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M. bovis AF2122 / 97 Mb2804c (-)

annotation: alanine rich oxidoreductase
coordinates: 3044499 - 3045533
length: 344

MVLGFWDIAVPIVGAPMAGGPSTPALAAAVSNAGGLGFVAGGYLSADRLADDIAAARAATTGPIGANLFV
PQPSVADWAQLEYYADELEEVAEYYHTEVGQPVYGDDDDWVRKLEVVADVRPEVVSFTFGAPPPDVVQRL
SALGLLVSITVTSVYEAGVAIAAGADSLVVQGPAAGGHRGTFAPDMEPGTESLHQLLDRIGSAHDVPLVA
AGGLGTAEDVAAVLRRGAIAAQVGTALLLADEAGTNAAHRAALKNPEFDATLVTRAFSGRYARGLANNFT
RLLDHVAPLGYPEVHQMTKPIRAAAVQADDPHGTNLWAGSAHRKTRPGPAADIIASLTPDVCSA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2804c--100% (344)alanine rich oxidoreductase
M. bovis AF2122 / 97Mb1927c-3e-1727.46% (295) hypothetical protein Mb1927c
M. bovis AF2122 / 97Mb3583-4e-1726.64% (274) oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2277-7e-9452.99% (334) 2-nitropropane dioxygenase, NPD
M. tuberculosis H37RvRv2781c-0.0100.00% (344) alanine rich oxidoreductase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1641-4e-6242.65% (340) putative oxidoreductase
M. marinum MMMAR_1927-1e-17385.13% (343) hypothetical protein MMAR_1927
M. avium 104MAV_3673-1e-14675.37% (337) dioxygenase
M. smegmatis MC2 155MSMEG_4971-1e-10558.06% (341) oxidoreductase
M. thermoresistible (build 8)TH_1530-1e-3756.25% (128) POSSIBLE ALANINE RICH OXIDOREDUCTASE
M. ulcerans Agy99MUL_2153-1e-17284.55% (343) hypothetical protein MUL_2153
M. vanbaalenii PYR-1Mvan_4389-7e-9754.68% (331) 2-nitropropane dioxygenase, NPD

CLUSTAL 2.0.9 multiple sequence alignment


Mb2804c|M.bovis_AF2122/97           --MVLGFWDIAVPIVGAPMAGGPSTPALAAAVSNAGGLGFVAGGYLSADR
Rv2781c|M.tuberculosis_H37Rv        --MVLGFWDIAVPIVGAPMAGGPSTPALAAAVSNAGGLGFVAGGYLSADR
MMAR_1927|M.marinum_M               --MVLGFWDIAVPIVGAPMAGGPGTPALAAAVSNAGGLGFVAGGYRTADQ
MUL_2153|M.ulcerans_Agy99           --MVLGFWDIAVPIVGAPMAGGPGTPALAAAVSNAGGLGFVAGGYRTADQ
MAV_3673|M.avium_104                --MVLGFWDITVPIVGAPMAGGPGTPALAAAVSNAGGLGFVPGGYVSAEQ
Mflv_2277|M.gilvum_PYR-GCK          MP--FDLRELTVPVLVAPMAGGPSTPELAAAGSAAGGLGFVAAGYLTADM
Mvan_4389|M.vanbaalenii_PYR-1       MS--FDVRDLSVPVLVAPMAGGPSTPELAAAGTNAGGLGFVAAGYLTADV
MSMEG_4971|M.smegmatis_MC2_155      MMGDFDLRGLTRPVIVAPMAGGPSTPALAAAGSNAGGLGFIAAGYLTADA
TH_1530|M.thermoresistible__bu      --------------------------------------------------
MAB_1641|M.abscessus_ATCC_1997      --MSTVLAGLRLPVVGAPMAGGITVPALARGVSAAGGFGLLPAGYRTITQ
                                                                                      

Mb2804c|M.bovis_AF2122/97           LADDIAAARAATTGPIGANLFVPQPSVADWAQLEYYADELEEVAEYYHTE
Rv2781c|M.tuberculosis_H37Rv        LADDIAAARAATTGPIGANLFVPQPSVADWAQLEYYADELEEVAEYYHTE
MMAR_1927|M.marinum_M               FADDISAARAATTGPIGANIFVPQPSVADWLQLEYYAEELAEVAEYYHVE
MUL_2153|M.ulcerans_Agy99           FADDISAARAATTGPIGANIFVPQPSVADWLQLEYYAEELAEVAEYYHVE
MAV_3673|M.avium_104                FADDIAAARKATTGPLGVNLFVPQPSVADWVALDYYAAELEEIAEHYQVE
Mflv_2277|M.gilvum_PYR-GCK          FAEKLSAAMTLTREPVGANLFVPQPSAAMPDEIAAYARALAPEAQRYGVA
Mvan_4389|M.vanbaalenii_PYR-1       FAERVRAAQRLTSGPLGVNLFVPQPSAGTPAAVAAYAERLAEEARRYGTE
MSMEG_4971|M.smegmatis_MC2_155      LAERIKATRELTSEPIGVNLFAPQPSAGTPEQIAAYAQALAGEAERYGVA
TH_1530|M.thermoresistible__bu      --------------------------------------------------
MAB_1641|M.abscessus_ATCC_1997      LEQDREAMGEL---PFGFNVFVPTPDQG--ADLREYLDKLKVWADKLEVA
                                                                                      

Mb2804c|M.bovis_AF2122/97           VGQPVYGDDDDWVRKLEVVADVRPEVVSFTFGAPPPDVVQRLSALGLLVS
Rv2781c|M.tuberculosis_H37Rv        VGQPVYGDDDDWVRKLEVVADVRPEVVSFTFGAPPPDVVQRLSALGLLVS
MMAR_1927|M.marinum_M               VGQPIHGDDDEWERKLEVVADIRPELVSFTFGAPPPDVVRQLSALGLLVS
MUL_2153|M.ulcerans_Agy99           VGQPIHGDDDEWERKLEVVADIRPELVSFTFGAPPPDVVRQLSALGLLVS
MAV_3673|M.avium_104                VGHPRYGDDDGWEQKLEVVADVRPELVSFTFGVPPPDVIRRLGALGLLVM
Mflv_2277|M.gilvum_PYR-GCK          VGEPKF-DDDDWAAKIEVLLDLRPAVVSFTFGLPSAEERRRLTGAGITTV
Mvan_4389|M.vanbaalenii_PYR-1       LGAPRF-DDDHWNAKLEVVLDLRPALASFTFGLPTVEERRRLSAAGIATA
MSMEG_4971|M.smegmatis_MC2_155      LGEPRY-DDDAWAAKLDVVADLRPEVVSFTFGLPDDDEVKRLRQAGITTV
TH_1530|M.thermoresistible__bu      --------------------------------------------------
MAB_1641|M.abscessus_ATCC_1997      PGDPVW-HDDAYADKIEYLVANPVPVVSFTFGVPTAPDAHRLREAGSEVW
                                                                                      

Mb2804c|M.bovis_AF2122/97           ITVTSVYEAGVAIAAGADSLVVQGPAAGGHRGTFAPDMEPGTESLHQLLD
Rv2781c|M.tuberculosis_H37Rv        ITVTSVYEAGVAIAAGADSLVVQGPAAGGHRGTFAPDMEPGTESLHQLLD
MMAR_1927|M.marinum_M               VTVTSAYEAGVAIAAGADNLVVQGPGAGGHRGTFAPDTEPGEESLHQLLD
MUL_2153|M.ulcerans_Agy99           VTVTSAYEAGVAIAAGADNLVVQGPGAGGHRGTFAPDTEPGEESLHQLLD
MAV_3673|M.avium_104                VTVTSAYEAGVAVAAGADSLVVQGPAAGGHRGTFAPDMEPANESLHQLID
Mflv_2277|M.gilvum_PYR-GCK          GTVTTVAEARAAADVGVDVLTVQGPSAGGHRGTFDATARPSDIALDDLIA
Mvan_4389|M.vanbaalenii_PYR-1       ATVTTPAEARLAADCGVDILVAQGPSAGGHRGTFDPTATPSGQPLDELLA
MSMEG_4971|M.smegmatis_MC2_155      ATVTSYDEAEQADGRGVDALAVQGPNAGGHRGTFDPAAAPATQSLEELLD
TH_1530|M.thermoresistible__bu      --------------------------------------------------
MAB_1641|M.abscessus_ATCC_1997      ITVTSAAEAKIAEGIGADALVVQGPEAGGHRSSFDAGAP--DEPLLDLIA
                                                                                      

Mb2804c|M.bovis_AF2122/97           RIGSAHDVPLVAAGGLGTAEDVAAVLRRGAIAAQVGTALLLADEAGTNAA
Rv2781c|M.tuberculosis_H37Rv        RIGSAHDVPLVAAGGLGTAEDVAAVLRRGAIAAQVGTALLLADEAGTNAA
MMAR_1927|M.marinum_M               HIGHTHDVPLIAAGGLGTADEVAAVLRRGAVAAQVGTALLLADEAGTSSV
MUL_2153|M.ulcerans_Agy99           HIGHTHDVPLIGAGGLGTADEVAAVLRRGAVAAQVGTALLLADEAGTSSV
MAV_3673|M.avium_104                RIRHTHDIPIIAAGGLGTADEVGAALRRGAVAAQVGTALLLADEAGTNAA
Mflv_2277|M.gilvum_PYR-GCK          RVTAAVGLPVVAAGGIMDAADIRRVRDAGAVAAQLGTAFLLADEAGSTPV
Mvan_4389|M.vanbaalenii_PYR-1       AVTADHAIPVVAAGGLMTATDIRRVRQAGAAAAQLGTAFLLSDEAGSSPV
MSMEG_4971|M.smegmatis_MC2_155      DVVAAMDMPVIAAGGLVTADDVAGVLAAGAVAAQLGTAFLLAEEAGSSDV
TH_1530|M.thermoresistible__bu      ---------------LVTAXGVAGAISAGAVAVQAGTAFLLADEAGTGPT
MAB_1641|M.abscessus_ATCC_1997      SVRSVTALPVVAAGGIMDGADIARVLAAGAAAAQLGTALVVTDESGAKQV
                                                   :  .  :  .   ** *.* ***:::::*:*:  .

Mb2804c|M.bovis_AF2122/97           HRAALKNPEFDATLVTRAFSGRYARGLANNFTRLLDHVAPLGYPEVHQMT
Rv2781c|M.tuberculosis_H37Rv        HRAALKNPEFDATLVTRAFSGRYARGLANNFTRLLDHVAPLGYPEVHQMT
MMAR_1927|M.marinum_M               HRVALKNPEFDSTLVTRAFSGRYARGLANNFTRLLDRVAPLGYPEVNQMT
MUL_2153|M.ulcerans_Agy99           HRVALKNPEFDSTLVTRAFSGRYARGLANNFTRLLDRVAPLGYPEVNQMT
MAV_3673|M.avium_104                HRTALKNPLFAT-----------ARGLENDFTRMLDHVAPLGYPEVNQMT
Mflv_2277|M.gilvum_PYR-GCK          HRAALQSSQFTETVVTRAFSGRYARGLRNRFIIEHESQAPFGYPEVHYLT
Mvan_4389|M.vanbaalenii_PYR-1       HRAALIDPQFTETAVTKAFSGRYARGLRNRFIVEHEAEAPFGYPEVHYLT
MSMEG_4971|M.smegmatis_MC2_155      HRAALQNPEFTETVVTRAFSGRYARGLRNRFVVDHEAQAPFGYPEVHYLT
TH_1530|M.thermoresistible__bu      QRAALRDPQFTETALTRAFSGRYARGLRNRFIDEHEDAAPFGYPQVHHLT
MAB_1641|M.abscessus_ATCC_1997      YKDALLQP--ADTVVTRVFSGRPARSISNAFQRDMEAVAPVSFPALNSAT
                                     : ** ..               **.: * *    :  **..:* ::  *

Mb2804c|M.bovis_AF2122/97           KPIRAAAVQADDPHGTNLWAGSAHRKTRPGPAADIIASLTPDVCSA--
Rv2781c|M.tuberculosis_H37Rv        KPIRAAAVQADDPHGTNLWAGSAHRKTRPGPAADIIASLTPDVCSA--
MMAR_1927|M.marinum_M               KPIRAAAIEADDPHGTNLWAGTAYRAAQAGPAADIVAALAPDVWSL--
MUL_2153|M.ulcerans_Agy99           KPIRAAAIEADDPHGTNLWAGTAYRAAQAGPAADIVAALAPNVWSL--
MAV_3673|M.avium_104                TPIVEAAAAIEDPNGIPLWAGAAFKHASAGPAADIIAGLAATG-----
Mflv_2277|M.gilvum_PYR-GCK          SPLRKASANAGDPGAVNIWAGTGFRRARTGSVADIVGSLVGDG-----
Mvan_4389|M.vanbaalenii_PYR-1       SPLRAAAVRAGDPQAVNIWAGTGFRQAGGGSVRDIMDTLIGRD-----
MSMEG_4971|M.smegmatis_MC2_155      SPVRKASVAAGDPHATNIWAGTGFRAIGPGTVAEIMGRLVP-------
TH_1530|M.thermoresistible__bu      SPVRAAAARAGDPHGTNVWAGTGYRSITAGPAADILTGLAAELPARS-
MAB_1641|M.abscessus_ATCC_1997      KELRAS----GDPDVMSLWAGTEHHRARALPVAELMATLATELSAAQG
                                    . :  :     **    :***: .:     .. :::  *