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MKVSRSSHRGRTRDHGEIRRRILDAAEECLLEHGYEARLHALIAKKAGLSRPTVYKHVGDQAAIIEALFH REFLRFGEMLEPVFAAAKNPRTGFIDAIVRIVQHGRHHPLLQKGLKENPEQVLPYLTVKARPFIDQTTIL LAPYFRQLLTEEQLASINVKAAAEWSFRIAASLLVTPGVVETQTDEQLGDFIGNLLKVSAITEEISATVL APDSAAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1036 | - | - | 100% (217) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2152 | - | 7e-15 | 31.82% (176) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1024 | - | 8e-13 | 30.71% (127) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2274c | - | 1e-05 | 36.84% (57) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2773 | - | 1e-10 | 32.17% (115) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 2e-07 | 25.00% (172) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00064 | - | 2e-05 | 31.87% (91) | putative transcriptional regulator |
| M. marinum M | MMAR_4185 | - | 3e-11 | 30.23% (172) | transcriptional regulatory protein |
| M. avium 104 | MAV_2157 | - | 2e-10 | 28.26% (184) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4333 | - | 1e-09 | 25.77% (194) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3720 | - | 1e-10 | 28.09% (178) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4487 | - | 2e-11 | 30.23% (172) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4342 | - | 4e-10 | 27.17% (173) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2274c|M.bovis_AF2122/97 -----------------MLSMSNDRADT--GGRILRAAASCVVDYGVDRV
MSMEG_4333|M.smegmatis_MC2_155 -----------------MVSISNDDAGESLGERILEAAASCVMAFGVDRV
Mflv_2773|M.gilvum_PYR-GCK -----------------MMSIRNSEPVE---QRILDAAAECIRAYGVERT
MMAR_4185|M.marinum_M ---------------MGRTDWLAAHRSEVAADRILDAAERLYTEHDPASI
MUL_4487|M.ulcerans_Agy99 ---------------MGRTDWLAAHRSEVAADRILDAAERLYTEHDPASI
Rv1255c|M.tuberculosis_H37Rv ---------------MAGTDWLSARRTELAADRILDAAERLFTQRDPASI
MAB_1036|M.abscessus_ATCC_1997 ------------MKVSRSSHRGRTRDHGEIRRRILDAAEECLLEHGYEAR
TH_3720|M.thermoresistible__bu ---------------------VTEATALETREAIIMGAFACFRTYGLRKT
Mvan_4342|M.vanbaalenii_PYR-1 ---MSMSVGTVPNSAGSNSAASARAEPGSVRDRLIDAAEQCLTAKGIRAT
MAV_2157|M.avium_104 MTSTRTAEFVRRLTEPDPVVLAQVDNPDEITARILAATLEQAELVGMRRT
MLBr_00064|M.leprae_Br4923 -----MINSTAGQTSQSRSRRSTRPSGDDRELAILATAEQLLEDRPLTEI
:: :
Mb2274c|M.bovis_AF2122/97 TLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIAAVLREVPLDGDDRE
MSMEG_4333|M.smegmatis_MC2_155 TLAEIARRAGVSRPTVYRRFPDTRSILAALLTARIVRVLDEVESDARGRE
Mflv_2773|M.gilvum_PYR-GCK TVTEIARRAGVSRPTIYRRWPDIRWVIAEVLTVRISDVLAAVPAAGPGRE
MMAR_4185|M.marinum_M GMNEIARAAGCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDID
MUL_4487|M.ulcerans_Agy99 GMNEIARAAGCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDID
Rv1255c|M.tuberculosis_H37Rv GMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVV
MAB_1036|M.abscessus_ATCC_1997 LHALIAKKAGLSRPTVYKHVGDQAAIIEALFHREFLRFGEMLEPVFAAAK
TH_3720|M.thermoresistible__bu TIVDIARKAEVSRSTVYEYFPDKAAIVEACAEAASERFYRNMAKVVNRGE
Mvan_4342|M.vanbaalenii_PYR-1 TVSEVAEVAGVSRGWLYRHFPDKAELLGAAIVRLNDAFWSESRTRLDAVA
MAV_2157|M.avium_104 TMEDVARRSGVGRATLYRRFPTKAALVDAVVLAEARRYLEGDAQAWAHGA
MLBr_00064|M.leprae_Br4923 SVDYLAKSAGISRPTFYFYFASKEAVLLTLLDRVFNKANAALETLIKNRD
:*. : .* .* :
Mb2274c|M.bovis_AF2122/97 AL------VKQIVAVADRLRGDD-LIMSVMHS--ELARVYITERLGTSQQ
MSMEG_4333|M.smegmatis_MC2_155 AL------VRRIVAVAERLRHDE-VIMAVLHTAPDVAMVYIAERLGTSQQ
Mflv_2773|M.gilvum_PYR-GCK EL------VDRVVRIAEHLRRDD-IVMSVIFNAPTLAMVYITERLGTSQQ
MMAR_4185|M.marinum_M DP------RDQLITSITATLRMV-RQRPALAAWFASTRPPIGGELAG-QS
MUL_4487|M.ulcerans_Agy99 DP------RDQLITSITATLRMV-RQRPALAAWFASTRPPIGGELAG-QS
Rv1255c|M.tuberculosis_H37Rv EP------AERLLVSITTTLRMV-RDNPALAAWFTTTRPPIGGEMAG-RS
MAB_1036|M.abscessus_ATCC_1997 NPRTG--FIDAIVRIVQHGRHHP-LLQKGLKENPEQVLPYLTVKARPFID
TH_3720|M.thermoresistible__bu DL------EDKLVRACVFVTQARRVVQGEKYFDEEEVSILLTRDSAVLLK
Mvan_4342|M.vanbaalenii_PYR-1 GLDQQ--IAVGVELARKESETPGALVLKLRQEEPEAFTACVGLGVRGLIP
MAV_2157|M.avium_104 TFEDR--MVNSTVFSVTFMREHA-LLKKLLRTEPETILPSLTVDAGVILD
MLBr_00064|M.leprae_Br4923 NKRGNKWRTGINVFFETFGSHKAVTCAGQVTRDNTEVRKLWSTFMQKWIS
Mb2274c|M.bovis_AF2122/97 VLIEGLAARLTVAQRSGSV---RSGDARRLATMVLLIAQSTIQSA-----
MSMEG_4333|M.smegmatis_MC2_155 ILIDAVAGEIKIAQEGGSV---RAGDARQLATMCLLITQSAIQSA-----
Mflv_2773|M.gilvum_PYR-GCK LLIDTLAAAIVQGQAHGSV---RAGDPHQMGAMCLLIAQSTIQSA-----
MMAR_4185|M.marinum_M EVIAGLAAAFLQSLGPEAP---AAVERRARWTVRVIVSLLMFPGQ-----
MUL_4487|M.ulcerans_Agy99 EVIAGLAAAFLQSLGPEAP---AAVERRARWTVRVIVSLLMFPGQ-----
Rv1255c|M.tuberculosis_H37Rv EVIAALAAAFLNSLGPDDP---TTVERRARWVVRMLTSLLMFPGR-----
MAB_1036|M.abscessus_ATCC_1997 QTTILLAPYFRQLLTEEQL---ASINVKAAAEWSFRIAASLLVTPGVVET
TH_3720|M.thermoresistible__bu ECADFIAPYLSAGRVTGEVR--KDLDIPKASEWVARILFSLFNTP-----
Mvan_4342|M.vanbaalenii_PYR-1 EIAAFWVPYIQAAVDRGEIH--PDTNSAEAAEWIARIMMSLATVP-----
MAV_2157|M.avium_104 YATEYTIGLLRRELYGTETTPSQERHLRTVAELHTRLTLSFIVTP-----
MLBr_00064|M.leprae_Br4923 YTAAVIDAERKRGVAPDTLP--ATELATALNLMNERALFASFTAEQ----
Mb2274c|M.bovis_AF2122/97 -------DIVDSILDSAALATELTHALNGYLC---------
MSMEG_4333|M.smegmatis_MC2_155 -------QMVAPILDADALARELAYSLNGYLKP--------
Mflv_2773|M.gilvum_PYR-GCK -------QMVEKFLDRDALNAELAHSLNGYLKP--------
MMAR_4185|M.marinum_M -------DEADERAMLEEFVAPVVTPFPTRR----------
MUL_4487|M.ulcerans_Agy99 -------DEADERAMLEEFVAPVVTPFPTRR----------
Rv1255c|M.tuberculosis_H37Rv -------DEADERAMIAEFVVPIVTPASAAARKAGHPGPE-
MAB_1036|M.abscessus_ATCC_1997 QTDEQLGDFIGNLLKVSAITEEISATVLAPDSAAS------
TH_3720|M.thermoresistible__bu ---SPTIDMSDDGAVADFVRSFVLRGFVDDRPHRGRRSSAG
Mvan_4342|M.vanbaalenii_PYR-1 ---GEQCNVDDHDSVLRHARRYIVAALRSDPNQ--------
MAV_2157|M.avium_104 -------HTSINLATVDDTRSYVRNYLMPMVVGPR------
MLBr_00064|M.leprae_Br4923 -------PHVPESRVLDTLVHIWVSSIYNEIR---------