLDHVAPLGYPEVHQMT
MMAR_1927|M.marinum_M HRVALKNPEFDSTLVTRAFSGRYARGLANNFTRLLDRVAPLGYPEVNQMT
MUL_2153|M.ulcerans_Agy99 HRVALKNPEFDSTLVTRAFSGRYARGLANNFTRLLDRVAPLGYPEVNQMT
MAV_3673|M.avium_104 HRTALKNPLFAT-----------ARGLENDFTRMLDHVAPLGYPEVNQMT
Mvan_4389|M.vanbaalenii_PYR-1 HRAALIDPQFTETAVTKAFSGRYARGLRNRFIVEHEAEAPFGYPEVHYLT
Mflv_2277|M.gilvum_PYR-GCK HRAALQSSQFTETVVTRAFSGRYARGLRNRFIIEHESQAPFGYPEVHYLT
MSMEG_4971|M.smegmatis_MC2_155 HRAALQNPEFTETVVTRAFSGRYARGLRNRFVVDHEAQAPFGYPEVHYLT
TH_1530|M.thermoresistible__bu QRAALRDPQFTETALTRAFSGRYARGLRNRFIDEHEDAAPFGYPQVHHLT
MAB_1641|M.abscessus_ATCC_1997 YKDALLQP--ADTVVTRVFSGRPARSISNAFQRDMEAVAPVSFPALNSAT
: ** .. **.: * * : **..:* :: *
Mb2804c|M.bovis_AF2122/97 KPIRAAAVQADDPHGTNLWAGSAHRKTRPGPAADIIASLTPDVCSA--
Rv2781c|M.tuberculosis_H37Rv KPIRAAAVQADDPHGTNLWAGSAHRKTRPGPAADIIASLTPDVCSA--
MMAR_1927|M.marinum_M KPIRAAAIEADDPHGTNLWAGTAYRAAQAGPAADIVAALAPDVWSL--
MUL_2153|M.ulcerans_Agy99 KPIRAAAIEADDPHGTNLWAGTAYRAAQAGPAADIVAALAPNVWSL--
MAV_3673|M.avium_104 TPIVEAAAAIEDPNGIPLWAGAAFKHASAGPAADIIAGLAATG-----
Mvan_4389|M.vanbaalenii_PYR-1 SPLRAAAVRAGDPQAVNIWAGTGFRQAGGGSVRDIMDTLIGRD-----
Mflv_2277|M.gilvum_PYR-GCK SPLRKASANAGDPGAVNIWAGTGFRRARTGSVADIVGSLVGDG-----
MSMEG_4971|M.smegmatis_MC2_155 SPVRKASVAAGDPHATNIWAGTGFRAIGPGTVAEIMGRLVP-------
TH_1530|M.thermoresistible__bu SPVRAAAARAGDPHGTNVWAGTGYRSITAGPAADILTGLAAELPARS-
MAB_1641|M.abscessus_ATCC_1997 KELRAS----GDPDVMSLWAGTEHHRARALPVAELMATLATELSAAQG
. : : ** :***: .: .. ::: *