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MTTSEIATLPGYEEFAPWLLVEKRGNVHVVSINRPEAFNAVNEQVHHAFATIWRVLTADDDVRAVVTTGV GKAFSAGGDMVMFGRLIDDAVARQFQISEARTVFLEVINFPKPLVSAVNGPAVGLGCSIALLSDFLVMGE SSYLADPHVAVGLVAGDGGAAMLPLLIGLMKAKEYVLLGDRITPAIADKLNLVTKVATDDTVLDEALAIG ERLAGLPPQALRASKVAMNMHLSRAALGVLEYALAEEYTSFSTPEFKERVAAFRARSKK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2558 | - | - | 100% (269) | enoyl-CoA hydratase |
| M. avium 104 | MAV_1818 | - | e-131 | 87.73% (269) | enoyl-CoA hydratase |
| M. avium 104 | MAV_0867 | - | 7e-53 | 45.42% (240) | enoyl-CoA hydratase/isomerase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2698 | echA15 | 1e-38 | 38.60% (228) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2395 | - | 2e-49 | 41.15% (243) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv2679 | echA15 | 1e-38 | 38.60% (228) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 8e-28 | 29.67% (246) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_1185c | - | 9e-28 | 29.53% (254) | enoyl-CoA hydratase |
| M. marinum M | MMAR_4790 | - | 5e-56 | 46.53% (245) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_5620 | - | 5e-60 | 45.42% (251) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3709 | - | 1e-137 | 91.45% (269) | PUTATIVE enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0359 | - | 5e-56 | 46.12% (245) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4253 | - | 2e-49 | 41.87% (246) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2698|M.bovis_AF2122/97 -------MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVGPHMHR
Rv2679|M.tuberculosis_H37Rv -------MPVTYDDFPSLRCEIHDQPGHEGVLELVLDSPGLNSVGPHMHR
MAV_2558|M.avium_104 ---MTTSEIATLPGYEEFAPWLLVEKRGNVHVVSINRPEAFNAVNEQVHH
TH_3709|M.thermoresistible__bu ---MTTSEIATLPGYEEFAPWLLVEKRGAVHVVSINRPEAFNAVNEEVHH
Mflv_2395|M.gilvum_PYR-GCK --------MYGMP--DEID----VTADGDLRIITLNRPDDLNAVNDNLHV
Mvan_4253|M.vanbaalenii_PYR-1 --------MYGMP--EEID----VRADGALRIITLNRPDDLNAVNDNLHV
MMAR_4790|M.marinum_M --------MYDMP--TEID----VRAEGALRIITLNRPDALNAVNDNLHV
MUL_0359|M.ulcerans_Agy99 --------MYDMP--TEID----VRAEGALRIITLNRPDALNAVNDNLHV
MSMEG_5620|M.smegmatis_MC2_155 -------MNYDVP--DELS----VSTDGPVRIVTINRETDLNSVNEKLHW
MLBr_02402|M.leprae_Br4923 ---MKYDTIL-------------VDGYQRVGIITLNRPQALNALNSQMMN
MAB_1185c|M.abscessus_ATCC_199 MTSHNFETIL-------------TERIDRVAVITLNRPKALNALNSQVMN
: : :*::. .:
Mb2698|M.bovis_AF2122/97 DLADIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIM
Rv2679|M.tuberculosis_H37Rv DLADIWPVIDRDPAVRVVLVRGEGKAFSSGGSFDLIAETIGDYQGRLRIM
MAV_2558|M.avium_104 AFATIWRVLTADDDVRAVVTTGVGKAFSAGGDMVMFGRLIDDAVARQFQI
TH_3709|M.thermoresistible__bu AFATIWRRLTDDEDVRAVVTTGVGKAFSAGGDMVMFGRLIEDPVARQFQI
Mflv_2395|M.gilvum_PYR-GCK GLAKIWEELNEDPGARAAVITGAGRAFSAGGDFHYLDELRRDEALRQKTI
Mvan_4253|M.vanbaalenii_PYR-1 GLAKIWEELNEDAGARAAVITGAGRAFSAGGDFNYLDELRNDEALRQKTI
MMAR_4790|M.marinum_M GLAGLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELSQDADLRAKTI
MUL_0359|M.ulcerans_Agy99 GLAGLWRRLSEDRSARAAVLTGAGRAFSAGGDFAYLAELAQDADLRAKTI
MSMEG_5620|M.smegmatis_MC2_155 ALANVWRQLAADKDAKVVVLTGAGRAFSAGGDLGWITTFLDDPVARDESI
MLBr_02402|M.leprae_Br4923 EITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFDADFF
MAB_1185c|M.abscessus_ATCC_199 EVTTAAAEFDADHGIGAIIITGSEKAFAAGADIKEMSEQSFSDMFGSDFF
.: : * . : * :.*::*..: : :
Mb2698|M.bovis_AF2122/97 REARDLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDG
Rv2679|M.tuberculosis_H37Rv REARDLVLNLVNFDKPVVSAIRGPAVGAGLVVALLADISVAGRAAKIIDG
MAV_2558|M.avium_104 SEARTVFLEVINFPKPLVSAVNGPAVGLGCSIALLSDFLVMGESSYLADP
TH_3709|M.thermoresistible__bu TEARTVFLEVINFPKPLVSAVNGPAVGLGCSIALLSDFLVMGRSSYLADP
Mflv_2395|M.gilvum_PYR-GCK KHGRDLVIGMVRCRIPVIAAVNGPAVGLGCSLAALSDVVYIAENAFFADP
Mvan_4253|M.vanbaalenii_PYR-1 KHGRDLVIGMVRCRIPVVAAVNGPAVGLGCSLAALSDVVYIAENAFFADP
MMAR_4790|M.marinum_M AHGRDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADP
MUL_0359|M.ulcerans_Agy99 AHGRDIVLGMARCRVPVVAAVNGPAVGLGCSLVALSDIVYIAPDAYLADP
MSMEG_5620|M.smegmatis_MC2_155 REGAQIIEEMLRFPLPVIAAVNGPAVGLGCSVALLCDILLISEDAYLADP
MLBr_02402|M.leprae_Br4923 SAWG----KLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQP
MAB_1185c|M.abscessus_ATCC_199 SAWG----KLGAVRTPTIAAVSGYALGGGCELAMMCDVIIAAENATFGQP
: * ::*: * *:* * :. :.*. . : : :
Mb2698|M.bovis_AF2122/97 HTKLGVAAGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICV
Rv2679|M.tuberculosis_H37Rv HTKLGVAAGDHAAICWPLLVGMAKAKYYLLTCEPLSGEEAERIGLVSICV
MAV_2558|M.avium_104 HVAVGLVAGDGGAAMLPLLIGLMKAKEYVLLGDRITPAIADKLNLVTKVA
TH_3709|M.thermoresistible__bu HVAVGLVAGDGGAAMLPLLIGLMKAKQYVLLGDRITPEEAEKLNLVTKVA
Mflv_2395|M.gilvum_PYR-GCK HVSIGLVAADGGPLVWGSQISLLQAKEFALTGVRIKAQKAVELGLANHVV
Mvan_4253|M.vanbaalenii_PYR-1 HVSIGLVAADGGPLVWGSQISLLQAKEFALTGVRIKAQRAVELGLANHVV
MMAR_4790|M.marinum_M HVQVGLVAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLVNHVA
MUL_0359|M.ulcerans_Agy99 HVQVGLVAADGGPLTWPLHISLMLAKEYALTGQRIAAQRAVELGLANHVA
MSMEG_5620|M.smegmatis_MC2_155 HVSVGLVAGDGGAALWPLLTPIMRSREFLYTGDRIDAGKAVELGLASRSV
MLBr_02402|M.leprae_Br4923 EIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVV
MAB_1185c|M.abscessus_ATCC_199 EIKLGVLPGMGGSQRLTRAIGKAKAMDMILTGRNMDAAEAERSGLVSRVV
. :*: .. .. : : * . .*.. .
Mb2698|M.bovis_AF2122/97 DDDDVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLE
Rv2679|M.tuberculosis_H37Rv DDDDVLPTATRLAERLAAGAQNAIRWTKRSLN-HWYRMFGPAFETSLGLE
MAV_2558|M.avium_104 TDDTVLDEALAIGERLAGLPPQALRASKVAMNMHLSRAALGVLEYALAEE
TH_3709|M.thermoresistible__bu EDDAVLDDALAIGERLAALPPQALRATKVAMNMHLSRAALGILEYALAEE
Mflv_2395|M.gilvum_PYR-GCK D--DPVGEAIACAKKIMALPQQAVEATKRLMNIQLEKSVMASLDYANLAE
Mvan_4253|M.vanbaalenii_PYR-1 D--DPVAEAIACAKKLIELPQQAVEATKRLMNIQLEKSVMASLDYANLAE
MMAR_4790|M.marinum_M A--DPVAEAVACAQRIMKLPQQAVESTKRVLNIHLERAVLASLDYALSAE
MUL_0359|M.ulcerans_Agy99 A--DPVAEAVACAQRIVKLPQQAVESTKRVLNIHLERAVLASLDYALSAE
MSMEG_5620|M.smegmatis_MC2_155 APGQLRSEAMTLAHRLAKQPVEALQGTKRVVNMYLSQVLSGPLQAGFAAE
MLBr_02402|M.leprae_Br4923 LADDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLF
MAB_1185c|M.abscessus_ATCC_199 ATESLLDEAKAVAKTISEMSLSASMMAKEAVNRAFESSLAEGLLFERRIF
* . : . .* :* :* :
Mb2698|M.bovis_AF2122/97 FIGFGGPDVREGLAAHREKRPARFGADPDPGAGS
Rv2679|M.tuberculosis_H37Rv FIGFGGPDVREGLAAHREKRPARFGADPDPGAGS
MAV_2558|M.avium_104 YTSFSTPEFKERVAAFRARSKK------------
TH_3709|M.thermoresistible__bu YTSFTTPEFQERVAAFRAKSNK------------
Mflv_2395|M.gilvum_PYR-GCK YVSFGTADFNRIVDGLIAKN--------------
Mvan_4253|M.vanbaalenii_PYR-1 YVSFGTADFNKIVDGLIAKK--------------
MMAR_4790|M.marinum_M HQSFTTEDFRSIVTRLTAPKN-------------
MUL_0359|M.ulcerans_Agy99 HQSFTTEDFRSIVTRLTAPKN-------------
MSMEG_5620|M.smegmatis_MC2_155 QVSMRSDDHRARLLAFKKKAHK------------
MLBr_02402|M.leprae_Br4923 HSTFVTDDQSEGMAAFIEKRAPQFTHR-------
MAB_1185c|M.abscessus_ATCC_199 HSAFGTADQSEGMAAFVEKRPANFIHR-------
: : :